Pacers vs. Cavaliers
Prediction, Odds & Props
May 06 | NBA AI Picks
Updated: 2025-05-04T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Indiana Pacers and Cleveland Cavaliers are set to clash in Game 2 of their Eastern Conference Semifinal series on Tuesday, May 6, 2025, at Rocket Mortgage FieldHouse in Cleveland. The Pacers currently lead the series 1-0 after a surprising 121-112 victory in Game 1, where they outshot the Cavaliers from beyond the arc and capitalized on Cleveland’s shooting woes.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: May 06, 2025
Start Time: 7:00 PM EST
Venue: Rocket Arena
Cavaliers Record: (64-18)
Pacers Record: (50-32)
OPENING ODDS
IND Moneyline: +345
CLE Moneyline: -446
IND Spread: +9.5
CLE Spread: -9.5
Over/Under: 229.5
IND
Betting Trends
- The Indiana Pacers have a 50-26-2 record against the spread (ATS) this season, covering the spread in approximately 65.8% of their games.
CLE
Betting Trends
- The Cleveland Cavaliers have a 56-28-2 ATS record this season, covering the spread in about 66.7% of their games.
MATCHUP TRENDS
- In their last 10 games, the Pacers have covered the spread in 8 games, demonstrating strong performance against the spread leading into this series.
IND vs. CLE
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: D. Garland over 26.5 PTS+REB+AST.
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Indiana vs Cleveland Prediction & Odds:
Free NBA Betting Insights for 5/6/25
Defensively, Cleveland’s signature toughness and communication were missing, as they were often late rotating to the perimeter and failed to contest Indiana’s rhythm shooters, a surprising development given the Cavaliers’ second-ranked defensive efficiency during the regular season. Looking ahead to Game 2, Cleveland must regroup and bring greater urgency to their defensive sets, potentially adjusting their coverages to limit Haliburton’s playmaking while closing out more aggressively on Indiana’s perimeter threats. A potential return from Garland could be the spark they need, rebalancing the offense and giving the Cavaliers more lineup flexibility to counter Indiana’s pace and movement. For the Pacers, the challenge will be sustaining their offensive execution while preparing for a much more desperate and likely more physical Cleveland team, but if they can continue to spread the floor, hit timely threes, and execute in transition, they have a real chance to head back to Indiana with a commanding 2-0 series lead. The strategic chess match between Carlisle and Kenny Atkinson now takes center stage, as both coaches look to exploit matchup weaknesses and adjust rotations, knowing that Game 2 could swing the trajectory of what has quickly become one of the most intriguing series of the postseason.
The 2024-25 Indiana Pacers have proven they can compete with any team, and the Eastern Conference semifinals will now run through Indianapolis thanks to the attributes that have fueled the team since last year’s deep playoff run.
— Indiana Pacers (@Pacers) May 5, 2025
📝 by @JordanAMorey ⬇️
https://t.co/3X8B3uuETT
Indiana Pacers NBA Preview
The Indiana Pacers come into Game 2 of their Eastern Conference Semifinal series against the Cleveland Cavaliers with the momentum and confidence of a team that not only won on the road but did so with style and precision, executing a balanced offensive attack that overwhelmed the NBA’s top-seeded team in a 121-112 Game 1 victory. With a 50-26-2 record against the spread this season and covers in eight of their last ten games, the Pacers have become one of the most consistent and resilient teams in the league, and their Game 1 performance only reinforced their identity as a dangerous, well-coached group that thrives on offensive rhythm, ball movement, and smart shot selection. Tyrese Haliburton was once again the orchestrator, delivering 22 points and 12 assists with surgical efficiency, controlling the tempo and exploiting Cleveland’s slower defensive rotations with high-IQ pick-and-rolls and timely passes to shooters in space. Andrew Nembhard was the breakout star, pouring in 23 points on 5-of-6 shooting from deep, and his ability to stretch the floor, defend multiple positions, and provide secondary playmaking was pivotal in taking pressure off Haliburton and opening up the Cavaliers’ defense. Veterans Pascal Siakam and Myles Turner added physicality and versatility on both ends of the floor, with Siakam scoring in transition and in the midrange, while Turner held his own against Cleveland’s bigs by contesting shots at the rim and cleaning the glass.
