Celtics vs Knicks Prediction — AI Finds CAN'T MISS NBA Lines & Props (May 16)

Updated: 2025-05-14T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Boston Celtics and New York Knicks are set to clash in Game 6 of their Eastern Conference Semifinal series on May 16, 2025, at Madison Square Garden. The Knicks lead the series 3-2 and aim to close it out at home, while the Celtics look to force a decisive Game 7.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: May 16, 2025

Start Time: 8:00 PM EST​

Venue: Madison Square Garden​

Knicks Record: (51-31)

Celtics Record: (61-21)

OPENING ODDS

BOS Moneyline: +116

NY Moneyline: -138

BOS Spread: +2.5

NY Spread: -2.5

Over/Under: 209.5

BOS
Betting Trends

  • The Boston Celtics have struggled against the spread (ATS) recently, with a 1-4 record in their last five games.

NY
Betting Trends

  • The New York Knicks have been solid ATS, boasting a 4-1 record in their last five games.

MATCHUP TRENDS

  • In the current playoff series, the Knicks have covered the spread in three of the five games, indicating their strong performance relative to expectations.

BOS vs. NY
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: K. Towns over 33.5 PTS+REB+AST.

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Boston vs New York Prediction & Odds:
Free NBA Betting Insights for 5/16/25

The Boston Celtics and New York Knicks are set to face off in a high-stakes Game 6 of their Eastern Conference Semifinal series on May 16, 2025, at Madison Square Garden, with the Knicks holding a 3-2 series lead and looking to punch their ticket to the Conference Finals for the first time in over two decades. The Celtics, who finished the regular season with the NBA’s best record at 61-21, now find themselves one loss away from elimination after dropping Game 5 at home in a hard-fought 104-98 contest that underscored their recent struggles with offensive execution and defensive adjustments. Despite boasting a dynamic duo in Jayson Tatum and Jaylen Brown, Boston has been unable to consistently solve the Knicks’ tenacious defense, and their dependence on perimeter shooting has led to cold stretches that New York has capitalized on to shift momentum. Jalen Brunson has been the difference-maker in the series, orchestrating the Knicks’ offense with poise and precision, getting into the paint at will, and exploiting mismatches, while Karl-Anthony Towns has stretched Boston’s defense by knocking down threes and punishing switches in the post. The Knicks have also received valuable contributions from OG Anunoby and Mikal Bridges, both of whom have played key roles in limiting Boston’s wing production and forcing turnovers with suffocating perimeter defense.

On the other end, the Celtics have struggled to slow New York’s interior scoring, with Mitchell Robinson and Isaiah Hartenstein crashing the glass and generating second-chance points that have swung multiple games in the series. Boston’s path to forcing a Game 7 hinges on their ability to clean up their offensive sets, limit turnovers, and get more efficient shot-making from Tatum, who has been forced into difficult looks due to New York’s defensive coverage. Joe Mazzulla’s offense, which thrived in the regular season by spreading the floor and launching threes, has sputtered under playoff pressure, particularly when their ball movement stalls and they settle for contested jumpers late in the shot clock. Defensively, the Celtics will need to contain Brunson’s dribble penetration and do a better job of rotating on pick-and-roll actions that have consistently pulled their bigs away from the rim. For the Knicks, playing at home in Game 6 presents a prime opportunity to close out a heavyweight series and avoid a return to Boston for a win-or-go-home Game 7. Thibodeau will continue to lean on his defensive foundation, trusting Brunson to control tempo, while Towns and the supporting cast provide scoring support in timely moments. The Garden crowd is sure to bring playoff energy, and if the Knicks can harness that intensity, maintain their defensive edge, and limit Boston’s second-chance opportunities, they’ll be in a strong position to end the series. This Game 6 represents a defining moment for both teams: for the Knicks, it’s a chance to validate their playoff toughness and advance as legitimate title contenders; for the Celtics, it’s an opportunity to remind the league why they were the top seed, but only if their stars rise to the occasion and their role players deliver in one of the league’s toughest environments.

