Grizzlies vs Thunder Prediction — AI Finds CAN'T MISS NBA Lines & Props (Apr 22)

Updated: 2025-04-20T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Oklahoma City Thunder host the Memphis Grizzlies in Game 2 of their Western Conference first-round playoff series on April 22, 2025, at Paycom Center. The Thunder lead the series 1–0 after a commanding 125–104 victory in Game 1, showcasing their dominance as the top seed.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Apr 22, 2025

Start Time: 7:30 PM EST​

Venue: Paycom Center​

Thunder Record: (68-14)

Grizzlies Record: (48-34)

OPENING ODDS

MEM Moneyline: +721

OKC Moneyline: -1149

MEM Spread: +14.5

OKC Spread: -14.5

Over/Under: 229.5

MEM
Betting Trends

  • The Grizzlies have a 41–40–1 record against the spread (ATS) this season, covering 50.6% of their games. 

OKC
Betting Trends

  • The Thunder boast a 54–26–2 ATS record this season, covering 67.5% of their games, the best in the NBA.

MATCHUP TRENDS

  • The Thunder have covered the spread in all four meetings against the Grizzlies this season, winning each game by double digits.

MEM vs. OKC
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: J. Jackson over 18.5 PTS+AST.

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Memphis vs Oklahoma City Prediction & Odds:
Free NBA Betting Insights for 4/22/25

The Memphis Grizzlies and Oklahoma City Thunder square off in Game 2 of their Western Conference first-round playoff series on April 22, 2025, with the Thunder holding a 1–0 lead after a commanding 125–104 win in Game 1 at Paycom Center. The top-seeded Thunder looked every bit the part of a postseason powerhouse in the opener, combining elite offensive execution with stifling defense to take firm control of the series. Shai Gilgeous-Alexander was the centerpiece of their success, exploding for 37 points on efficient shooting while also dishing out 8 assists and grabbing 5 rebounds, continuing a season where he’s firmly established himself as one of the NBA’s elite two-way players. Oklahoma City’s supporting cast delivered as well, with Jalen Williams, Chet Holmgren, and Josh Giddey each contributing on both ends—Holmgren in particular provided a defensive anchor in the paint and a floor-spacing threat that pulled Memphis’s bigs away from the basket. The Thunder’s ability to move the ball, create clean looks from deep, and convert in transition gave them full control of Game 1 from the second quarter onward, and they showed no signs of the postseason jitters typically associated with young squads. For the Grizzlies, the loss served as a wake-up call—highlighting issues with defensive breakdowns, poor shot selection, and an inability to contain the Thunder’s speed and spacing. Memphis entered this series as clear underdogs, and their performance in Game 1 reinforced the gap they must bridge if they intend to make this competitive. Ja Morant, while a dynamic talent, struggled under the pressure of OKC’s defense and finished with more turnovers than assists, a trend that cannot continue if Memphis hopes to steal a game on the road. Jaren Jackson Jr. offered solid production in stretches, but he was plagued by foul trouble, a recurring issue that limits his availability and aggressiveness on both ends.

Desmond Bane and Marcus Smart attempted to provide backcourt stability and defensive resistance, but Oklahoma City’s ball movement and shooting quickly neutralized their efforts. The Grizzlies will need to make several tactical adjustments—improving defensive rotations, cutting down on live-ball turnovers, and generating higher-percentage looks through pick-and-roll sets or interior post-ups—to avoid falling into an 0–2 hole. They were thoroughly outmatched on the boards and struggled to defend in space, particularly when the Thunder spread the floor with Holmgren at center and surrounded him with shooters. Coach Taylor Jenkins will be tasked with refocusing his group and finding lineup combinations that can compete with OKC’s pace without sacrificing defensive integrity. As for the Thunder, Game 2 presents an opportunity to solidify their control of the series and continue building postseason confidence in front of one of the most energized home crowds in the league. Their 54–26–2 ATS record—the best in the NBA—reflects how consistently they’ve outperformed expectations all season, and their performance in Game 1 was a seamless continuation of their regular season dominance. Mark Daigneault’s squad plays with maturity beyond its years, executing clean sets, communicating defensively, and staying composed in crunch-time scenarios. If the Thunder replicate their Game 1 intensity, limit second-chance opportunities, and continue forcing the Grizzlies into contested jumpers, they will remain firmly in control. But playoff series can shift quickly, and Memphis—though outgunned in the opener—still possesses explosive firepower and postseason experience that can surface under the right conditions. Game 2 will test whether the Thunder can sustain their level or whether the Grizzlies have a counterpunch ready. With momentum on the line and both teams aware of the stakes, Tuesday night’s showdown could define the tone for the rest of the series.

