Cowboys vs Eagles Prediction — AI Finds CAN'T MISS NFL Lines & Props (Sep 04)

Updated: 2025-08-28T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Dallas Cowboys kick off the 2025 NFL season on Thursday, September 4, by facing the defending Super Bowl champion Philadelphia Eagles at Lincoln Financial Field. Philadelphia enters as a 6.5‑point favorite (around –330 ML), while Dallas is a +265 underdog with the over/under set at 46.5 points.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Sep 04, 2025

Start Time: 8:20 PM EST​

Venue: Lincoln Financial Field​

Eagles Record: (0-0)

Cowboys Record: (0-0)

OPENING ODDS

DAL Moneyline: +261

PHI Moneyline: -329

DAL Spread: +7

PHI Spread: -7.0

Over/Under: 46.5

DAL
Betting Trends

  • Dallas, under new head coach Brian Schottenheimer, opens as underdogs and have historically been competitive in that role, though their form has been mixed—last season they posted a 7–10 record and were routinely outmatched by Philly.

PHI
Betting Trends

  • Philadelphia has covered as favorites in season openers at a clip of 15–5 since 2004, and enters this game with strong home and playoff momentum after a dominant Super Bowl run last year.

MATCHUP TRENDS

  • In their two meetings last season, the Eagles outscored Dallas 75–13—a staggering dominance that included a 41–7 victory at AT&T Stadium. Under new QB Dak Prescott’s projected return, the Cowboys are looking to break that pattern.

DAL vs. PHI
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: S. Barkley over 96.5 Rushing Yards.

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Dallas vs Philadelphia Prediction & Odds:
Free NFL Betting Insights for 9/4/25

The season opener between the Dallas Cowboys and Philadelphia Eagles on September 4, 2025, at Lincoln Financial Field is more than just a Week 1 clash—it’s a renewal of one of the NFL’s fiercest rivalries and a test of whether Dallas’s offseason reset can close the gap on the reigning Super Bowl champions. The Eagles enter as 6.5-point home favorites fresh off their Super Bowl LIX title and an 18-win season that saw them dominate both sides of the ball with a top-three scoring defense and an MVP-caliber campaign from quarterback Jalen Hurts. They return their core from last season, including Hurts, DeVonta Smith, A.J. Brown, and new addition Saquon Barkley, alongside a retooled but still dangerous defense led by Darius Slay and a rising crop of young defenders. The Cowboys, meanwhile, are coming off a disappointing 7–10 finish and a complete overhaul in leadership, promoting Brian Schottenheimer to head coach and hoping for a fresh start with a healthy Dak Prescott back under center. Prescott missed both games against Philadelphia last year due to injury—games that resulted in a combined 75–13 beatdown in favor of the Eagles—but his return brings needed stability and the hope of competitiveness, especially with offseason addition George Pickens lining up alongside CeeDee Lamb. Still, Dallas will face an uphill climb against a team that thrives at home in prime time, with the Eagles boasting a 15–5 record in season openers over the last two decades and a fan base that turns Lincoln Financial Field into one of the loudest venues in football.

The matchup will likely hinge on several key factors: whether Prescott can withstand the Eagles’ relentless pass rush, whether Dallas’s offensive line—featuring rookie Tyler Booker—can hold up against Philly’s front seven, and if the Cowboys’ defense can generate takeaways against a low-mistake offense. Philly will aim to control the tempo by establishing the run with Barkley, forcing Dallas into a time-of-possession deficit and then unleashing its blitz-heavy packages to create pressure and potential turnovers. For Dallas to stay within striking distance, they’ll need to avoid the early-game collapses that plagued them last year, capitalize on any red zone trips, and hope for an inspired defensive performance from Micah Parsons and Trevon Diggs to contain Philly’s weapons. With an over/under set at 46.5, oddsmakers anticipate a moderately paced game that favors balanced attacks and disciplined execution, which could benefit Philadelphia given their continuity and proven championship formula. Ultimately, while the Eagles have the edge in nearly every category—coaching stability, recent performance, roster depth, and quarterback momentum—the Cowboys have the wild card of unpredictability with Prescott’s return and a new coaching staff with nothing to lose. Whether that proves enough to pull off a Week 1 stunner remains to be seen, but Dallas will need its best version from the opening whistle to avoid a repeat of last year’s lopsided results. In a rivalry that rarely disappoints in drama, Thursday night could either signal a changing of the NFC East tide or reinforce Philadelphia’s continued reign over the division and the conference.

