Clippers vs Nuggets Prediction — AI Finds CAN'T MISS NBA Lines & Props (Apr 21)
Updated: 2025-04-19T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Denver Nuggets and Los Angeles Clippers clash in Game 2 of their Western Conference first-round playoff series on April 21, 2025, at Ball Arena in Denver. The Nuggets lead the series 1–0 after a thrilling 112–110 overtime victory in Game 1.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.
GAME INFO
Date: Apr 21, 2025
Start Time: 10:00 PM EST
Venue: Ball Arena
Nuggets Record: (50-32)
Clippers Record: (50-32)
OPENING ODDS
LAC Moneyline: -119
DEN Moneyline: -100
LAC Spread: -1.5
DEN Spread: +1.5
Over/Under: 218
LAC
Betting Trends
- The Clippers have struggled against the spread (ATS) on the road, with a 19–22 ATS record during the regular season.
DEN
Betting Trends
- The Nuggets have been inconsistent at home, posting a 26–15 ATS record during the regular season.
MATCHUP TRENDS
- The Nuggets have gone 7–16 ATS since March 1, including their Game 1 performance, indicating a recent trend of underperforming against the spread. 
LAC vs. DEN
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: C. Braun over 14.5 PTS+AST.
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Los Angeles Clippers vs Denver Prediction & Odds:
Free NBA Betting Insights for 4/21/25
Where the Clippers will need to adjust is on the glass and in transition defense—two areas where Denver repeatedly found extra opportunities. Meanwhile, Denver knows that despite winning Game 1, they cannot afford complacency. Their 7–16 ATS record since March 1 suggests some struggles in meeting expectations, and with the Clippers hungry to even the series, head coach Michael Malone will need to reinforce focus on limiting second-chance points and reducing defensive lapses on high pick-and-rolls involving Leonard and George. Game 2 promises to be another tightly contested affair with high-intensity possessions, strategic adjustments, and pressure mounting on both sides. If Denver can continue to capitalize on their home-court advantage—where they’ve gone 26–15 ATS this season—and execute their offense with the fluidity they displayed in overtime, they’ll be well-positioned to take a 2–0 lead. On the other hand, if the Clippers cut down their turnovers, get more consistent scoring from their bench, and receive a bounce-back performance from George, they have more than enough firepower and playoff experience to even the series before heading back to Los Angeles. With both teams showing flashes of brilliance and areas for growth, Game 2 could set the tone for what’s shaping up to be one of the most competitive first-round series in the Western Conference. Expect physical play, deliberate pacing, and an atmosphere charged with playoff intensity as the Nuggets look to hold serve at home and the Clippers aim to punch back.
UNO climbing the #NBAPlayoffs history books with 1,072 assists 📈
— LA Clippers (@LAClippers) April 21, 2025
With 11 assists in Game 1, James Harden surpassed Larry Bird for 8th place on the @NBA’s all-time playoff assists list!@CoorsLight | #ClipperNation pic.twitter.com/sCpWvdF4TW
Los Angeles Clippers Clippers NBA Preview
The Los Angeles Clippers enter Game 2 of their Western Conference first-round playoff series against the Denver Nuggets looking to bounce back from a narrow 112–110 overtime loss in Game 1—a contest that showcased their defensive intensity, physicality, and playoff-tested poise but ultimately exposed critical late-game execution flaws. Kawhi Leonard led the way with 28 points and 9 rebounds, but his uncharacteristic 7 turnovers loomed large, particularly in crunch time where decision-making and ball security are non-negotiable. Despite the result, the Clippers’ performance gave them reasons for optimism, as they held the lead late in regulation, executed a defensive game plan that largely kept Denver’s shooters in check, and saw Ivica Zubac battle Nikola Jokić effectively in the paint. Zubac’s ability to stay vertical, protect the rim, and rebound through contact allowed L.A. to keep the rebounding battle close, while Terance Mann, James Harden, and Russell Westbrook each had moments of impact on both ends. However, 20 team turnovers and some stagnant offensive possessions down the stretch prevented them from closing the door on a potential road upset. Head coach Tyronn Lue will now challenge his team to stay sharp, clean up careless mistakes, and bring the same physical edge into Game 2—but with better control and execution under pressure. Offensively, the Clippers will need more from Paul George, who was unusually quiet in Game 1, particularly late in the fourth quarter and into overtime when his scoring and perimeter shot-making were needed most. George’s ability to create off the dribble and knock down contested jumpers can alleviate some of the pressure on Leonard, who faced double-teams and constant hedging from Denver’s defense. Expect Lue to design early sets to get George going, whether through pin-down actions, pick-and-roll mismatches, or spot-up opportunities in the corner.
Meanwhile, Harden and Westbrook will need to manage the game with composure, balancing their roles as secondary scorers with the need to facilitate ball movement and keep the offense from stagnating. The Clippers’ bench remains one of the deeper units in the playoffs, and continued contributions from Norman Powell and Mason Plumlee could be critical, especially if they can outplay Denver’s second unit and win those middle-of-the-quarter stretches when the starters rest. Defensively, the Clippers were effective in forcing Denver into tough looks and limiting second-chance points, but they’ll need to stay out of foul trouble and sharpen their closeouts to keep the Nuggets’ rhythm disrupted. The mission for Los Angeles in Game 2 is simple: maintain the defensive intensity that gave them control for much of Game 1, but eliminate the self-inflicted wounds that cost them the game. With a 19–22 ATS record on the road this season, the Clippers know they must play nearly flawless basketball to pull off a win in the altitude of Ball Arena. But with playoff-tested stars, a versatile and experienced supporting cast, and the tactical acumen of Ty Lue, this team is built for adjustments and responses. Game 2 is as much about mental resilience as it is tactical execution; a win sends the series back to Los Angeles tied and full of momentum, while a loss would mean falling into a dangerous 0–2 hole against the reigning champions. Expect the Clippers to come out with urgency, intensity, and a heightened focus on taking care of the ball and executing in the clutch—because their path to advancement starts with stealing one on the road, and Game 2 is their best shot.