Memphis Grizzlies NBA Preview

The Memphis Grizzlies enter Game 2 of their first-round playoff series against the Oklahoma City Thunder with their backs already against the wall after a deflating 125–104 loss in Game 1—a performance that exposed critical defensive gaps, turnovers under pressure, and a lack of cohesion on both ends of the floor. Ja Morant, the engine of Memphis’s offense, was held in check by the Thunder’s length and disciplined defensive scheme, finishing with a stat line that belied his usual explosiveness and featured more turnovers than assists. It was clear from the opening tip that the Grizzlies were on their heels, struggling to match Oklahoma City’s tempo, spacing, and ball movement. Jaren Jackson Jr., typically a two-way force for Memphis, was limited by early foul trouble and failed to make a consistent impact either as a rim protector or scorer, which further complicated Memphis’s ability to control the paint or generate any rhythm offensively. Desmond Bane and Marcus Smart offered effort and grit, but the team-wide shooting struggles and inability to contain Shai Gilgeous-Alexander’s drives left Memphis searching for answers and trailing by double digits for most of the second half. Taylor Jenkins’ group now faces the pressure of adapting quickly to a Thunder team that has beaten them four times this season—all by double digits—and has shown no signs of letting up. To have a fighting chance in Game 2, the Grizzlies must commit to a more physical and focused defensive approach, particularly on the perimeter where OKC’s spacing and off-ball movement shredded their rotations in Game 1. Memphis was consistently caught chasing, allowing open threes and failing to contain penetration at the point of attack, which led to breakdowns that bled into every layer of their defensive structure. Jenkins will need to explore more aggressive trapping or switching schemes to disrupt the Thunder’s timing and take some pressure off individual defenders, especially with OKC’s ability to attack mismatches.

Offensively, Memphis needs to establish a more deliberate pace and play through Morant in ways that don’t rely solely on isolation or transition. That starts with cleaner execution in half-court sets, better screening actions, and more active movement off the ball to free up their shooters and reduce defensive congestion. The Grizzlies also must close the rebounding gap—OKC dominated second-chance points, and without stronger effort on the glass from Jackson, Tillman, or Aldama, Memphis will continue to lose the possession battle. Game 2 is as close to a must-win as it gets for Memphis this early in the series. A 0–2 deficit heading back to FedExForum would put them in a nearly insurmountable position against a top-seeded Thunder squad that has confidence, youth, and momentum on its side. The Grizzlies must lean on their playoff experience, including their deeper runs in recent years, to ground themselves and bring a sharper, more physical brand of basketball on Tuesday night. If Morant can bounce back with a 30+ point performance, if Jackson can stay on the floor, and if the supporting cast hits timely threes while defending with urgency, Memphis can flip the script and reclaim belief that this series isn’t over. But if they come out with anything less than desperation and discipline, the Thunder’s speed, poise, and depth may once again overwhelm them and push them to the brink.

The Oklahoma City Thunder host the Memphis Grizzlies in Game 2 of their Western Conference first-round playoff series on April 22, 2025, at Paycom Center. The Thunder lead the series 1–0 after a commanding 125–104 victory in Game 1, showcasing their dominance as the top seed. Memphis vs Oklahoma City AI Prediction: Free NBA Betting Insights for Apr 22. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Oklahoma City Thunder NBA Preview

