Pacers vs Knicks Prediction — AI Finds CAN'T MISS NBA Lines & Props (May 21)
Updated: 2025-05-19T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Indiana Pacers and New York Knicks will clash in Game 1 of the Eastern Conference Finals on Wednesday, May 21, 2025, at Madison Square Garden. This series marks a rematch of last year’s playoff encounter, where the Pacers triumphed in seven games, setting the stage for a highly anticipated showdown.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: May 21, 2025
Start Time: 8:00 PM EST
Venue: Madison Square Garden
Knicks Record: (51-31)
Pacers Record: (50-32)
OPENING ODDS
IND Moneyline: +155
NY Moneyline: -186
IND Spread: +4.5
NY Spread: -4.5
Over/Under: 223.5
IND
Betting Trends
- The Indiana Pacers have a 40-42-2 record against the spread (ATS) this season, indicating a near-even performance in covering the spread.
NY
Betting Trends
- The New York Knicks hold a 48-38-3 ATS record this season, reflecting a strong ability to surpass betting expectations.
MATCHUP TRENDS
- Despite the Knicks being -145 favorites, 78% of the total money wagered is backing New York, suggesting strong public confidence in their victory.
IND vs. NY
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: P. Siakam over 28.5 PTS+REB+AST.
LIVE NBA ODDS
NBA ODDS COMPARISON
WANT MORE AI PICKS?
VS. SPREAD
323-240
NET UNITS
(INCL VIG)
+384.5
NET PROFIT
(INCL VIG)
$100/UNIT
$38,448
VS. SPREAD
1593-1364
NET UNITS
(INCL VIG)
+371.9
NET PROFIT
(INCL VIG)
$100/UNIT
$37,192
AI SPORTS PICK PRODUCTS
Create a Free Account

Remi Finds New Picks

Remi Works 24/7
Remi uses this probability to assign units to each pick.
Get Remi's AI Picks
Get Remi’s Top AI Sports Picks sent direct to your inbox.
Hedge Meaning in Betting | 4 Obvious Times to Hedge
Learn about hedge betting to manage risk and secure profits. Understand...
What is a Push in Betting? | 3 Ways To Use To Your Advantage
Understand what a push in betting means, how it happens in...
What Does the + and – Mean in Sports Betting? | 5 Easy Tips
Learn the basics of sports betting odds, what the plus (+)...
Indiana vs New York Prediction & Odds:
Free NBA Betting Insights for 5/21/25
Their path to the Conference Finals has not been easy—having taken down the Miami Heat and Boston Celtics—but they’ve emerged with the battle scars and belief of a contender. The Knicks rank fifth in playoff defensive efficiency, bolstered by elite rebounding and physical on-ball defenders like Josh Hart and OG Anunoby. They thrive on slowing the game down, executing in the half-court, and grinding opponents into submission. This series will be a study in contrasting philosophies: the Pacers aim to speed up the game, force turnovers, and attack in early offense, while the Knicks will look to control tempo, limit possessions, and make every trip down the floor a half-court slugfest. Key factors to watch include whether Indiana can maintain their pace against New York’s structured defense, how well the Knicks’ starters hold up over what could be a long series, and whether either team can gain an edge on the boards. The Pacers’ bench depth may tilt certain games in their favor, but the Knicks’ home-court advantage at Madison Square Garden—where they’ve been exceptional—can’t be underestimated. With both teams carrying legitimate momentum, passionate fan bases, and physical, playoff-hardened cores, this series is expected to be tightly contested, emotional, and potentially a seven-game thriller. Whoever wins will have earned their spot in the NBA Finals through resilience, poise, and timely execution under pressure.
the top plays of last year’s dub over the Knicks in the Eastern Conference Semifinals 😤 pic.twitter.com/GOK1Q55YHA
— Indiana Pacers (@Pacers) May 19, 2025
Indiana Pacers NBA Preview
The Indiana Pacers enter the Eastern Conference Finals as one of the most exhilarating and relentless teams of the 2025 NBA Playoffs, powered by a breakneck offense, deep bench, and the elite leadership of Tyrese Haliburton. Their unexpected but dominant run through the Eastern bracket has seen them outpace the Bucks and outclass the top-seeded Cavaliers in just five games, establishing them as a force that’s not merely hot but built for the postseason. Haliburton has been the central engine of this movement, averaging over 22 points and 9 assists per game in the playoffs while controlling tempo, distributing with flair, and making clutch buckets when needed. But what makes the Pacers so dangerous isn’t just their superstar—it’s the cohesion and depth of their roster. Pascal Siakam has slotted in seamlessly as both a versatile scorer and veteran presence, while Myles Turner’s rim protection and floor spacing have been crucial in neutralizing opposing bigs. Andrew Nembhard and Bennedict Mathurin have shined on both ends, providing spark, perimeter defense, and shot-making that make Indiana’s rotation one of the deepest left in the postseason. Coach Rick Carlisle has leveraged a 10-man rotation better than any other team this postseason, keeping legs fresh and the pace high into the fourth quarter. The Pacers average over 118 points per game in the playoffs, using fast-break opportunities, early clock threes, and quick rim attacks to overwhelm opponents before defenses can even set.
