Grizzlies vs. Thunder
Prediction, Odds & Props
Apr 22 | NBA AI Picks

Updated: 2025-04-20T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Oklahoma City Thunder host the Memphis Grizzlies in Game 2 of their Western Conference first-round playoff series on April 22, 2025, at Paycom Center. The Thunder lead the series 1–0 after a commanding 125–104 victory in Game 1, showcasing their dominance as the top seed.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Apr 22, 2025

Start Time: 7:30 PM EST​

Venue: Paycom Center​

Thunder Record: (68-14)

Grizzlies Record: (48-34)

OPENING ODDS

MEM Moneyline: +721

OKC Moneyline: -1149

MEM Spread: +14.5

OKC Spread: -14.5

Over/Under: 229.5

MEM
Betting Trends

  • The Grizzlies have a 41–40–1 record against the spread (ATS) this season, covering 50.6% of their games. 

OKC
Betting Trends

  • The Thunder boast a 54–26–2 ATS record this season, covering 67.5% of their games, the best in the NBA.

MATCHUP TRENDS

  • The Thunder have covered the spread in all four meetings against the Grizzlies this season, winning each game by double digits.

MEM vs. OKC
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: J. Jackson over 18.5 PTS+AST.

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Memphis vs Oklahoma City Prediction & Odds:
Free NBA Betting Insights for 4/22/25

The Memphis Grizzlies and Oklahoma City Thunder square off in Game 2 of their Western Conference first-round playoff series on April 22, 2025, with the Thunder holding a 1–0 lead after a commanding 125–104 win in Game 1 at Paycom Center. The top-seeded Thunder looked every bit the part of a postseason powerhouse in the opener, combining elite offensive execution with stifling defense to take firm control of the series. Shai Gilgeous-Alexander was the centerpiece of their success, exploding for 37 points on efficient shooting while also dishing out 8 assists and grabbing 5 rebounds, continuing a season where he’s firmly established himself as one of the NBA’s elite two-way players. Oklahoma City’s supporting cast delivered as well, with Jalen Williams, Chet Holmgren, and Josh Giddey each contributing on both ends—Holmgren in particular provided a defensive anchor in the paint and a floor-spacing threat that pulled Memphis’s bigs away from the basket. The Thunder’s ability to move the ball, create clean looks from deep, and convert in transition gave them full control of Game 1 from the second quarter onward, and they showed no signs of the postseason jitters typically associated with young squads. For the Grizzlies, the loss served as a wake-up call—highlighting issues with defensive breakdowns, poor shot selection, and an inability to contain the Thunder’s speed and spacing. Memphis entered this series as clear underdogs, and their performance in Game 1 reinforced the gap they must bridge if they intend to make this competitive. Ja Morant, while a dynamic talent, struggled under the pressure of OKC’s defense and finished with more turnovers than assists, a trend that cannot continue if Memphis hopes to steal a game on the road. Jaren Jackson Jr. offered solid production in stretches, but he was plagued by foul trouble, a recurring issue that limits his availability and aggressiveness on both ends.

Desmond Bane and Marcus Smart attempted to provide backcourt stability and defensive resistance, but Oklahoma City’s ball movement and shooting quickly neutralized their efforts. The Grizzlies will need to make several tactical adjustments—improving defensive rotations, cutting down on live-ball turnovers, and generating higher-percentage looks through pick-and-roll sets or interior post-ups—to avoid falling into an 0–2 hole. They were thoroughly outmatched on the boards and struggled to defend in space, particularly when the Thunder spread the floor with Holmgren at center and surrounded him with shooters. Coach Taylor Jenkins will be tasked with refocusing his group and finding lineup combinations that can compete with OKC’s pace without sacrificing defensive integrity. As for the Thunder, Game 2 presents an opportunity to solidify their control of the series and continue building postseason confidence in front of one of the most energized home crowds in the league. Their 54–26–2 ATS record—the best in the NBA—reflects how consistently they’ve outperformed expectations all season, and their performance in Game 1 was a seamless continuation of their regular season dominance. Mark Daigneault’s squad plays with maturity beyond its years, executing clean sets, communicating defensively, and staying composed in crunch-time scenarios. If the Thunder replicate their Game 1 intensity, limit second-chance opportunities, and continue forcing the Grizzlies into contested jumpers, they will remain firmly in control. But playoff series can shift quickly, and Memphis—though outgunned in the opener—still possesses explosive firepower and postseason experience that can surface under the right conditions. Game 2 will test whether the Thunder can sustain their level or whether the Grizzlies have a counterpunch ready. With momentum on the line and both teams aware of the stakes, Tuesday night’s showdown could define the tone for the rest of the series.