Dallas Cowboys NFL Preview

The Dallas Cowboys enter the 2025 NFL season under the leadership of new head coach Brian Schottenheimer and begin their campaign with a daunting task: facing the defending Super Bowl champion Philadelphia Eagles on the road in prime time. After finishing the 2024 season with a disappointing 7–10 record, the Cowboys have undergone significant changes, most notably welcoming back quarterback Dak Prescott, who missed most of last season due to injury. Prescott’s return brings hope to a franchise desperate to rebound, and he’ll be joined by rising star George Pickens, acquired in the offseason, who is expected to line up alongside CeeDee Lamb to form a potentially dynamic receiving duo. The offensive line features rookie left guard Tyler Booker, who will be tested early against Philadelphia’s ferocious front seven. Dallas’s offensive strategy will likely center around short, controlled passes and quick reads to minimize pressure, as well as using Tony Pollard’s elusiveness out of the backfield to keep the defense honest. Defensively, the Cowboys will need game-changing performances from Micah Parsons, who remains their most disruptive player, and Trevon Diggs, whose ball-hawking skills could be critical in turning the tide against a high-powered Eagles offense. However, Dallas’s defense struggled last year against mobile quarterbacks, and Jalen Hurts presents a multidimensional threat that will require discipline and airtight containment.

The Cowboys were outscored 75–13 by the Eagles across two meetings in 2024, both without Prescott, and they’ll need a near-flawless performance to keep pace this time around. Their ability to execute on third down, win the turnover battle, and prevent explosive plays will determine whether they can compete or collapse under pressure. The coaching transition adds another variable, as Schottenheimer’s play-calling tendencies and game management will be under intense scrutiny right out of the gate. Betting trends don’t favor Dallas in this spot, especially on the road against an elite team, but their unpredictable nature and the return of their franchise quarterback give them a glimmer of hope to at least cover the spread and possibly spring an upset. The Cowboys’ approach must emphasize efficiency, ball control, and minimizing self-inflicted errors—penalties and red zone misfires doomed them repeatedly last year, and repeating those mistakes against Philadelphia could result in another blowout. The team’s special teams, led by kicker Brandon Aubrey, must also be sharp, as field position and clock management could be critical in what they hope to turn into a grind-it-out, low-possession contest. While the odds are against them, the Cowboys are still talented enough to make this a game if everything clicks—Prescott reclaims his form, the defense generates a turnover or two, and the offensive line holds firm. In the harsh environment of Lincoln Financial Field, how the Cowboys handle the opening quarter—mentally and physically—could very well decide whether they remain competitive or fall into the same nightmare scenario they experienced twice last year.

The Dallas Cowboys kick off the 2025 NFL season on Thursday, September 4, by facing the defending Super Bowl champion Philadelphia Eagles at Lincoln Financial Field. Philadelphia enters as a 6.5‑point favorite (around –330 ML), while Dallas is a +265 underdog with the over/under set at 46.5 points. Dallas vs Philadelphia AI Prediction: Free NFL Betting Insights for Sep 04. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Philadelphia Eagles NFL Preview

The Philadelphia Eagles begin their 2025 title defense with confidence and continuity as they host division rival Dallas Cowboys in the NFL’s season opener at Lincoln Financial Field, bringing back the majority of their Super Bowl-winning core and maintaining the structure that delivered an 18-win campaign in 2024. Quarterback Jalen Hurts remains the central figure of the offense after an MVP-caliber season where he threw for over 4,500 yards and 37 touchdowns while rushing for nearly 700 more, combining poise, strength, and field command in both pocket and improvisational settings. Hurts is surrounded by top-tier weapons in A.J. Brown, DeVonta Smith, and Dallas Goedert, and the addition of Saquon Barkley in the backfield further elevates the offensive potential with a dual-threat option who can contribute in both the run game and as a receiver. Philadelphia’s offensive line, led by Jordan Mailata and Landon Dickerson, remains among the league’s most disciplined and effective in both pass protection and run blocking, and their ability to control the line of scrimmage has been a foundational reason for the team’s consistent success. Defensively, the Eagles are just as formidable, with Vic Fangio’s unit returning most of its key players including Haason Reddick, Josh Sweat, and Darius Slay, while rookies like Quinyon Mitchell add young athleticism and versatility to a unit already built to stop the run and challenge opposing pass games.

