Clippers vs Nuggets Prediction — AI Finds CAN'T MISS NBA Lines & Props (Apr 21)

Updated: 2025-04-19T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Denver Nuggets and Los Angeles Clippers clash in Game 2 of their Western Conference first-round playoff series on April 21, 2025, at Ball Arena in Denver. The Nuggets lead the series 1–0 after a thrilling 112–110 overtime victory in Game 1.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Apr 21, 2025

Start Time: 10:00 PM EST​

Venue: Ball Arena​

Nuggets Record: (50-32)

Clippers Record: (50-32)

OPENING ODDS

LAC Moneyline: -119

DEN Moneyline: -100

LAC Spread: -1.5

DEN Spread: +1.5

Over/Under: 218

LAC
Betting Trends

  • The Clippers have struggled against the spread (ATS) on the road, with a 19–22 ATS record during the regular season.

DEN
Betting Trends

  • The Nuggets have been inconsistent at home, posting a 26–15 ATS record during the regular season.

MATCHUP TRENDS

  • The Nuggets have gone 7–16 ATS since March 1, including their Game 1 performance, indicating a recent trend of underperforming against the spread. 

LAC vs. DEN
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: C. Braun over 14.5 PTS+AST.

LIVE NBA ODDS

NBA ODDS COMPARISON

WANT MORE AI PICKS?

VAULT
VS. SPREAD
341-258
VAULT
NET UNITS
(INCL VIG)
+373.5
VAULT
NET PROFIT
(INCL VIG)
$100/UNIT
$37,349
EXECUTIVE
VS. SPREAD
1598-1366
EXECUTIVE
NET UNITS
(INCL VIG)
+376.6
EXECUTIVE
NET PROFIT
(INCL VIG)
$100/UNIT
$37,657

AI SPORTS PICK PRODUCTS

Create a Free Account

‘Create an Account’ to Get Remi’s Picks Today.

Remi Finds New Picks

Remi calculates the probability a team will cover the line.

Remi Works 24/7

Remi uses this probability to assign units to each pick.

Get Remi's AI Picks

Get Remi’s Top AI Sports Picks sent direct to your inbox.

Los Angeles Clippers vs Denver Prediction & Odds:
Free NBA Betting Insights for 4/21/25

The Denver Nuggets and Los Angeles Clippers prepare to face off in Game 2 of their Western Conference first-round playoff series on April 21, 2025, at Ball Arena, with the Nuggets holding a narrow 1–0 lead following a thrilling 112–110 overtime win in Game 1. The opening game was an instant classic, featuring elite shot-making, high-stakes defense, and a late-game chess match between two veteran-heavy lineups with championship ambitions. Nikola Jokić led the way for Denver with a near triple-double—29 points, 12 assists, and 9 rebounds—once again proving his ability to control the game’s tempo, while Jamal Murray added a clutch 24 points, including critical baskets down the stretch in overtime. Despite Denver’s offensive firepower, the Clippers were very much in control for large stretches of the game and likely walked away frustrated after giving up a late lead due to turnovers, including seven from Kawhi Leonard, whose 28-point, 9-rebound effort was otherwise dominant. Los Angeles played a physical brand of defense that disrupted the Nuggets’ half-court rhythm and saw excellent minutes from Ivica Zubac, who held his own against Jokić in the paint. However, Denver’s ability to generate quality looks through ball movement and secondary actions ultimately made the difference late in the contest. Heading into Game 2, both teams will look to fine-tune their late-game execution. The Clippers will be particularly focused on taking care of the basketball, as their 20 total turnovers in Game 1 significantly diminished their chances of stealing a game on the road. Paul George had a relatively quiet scoring night, and for Los Angeles to steal a game in Denver, he’ll need to play a more assertive offensive role alongside Leonard. On the defensive end, the Clippers largely succeeded in slowing down Denver’s perimeter attack, holding the Nuggets to modest three-point efficiency and forcing tough looks for everyone not named Jokić.