Boston Celtics NBA Preview

The Boston Celtics head into Game 6 of their Eastern Conference Semifinal series against the New York Knicks on May 16, 2025, with the season on the line and their championship ambitions hanging by a thread after falling behind 3-2 in a series that has exposed the inconsistencies and vulnerabilities that were masked during a dominant regular season. Despite finishing with a league-best 61-21 record, the Celtics now face a hostile Madison Square Garden crowd and a Knicks team that has found its defensive identity at the perfect time, holding Boston to under 100 points in two of the last three games. Jayson Tatum and Jaylen Brown, the core of Boston’s offensive attack, have delivered scoring in stretches, but their efficiency has dropped significantly under constant pressure from OG Anunoby and Mikal Bridges, whose physical defense and ability to force contested shots have disrupted Boston’s rhythm and forced them into hero-ball sequences late in the shot clock. Boston’s three-point shooting, which carried them through much of the regular season, has gone cold at the worst possible time, and the team’s overreliance on perimeter scoring has resulted in scoring droughts that have allowed New York to control the pace and momentum of the series. Defensively, the Celtics have not had an answer for Jalen Brunson, who has carved them up with pick-and-roll actions, mid-range jumpers, and timely drives that have either resulted in buckets or drawn help, creating open looks for Towns, Bridges, and New York’s bench.

Boston’s interior defense has also been shaky, with the absence of consistent rim protection allowing Mitchell Robinson and Isaiah Hartenstein to feast on second-chance opportunities and disrupt any rhythm the Celtics try to build on the defensive glass. While Derrick White and Jrue Holiday have made strong individual defensive efforts, the lack of cohesion in Boston’s help rotations and the inability to defend without fouling has been costly in close games. Head coach Joe Mazzulla has tried to make in-series adjustments—most notably switching coverages and staggering Tatum and Brown’s minutes more—but the Celtics have yet to find a sustained rhythm against New York’s physical, grinding style of play. In order to force a Game 7, Boston must not only shoot better from deep but also make a concerted effort to attack the rim, draw fouls, and reestablish a physical tone early in the game to prevent the Knicks from setting the pace and engaging the MSG crowd. For the Celtics, Game 6 is not just about extending their season—it’s a test of character for a team that has faced repeated playoff heartbreaks over the last several years. If Tatum and Brown can play with urgency and poise, if the bench can provide meaningful minutes, and if Boston can finally win the hustle categories that the Knicks have dominated, they still have the talent to turn this series around. But if they again fall into the same trap of rushed possessions, soft interior defense, and poor late-game execution, their 2025 playoff run will end short of expectations, and questions about this team’s ability to close in high-pressure moments will resurface louder than ever. Game 6 is the ultimate gut check for a Celtics team that came into the season with title-or-bust expectations—and now has to prove it in the toughest road environment in the NBA.

The Boston Celtics and New York Knicks are set to clash in Game 6 of their Eastern Conference Semifinal series on May 16, 2025, at Madison Square Garden. The Knicks lead the series 3-2 and aim to close it out at home, while the Celtics look to force a decisive Game 7. Boston vs New York AI Prediction: Free NBA Betting Insights for May 16. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