Philadelphia’s defense held opponents under 18 points per game last season and ranked top-five in takeaways, and their aggressive approach forces quarterbacks to make fast, often dangerous decisions. They’re also statistically dominant in season openers, having gone 15–5 in Week 1 since 2004 and thriving in home primetime matchups where crowd energy and execution precision are at a peak. On special teams, kicker Jake Elliott remains reliable from distance, while the return unit continues to offer field-flipping potential. Against Dallas, Philadelphia will look to establish control early by running the ball with Barkley, then hitting explosive plays over the top once safeties are forced to creep in—an area where Brown and Smith thrive. Defensively, the goal will be to pressure Dak Prescott early, limit CeeDee Lamb’s effectiveness by bracketing coverage, and keep George Pickens from finding rhythm on deeper routes. The Cowboys’ new head coach and changes along the offensive line provide some unknowns, but Philadelphia’s experience, coaching stability, and ability to exploit mismatches give them a clear advantage both tactically and psychologically. Having routed Dallas twice last year by a combined 62 points, the Eagles will aim to quickly reassert division dominance and set the tone for another championship chase. They’ll also look to use this game as a statement—the kind that reminds the league that the Super Bowl run was no fluke, and the NFC still runs through Philadelphia. If Hurts plays to form, the defense harasses Prescott, and Barkley opens up the offense as expected, the Eagles could make this opener another lopsided showcase of their completeness and superiority in all three phases.

Dallas vs. Philadelphia Prop Picks (AI)

Remi is pouring through loads of data on each player. In fact, anytime the Cowboys and Eagles play there’s always several intriguing angles to key in on. Not to mention games played at Lincoln Financial Field in Sep rarely follow normal, predictable patterns.
Remi's searched hard and found the best prop for this matchup: S. Barkley over 96.5 Rushing Yards.

Dallas vs. Philadelphia Prediction (AI)

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Remi, our AI sports wizard, has been pouring over millions of data from every facet between the Cowboys and Eagles and using recursive machine learning and impressive AI to examine the data to a single cover probability.

Oddly enough, we’ve seen the AI has been most focused on the linear correlation of emphasis human bettors regularly put on player performance factors between a Cowboys team going up against a possibly improved Eagles team. We’ve found the true game analytics appear to reflect a strong lean against one Vegas line specifically.

Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.

Below is our current AI Dallas vs Philadelphia picks, computer picks Cowboys vs Eagles, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
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Cowboys Betting Trends

Dallas, under new head coach Brian Schottenheimer, opens as underdogs and have historically been competitive in that role, though their form has been mixed—last season they posted a 7–10 record and were routinely outmatched by Philly.

Eagles Betting Trends

Philadelphia has covered as favorites in season openers at a clip of 15–5 since 2004, and enters this game with strong home and playoff momentum after a dominant Super Bowl run last year.

Cowboys vs. Eagles Matchup Trends

In their two meetings last season, the Eagles outscored Dallas 75–13—a staggering dominance that included a 41–7 victory at AT&T Stadium. Under new QB Dak Prescott’s projected return, the Cowboys are looking to break that pattern.

Dallas vs. Philadelphia Game Info

Dallas vs Philadelphia starts on September 04, 2025 at 8:20 PM EST.

Venue: Lincoln Financial Field.

Spread: Philadelphia -7.0
Moneyline: Dallas +261, Philadelphia -329
Over/Under: 46.5

Dallas: (0-0)  |  Philadelphia: (0-0)

Remi's searched hard and found the best prop for this matchup: S. Barkley over 96.5 Rushing Yards.. Prices move—always shop for the best number.

In their two meetings last season, the Eagles outscored Dallas 75–13—a staggering dominance that included a 41–7 victory at AT&T Stadium. Under new QB Dak Prescott’s projected return, the Cowboys are looking to break that pattern.

DAL trend: Dallas, under new head coach Brian Schottenheimer, opens as underdogs and have historically been competitive in that role, though their form has been mixed—last season they posted a 7–10 record and were routinely outmatched by Philly.

PHI trend: Philadelphia has covered as favorites in season openers at a clip of 15–5 since 2004, and enters this game with strong home and playoff momentum after a dominant Super Bowl run last year.