Where the Clippers will need to adjust is on the glass and in transition defense—two areas where Denver repeatedly found extra opportunities. Meanwhile, Denver knows that despite winning Game 1, they cannot afford complacency. Their 7–16 ATS record since March 1 suggests some struggles in meeting expectations, and with the Clippers hungry to even the series, head coach Michael Malone will need to reinforce focus on limiting second-chance points and reducing defensive lapses on high pick-and-rolls involving Leonard and George. Game 2 promises to be another tightly contested affair with high-intensity possessions, strategic adjustments, and pressure mounting on both sides. If Denver can continue to capitalize on their home-court advantage—where they’ve gone 26–15 ATS this season—and execute their offense with the fluidity they displayed in overtime, they’ll be well-positioned to take a 2–0 lead. On the other hand, if the Clippers cut down their turnovers, get more consistent scoring from their bench, and receive a bounce-back performance from George, they have more than enough firepower and playoff experience to even the series before heading back to Los Angeles. With both teams showing flashes of brilliance and areas for growth, Game 2 could set the tone for what’s shaping up to be one of the most competitive first-round series in the Western Conference. Expect physical play, deliberate pacing, and an atmosphere charged with playoff intensity as the Nuggets look to hold serve at home and the Clippers aim to punch back.

Los Angeles Clippers Clippers NBA Preview

The Los Angeles Clippers enter Game 2 of their Western Conference first-round playoff series against the Denver Nuggets looking to bounce back from a narrow 112–110 overtime loss in Game 1—a contest that showcased their defensive intensity, physicality, and playoff-tested poise but ultimately exposed critical late-game execution flaws. Kawhi Leonard led the way with 28 points and 9 rebounds, but his uncharacteristic 7 turnovers loomed large, particularly in crunch time where decision-making and ball security are non-negotiable. Despite the result, the Clippers’ performance gave them reasons for optimism, as they held the lead late in regulation, executed a defensive game plan that largely kept Denver’s shooters in check, and saw Ivica Zubac battle Nikola Jokić effectively in the paint. Zubac’s ability to stay vertical, protect the rim, and rebound through contact allowed L.A. to keep the rebounding battle close, while Terance Mann, James Harden, and Russell Westbrook each had moments of impact on both ends. However, 20 team turnovers and some stagnant offensive possessions down the stretch prevented them from closing the door on a potential road upset. Head coach Tyronn Lue will now challenge his team to stay sharp, clean up careless mistakes, and bring the same physical edge into Game 2—but with better control and execution under pressure. Offensively, the Clippers will need more from Paul George, who was unusually quiet in Game 1, particularly late in the fourth quarter and into overtime when his scoring and perimeter shot-making were needed most. George’s ability to create off the dribble and knock down contested jumpers can alleviate some of the pressure on Leonard, who faced double-teams and constant hedging from Denver’s defense. Expect Lue to design early sets to get George going, whether through pin-down actions, pick-and-roll mismatches, or spot-up opportunities in the corner.

Meanwhile, Harden and Westbrook will need to manage the game with composure, balancing their roles as secondary scorers with the need to facilitate ball movement and keep the offense from stagnating. The Clippers’ bench remains one of the deeper units in the playoffs, and continued contributions from Norman Powell and Mason Plumlee could be critical, especially if they can outplay Denver’s second unit and win those middle-of-the-quarter stretches when the starters rest. Defensively, the Clippers were effective in forcing Denver into tough looks and limiting second-chance points, but they’ll need to stay out of foul trouble and sharpen their closeouts to keep the Nuggets’ rhythm disrupted. The mission for Los Angeles in Game 2 is simple: maintain the defensive intensity that gave them control for much of Game 1, but eliminate the self-inflicted wounds that cost them the game. With a 19–22 ATS record on the road this season, the Clippers know they must play nearly flawless basketball to pull off a win in the altitude of Ball Arena. But with playoff-tested stars, a versatile and experienced supporting cast, and the tactical acumen of Ty Lue, this team is built for adjustments and responses. Game 2 is as much about mental resilience as it is tactical execution; a win sends the series back to Los Angeles tied and full of momentum, while a loss would mean falling into a dangerous 0–2 hole against the reigning champions. Expect the Clippers to come out with urgency, intensity, and a heightened focus on taking care of the ball and executing in the clutch—because their path to advancement starts with stealing one on the road, and Game 2 is their best shot.