The Oklahoma City Thunder enter Game 2 of their first-round playoff series against the Memphis Grizzlies with supreme confidence and momentum after a dominant 125–104 victory in Game 1 that showcased why they earned the Western Conference’s top seed. Powered by a blistering performance from Shai Gilgeous-Alexander, who poured in 37 points with surgical efficiency, the Thunder executed a nearly flawless game plan on both ends of the court. They shot over 52% from the field, moved the ball with pace and precision, and completely outmaneuvered a Grizzlies defense that looked several steps behind for much of the night. Oklahoma City’s offense wasn’t just about individual brilliance—it was a masterclass in spacing, unselfishness, and off-ball movement, with Jalen Williams, Chet Holmgren, and Josh Giddey each stepping into their roles seamlessly. Holmgren, in particular, was pivotal defensively, altering shots at the rim and anchoring the paint while simultaneously stretching Memphis’s frontcourt with his perimeter shooting. The Thunder’s depth was another major asset, with bench players contributing in key stretches and maintaining the team’s rhythm even when the starters rested, further underscoring the team’s versatility and cohesion under head coach Mark Daigneault. Defensively, Oklahoma City showed maturity well beyond their years, using length, communication, and relentless energy to disrupt Memphis’s offensive sets and shut down secondary actions. The Thunder’s perimeter defenders consistently stayed attached to shooters, hedged effectively on screens, and collapsed quickly to protect the paint—limiting Memphis to just 104 points and forcing them into contested looks for most of the night. Shai and Giddey were particularly active defensively, combining for multiple deflections and helping generate 17 Memphis turnovers that led to transition opportunities and easy buckets.

The Thunder also dominated the rebounding battle, using Holmgren’s timing and the collective box-out efforts of their wings to limit second-chance points and keep the Grizzlies from gaining traction on the offensive glass. As a team that led the NBA in ATS percentage throughout the season (54–26–2), Oklahoma City not only played to their seed but exceeded expectations with a poise that echoed that of a battle-tested veteran group rather than a young squad in its playoff infancy. With Game 2 again on their home floor at Paycom Center, where they’ve thrived all year, the Thunder now have a chance to take a commanding 2–0 lead and put the Grizzlies on the brink before the series shifts to Memphis. The focus for OKC heading into Game 2 will be maintaining their defensive intensity while continuing to lean on the balanced, high-IQ offense that has made them one of the league’s most efficient teams. If Gilgeous-Alexander can continue setting the tone with early scoring and penetration, and if Holmgren and Williams maintain their two-way impact, the Thunder will once again be in position to control the game’s pace and dictate matchups. The home crowd energy will also play a role—feeding the Thunder’s fast breaks, igniting big runs, and helping keep the Grizzlies off balance. That said, Daigneault and the team will remain focused on not letting up, knowing that Memphis still possesses explosive scorers and postseason experience capable of flipping momentum quickly. But if Oklahoma City executes with the same clarity, cohesion, and confidence they displayed in Game 1, they won’t just be defending home court—they’ll be stamping their authority on the series and reinforcing their case as a legitimate title contender in the Western Conference.

Memphis vs. Oklahoma City Prop Picks (AI)

AI algorithm Remi is pouring through tons of stats on each team. In fact, anytime the Grizzlies and Thunder play there’s always several intriguing angles to key in on. Not to mention games played at Paycom Center in Apr almost always follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: J. Jackson over 18.5 PTS+AST.

Memphis vs. Oklahoma City Prediction (AI)

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Remi, our AI sports wizard, has been pouring over mountains of data from every past game between the Grizzlies and Thunder and using recursive machine learning and industry leading AI to examine the data to a single cover probability.

Interestingly enough, the data has been most watching on the linear correlation of weight knucklehead sportsbettors tend to put on Oklahoma City’s strength factors between a Grizzlies team going up against a possibly rested Thunder team. Trends look to say the true game analytics appear to reflect a strong lean against one Vegas line specifically.

Unlock this in-depth AI prediction and all of our NBA AI picks for FREE now.

Below is our current AI Memphis vs Oklahoma City picks, computer picks Grizzlies vs Thunder, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
NBA 11/8 POR@MIA UNLOCK THIS PICK 7 VAULT v3 Locked VAULT v3
NBA 11/8 LAL@ATL UNLOCK THIS PICK 6 VAULT v2 Locked VAULT v2
NBA 11/8 IND@DEN UNLOCK THIS PICK 0 INTEL Locked INTEL
NBA 11/8 CHI@CLE UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NBA schedule.

Grizzlies Betting Trends

The Grizzlies have a 41–40–1 record against the spread (ATS) this season, covering 50.6% of their games. 