Head coach Rick Carlisle’s offensive system, built on spacing, movement, and selflessness, allowed Indiana to pick apart Cleveland’s usually elite defense by forcing them into tough closeouts and exploiting lapses in communication, and that discipline will be crucial again in Game 2, especially with the Cavaliers likely to respond with greater intensity. On the defensive end, the Pacers were far from perfect but timely with their rotations and physical in their contests, especially on Cleveland’s shooters, and they consistently denied easy looks around the arc while protecting the paint just enough to frustrate Donovan Mitchell, who, despite scoring 33 points, went 1-for-11 from three. Indiana’s ability to take Cleveland out of their comfort zone, force isolation-heavy possessions, and capitalize on their own efficient shooting was the formula for Game 1 success—and maintaining that composure will be vital in Game 2 as the Cavaliers adjust and push back with urgency. The Pacers understand that this is a golden opportunity to take a commanding 2-0 lead back to Indiana, and with their offensive chemistry clicking, their role players stepping up, and Haliburton firmly in control of the tempo, they appear fully prepared to meet the moment. Whether they can replicate their sharp shooting and disciplined execution under heightened pressure will determine if their Game 1 win was an outlier or the beginning of a legitimate run toward the Eastern Conference Finals, but one thing is certain—this Indiana team is fearless, fluid, and fully capable of rewriting expectations with every possession.

Credit: USA TODAY/IMAGN
Cleveland Cavaliers NBA Preview
The Cleveland Cavaliers return to Rocket Mortgage FieldHouse for Game 2 of the Eastern Conference Semifinals with urgency and determination after a disappointing 121-112 loss to the Indiana Pacers in Game 1, a game in which their strengths unraveled under pressure and their normally disciplined defense failed to contain one of the NBA’s most fluid offensive teams. Despite finishing the regular season with a league-best 64-18 record and boasting one of the top defenses in the league, Cleveland looked out of sync defensively, allowing Indiana to shoot a blistering 53% from three-point range and break them down with constant ball movement and off-ball activity. Donovan Mitchell led the Cavaliers offensively with 33 points, but his inefficiency from deep—just 1-for-11 from beyond the arc—highlighted how much pressure he was under without All-Star guard Darius Garland, who missed Game 1 due to injury and whose absence severely limited the team’s offensive flexibility. Evan Mobley played well with 20 points and 10 rebounds, showing touch in the mid-post and effort defensively, but Jarrett Allen was largely neutralized by Indiana’s spacing and Turner’s ability to pull him away from the basket, which opened up cutting lanes and offensive rebounding opportunities for the Pacers. Without Garland to help create and spread the floor, the Cavaliers’ offense leaned heavily on Mitchell’s isolation scoring and Mobley’s interior touch, both of which faltered against Indiana’s timely double teams and help defense.
Defensively, the Cavaliers struggled to track shooters and failed to communicate effectively on switches, allowing Andrew Nembhard to explode for 23 points and Tyrese Haliburton to orchestrate clean looks with ease. Head coach Kenny Atkinson will need to tighten up the defensive rotations and potentially mix in more aggressive on-ball pressure or switch-heavy schemes to keep Indiana’s guards from getting comfortable early, while on offense, more ball movement, screen action, and transition scoring will be needed to relieve the stagnation that plagued them in Game 1. If Garland is able to return for Game 2, his playmaking and ability to collapse the defense will be a welcome addition that could completely shift the tone, but even without him, Cleveland’s deep roster, including Caris LeVert, Max Strus, and Georges Niang, must step up and hit perimeter shots to keep pace with Indiana’s spacing. Playing in front of their home crowd, the Cavaliers have an opportunity to reassert their identity as a physical, disciplined defensive team that dictates tempo and forces opponents to grind for every look, and they will need to do so with increased urgency and focus to avoid falling into a daunting 0-2 hole. For Cleveland, this game is about responding to adversity, restoring rhythm on both ends, and proving that their dominance all season wasn’t just statistical—it was real, and it’s ready to surface when the stakes are highest.
Final. @betwayusa | #LetEmKnow pic.twitter.com/AtdeV28z2o
— Cleveland Cavaliers (@cavs) May 5, 2025
Indiana vs. Cleveland Prop Picks (AI)
Indiana vs. Cleveland Prediction (AI)

Remi, our AI sports wizard, has been pouring over exorbitant amounts of data from every simulation between the Pacers and Cavaliers and using recursive machine learning and kick-ass AI to boil down the data to a single cover probability.