The Denver Nuggets and Los Angeles Clippers clash in Game 2 of their Western Conference first-round playoff series on April 21, 2025, at Ball Arena in Denver. The Nuggets lead the series 1–0 after a thrilling 112–110 overtime victory in Game 1. Los Angeles Clippers vs Denver AI Prediction: Free NBA Betting Insights for Apr 21. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Denver Nuggets NBA Preview

The Denver Nuggets enter Game 2 of their Western Conference first-round playoff series against the Los Angeles Clippers with a hard-earned 1–0 series lead after a dramatic 112–110 overtime victory in Game 1 at Ball Arena. While the win showcased the poise and championship mettle that defined their 2023 title run, it also highlighted areas that need tightening if the Nuggets hope to put a firmer grip on this series. Nikola Jokić was predictably magnificent, finishing with 29 points, 12 assists, and 9 rebounds, dictating the offense with surgical precision and making plays both as a scorer and facilitator. Jamal Murray added 24 points and several timely buckets down the stretch, but the game turned into a grind—one where Denver’s ability to execute in the half-court and remain composed under pressure ultimately proved decisive. Despite holding home-court advantage, the Nuggets found themselves down late in regulation and needed every bit of clutch execution and defensive resolve to push the game into overtime and eventually close it out. Coach Michael Malone has emphasized postgame that while the win is valuable, the defensive breakdowns, late rotations, and inefficient perimeter shooting must be corrected if Denver wants to protect its home floor again in Game 2. One of the biggest concerns for Denver remains their defense, which ranked in the bottom third of the league post-All-Star break and showed signs of vulnerability in Game 1. The Clippers generated quality looks throughout the game, particularly when the Nuggets were slow to rotate or allowed Kawhi Leonard and James Harden to get downhill.

While Jokić held his own in post coverage and on the glass, Denver struggled at times with screen navigation and transition defense—areas that will be heavily emphasized during film sessions ahead of Game 2. Offensively, while Jokić and Murray continue to shine, the Nuggets need more consistent production from Michael Porter Jr., whose shooting can stretch defenses but who sometimes fades from games when he isn’t getting touches early. Aaron Gordon and Kentavious Caldwell-Pope will be key on both ends—they’ll need to rebound effectively, hit open looks, and provide the kind of two-way grit that elevates the supporting cast around Jokić. The bench, led by Christian Braun and Reggie Jackson, provided valuable minutes in Game 1, but Denver will need more consistent contributions from its second unit to ease the burden on the starters, especially in the minutes where Jokić rests. Despite their 26–15 home ATS record during the regular season, Denver has stumbled against the spread of late, going 7–16 ATS since March 1, indicating some underperformance relative to betting expectations. That said, playoff basketball is a different animal, and the Nuggets’ championship core understands how to make adjustments, raise the intensity, and execute under pressure. Game 2 offers Denver a chance not just to go up 2–0 in the series, but to reestablish its dominance at Ball Arena and send a clear message that the path to the Western Conference Finals still runs through the Mile High City. If they can cut down on live-ball turnovers, force the Clippers into isolation-heavy sets, and continue controlling the tempo through Jokić’s methodical orchestration, the Nuggets will be well-positioned to take full command before the series shifts to Los Angeles. In a series that’s already proven to be a tightly contested chess match, Denver’s blend of experience, discipline, and star power will need to shine once more under the playoff lights.

Los Angeles Clippers vs. Denver Prop Picks (AI)

Remi is pouring through mountains of stats on each line. In fact, anytime the Clippers and Nuggets play there’s always several intriguing angles to key in on. Not to mention games played at Ball Arena in Apr can often follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: C. Braun over 14.5 PTS+AST.

Los Angeles Clippers vs. Denver Prediction (AI)

Remi Robot Icon

Remi, our AI sports wizard, has been pouring over tons of data from every simulation between the Clippers and Nuggets and using recursive machine learning and kick-ass AI to analyze the data to a single cover probability.

Oddly enough, we’ve seen the AI has been most focused on the growing factor knucklehead sportsbettors often put on coaching factors between a Clippers team going up against a possibly unhealthy Nuggets team. It appears the true game analytics appear to reflect a slight lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our NBA AI picks for FREE now.

Below is our current AI Los Angeles Clippers vs Denver picks, computer picks Clippers vs Nuggets, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
NBA 11/8 POR@MIA UNLOCK THIS PICK 7 VAULT v3 Locked VAULT v3
NBA 11/8 LAL@ATL UNLOCK THIS PICK 6 VAULT v2 Locked VAULT v2
NBA 11/8 IND@DEN UNLOCK THIS PICK 0 INTEL Locked INTEL
NBA 11/8 CHI@CLE UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NBA schedule.