Defensively, they’ve made quiet but steady improvements, climbing to eighth in playoff defensive efficiency, a testament to their growing chemistry and effort on that end. Nembhard, in particular, has emerged as a capable perimeter stopper who will be tasked with slowing down Jalen Brunson throughout the series. The Pacers will need to continue creating turnovers and converting in transition to mitigate the Knicks’ half-court grind, especially considering New York’s physical style and the intimidating environment of Madison Square Garden. Another challenge will be rebounding—while Turner and Siakam are active on the boards, they’ll need all five players crashing the glass to avoid giving second-chance points to a rugged Knicks frontcourt. Yet Indiana’s ability to counterpunch quickly, knock down threes at volume, and exploit mismatches in transition gives them a blueprint for success, even on the road. Their 21-20 away record in the regular season is respectable, but they’ve shown in these playoffs that they’re unbothered by hostile crowds and tight finishes. If Haliburton continues to control pace, Siakam maintains his inside-out dominance, and the bench delivers its usual spark, the Pacers could very well steal Game 1 and flip the pressure squarely onto the Knicks. Indiana has become more than a feel-good story—they’re a team with elite talent, purpose, and belief, and they arrive in New York ready to run, gun, and take the next step toward an NBA Finals berth.

Credit: USA TODAY/IMAGN
New York Knicks NBA Preview
The New York Knicks return to the Eastern Conference Finals riding a wave of gritty, battle-tested momentum that has defined their 2025 postseason identity, shaped by the steely leadership of Jalen Brunson, the versatile presence of Karl-Anthony Towns, and the relentless culture instilled by head coach Tom Thibodeau. The Knicks fought through a physical six-game series against the Boston Celtics after eliminating the Miami Heat, demonstrating a signature brand of tough, defensive-minded basketball backed by timely scoring and elite execution in clutch moments. At the center of their run is Brunson, who has transformed into a full-fledged superstar and the emotional engine of the franchise. His poise in crunch time, efficient mid-range scoring, and uncanny ability to get to his spots have made him a nightmare for opposing guards, and his leadership has galvanized a roster that thrives in adversity. Alongside him, Towns has brought needed frontcourt versatility—stretching the floor with his shooting while also punishing mismatches in the post. RJ Barrett and Josh Hart have both stepped up as secondary scoring options, with Hart particularly embodying the Knicks’ rugged defensive identity through hustle plays, rebounding, and perimeter coverage. Defensively, New York has been elite, ranking fifth in playoff defensive efficiency, using aggressive closeouts, physical post defense, and sharp rotations to limit opponents’ clean looks. Mitchell Robinson and Isaiah Hartenstein have formed a formidable rim-protecting tandem, controlling the paint and giving the Knicks a rebounding edge nearly every night.
While the Knicks deploy a tighter rotation than most playoff teams—usually leaning on 7–8 players—Thibodeau’s emphasis on conditioning and accountability ensures his core group is prepared to play heavy minutes at a high level. This structure works especially well at Madison Square Garden, where the Knicks are 27-14 this season and feed off one of the NBA’s most passionate crowds. Against the Pacers, New York’s focus will be on controlling tempo, slowing down Indiana’s league-best transition offense, and forcing them into difficult half-court sets. Brunson will likely be defended by Andrew Nembhard, a strong on-ball guard, but the Knicks will run multiple pick-and-roll variations and off-ball sets to get Brunson clean looks and create switches they can exploit. Limiting Tyrese Haliburton’s playmaking and stopping Indiana’s bench from changing the game’s pace will be priorities on defense. While the Pacers’ depth and speed are dangerous, the Knicks hold the edge in physicality, rebounding, and half-court execution—areas that tend to define playoff series as they progress. New York also benefits from the experience of last year’s seven-game battle with Indiana, a series they lost but learned from, and the core group returns this time smarter, stronger, and with a deeper hunger to break through. If Brunson continues his All-NBA form and Towns remains aggressive on both ends, the Knicks are positioned not only to protect home court but to seize control of this series from the outset, inching one step closer to their first NBA Finals appearance since 1999.
when you realize it's GAME WEEK 😁 pic.twitter.com/JwY7CuZHIC
— NEW YORK KNICKS (@nyknicks) May 19, 2025
Indiana vs. New York Prop Picks (AI)
Indiana vs. New York Prediction (AI)

Remi, our AI sports wizard, has been pouring over millions of data from every facet between the Pacers and Knicks and using recursive machine learning and industry leading AI to analyze the data to a single cover probability.