See our latest NFL picks and odds pages for 2025 to compare prices before you bet.

Dallas vs. Philadelphia Odds

Remi is pouring through loads of data points on each team. In fact, anytime the Dallas vs Philadelphia trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme altitude can often follow normal, predictable betting trends.

Dallas vs Philadelphia Opening Odds

DAL Moneyline: +261
PHI Moneyline: -329
DAL Spread: +7
PHI Spread: -7.0
Over/Under: 46.5

Dallas vs Philadelphia Live Odds

Games PTS ML SPR O/U
Oct 30, 2025 8:15PM EDT
Baltimore Ravens
Miami Dolphins
10/30/25 8:15PM
Ravens
Dolphins
-440
+344
-7.5 (-110)
+7.5 (-110)
O 51 (-105)
U 51 (-115)
Nov 2, 2025 1:00PM EST
Chicago Bears
Cincinnati Bengals
11/2/25 1PM
Bears
Bengals
-160
+140
-2.5 (-125)
+2.5 (+105)
O 51.5 (-104)
U 51.5 (-116)
Nov 2, 2025 1:00PM EST
Indianapolis Colts
Pittsburgh Steelers
11/2/25 1PM
Colts
Steelers
-171
+150
-3 (-117)
+3 (-103)
O 50.5 (-110)
U 50.5 (-110)
Nov 2, 2025 1:00PM EST
Carolina Panthers
Green Bay Packers
11/2/25 1PM
Panthers
Packers
+613
-900
+13 (-105)
-13 (-115)
O 44 (-110)
U 44 (-110)
Nov 2, 2025 1:00PM EST
Atlanta Falcons
New England Patriots
11/2/25 1PM
Falcons
Patriots
+207
-250
+5 (-105)
-5 (-115)
O 45 (-110)
U 45 (-110)
Nov 2, 2025 1:00PM EST
Denver Broncos
Houston Texans
11/2/25 1PM
Broncos
Texans
+105
-125
+1 (+100)
-1 (-120)
O 40 (-110)
U 40 (-110)
Nov 2, 2025 1:00PM EST
San Francisco 49ers
New York Giants
11/2/25 1PM
49ers
Giants
-147
+127
-2.5 (-115)
+2.5 (-105)
O 49 (-103)
U 49 (-117)
Nov 2, 2025 1:00PM EST
Los Angeles Chargers
Tennessee Titans
11/2/25 1PM
Chargers
Titans
-500
+383
-9.5 (-105)
+9.5 (-115)
O 43.5 (-108)
U 43.5 (-112)
Nov 2, 2025 1:00PM EST
Minnesota Vikings
Detroit Lions
11/2/25 1PM
Vikings
Lions
+374
-485
+9 (-110)
-9 (-110)
O 47.5 (-117)
U 47.5 (-103)
Nov 2, 2025 4:05PM EST
New Orleans Saints
Los Angeles Rams
11/2/25 4:05PM
Saints
Rams
+754
-1200
+13.5 (+100)
-13.5 (-120)
O 44 (-107)
U 44 (-113)
Nov 2, 2025 4:05PM EST
Jacksonville Jaguars
Las Vegas Raiders
11/2/25 4:05PM
Jaguars
Raiders
-150
+130
-3 (+100)
+3 (-120)
O 44.5 (-110)
U 44.5 (-110)
Nov 2, 2025 4:25PM EST
Kansas City Chiefs
Buffalo Bills
11/2/25 4:25PM
Chiefs
Bills
-130
+110
-2 (-110)
+2 (-110)
O 52.5 (-110)
U 52.5 (-110)
Nov 2, 2025 8:20PM EST
Seattle Seahawks
Washington Commanders
11/2/25 8:20PM
Seahawks
Commanders
-163
+143
-3 (-113)
+3 (-107)
O 48 (-110)
U 48 (-110)
Nov 3, 2025 8:15PM EST
Arizona Cardinals
Dallas Cowboys
11/3/25 8:15PM
Cardinals
Cowboys
+130
-150
+2.5 (-105)
-2.5 (-115)
O 53.5 (-105)
U 53.5 (-115)
Nov 6, 2025 8:15PM EST
Las Vegas Raiders
Denver Broncos
11/6/25 8:15PM
Raiders
Broncos
+370
-480
+9.5 (-106)
-9.5 (-114)
O 42.5 (-110)
U 42.5 (-110)
Nov 9, 2025 9:30AM EST
Atlanta Falcons
Indianapolis Colts
11/9/25 9:30AM
Falcons
Colts
+290
-360
+7 (-106)
-7 (-114)
O 48.5 (-110)
U 48.5 (-110)