Clippers Betting Trends

The Clippers have struggled against the spread (ATS) on the road, with a 19–22 ATS record during the regular season.

Nuggets Betting Trends

The Nuggets have been inconsistent at home, posting a 26–15 ATS record during the regular season.

Clippers vs. Nuggets Matchup Trends

The Nuggets have gone 7–16 ATS since March 1, including their Game 1 performance, indicating a recent trend of underperforming against the spread. 

Los Angeles Clippers vs. Denver Game Info

Los Angeles Clippers vs Denver starts on April 21, 2025 at 10:00 PM EST.

Spread: Denver +1.5
Moneyline: Los Angeles Clippers -119, Denver -100
Over/Under: 218

Los Angeles Clippers: (50-32)  |  Denver: (50-32)

Remi's searched hard and found the best prop for this matchup: C. Braun over 14.5 PTS+AST.. Prices move—always shop for the best number.

The Nuggets have gone 7–16 ATS since March 1, including their Game 1 performance, indicating a recent trend of underperforming against the spread. 

LAC trend: The Clippers have struggled against the spread (ATS) on the road, with a 19–22 ATS record during the regular season.

DEN trend: The Nuggets have been inconsistent at home, posting a 26–15 ATS record during the regular season.

See our latest NBA picks and odds pages for 2025 to compare prices before you bet.

Los Angeles Clippers vs. Denver Odds

AI algorithm Remi is pouring through tons of data points on each line. In fact, anytime the Los Angeles Clippers vs Denver trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme altitude can often follow normal, predictable betting trends.

Los Angeles Clippers vs Denver Opening Odds

LAC Moneyline: -119
DEN Moneyline: -100
LAC Spread: -1.5
DEN Spread: +1.5
Over/Under: 218

Los Angeles Clippers vs Denver Live Odds

Games PTS ML SPR O/U
Nov 9, 2025 3:30PM EST
Houston Rockets
Milwaukee Bucks
11/9/25 3:30PM
Rockets
Bucks
-160
+141
-4 (-106)
+4 (-106)
O 232 (-102)
U 232 (-113)
Nov 9, 2025 6:00PM EST
Brooklyn Nets
New York Knicks
11/9/25 6PM
Nets
Knicks
+757
-1126
+15.5 (-106)
-15.5 (-106)
O 229.5 (-102)
U 229.5 (-113)
Nov 9, 2025 6:10PM EST
Oklahoma City Thunder
Memphis Grizzlies
11/9/25 6:10PM
Thunder
Grizzlies
-525
+400
-11 (-108)
+11 (-112)
O 234 (-110)
U 234 (-110)
Nov 9, 2025 6:10PM EST
Boston Celtics
Orlando Magic
11/9/25 6:10PM
Celtics
Magic
+140
-160
+3.5 (-115)
-3.5 (-105)
O 226.5 (-110)
U 226.5 (-110)
Nov 9, 2025 7:30PM EST
Detroit Pistons
Philadelphia 76ers
11/9/25 7:30PM
Pistons
76ers
-154
+134
-3.5 (-110)
+3.5 (-110)
O 232.5 (-105)
U 232.5 (-115)
Nov 9, 2025 8:40PM EST
Indiana Pacers
Golden State Warriors
11/9/25 8:40PM
Pacers
Warriors
+533
-713
+13 (-106)
-13 (-106)
O 227.5 (-102)
U 227.5 (-113)
Nov 9, 2025 9:10PM EST
Minnesota Timberwolves
Sacramento Kings
11/9/25 9:10PM
Timberwolves
Kings
-214
+185
-5.5 (-106)
+5.5 (-106)
O 234.5 (-113)
U 234.5 (-102)
Dec 25, 2025 12:00PM EST
Cleveland Cavaliers
New York Knicks
12/25/25 12PM
Cavaliers
Knicks
+117
-143
+2.5 (-113)
-2.5 (-113)
O 229.5 (-113)
U 229.5 (-113)
Dec 25, 2025 5:00PM EST
Dallas Mavericks
Golden State Warriors
12/25/25 5PM
Mavericks
Warriors
+150
-195
+4.5 (-112)
-4.5 (-114)
O 227 (-115)
U 227 (-110)
Dec 25, 2025 10:30PM EST
Minnesota Timberwolves
Denver Nuggets
12/25/25 10:30PM
Timberwolves
Nuggets
+175
-220
+5 (-109)
-5 (-117)
O 229.5 (-112)
U 229.5 (-114)