New York Knicks NBA Preview

The New York Knicks return to Madison Square Garden for Game 6 of their Eastern Conference Semifinal series on May 16, 2025, with a 3-2 lead over the Boston Celtics and a golden opportunity to close out one of the NBA’s top title contenders in front of a raucous home crowd. Under the steady leadership of Tom Thibodeau, the Knicks have methodically taken control of the series after falling behind 2-1, winning two straight games with a formula built on physical defense, half-court execution, and elite clutch play from Jalen Brunson, who has outdueled Boston’s All-Stars down the stretch in every one of New York’s victories. Brunson’s poise, ability to control the tempo, and shot creation in tight spaces have been the cornerstone of the Knicks’ offense, while Karl-Anthony Towns has provided versatility by scoring both inside and from the perimeter, forcing Boston’s bigs to defend away from the rim and creating crucial spacing for New York’s attack. OG Anunoby and Mikal Bridges have been instrumental in slowing down Jayson Tatum and Jaylen Brown, using length, anticipation, and relentless pressure to contest shots, force turnovers, and disrupt Boston’s rhythm offensively—an edge that has fueled New York’s momentum and turned defense into offense consistently throughout the series. The Knicks’ role players have risen to the moment as well, with key contributions from Isaiah Hartenstein, Donte DiVincenzo, and Josh Hart helping New York outplay Boston’s bench in terms of energy, rebounding, and hustle. Hartenstein’s rebounding and physicality have helped control the paint, while DiVincenzo’s timely shot-making and Hart’s all-around grit have allowed the Knicks to win the effort categories that make the difference in playoff basketball. Thibodeau has masterfully staggered rotations and kept fresh legs on the court without sacrificing defensive integrity, maintaining pressure on Boston throughout the game and denying the Celtics the rhythm they thrived on during the regular season. New York’s success at home has been no fluke—the team is feeding off the energy of the MSG crowd, who have transformed each home playoff game into an electric, playoff-hardened atmosphere that’s disrupted visiting stars and galvanized the Knicks’ physical style of play. With Boston reeling and struggling to generate offense outside of isolation sets and long-distance shooting, the Knicks are poised to seize control early in Game 6 and apply pressure throughout, forcing the Celtics to adapt to their game rather than dictate their own. If the Knicks continue to defend with the same intensity, execute offensively through Brunson and Towns, and dominate the intangibles—second-chance points, loose balls, and transition defense—they have every tool needed to close out this series without a return trip to Boston. The home crowd will be a factor from the opening tip, and New York’s ability to stay composed, respond to runs, and stick to their blueprint will be key to finishing the job. Game 6 offers the franchise a chance to make its first Conference Finals appearance in over two decades and signal a legitimate return to contention in the Eastern Conference—an outcome that now feels within reach, provided the Knicks play their game and capitalize on the opportunity in front of them.

Boston vs. New York Prop Picks (AI)

AI algorithm Remi is pouring through tons of datapoints on each player. In fact, anytime the Celtics and Knicks play there’s always several intriguing angles to key in on. Not to mention games played at Madison Square Garden in May rarely follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: K. Towns over 33.5 PTS+REB+AST.

Boston vs. New York Prediction (AI)

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Remi, our AI sports wizard, has been pouring over mountains of data from every facet between the Celtics and Knicks and using recursive machine learning and cutting-edge AI to crunch the data to a single cover probability.

Interestingly enough, the data has been most keyed in on the linear correlation of emphasis emotional bettors tend to put on Boston’s strength factors between a Celtics team going up against a possibly deflated Knicks team. Trends look to say the true game analytics appear to reflect a strong lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our NBA AI picks for FREE now.

Below is our current AI Boston vs New York picks, computer picks Celtics vs Knicks, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
NBA 11/8 POR@MIA UNLOCK THIS PICK 7 VAULT v3 Locked VAULT v3
NBA 11/8 LAL@ATL UNLOCK THIS PICK 6 VAULT v2 Locked VAULT v2
NBA 11/8 IND@DEN UNLOCK THIS PICK 0 INTEL Locked INTEL
NBA 11/8 CHI@CLE UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NBA schedule.

Celtics Betting Trends

The Boston Celtics have struggled against the spread (ATS) recently, with a 1-4 record in their last five games.

Knicks Betting Trends

The New York Knicks have been solid ATS, boasting a 4-1 record in their last five games.

Celtics vs. Knicks Matchup Trends

In the current playoff series, the Knicks have covered the spread in three of the five games, indicating their strong performance relative to expectations.

Boston vs. New York Game Info

Boston vs New York starts on May 16, 2025 at 8:00 PM EST.

Venue: Madison Square Garden.