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We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Dallas Cowboys vs. Philadelphia Eagles on September 04, 2025 at Lincoln Financial Field.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our NFL odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
TB@NO TB -3.5 52.3% 1 WIN
GB@PIT GB -2.5 52.3% 1 WIN
SF@HOU SF +2.5 56.0% 6 LOSS
NYG@PHI NYG +7.5 53.9% 3 LOSS
BUF@CAR CAR +7.5 54.2% 3 LOSS
DAL@DEN DAL +3.5 55.0% 4 LOSS
MIA@ATL MIA +7 54.3% 4 WIN
CLE@NE CLE +7 56.8% 6 LOSS
TB@NO BAKER MAYFIELD OVER 15.5 RUSH YDS 56.6% 6 LOSS
MIN@LAC JUSTIN HERBERT PASS ATT UNDER 35.5 55.5% 5 WIN
TB@DET TB +6.5 54.4% 4 LOSS
TB@DET RACHAAD WHITE UNDER 14.5 RUSH ATT 54.4% 4 WIN
NE@TEN NE -6.5 55.2% 5 WIN
CAR@NYJ CAR -110 57.4 4 WIN
PHI@MIN PHI -130 58.0% 6 WIN
GB@ARI ARI +7 54.8% 5 WIN
NO@CHI NO +4.5 57.4% 7 LOSS
WAS@DAL JAYDEN DANIELS 1H RUSH YDS OVER 22.5 56.1% 5 WIN
GB@ARI JORDAN LOVE 1Q PASS YDS OVER 54.5 56.6% 6 WIN
PIT@CIN JONNU SMITH RECEPTIONS OVER 3.5 55.3% 5 LOSS
BUF@ATL BUF -3.5 54.7% 4 LOSS
CHI@WAS JAYDEN DANIELS OVER 1.5 PASS TDS 56.6% 6 WIN
TEN@LV UNDER 42 54.8% 3 WIN
DET@KC DET +2.5 55.7% 7 LOSS
SEA@JAC SEA -112 55.7% 5 WIN
LAC@MIA LAC -3.5 54.0% 3 LOSS
ARI@IND IND -8.5 55.6% 5 LOSS
TEN@LV TEN +4.5 56.7% 6 LOSS
LAR@BAL LAR -7 56.2% 6 WIN
SF@TB SF +3.5 57.2% 7 LOSS
CLE@PIT JAYLEN WARREN UNDER 46.5 RUSH YDS 54.4% 4 LOSS
DEN@NYJ BREECE HALL OVER 26.5 RECV YDS 55.0% 4 LOSS
KC@JAC UNDER 45.5 54.9% 3 LOSS
KC@JAC PATRICK MAHOMES UNDER 23.5 PASS COMP 56.6% 6 LOSS
HOU@BAL HOU -125 58.5% 7 WIN
DET@CIN DET -10 55.6% 5 WIN
DAL@NYJ NYJ +1.5 53.7% 3 LOSS
TB@SEA TB +3.5 54.9% 4 WIN
TEN@ARI ARI -7 (BUY 0.5) 54.9% 4 LOSS
DEN@PHI DEN +4.5 57.5% 7 WIN
MIA@CAR TETAIROA MCMILLAN OVER 58.5 RECV YDS 54.5% 4 WIN
LV@IND ASHTON JEANTY UNDER 67.5 RUSH YDS 54.4% 4 WIN
SF@LAR DEMARCUS ROBINSON OVER 29.5 RECV YDS 55.7% 5 WIN
NYJ@MIA NYJ +3 53.8 3 LOSS
CIN@DEN DEN -7.5 54.8 4 WIN
NYJ@MIA OVER 44 52.9% 2 WIN
CIN@DEN UNDER 44.5 53.7% 3 WIN
NYJ@MIA GARRETT WILSON UNDER 9 TARGETS 53.7% 3 WIN
CIN@DEN TEE HIGGINS OVER 6.5 RECV TARGETS 55.5% 5 LOSS
WAS@ATL ATL -2.5 54.3 4 WIN
BAL@KC BAL -2.5 56.3% 6 LOSS