Thunder Betting Trends

The Thunder boast a 54–26–2 ATS record this season, covering 67.5% of their games, the best in the NBA.

Grizzlies vs. Thunder Matchup Trends

The Thunder have covered the spread in all four meetings against the Grizzlies this season, winning each game by double digits.

Memphis vs. Oklahoma City Game Info

Memphis vs Oklahoma City starts on April 22, 2025 at 7:30 PM EST.

Spread: Oklahoma City -14.5
Moneyline: Memphis +721, Oklahoma City -1149
Over/Under: 229.5

Memphis: (48-34)  |  Oklahoma City: (68-14)

Remi's searched hard and found the best prop for this matchup: J. Jackson over 18.5 PTS+AST.. Prices move—always shop for the best number.

The Thunder have covered the spread in all four meetings against the Grizzlies this season, winning each game by double digits.

MEM trend: The Grizzlies have a 41–40–1 record against the spread (ATS) this season, covering 50.6% of their games. 

OKC trend: The Thunder boast a 54–26–2 ATS record this season, covering 67.5% of their games, the best in the NBA.

See our latest NBA picks and odds pages for 2025 to compare prices before you bet.

Memphis vs. Oklahoma City Odds

AI algorithm Remi is pouring through loads of data on each player. In fact, anytime the Memphis vs Oklahoma City trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme altitude can often follow normal, predictable betting trends.

Memphis vs Oklahoma City Opening Odds

MEM Moneyline: +721
OKC Moneyline: -1149
MEM Spread: +14.5
OKC Spread: -14.5
Over/Under: 229.5

Memphis vs Oklahoma City Live Odds

Games PTS ML SPR O/U
Nov 9, 2025 3:30PM EST
Houston Rockets
Milwaukee Bucks
11/9/25 3:30PM
Rockets
Bucks
-174
+146
-4 (-106)
+4 (-114)
O 232.5 (-108)
U 232.5 (-112)
Nov 9, 2025 6:00PM EST
Brooklyn Nets
New York Knicks
11/9/25 6PM
Nets
Knicks
+730
-1150
+15.5 (-108)
-15.5 (-112)
O 228.5 (-108)
U 228.5 (-112)
Nov 9, 2025 6:10PM EST
Oklahoma City Thunder
Memphis Grizzlies
11/9/25 6:10PM
Thunder
Grizzlies
-600
+450
-10.5 (-118)
+10.5 (-104)
O 233.5 (-110)
U 233.5 (-110)
Nov 9, 2025 6:10PM EST
Boston Celtics
Orlando Magic
11/9/25 6:10PM
Celtics
Magic
+126
-148
+3.5 (-114)
-3.5 (-106)
O 227.5 (-110)
U 227.5 (-110)
Nov 9, 2025 7:30PM EST
Detroit Pistons
Philadelphia 76ers
11/9/25 7:30PM
Pistons
76ers
-174
+144
-4.5 (-108)
+4.5 (-112)
O 232.5 (-110)
U 232.5 (-110)
Nov 9, 2025 8:40PM EST
Indiana Pacers
Golden State Warriors
11/9/25 8:40PM
Pacers
Warriors
+460
-620
+12.5 (-110)
-12.5 (-110)
O 228.5 (-112)
U 228.5 (-108)
Nov 9, 2025 9:10PM EST
Minnesota Timberwolves
Sacramento Kings
11/9/25 9:10PM
Timberwolves
Kings
-230
+190
-5.5 (-110)
+5.5 (-110)
O 235.5 (-110)
U 235.5 (-110)
Dec 25, 2025 12:00PM EST
Cleveland Cavaliers
New York Knicks
12/25/25 12PM
Cavaliers
Knicks
+117
-143
+2.5 (-113)
-2.5 (-113)
O 229.5 (-113)
U 229.5 (-113)
Dec 25, 2025 5:00PM EST
Dallas Mavericks
Golden State Warriors
12/25/25 5PM
Mavericks
Warriors
+150
-195
+4.5 (-112)
-4.5 (-114)
O 227 (-115)
U 227 (-110)
Dec 25, 2025 10:30PM EST
Minnesota Timberwolves
Denver Nuggets
12/25/25 10:30PM
Timberwolves
Nuggets
+175
-220
+5 (-109)
-5 (-117)
O 229.5 (-112)
U 229.5 (-114)