Memphis Grizzlies NBA Preview

The Memphis Grizzlies enter Game 2 of their first-round playoff series against the Oklahoma City Thunder with their backs already against the wall after a deflating 125–104 loss in Game 1—a performance that exposed critical defensive gaps, turnovers under pressure, and a lack of cohesion on both ends of the floor. Ja Morant, the engine of Memphis’s offense, was held in check by the Thunder’s length and disciplined defensive scheme, finishing with a stat line that belied his usual explosiveness and featured more turnovers than assists. It was clear from the opening tip that the Grizzlies were on their heels, struggling to match Oklahoma City’s tempo, spacing, and ball movement. Jaren Jackson Jr., typically a two-way force for Memphis, was limited by early foul trouble and failed to make a consistent impact either as a rim protector or scorer, which further complicated Memphis’s ability to control the paint or generate any rhythm offensively. Desmond Bane and Marcus Smart offered effort and grit, but the team-wide shooting struggles and inability to contain Shai Gilgeous-Alexander’s drives left Memphis searching for answers and trailing by double digits for most of the second half. Taylor Jenkins’ group now faces the pressure of adapting quickly to a Thunder team that has beaten them four times this season—all by double digits—and has shown no signs of letting up. To have a fighting chance in Game 2, the Grizzlies must commit to a more physical and focused defensive approach, particularly on the perimeter where OKC’s spacing and off-ball movement shredded their rotations in Game 1. Memphis was consistently caught chasing, allowing open threes and failing to contain penetration at the point of attack, which led to breakdowns that bled into every layer of their defensive structure. Jenkins will need to explore more aggressive trapping or switching schemes to disrupt the Thunder’s timing and take some pressure off individual defenders, especially with OKC’s ability to attack mismatches.

Offensively, Memphis needs to establish a more deliberate pace and play through Morant in ways that don’t rely solely on isolation or transition. That starts with cleaner execution in half-court sets, better screening actions, and more active movement off the ball to free up their shooters and reduce defensive congestion. The Grizzlies also must close the rebounding gap—OKC dominated second-chance points, and without stronger effort on the glass from Jackson, Tillman, or Aldama, Memphis will continue to lose the possession battle. Game 2 is as close to a must-win as it gets for Memphis this early in the series. A 0–2 deficit heading back to FedExForum would put them in a nearly insurmountable position against a top-seeded Thunder squad that has confidence, youth, and momentum on its side. The Grizzlies must lean on their playoff experience, including their deeper runs in recent years, to ground themselves and bring a sharper, more physical brand of basketball on Tuesday night. If Morant can bounce back with a 30+ point performance, if Jackson can stay on the floor, and if the supporting cast hits timely threes while defending with urgency, Memphis can flip the script and reclaim belief that this series isn’t over. But if they come out with anything less than desperation and discipline, the Thunder’s speed, poise, and depth may once again overwhelm them and push them to the brink.

The Oklahoma City Thunder host the Memphis Grizzlies in Game 2 of their Western Conference first-round playoff series on April 22, 2025, at Paycom Center. The Thunder lead the series 1–0 after a commanding 125–104 victory in Game 1, showcasing their dominance as the top seed. Memphis vs Oklahoma City AI Prediction: Free NBA Betting Insights for Apr 22. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Oklahoma City Thunder NBA Preview

The Oklahoma City Thunder enter Game 2 of their first-round playoff series against the Memphis Grizzlies with supreme confidence and momentum after a dominant 125–104 victory in Game 1 that showcased why they earned the Western Conference’s top seed. Powered by a blistering performance from Shai Gilgeous-Alexander, who poured in 37 points with surgical efficiency, the Thunder executed a nearly flawless game plan on both ends of the court. They shot over 52% from the field, moved the ball with pace and precision, and completely outmaneuvered a Grizzlies defense that looked several steps behind for much of the night. Oklahoma City’s offense wasn’t just about individual brilliance—it was a masterclass in spacing, unselfishness, and off-ball movement, with Jalen Williams, Chet Holmgren, and Josh Giddey each stepping into their roles seamlessly. Holmgren, in particular, was pivotal defensively, altering shots at the rim and anchoring the paint while simultaneously stretching Memphis’s frontcourt with his perimeter shooting. The Thunder’s depth was another major asset, with bench players contributing in key stretches and maintaining the team’s rhythm even when the starters rested, further underscoring the team’s versatility and cohesion under head coach Mark Daigneault. Defensively, Oklahoma City showed maturity well beyond their years, using length, communication, and relentless energy to disrupt Memphis’s offensive sets and shut down secondary actions. The Thunder’s perimeter defenders consistently stayed attached to shooters, hedged effectively on screens, and collapsed quickly to protect the paint—limiting Memphis to just 104 points and forcing them into contested looks for most of the night. Shai and Giddey were particularly active defensively, combining for multiple deflections and helping generate 17 Memphis turnovers that led to transition opportunities and easy buckets.