Remi has been most keyed in on the linear correlation of weight emotional bettors often put on New York’s strength factors between a Pacers team going up against a possibly deflated Knicks team. We’ve found the true game analytics appear to reflect a moderate lean against one Vegas line specifically.
Unlock this in-depth AI prediction and all of our NBA AI picks for FREE now.
Below is our current AI Indiana vs New York picks, computer picks Pacers vs Knicks, best bets, model edges, confidence ratings.
![]() |
DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
---|---|---|---|---|---|---|
ACTIVE PICKS LOCKED - SEE NOW |
These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NBA schedule.
Pacers Betting Trends
The Indiana Pacers have a 40-42-2 record against the spread (ATS) this season, indicating a near-even performance in covering the spread.
Knicks Betting Trends
The New York Knicks hold a 48-38-3 ATS record this season, reflecting a strong ability to surpass betting expectations.
Pacers vs. Knicks Matchup Trends
Despite the Knicks being -145 favorites, 78% of the total money wagered is backing New York, suggesting strong public confidence in their victory.
Indiana vs. New York Game Info
What time does Indiana vs New York start on May 21, 2025?
Indiana vs New York starts on May 21, 2025 at 8:00 PM EST.
Where is Indiana vs New York being played?
Venue: Madison Square Garden.
What are the opening odds for Indiana vs New York?
Spread: New York -4.5
Moneyline: Indiana +155, New York -186
Over/Under: 223.5
What are the records for Indiana vs New York?
Indiana: (50-32) | New York: (51-31)
What is the AI best bet for Indiana vs New York?
Remi's searched hard and found the best prop for this matchup: P. Siakam over 28.5 PTS+REB+AST.. Prices move—always shop for the best number.
What are Indiana vs New York trending bets?
Despite the Knicks being -145 favorites, 78% of the total money wagered is backing New York, suggesting strong public confidence in their victory.
What are Indiana trending bets?
IND trend: The Indiana Pacers have a 40-42-2 record against the spread (ATS) this season, indicating a near-even performance in covering the spread.
What are New York trending bets?
NY trend: The New York Knicks hold a 48-38-3 ATS record this season, reflecting a strong ability to surpass betting expectations.
Where can I find AI Picks for Indiana vs New York?
See our latest NBA picks and odds pages for 2025 to compare prices before you bet.
Indiana vs. New York Odds
Remi is pouring through tons of stats on each team. In fact, anytime the Indiana vs New York trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme altitude seemingly never follow normal, predictable patterns.
Indiana vs New York Opening Odds
IND Moneyline:
+155 NY Moneyline: -186
IND Spread: +4.5
NY Spread: -4.5
Over/Under: 223.5
Indiana vs New York Live Odds
Games | PTS | ML | SPR | O/U | |
---|---|---|---|---|---|