NBA Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Memphis Grizzlies vs. Oklahoma City Thunder on April 22, 2025 at Paycom Center.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our NBA odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
DAL@MEM MEM -4 56.3% 6 WIN
TOR@ATL TOR +118 48.0% 3 WIN
CHA@MIA OVER 235.5 54.3% 3 LOSS
LAC@PHX PHX -135 58.9% 7 WIN
PHI@CLE PHI +10.5 53.3% 3 LOSS
MIA@DEN MIA +9.5 53.7% 3 LOSS
OKC@POR POR +4.5 52.9% 3 WIN
HOU@MEM MEM +8.5 54.7% 4 LOSS
UTA@DET UTA +10 56.8% 6 LOSS
NO@DAL TREY MURPHY III OVER 25.5 PTS & REB 55.5% 5 LOSS
ORL@ATL ORL -3.5 56.5% 6 LOSS
MIL@TOR MIL +3.5 56.5% 4 LOSS
PHX@GS STEPH CURRY UNDER 4.5 THREE PTRS MADE 53.3% 3 LOSS
OKC@LAC JAMES HARDEN OVER 12.5 REBOUNDS + ASSTS 56.1% 6 LOSS
LAL@POR POR -2.5 54.7% 4 LOSS
SA@PHX SA -5.5 56.6% 6 LOSS
ORL@WAS WAS +9 54.2% 4 LOSS
DAL@DET DAL +8 58.7% 8 LOSS
NY@CHI NY -4.5 54.7% 4 LOSS
BOS@PHI BOS +1.5 54.6% 4 WIN
TOR@CLE TOR +6 56.2% 6 WIN
DEN@POR JERAMI GRANT OVER 1.5 TURNOVERS 56.6% 6 WIN
WAS@OKC WAS +15.5 54.9% 4 LOSS
NO@DEN DEN -12.5 53.6% 3 WIN
NO@DEN NIKOLA JOKIC OVER 26.5 POINTS 56.6% 6 LOSS
SAC@OKC SAC +10 54.7% 4 WIN
NY@MIL MIL +3 56.6% 6 WIN
LAC@GS GS +2.5 56.8% 6 WIN
LAC@GS BRANDIN PODZIEMSKI UNDER 1.5 THREE POINTERS MADE 55.5% 5 LOSS
CLE@DET DET +2.5 53.5% 3 LOSS
ORL@PHI ORL -5 54.7% 4 LOSS
OKC@DAL DAL +9 66.4% 6 WIN
BOS@NO NO +2 55.6% 5 LOSS
BKN@HOU BKN +16.5 57.0% 7 LOSS
BOS@NO TREY MURPHY III UNDER 25.5 PTS + REB 54.4% 4 WIN
MIL@CLE MIL +6.5 56.1% 6 WIN
POR@LAC POR +8.5 56.5% 6 WIN
ATL@ORL ATL +5 54.6% 4 WIN
WAS@DAL WAS +10 55.3% 5 WIN
PHX@LAC IVICA ZUBAC OVER 6.5 MADE FIELD GOALS 55.5% 5 LOSS
OKC@IND IND +8 56.5% 6 WIN
CLE@NY CLE -116 55.0% 4 LOSS
LAC@UTA UTA +9.5 54.1% 4 WIN
WAS@MIL KYLE KUZMA OVER 1.5 ASSTS 55.5% 5 WIN
HOU@OKC HOU +6.5 54.8% 4 WIN
GS@LAL STEPHEN CURRY UNDER 2.5 TURNOVERS 54.4 4 WIN
IND@OKC SHAI GILGEOUS-ALEXANDER OVER 1.5 STEALS 54.90% 4 LOSS
IND@OKC JALEN WILLIAMS OVER 0.5 1Q REBOUNDS 55.70% 5 WIN
OKC@IND TJ MCCONNELL UNDER 7.5 TWO POINT ATT 55.70% 5 LOSS
IND@OKC CHET HOLMGREN OVER 1.5 SHOTS BLOCKED 53.40% 3 WIN
OKC@IND TJ MCCONNELL OVER 1.5 TURNOVERS 53.00% 3 LOSS