The Thunder also dominated the rebounding battle, using Holmgren’s timing and the collective box-out efforts of their wings to limit second-chance points and keep the Grizzlies from gaining traction on the offensive glass. As a team that led the NBA in ATS percentage throughout the season (54–26–2), Oklahoma City not only played to their seed but exceeded expectations with a poise that echoed that of a battle-tested veteran group rather than a young squad in its playoff infancy. With Game 2 again on their home floor at Paycom Center, where they’ve thrived all year, the Thunder now have a chance to take a commanding 2–0 lead and put the Grizzlies on the brink before the series shifts to Memphis. The focus for OKC heading into Game 2 will be maintaining their defensive intensity while continuing to lean on the balanced, high-IQ offense that has made them one of the league’s most efficient teams. If Gilgeous-Alexander can continue setting the tone with early scoring and penetration, and if Holmgren and Williams maintain their two-way impact, the Thunder will once again be in position to control the game’s pace and dictate matchups. The home crowd energy will also play a role—feeding the Thunder’s fast breaks, igniting big runs, and helping keep the Grizzlies off balance. That said, Daigneault and the team will remain focused on not letting up, knowing that Memphis still possesses explosive scorers and postseason experience capable of flipping momentum quickly. But if Oklahoma City executes with the same clarity, cohesion, and confidence they displayed in Game 1, they won’t just be defending home court—they’ll be stamping their authority on the series and reinforcing their case as a legitimate title contender in the Western Conference.

Memphis vs. Oklahoma City Prop Picks (AI)

AI algorithm Remi is pouring through loads of stats on each line. In fact, anytime the Grizzlies and Thunder play there’s always several intriguing observations to key in on. Not to mention games played at Paycom Center in Apr seemingly never follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: J. Jackson over 18.5 PTS+AST.

Memphis vs. Oklahoma City Prediction (AI)

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Remi, our AI sports algorithm, has been pouring over tons of data from every past game between the Grizzlies and Thunder and using recursive machine learning and impressive AI to boil down the data to a single cover probability.

Interestingly enough, the data has been most focused on the trending weight knucklehead sportsbettors often put on Memphis’s strength factors between a Grizzlies team going up against a possibly tired Thunder team. It appears the true game analytics appear to reflect a slight lean against one Vegas line specifically.

Unlock this in-depth AI prediction and all of our NBA AI picks for FREE now.

Below is our current AI Memphis vs Oklahoma City picks, computer picks Grizzlies vs Thunder, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NBA schedule.

Grizzlies Betting Trends

The Grizzlies have a 41–40–1 record against the spread (ATS) this season, covering 50.6% of their games. 

Thunder Betting Trends

The Thunder boast a 54–26–2 ATS record this season, covering 67.5% of their games, the best in the NBA.

Grizzlies vs. Thunder Matchup Trends

The Thunder have covered the spread in all four meetings against the Grizzlies this season, winning each game by double digits.

Memphis vs. Oklahoma City Game Info

Memphis vs Oklahoma City starts on April 22, 2025 at 7:30 PM EST.

Spread: Oklahoma City -14.5
Moneyline: Memphis +721, Oklahoma City -1149
Over/Under: 229.5

Memphis: (48-34)  |  Oklahoma City: (68-14)

Remi's searched hard and found the best prop for this matchup: J. Jackson over 18.5 PTS+AST.. Prices move—always shop for the best number.

The Thunder have covered the spread in all four meetings against the Grizzlies this season, winning each game by double digits.

MEM trend: The Grizzlies have a 41–40–1 record against the spread (ATS) this season, covering 50.6% of their games. 

OKC trend: The Thunder boast a 54–26–2 ATS record this season, covering 67.5% of their games, the best in the NBA.

See our latest NBA picks and odds pages for 2025 to compare prices before you bet.

Memphis vs. Oklahoma City Odds

AI algorithm Remi is pouring through tons of stats on each player. In fact, anytime the Memphis vs Oklahoma City trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme temps can often follow normal, predictable patterns.