Interestingly enough, the data has been most focused on the trending factor human bettors tend to put on player performance factors between a Pacers team going up against a possibly rested Cavaliers team. It appears the true game analytics appear to reflect a moderate lean against one Vegas line specifically.
Unlock this in-depth AI prediction and all of our NBA AI picks for FREE now.
Below is our current AI Indiana vs Cleveland picks, computer picks Pacers vs Cavaliers, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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ACTIVE PICKS LOCKED - SEE NOW |
These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NBA schedule.
Pacers Betting Trends
The Indiana Pacers have a 50-26-2 record against the spread (ATS) this season, covering the spread in approximately 65.8% of their games.
Cavaliers Betting Trends
The Cleveland Cavaliers have a 56-28-2 ATS record this season, covering the spread in about 66.7% of their games.
Pacers vs. Cavaliers Matchup Trends
In their last 10 games, the Pacers have covered the spread in 8 games, demonstrating strong performance against the spread leading into this series.
Indiana vs. Cleveland Game Info
What time does Indiana vs Cleveland start on May 06, 2025?
Indiana vs Cleveland starts on May 06, 2025 at 7:00 PM EST.
Where is Indiana vs Cleveland being played?
Venue: Rocket Arena.
What are the opening odds for Indiana vs Cleveland?
Spread: Cleveland -9.5
Moneyline: Indiana +345, Cleveland -446
Over/Under: 229.5
What are the records for Indiana vs Cleveland?
Indiana: (50-32) | Cleveland: (64-18)
What is the AI best bet for Indiana vs Cleveland?
Remi's searched hard and found the best prop for this matchup: D. Garland over 26.5 PTS+REB+AST.. Prices move—always shop for the best number.
What are Indiana vs Cleveland trending bets?
In their last 10 games, the Pacers have covered the spread in 8 games, demonstrating strong performance against the spread leading into this series.
What are Indiana trending bets?
IND trend: The Indiana Pacers have a 50-26-2 record against the spread (ATS) this season, covering the spread in approximately 65.8% of their games.
What are Cleveland trending bets?
CLE trend: The Cleveland Cavaliers have a 56-28-2 ATS record this season, covering the spread in about 66.7% of their games.
Where can I find AI Picks for Indiana vs Cleveland?
See our latest NBA picks and odds pages for 2025 to compare prices before you bet.
Indiana vs. Cleveland Odds
Remi is pouring through tons of data points on each player. In fact, anytime the Indiana vs Cleveland trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme travel distance seemingly never follow normal, predictable patterns.
Indiana vs Cleveland Opening Odds
IND Moneyline:
+345 CLE Moneyline: -446
IND Spread: +9.5
CLE Spread: -9.5
Over/Under: 229.5
Indiana vs Cleveland Live Odds
Games | PTS | ML | SPR | O/U | |
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Oct 21, 2025 7:30PM EDT
Houston Rockets
Oklahoma City Thunder
10/21/25 7:30PM
Rockets
Thunder
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–
–
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+230
-305
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+7.5 (-114)
-7.5 (-112)
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O 225.5 (-114)
U 225.5 (-112)
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Oct 21, 2025 10:00PM EDT
Golden State Warriors
Los Angeles Lakers
10/21/25 10PM
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Lakers
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–
–
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+135
-167
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+3.5 (-112)
-3.5 (-114)
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O 224.5 (-112)
U 224.5 (-114)
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Oct 22, 2025 7:10PM EDT
Brooklyn Nets
Charlotte Hornets
10/22/25 7:10PM
Nets
Hornets
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–
–