Oct 21, 2025 7:35PM EDT
Houston Rockets
Oklahoma City Thunder
10/21/25 7:35PM
Rockets
Thunder
|
–
–
|
+245
-300
|
+7.5 (-110)
-7.5 (-110)
|
O 226.5 (-115)
U 226.5 (-105)
|
|
Oct 21, 2025 10:00PM EDT
Golden State Warriors
Los Angeles Lakers
10/21/25 10PM
Warriors
Lakers
|
–
–
|
-130
+110
|
-2 (-110)
+2 (-110)
|
O 224.5 (-110)
U 224.5 (-110)
|
|
Oct 22, 2025 7:10PM EDT
Brooklyn Nets
Charlotte Hornets
10/22/25 7:10PM
Nets
Hornets
|
–
–
|
+150
-180
|
+4.5 (-110)
-4.5 (-110)
|
O 225.5 (-110)
U 225.5 (-110)
|
|
Oct 22, 2025 7:10PM EDT
Cleveland Cavaliers
New York Knicks
10/22/25 7:10PM
Cavaliers
Knicks
|
–
–
|
+140
-170
|
+3.5 (-105)
-3.5 (-115)
|
O 229.5 (-110)
U 229.5 (-110)
|
|
Oct 22, 2025 7:10PM EDT
Miami Heat
Orlando Magic
10/22/25 7:10PM
Heat
Magic
|
–
–
|
+280
-350
|
+8 (-110)
-8 (-110)
|
O 215.5 (-110)
U 215.5 (-110)
|
|
Oct 22, 2025 7:40PM EDT
Philadelphia 76ers
Boston Celtics
10/22/25 7:40PM
76ers
Celtics
|
–
–
|
+115
-140
|
+2.5 (-110)
-2.5 (-110)
|
O 225.5 (-110)
U 225.5 (-110)
|
|
Oct 22, 2025 7:40PM EDT
Toronto Raptors
Atlanta Hawks
10/22/25 7:40PM
Raptors
Hawks
|
–
–
|
+190
-240
|
+6 (-110)
-6 (-110)
|
O 235.5 (-110)
U 235.5 (-110)
|
|
Oct 22, 2025 8:10PM EDT
Washington Wizards
Milwaukee Bucks
10/22/25 8:10PM
Wizards
Bucks
|
–
–
|
+300
-375
|
+9 (-110)
-9 (-110)
|
O 228.5 (-110)
U 228.5 (-110)
|
|
Oct 22, 2025 8:10PM EDT
Detroit Pistons
Chicago Bulls
10/22/25 8:10PM
Pistons
Bulls
|
–
–
|
-140
+115
|
-2 (-110)
+2 (-110)
|
O 235 (-110)
U 235 (-110)
|
|
Oct 22, 2025 8:10PM EDT
New Orleans Pelicans
Memphis Grizzlies
10/22/25 8:10PM
Pelicans
Grizzlies
|
–
–
|
+130
-160
|
+3.5 (-110)
-3.5 (-110)
|
O 237 (-110)
U 237 (-110)
|
|
Oct 22, 2025 9:10PM EDT
Los Angeles Clippers
Utah Jazz
10/22/25 9:10PM
Clippers
Jazz
|
–
–
|
-375
+300
|
-9 (-110)
+9 (-110)
|
O 227 (-110)
U 227 (-110)
|
|
Oct 22, 2025 9:40PM EDT
San Antonio Spurs
Dallas Mavericks
10/22/25 9:40PM
Spurs
Mavericks
|
–
–
|
+120
-145
|
+3 (-115)
-3 (-105)
|
O 226.5 (+100)
U 226.5 (-120)
|
|
Oct 22, 2025 10:10PM EDT
Sacramento Kings
Phoenix Suns
10/22/25 10:10PM
Kings
Suns
|
–
–
|
+140
-170
|
+3.5 (-110)
-3.5 (-110)
|
O 227.5 (-110)
U 227.5 (-110)
|
|
Oct 22, 2025 10:10PM EDT
Minnesota Timberwolves
Portland Trail Blazers
10/22/25 10:10PM
Timberwolves
Trail Blazers
|
–
–
|
-170
+140
|
-3.5 (-110)
+3.5 (-110)
|
O 219.5 (-110)
U 219.5 (-110)
|
|
Oct 23, 2025 7:40PM EDT
Oklahoma City Thunder
Indiana Pacers
10/23/25 7:40PM
Thunder
Pacers
|
–
–
|
-325
+250
|
-7.5 (-110)
+7.5 (-110)
|
O 227 (-110)
U 227 (-110)
|
|
Oct 23, 2025 10:10PM EDT
Denver Nuggets
Golden State Warriors
10/23/25 10:10PM
Nuggets
Warriors
|
–
–
|
-115
-105
|
+1 (-115)
-1 (-105)
|
O 233.5 (-110)
U 233.5 (-110)
|
NBA Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Indiana Pacers vs. New York Knicks on May 21, 2025 at Madison Square Garden.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our NBA odds pages, and compare prices before you place a bet.