Memphis vs Oklahoma City Opening Odds

MEM Moneyline: +721
OKC Moneyline: -1149
MEM Spread: +14.5
OKC Spread: -14.5
Over/Under: 229.5

Memphis vs Oklahoma City Live Odds

Games PTS ML SPR O/U
Oct 21, 2025 7:30PM EDT
Houston Rockets
Oklahoma City Thunder
10/21/25 7:30PM
Rockets
Thunder
+260
-320
+8 (-115)
-8 (-105)
O 225.5 (-110)
U 225.5 (-110)
Oct 21, 2025 10:00PM EDT
Golden State Warriors
Los Angeles Lakers
10/21/25 10PM
Warriors
Lakers
+150
-175
+4 (-110)
-4 (-110)
O 225.5 (-110)
U 225.5 (-110)
Oct 22, 2025 7:10PM EDT
Brooklyn Nets
Charlotte Hornets
10/22/25 7:10PM
Nets
Hornets
+136
-162
+3.5 (-110)
-3.5 (-110)
O 221 (-110)
U 221 (-110)
Oct 22, 2025 7:10PM EDT
Cleveland Cavaliers
New York Knicks
10/22/25 7:10PM
Cavaliers
Knicks
+145
-175
+3.5 (+100)
-3.5 (-120)
O 229.5 (+105)
U 229.5 (-125)
Oct 22, 2025 7:10PM EDT
Miami Heat
Orlando Magic
10/22/25 7:10PM
Heat
Magic
+280
-355
+8.5 (-110)
-8.5 (-110)
O 210.5 (-110)
U 210.5 (-110)
Oct 22, 2025 7:40PM EDT
Philadelphia 76ers
Boston Celtics
10/22/25 7:40PM
76ers
Celtics
+105
-125
+2 (-110)
-2 (-110)
O 224 (-110)
U 224 (-110)
Oct 22, 2025 7:40PM EDT
Toronto Raptors
Atlanta Hawks
10/22/25 7:40PM
Raptors
Hawks
+195
-238
+6 (-110)
-6 (-110)
O 233.5 (-110)
U 233.5 (-110)
Oct 22, 2025 8:10PM EDT
Washington Wizards
Milwaukee Bucks
10/22/25 8:10PM
Wizards
Bucks
+285
-360
+8.5 (-110)
-8.5 (-110)
O 226 (-110)
U 226 (-110)
Oct 22, 2025 8:10PM EDT
Detroit Pistons
Chicago Bulls
10/22/25 8:10PM
Pistons
Bulls
-130
+110
-2 (-110)
+2 (-110)
O 233.5 (-110)
U 233.5 (-110)
Oct 22, 2025 8:10PM EDT
New Orleans Pelicans
Memphis Grizzlies
10/22/25 8:10PM
Pelicans
Grizzlies
+150
-180
+4.5 (-110)
-4.5 (-110)
O 234 (-110)
U 234 (-110)
Oct 22, 2025 9:10PM EDT
Los Angeles Clippers
Utah Jazz
10/22/25 9:10PM
Clippers
Jazz
-325
+260
-8 (-110)
+8 (-110)
O 227.5 (-110)
U 227.5 (-110)
Oct 22, 2025 9:40PM EDT
San Antonio Spurs
Dallas Mavericks
10/22/25 9:40PM
Spurs
Mavericks
-110
-110
-1 (-105)
+1 (-115)
O 226.5 (-130)
U 226.5 (+105)
Oct 22, 2025 10:10PM EDT
Sacramento Kings
Phoenix Suns
10/22/25 10:10PM
Kings
Suns
-105
-115
+1 (-110)
-1 (-110)
O 229 (-110)
U 229 (-110)
Oct 22, 2025 10:10PM EDT
Minnesota Timberwolves
Portland Trail Blazers
10/22/25 10:10PM
Timberwolves
Trail Blazers
-142
+120
-2.5 (-110)
+2.5 (-110)
O 221 (-110)
U 221 (-110)
Oct 23, 2025 7:40PM EDT
Oklahoma City Thunder
Indiana Pacers
10/23/25 7:40PM
Thunder
Pacers
-325
+250
-7.5 (-110)
+7.5 (-110)
O 226.5 (-110)
U 226.5 (-110)
Oct 23, 2025 10:10PM EDT
Denver Nuggets
Golden State Warriors
10/23/25 10:10PM
Nuggets
Warriors
-110
-110
+1 (-110)
-1 (-110)
O 232.5 (-110)
U 232.5 (-110)