Spread: New York -2.5
Moneyline: Boston +116, New York -138
Over/Under: 209.5

Boston: (61-21)  |  New York: (51-31)

Remi's searched hard and found the best prop for this matchup: K. Towns over 33.5 PTS+REB+AST.. Prices move—always shop for the best number.

In the current playoff series, the Knicks have covered the spread in three of the five games, indicating their strong performance relative to expectations.

BOS trend: The Boston Celtics have struggled against the spread (ATS) recently, with a 1-4 record in their last five games.

NY trend: The New York Knicks have been solid ATS, boasting a 4-1 record in their last five games.

See our latest NBA picks and odds pages for 2025 to compare prices before you bet.

Boston vs. New York Odds

AI algorithm Remi is pouring through mountains of stats on each player. In fact, anytime the Boston vs New York trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme temps almost always follow normal, predictable betting trends.

Boston vs New York Opening Odds

BOS Moneyline: +116
NY Moneyline: -138
BOS Spread: +2.5
NY Spread: -2.5
Over/Under: 209.5

Boston vs New York Live Odds

Games PTS ML SPR O/U
Nov 9, 2025 3:30PM EST
Houston Rockets
Milwaukee Bucks
11/9/25 3:30PM
Rockets
Bucks
-168
+140
-4 (-108)
+4 (-112)
O 232.5 (-108)
U 232.5 (-112)
Nov 9, 2025 6:00PM EST
Brooklyn Nets
New York Knicks
11/9/25 6PM
Nets
Knicks
+750
-1200
+16.5 (-114)
-16.5 (-106)
O 228.5 (-110)
U 228.5 (-110)
Nov 9, 2025 6:10PM EST
Oklahoma City Thunder
Memphis Grizzlies
11/9/25 6:10PM
Thunder
Grizzlies
-560
+420
-10.5 (-112)
+10.5 (-108)
O 233.5 (-110)
U 233.5 (-110)
Nov 9, 2025 6:10PM EST
Boston Celtics
Orlando Magic
11/9/25 6:10PM
Celtics
Magic
+126
-148
+3 (-110)
-3 (-110)
O 226.5 (-108)
U 226.5 (-112)
Nov 9, 2025 7:30PM EST
Detroit Pistons
Philadelphia 76ers
11/9/25 7:30PM
Pistons
76ers
-164
+138
-4 (-110)
+4 (-110)
O 232.5 (-110)
U 232.5 (-110)
Nov 9, 2025 8:40PM EST
Indiana Pacers
Golden State Warriors
11/9/25 8:40PM
Pacers
Warriors
+490
-670
+12.5 (-110)
-12.5 (-110)
O 227.5 (-110)
U 227.5 (-110)
Nov 9, 2025 9:10PM EST
Minnesota Timberwolves
Sacramento Kings
11/9/25 9:10PM
Timberwolves
Kings
-230
+190
-5.5 (-110)
+5.5 (-110)
O 234.5 (-112)
U 234.5 (-108)
Dec 25, 2025 12:00PM EST
Cleveland Cavaliers
New York Knicks
12/25/25 12PM
Cavaliers
Knicks
+117
-143
+2.5 (-113)
-2.5 (-113)
O 229.5 (-113)
U 229.5 (-113)
Dec 25, 2025 5:00PM EST
Dallas Mavericks
Golden State Warriors
12/25/25 5PM
Mavericks
Warriors
+150
-195
+4.5 (-112)
-4.5 (-114)
O 227 (-115)
U 227 (-110)
Dec 25, 2025 10:30PM EST
Minnesota Timberwolves
Denver Nuggets
12/25/25 10:30PM
Timberwolves
Nuggets
+175
-220
+5 (-109)
-5 (-117)
O 229.5 (-112)
U 229.5 (-114)