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+145
-182
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+4 (-115)
-4 (-110)
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O 221 (-113)
U 221 (-113)
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Oct 22, 2025 7:10PM EDT
Cleveland Cavaliers
New York Knicks
10/22/25 7:10PM
Cavaliers
Knicks
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–
–
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+145
-182
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+4 (-114)
-4 (-112)
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O 227.5 (-112)
U 227.5 (-114)
|
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Oct 22, 2025 7:10PM EDT
Miami Heat
Orlando Magic
10/22/25 7:10PM
Heat
Magic
|
–
–
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+240
-315
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+7.5 (-113)
-7.5 (-113)
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O 207 (-113)
U 207 (-112)
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Oct 22, 2025 7:40PM EDT
Philadelphia 76ers
Boston Celtics
10/22/25 7:40PM
76ers
Celtics
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–
–
|
+107
-132
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+2 (-110)
-2 (-115)
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O 221.5 (-115)
U 221.5 (-110)
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Oct 22, 2025 7:40PM EDT
Toronto Raptors
Atlanta Hawks
10/22/25 7:40PM
Raptors
Hawks
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–
–
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+190
-245
|
+6 (-113)
-6 (-112)
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O 236.5 (-114)
U 236.5 (-112)
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Oct 22, 2025 8:10PM EDT
Washington Wizards
Milwaukee Bucks
10/22/25 8:10PM
Wizards
Bucks
|
–
–
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+285
-385
|
+8.5 (-115)
-8.5 (-109)
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O 225 (-110)
U 225 (-115)
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Oct 22, 2025 8:10PM EDT
Detroit Pistons
Chicago Bulls
10/22/25 8:10PM
Pistons
Bulls
|
–
–
|
-132
+106
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-2 (-114)
+2 (-112)
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O 236.5 (-114)
U 236.5 (-112)
|
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Oct 22, 2025 8:10PM EDT
New Orleans Pelicans
Memphis Grizzlies
10/22/25 8:10PM
Pelicans
Grizzlies
|
–
–
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+150
-190
|
+4.5 (-112)
-4.5 (-113)
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O 238.5 (-113)
U 238.5 (-113)
|
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Oct 22, 2025 9:10PM EDT
Los Angeles Clippers
Utah Jazz
10/22/25 9:10PM
Clippers
Jazz
|
–
–
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-345
+260
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-8 (-113)
+8 (-112)
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O 227.5 (-112)
U 227.5 (-114)
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Oct 22, 2025 9:40PM EDT
San Antonio Spurs
Dallas Mavericks
10/22/25 9:40PM
Spurs
Mavericks
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–
–
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-113
-110
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-1 (-109)
+1 (-117)
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O 226.5 (-112)
U 226.5 (-113)
|
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Oct 22, 2025 10:10PM EDT
Sacramento Kings
Phoenix Suns
10/22/25 10:10PM
Kings
Suns
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–
–
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-103
-121
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+1.5 (-114)
-1.5 (-110)
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O 229.5 (-112)
U 229.5 (-114)
|
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Oct 22, 2025 10:10PM EDT
Minnesota Timberwolves
Portland Trail Blazers
10/22/25 10:10PM
Timberwolves
Trail Blazers