NBA Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Memphis Grizzlies vs. Oklahoma City Thunder on April 22, 2025 at Paycom Center.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our NBA odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
IND@OKC PASCAL SIAKAM OVER 2.5 PERSONAL FOULS 54.20% 4 WIN
IND@OKC IND +10 54.00% 3 WIN
IND@OKC BENNEDICT MATHURIN OVER 2.5 FREE THROW ATT 54.90% 4 WIN
NY@IND MYLES TURNER OVER 6 REBOUNDS + ASSTS 54.40% 4 LOSS
IND@NY IND +5 55.60% 5 LOSS
NY@IND JALEN BRUNSON UNDER 22 FIELD GOAL ATT 54.70% 4 WIN
OKC@MIN RUDY GOBERT OVER 1.5 FREE THROWS MADE 54.00% 4 WIN
OKC@MIN OKC -2.5 56.70% 6 LOSS
NY@IND KARL ANTHONY TOWNS OVER 32.5 POINTS + REBOUNDS 54.00% 4 WIN
OKC@MIN NAZ REID OVER 9.0 FIELD GOAL ATT 54.60% 4 LOSS
IND@NY MYLES TURNER OVER 5 MADE FIELD GOALS 53.60% 3 WIN
IND@NY NY -5.5 55.00% 4 LOSS
MIN@OKC ISAIAH HARTENSTEIN UNDER 7.5 REBOUNDS 53.00% 3 LOSS
MIN@OKC MIN +7.5 54.70% 4 LOSS
IND@NY TYRESE HALIBURTON ASSTS - UNDER 8.5 54.10% 4 LOSS
IND@NY IND +4.5 54.80% 4 WIN
MIN@OKC ALEX CARUSO UNDER 2.5 ASSTS 54.10% 4 WIN
DEN@OKC MICHAEL PORTER UNDER 7.5 REBS + AST 54.80% 4 WIN
BOS@NY NY -2.5 55.60% 5 WIN
GS@MIN DONTE DIVINCENZO OVER 1.5 TURNOVERS 54.80% 4 LOSS
GS@MIN GS +10.5 54.70% 4 LOSS
DEN@OKC NIKOLA JOKIC UNDER 22.5 REBOUNDS + ASSTS 54.00% 4 WIN
MIN@GS JIMMY BUTLER UNDER 33.5 POINTS + REBOUNDS 54.50% 4 WIN
BOS@NY BOS -5.5 54.70% 4 WIN
OKC@DEN OKC -5 55.70% 5 LOSS
DEN@OKC SHAI GILGEOUS-ALEXANDER UNDER 12.5 REBOUNDS + ASSTS 54.20% 4 WIN
IND@CLE IND +8 54.00% 3 WIN
GS@MIN ANTHONY EDWARDS UNDER 40.5 PTS+REB+AST 54.00% 4 WIN
GS@MIN MIN -6.5 54.40% 4 LOSS
DEN@OKC NIKOLA JOKIC UNDER 36.5 POINTS + ASSTS 53.20% 3 LOSS
IND@CLE IND +8.5 55.70% 5 WIN
HOU@GS GS -5 53.70% 3 LOSS
HOU@GS BRANDIN PODZIEMSKI UNDER 5.5 REBOUNDS 54.10% 4 LOSS
DEN@LAC MICHAEL PORTER UNDER 7.5 REBS + AST 53.20% 3 WIN
DEN@LAC UNDER 212.5 54.00% 3 LOSS
MIN@LAL MIN +6 53.80% 3 WIN
MIN@LAL NAZ REID OVER 1.5 ASSTS 54.80% 4 WIN
LAC@DEN IVICA ZUBAC OVER 1.5 TURNOVERS 53.50% 3 LOSS
DET@NY DET +5.5 53.90% 3 WIN
CLE@MIA EVAN MOBLEY UNDER 29.5 PTS+REB+AST 53.90% 3 WIN
BOS@ORL KRISTAPS PORZINGIS UNDER 8.5 REBOUNDS + ASSTS 53.10% 3 WIN
HOU@GS GS -3 53.70% 3 WIN
HOU@GS JALEN GREEN OVER 2.5 TURNOVERS 54.40% 4 LOSS
LAL@MIN LEBRON JAMES UNDER 31.5 POINTS + REBOUNDS 54.50% 4 LOSS
BOS@ORL BOS -3.5 54.70% 4 LOSS
DEN@LAC BOGDAN BOGDANOVIC OVER 2.5 THREE POINTERS ATTEMPTED 53.60% 3 LOSS
GS@HOU JALEN GREEN UNDER 3.5 FREE THROWS MADE 54.40% 4 LOSS
ORL@BOS ORL +10.5 54.70% 4 WIN
MEM@OKC ISAIAH HARTENSTEIN OVER 19.5 PTS + REB 53.80% 3 LOSS
MEM@OKC OKC -14.5 54.80% 4 WIN
LAC@DEN IVICA ZUBAC OVER 3.5 OFFENSIVE REBOUNDS 53.30% 3 LOSS