NBA Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Boston Celtics vs. New York Knicks on May 16, 2025 at Madison Square Garden.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our NBA odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
DAL@MEM MEM -4 56.3% 6 WIN
TOR@ATL TOR +118 48.0% 3 WIN
CHA@MIA OVER 235.5 54.3% 3 LOSS
LAC@PHX PHX -135 58.9% 7 WIN
PHI@CLE PHI +10.5 53.3% 3 LOSS
MIA@DEN MIA +9.5 53.7% 3 LOSS
OKC@POR POR +4.5 52.9% 3 WIN
HOU@MEM MEM +8.5 54.7% 4 LOSS
UTA@DET UTA +10 56.8% 6 LOSS
NO@DAL TREY MURPHY III OVER 25.5 PTS & REB 55.5% 5 LOSS
ORL@ATL ORL -3.5 56.5% 6 LOSS
MIL@TOR MIL +3.5 56.5% 4 LOSS
PHX@GS STEPH CURRY UNDER 4.5 THREE PTRS MADE 53.3% 3 LOSS
OKC@LAC JAMES HARDEN OVER 12.5 REBOUNDS + ASSTS 56.1% 6 LOSS
LAL@POR POR -2.5 54.7% 4 LOSS
SA@PHX SA -5.5 56.6% 6 LOSS
ORL@WAS WAS +9 54.2% 4 LOSS
DAL@DET DAL +8 58.7% 8 LOSS
NY@CHI NY -4.5 54.7% 4 LOSS
BOS@PHI BOS +1.5 54.6% 4 WIN
TOR@CLE TOR +6 56.2% 6 WIN
DEN@POR JERAMI GRANT OVER 1.5 TURNOVERS 56.6% 6 WIN
WAS@OKC WAS +15.5 54.9% 4 LOSS
NO@DEN DEN -12.5 53.6% 3 WIN
NO@DEN NIKOLA JOKIC OVER 26.5 POINTS 56.6% 6 LOSS
SAC@OKC SAC +10 54.7% 4 WIN
NY@MIL MIL +3 56.6% 6 WIN
LAC@GS GS +2.5 56.8% 6 WIN
LAC@GS BRANDIN PODZIEMSKI UNDER 1.5 THREE POINTERS MADE 55.5% 5 LOSS
CLE@DET DET +2.5 53.5% 3 LOSS
ORL@PHI ORL -5 54.7% 4 LOSS
OKC@DAL DAL +9 66.4% 6 WIN
BOS@NO NO +2 55.6% 5 LOSS
BKN@HOU BKN +16.5 57.0% 7 LOSS
BOS@NO TREY MURPHY III UNDER 25.5 PTS + REB 54.4% 4 WIN
MIL@CLE MIL +6.5 56.1% 6 WIN
POR@LAC POR +8.5 56.5% 6 WIN
ATL@ORL ATL +5 54.6% 4 WIN
WAS@DAL WAS +10 55.3% 5 WIN
PHX@LAC IVICA ZUBAC OVER 6.5 MADE FIELD GOALS 55.5% 5 LOSS
OKC@IND IND +8 56.5% 6 WIN
CLE@NY CLE -116 55.0% 4 LOSS
LAC@UTA UTA +9.5 54.1% 4 WIN
WAS@MIL KYLE KUZMA OVER 1.5 ASSTS 55.5% 5 WIN
HOU@OKC HOU +6.5 54.8% 4 WIN
GS@LAL STEPHEN CURRY UNDER 2.5 TURNOVERS 54.4 4 WIN
IND@OKC SHAI GILGEOUS-ALEXANDER OVER 1.5 STEALS 54.90% 4 LOSS
IND@OKC JALEN WILLIAMS OVER 0.5 1Q REBOUNDS 55.70% 5 WIN
OKC@IND TJ MCCONNELL UNDER 7.5 TWO POINT ATT 55.70% 5 LOSS
IND@OKC CHET HOLMGREN OVER 1.5 SHOTS BLOCKED 53.40% 3 WIN
OKC@IND TJ MCCONNELL OVER 1.5 TURNOVERS 53.00% 3 LOSS