NBA Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Los Angeles Clippers Clippers vs. Denver Nuggets on April 21, 2025 at Ball Arena.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our NBA odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
DAL@MEM MEM -4 56.3% 6 WIN
TOR@ATL TOR +118 48.0% 3 WIN
CHA@MIA OVER 235.5 54.3% 3 LOSS
LAC@PHX PHX -135 58.9% 7 WIN
PHI@CLE PHI +10.5 53.3% 3 LOSS
MIA@DEN MIA +9.5 53.7% 3 LOSS
OKC@POR POR +4.5 52.9% 3 WIN
HOU@MEM MEM +8.5 54.7% 4 LOSS
UTA@DET UTA +10 56.8% 6 LOSS
NO@DAL TREY MURPHY III OVER 25.5 PTS & REB 55.5% 5 LOSS
ORL@ATL ORL -3.5 56.5% 6 LOSS
MIL@TOR MIL +3.5 56.5% 4 LOSS
PHX@GS STEPH CURRY UNDER 4.5 THREE PTRS MADE 53.3% 3 LOSS
OKC@LAC JAMES HARDEN OVER 12.5 REBOUNDS + ASSTS 56.1% 6 LOSS
LAL@POR POR -2.5 54.7% 4 LOSS
SA@PHX SA -5.5 56.6% 6 LOSS
ORL@WAS WAS +9 54.2% 4 LOSS
DAL@DET DAL +8 58.7% 8 LOSS
NY@CHI NY -4.5 54.7% 4 LOSS
BOS@PHI BOS +1.5 54.6% 4 WIN
TOR@CLE TOR +6 56.2% 6 WIN
DEN@POR JERAMI GRANT OVER 1.5 TURNOVERS 56.6% 6 WIN
WAS@OKC WAS +15.5 54.9% 4 LOSS
NO@DEN DEN -12.5 53.6% 3 WIN
NO@DEN NIKOLA JOKIC OVER 26.5 POINTS 56.6% 6 LOSS
SAC@OKC SAC +10 54.7% 4 WIN
NY@MIL MIL +3 56.6% 6 WIN
LAC@GS GS +2.5 56.8% 6 WIN
LAC@GS BRANDIN PODZIEMSKI UNDER 1.5 THREE POINTERS MADE 55.5% 5 LOSS
CLE@DET DET +2.5 53.5% 3 LOSS
ORL@PHI ORL -5 54.7% 4 LOSS
OKC@DAL DAL +9 66.4% 6 WIN
BOS@NO NO +2 55.6% 5 LOSS
BKN@HOU BKN +16.5 57.0% 7 LOSS
BOS@NO TREY MURPHY III UNDER 25.5 PTS + REB 54.4% 4 WIN
MIL@CLE MIL +6.5 56.1% 6 WIN
POR@LAC POR +8.5 56.5% 6 WIN
ATL@ORL ATL +5 54.6% 4 WIN
WAS@DAL WAS +10 55.3% 5 WIN
PHX@LAC IVICA ZUBAC OVER 6.5 MADE FIELD GOALS 55.5% 5 LOSS
OKC@IND IND +8 56.5% 6 WIN
CLE@NY CLE -116 55.0% 4 LOSS
LAC@UTA UTA +9.5 54.1% 4 WIN
WAS@MIL KYLE KUZMA OVER 1.5 ASSTS 55.5% 5 WIN
HOU@OKC HOU +6.5 54.8% 4 WIN
GS@LAL STEPHEN CURRY UNDER 2.5 TURNOVERS 54.4 4 WIN
IND@OKC SHAI GILGEOUS-ALEXANDER OVER 1.5 STEALS 54.90% 4 LOSS
IND@OKC JALEN WILLIAMS OVER 0.5 1Q REBOUNDS 55.70% 5 WIN
OKC@IND TJ MCCONNELL UNDER 7.5 TWO POINT ATT 55.70% 5 LOSS
IND@OKC CHET HOLMGREN OVER 1.5 SHOTS BLOCKED 53.40% 3 WIN
OKC@IND TJ MCCONNELL OVER 1.5 TURNOVERS 53.00% 3 LOSS