![]() |
LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
IND@OKC | PASCAL SIAKAM OVER 2.5 PERSONAL FOULS | 54.20% | 4 | WIN |
IND@OKC | IND +10 | 54.00% | 3 | WIN |
IND@OKC | BENNEDICT MATHURIN OVER 2.5 FREE THROW ATT | 54.90% | 4 | WIN |
NY@IND | MYLES TURNER OVER 6 REBOUNDS + ASSTS | 54.40% | 4 | LOSS |
IND@NY | IND +5 | 55.60% | 5 | LOSS |
NY@IND | JALEN BRUNSON UNDER 22 FIELD GOAL ATT | 54.70% | 4 | WIN |
OKC@MIN | RUDY GOBERT OVER 1.5 FREE THROWS MADE | 54.00% | 4 | WIN |
OKC@MIN | OKC -2.5 | 56.70% | 6 | LOSS |
NY@IND | KARL ANTHONY TOWNS OVER 32.5 POINTS + REBOUNDS | 54.00% | 4 | WIN |
OKC@MIN | NAZ REID OVER 9.0 FIELD GOAL ATT | 54.60% | 4 | LOSS |
IND@NY | MYLES TURNER OVER 5 MADE FIELD GOALS | 53.60% | 3 | WIN |
IND@NY | NY -5.5 | 55.00% | 4 | LOSS |
MIN@OKC | ISAIAH HARTENSTEIN UNDER 7.5 REBOUNDS | 53.00% | 3 | LOSS |
MIN@OKC | MIN +7.5 | 54.70% | 4 | LOSS |
IND@NY | TYRESE HALIBURTON ASSTS - UNDER 8.5 | 54.10% | 4 | LOSS |
IND@NY | IND +4.5 | 54.80% | 4 | WIN |
MIN@OKC | ALEX CARUSO UNDER 2.5 ASSTS | 54.10% | 4 | WIN |
DEN@OKC | MICHAEL PORTER UNDER 7.5 REBS + AST | 54.80% | 4 | WIN |
BOS@NY | NY -2.5 | 55.60% | 5 | WIN |
GS@MIN | DONTE DIVINCENZO OVER 1.5 TURNOVERS | 54.80% | 4 | LOSS |
GS@MIN | GS +10.5 | 54.70% | 4 | LOSS |
DEN@OKC | NIKOLA JOKIC UNDER 22.5 REBOUNDS + ASSTS | 54.00% | 4 | WIN |
MIN@GS | JIMMY BUTLER UNDER 33.5 POINTS + REBOUNDS | 54.50% | 4 | WIN |
BOS@NY | BOS -5.5 | 54.70% | 4 | WIN |
OKC@DEN | OKC -5 | 55.70% | 5 | LOSS |
DEN@OKC | SHAI GILGEOUS-ALEXANDER UNDER 12.5 REBOUNDS + ASSTS | 54.20% | 4 | WIN |
IND@CLE | IND +8 | 54.00% | 3 | WIN |
GS@MIN | ANTHONY EDWARDS UNDER 40.5 PTS+REB+AST | 54.00% | 4 | WIN |
GS@MIN | MIN -6.5 | 54.40% | 4 | LOSS |
DEN@OKC | NIKOLA JOKIC UNDER 36.5 POINTS + ASSTS | 53.20% | 3 | LOSS |
IND@CLE | IND +8.5 | 55.70% | 5 | WIN |
HOU@GS | GS -5 | 53.70% | 3 | LOSS |
HOU@GS | BRANDIN PODZIEMSKI UNDER 5.5 REBOUNDS | 54.10% | 4 | LOSS |
DEN@LAC | MICHAEL PORTER UNDER 7.5 REBS + AST | 53.20% | 3 | WIN |
DEN@LAC | UNDER 212.5 | 54.00% | 3 | LOSS |
MIN@LAL | MIN +6 | 53.80% | 3 | WIN |
MIN@LAL | NAZ REID OVER 1.5 ASSTS | 54.80% | 4 | WIN |
LAC@DEN | IVICA ZUBAC OVER 1.5 TURNOVERS | 53.50% | 3 | LOSS |
DET@NY | DET +5.5 | 53.90% | 3 | WIN |
CLE@MIA | EVAN MOBLEY UNDER 29.5 PTS+REB+AST | 53.90% | 3 | WIN |
BOS@ORL | KRISTAPS PORZINGIS UNDER 8.5 REBOUNDS + ASSTS | 53.10% | 3 | WIN |
HOU@GS | GS -3 | 53.70% | 3 | WIN |
HOU@GS | JALEN GREEN OVER 2.5 TURNOVERS | 54.40% | 4 | LOSS |
LAL@MIN | LEBRON JAMES UNDER 31.5 POINTS + REBOUNDS | 54.50% | 4 | LOSS |
BOS@ORL | BOS -3.5 | 54.70% | 4 | LOSS |
DEN@LAC | BOGDAN BOGDANOVIC OVER 2.5 THREE POINTERS ATTEMPTED | 53.60% | 3 | LOSS |
GS@HOU | JALEN GREEN UNDER 3.5 FREE THROWS MADE | 54.40% | 4 | LOSS |
ORL@BOS | ORL +10.5 | 54.70% | 4 | WIN |
MEM@OKC | ISAIAH HARTENSTEIN OVER 19.5 PTS + REB | 53.80% | 3 | LOSS |
MEM@OKC | OKC -14.5 | 54.80% | 4 | WIN |
LAC@DEN | IVICA ZUBAC OVER 3.5 OFFENSIVE REBOUNDS | 53.30% | 3 | LOSS |