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–
–
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-143
+115
|
-2.5 (-114)
+2.5 (-112)
|
O 216 (-114)
U 216 (-112)
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Oct 23, 2025 7:40PM EDT
Oklahoma City Thunder
Indiana Pacers
10/23/25 7:40PM
Thunder
Pacers
|
–
–
|
-323
+240
|
-7.5 (-110)
+7.5 (-110)
|
O 226.5 (-110)
U 226.5 (-110)
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Oct 23, 2025 10:10PM EDT
Denver Nuggets
Golden State Warriors
10/23/25 10:10PM
Nuggets
Warriors
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–
–
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-109
-116
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+1 (-110)
-1 (-110)
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O 232.5 (-110)
U 232.5 (-110)
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NBA Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Indiana Pacers vs. Cleveland Cavaliers on May 06, 2025 at Rocket Arena.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our NBA odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
IND@OKC | PASCAL SIAKAM OVER 2.5 PERSONAL FOULS | 54.20% | 4 | WIN |
IND@OKC | IND +10 | 54.00% | 3 | WIN |
IND@OKC | BENNEDICT MATHURIN OVER 2.5 FREE THROW ATT | 54.90% | 4 | WIN |
NY@IND | MYLES TURNER OVER 6 REBOUNDS + ASSTS | 54.40% | 4 | LOSS |
IND@NY | IND +5 | 55.60% | 5 | LOSS |
NY@IND | JALEN BRUNSON UNDER 22 FIELD GOAL ATT | 54.70% | 4 | WIN |
OKC@MIN | RUDY GOBERT OVER 1.5 FREE THROWS MADE | 54.00% | 4 | WIN |
OKC@MIN | OKC -2.5 | 56.70% | 6 | LOSS |
NY@IND | KARL ANTHONY TOWNS OVER 32.5 POINTS + REBOUNDS | 54.00% | 4 | WIN |
OKC@MIN | NAZ REID OVER 9.0 FIELD GOAL ATT | 54.60% | 4 | LOSS |
IND@NY | MYLES TURNER OVER 5 MADE FIELD GOALS | 53.60% | 3 | WIN |
IND@NY | NY -5.5 | 55.00% | 4 | LOSS |
MIN@OKC | ISAIAH HARTENSTEIN UNDER 7.5 REBOUNDS | 53.00% | 3 | LOSS |
MIN@OKC | MIN +7.5 | 54.70% | 4 | LOSS |
IND@NY | TYRESE HALIBURTON ASSTS - UNDER 8.5 | 54.10% | 4 | LOSS |
IND@NY | IND +4.5 | 54.80% | 4 | WIN |
MIN@OKC | ALEX CARUSO UNDER 2.5 ASSTS | 54.10% | 4 | WIN |
DEN@OKC | MICHAEL PORTER UNDER 7.5 REBS + AST | 54.80% | 4 | WIN |
BOS@NY | NY -2.5 | 55.60% | 5 | WIN |
GS@MIN | DONTE DIVINCENZO OVER 1.5 TURNOVERS | 54.80% | 4 | LOSS |
GS@MIN | GS +10.5 | 54.70% | 4 | LOSS |
DEN@OKC | NIKOLA JOKIC UNDER 22.5 REBOUNDS + ASSTS | 54.00% | 4 | WIN |
MIN@GS | JIMMY BUTLER UNDER 33.5 POINTS + REBOUNDS | 54.50% | 4 | WIN |
BOS@NY | BOS -5.5 | 54.70% | 4 | WIN |
OKC@DEN | OKC -5 | 55.70% | 5 | LOSS |
DEN@OKC | SHAI GILGEOUS-ALEXANDER UNDER 12.5 REBOUNDS + ASSTS | 54.20% | 4 | WIN |
IND@CLE | IND +8 | 54.00% | 3 | WIN |
GS@MIN | ANTHONY EDWARDS UNDER 40.5 PTS+REB+AST | 54.00% | 4 | WIN |
GS@MIN | MIN -6.5 | 54.40% | 4 | LOSS |
DEN@OKC | NIKOLA JOKIC UNDER 36.5 POINTS + ASSTS | 53.20% | 3 | LOSS |
IND@CLE | IND +8.5 | 55.70% | 5 | WIN |
HOU@GS | GS -5 | 53.70% | 3 | LOSS |
HOU@GS | BRANDIN PODZIEMSKI UNDER 5.5 REBOUNDS | 54.10% | 4 | LOSS |
DEN@LAC | MICHAEL PORTER UNDER 7.5 REBS + AST | 53.20% | 3 | WIN |
DEN@LAC | UNDER 212.5 | 54.00% | 3 | LOSS |
MIN@LAL | MIN +6 | 53.80% | 3 | WIN |
MIN@LAL | NAZ REID OVER 1.5 ASSTS | 54.80% | 4 | WIN |
LAC@DEN | IVICA ZUBAC OVER 1.5 TURNOVERS | 53.50% | 3 | LOSS |
DET@NY | DET +5.5 | 53.90% | 3 | WIN |
CLE@MIA | EVAN MOBLEY UNDER 29.5 PTS+REB+AST | 53.90% | 3 | WIN |
BOS@ORL | KRISTAPS PORZINGIS UNDER 8.5 REBOUNDS + ASSTS | 53.10% | 3 | WIN |
HOU@GS | GS -3 | 53.70% | 3 | WIN |
HOU@GS | JALEN GREEN OVER 2.5 TURNOVERS | 54.40% | 4 | LOSS |
LAL@MIN | LEBRON JAMES UNDER 31.5 POINTS + REBOUNDS | 54.50% | 4 | LOSS |
BOS@ORL | BOS -3.5 | 54.70% | 4 | LOSS |
DEN@LAC | BOGDAN BOGDANOVIC OVER 2.5 THREE POINTERS ATTEMPTED | 53.60% | 3 | LOSS |
GS@HOU | JALEN GREEN UNDER 3.5 FREE THROWS MADE | 54.40% | 4 | LOSS |
ORL@BOS | ORL +10.5 | 54.70% | 4 | WIN |
MEM@OKC | ISAIAH HARTENSTEIN OVER 19.5 PTS + REB | 53.80% | 3 | LOSS |
MEM@OKC | OKC -14.5 | 54.80% | 4 | WIN |
LAC@DEN | IVICA ZUBAC OVER 3.5 OFFENSIVE REBOUNDS | 53.30% | 3 | LOSS |