Credit: USA TODAY/IMAGN
Denver Nuggets NBA Preview
The Denver Nuggets enter Game 2 of their Western Conference first-round playoff series against the Los Angeles Clippers with a hard-earned 1–0 series lead after a dramatic 112–110 overtime victory in Game 1 at Ball Arena. While the win showcased the poise and championship mettle that defined their 2023 title run, it also highlighted areas that need tightening if the Nuggets hope to put a firmer grip on this series. Nikola Jokić was predictably magnificent, finishing with 29 points, 12 assists, and 9 rebounds, dictating the offense with surgical precision and making plays both as a scorer and facilitator. Jamal Murray added 24 points and several timely buckets down the stretch, but the game turned into a grind—one where Denver’s ability to execute in the half-court and remain composed under pressure ultimately proved decisive. Despite holding home-court advantage, the Nuggets found themselves down late in regulation and needed every bit of clutch execution and defensive resolve to push the game into overtime and eventually close it out. Coach Michael Malone has emphasized postgame that while the win is valuable, the defensive breakdowns, late rotations, and inefficient perimeter shooting must be corrected if Denver wants to protect its home floor again in Game 2. One of the biggest concerns for Denver remains their defense, which ranked in the bottom third of the league post-All-Star break and showed signs of vulnerability in Game 1. The Clippers generated quality looks throughout the game, particularly when the Nuggets were slow to rotate or allowed Kawhi Leonard and James Harden to get downhill.
While Jokić held his own in post coverage and on the glass, Denver struggled at times with screen navigation and transition defense—areas that will be heavily emphasized during film sessions ahead of Game 2. Offensively, while Jokić and Murray continue to shine, the Nuggets need more consistent production from Michael Porter Jr., whose shooting can stretch defenses but who sometimes fades from games when he isn’t getting touches early. Aaron Gordon and Kentavious Caldwell-Pope will be key on both ends—they’ll need to rebound effectively, hit open looks, and provide the kind of two-way grit that elevates the supporting cast around Jokić. The bench, led by Christian Braun and Reggie Jackson, provided valuable minutes in Game 1, but Denver will need more consistent contributions from its second unit to ease the burden on the starters, especially in the minutes where Jokić rests. Despite their 26–15 home ATS record during the regular season, Denver has stumbled against the spread of late, going 7–16 ATS since March 1, indicating some underperformance relative to betting expectations. That said, playoff basketball is a different animal, and the Nuggets’ championship core understands how to make adjustments, raise the intensity, and execute under pressure. Game 2 offers Denver a chance not just to go up 2–0 in the series, but to reestablish its dominance at Ball Arena and send a clear message that the path to the Western Conference Finals still runs through the Mile High City. If they can cut down on live-ball turnovers, force the Clippers into isolation-heavy sets, and continue controlling the tempo through Jokić’s methodical orchestration, the Nuggets will be well-positioned to take full command before the series shifts to Los Angeles. In a series that’s already proven to be a tightly contested chess match, Denver’s blend of experience, discipline, and star power will need to shine once more under the playoff lights.
On to the next pic.twitter.com/tY6kq0dPK5
— Denver Nuggets (@nuggets) April 21, 2025
Los Angeles Clippers vs. Denver Prop Picks (AI)
Los Angeles Clippers vs. Denver Prediction (AI)
Remi, our AI sports wizard, has been pouring over tons of data from every simulation between the Clippers and Nuggets and using recursive machine learning and kick-ass AI to analyze the data to a single cover probability.
Oddly enough, we’ve seen the AI has been most focused on the growing factor knucklehead sportsbettors often put on coaching factors between a Clippers team going up against a possibly unhealthy Nuggets team. It appears the true game analytics appear to reflect a slight lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our NBA AI picks for FREE now.
Below is our current AI Los Angeles Clippers vs Denver picks, computer picks Clippers vs Nuggets, best bets, model edges, confidence ratings.
| DATE | GAME | LEAN | %WIN | UNITS | LEVEL | |
|---|---|---|---|---|---|---|
| NBA | 11/8 | POR@MIA | UNLOCK THIS PICK | 7 |
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| NBA | 11/8 | LAL@ATL | UNLOCK THIS PICK | 6 |
VAULT v2
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| NBA | 11/8 | IND@DEN | UNLOCK THIS PICK | 0 |
INTEL
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| NBA | 11/8 | CHI@CLE | UNLOCK THIS PICK | 0 |
INTEL
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NBA schedule.
Clippers Betting Trends
The Clippers have struggled against the spread (ATS) on the road, with a 19–22 ATS record during the regular season.
Nuggets Betting Trends
The Nuggets have been inconsistent at home, posting a 26–15 ATS record during the regular season.
Clippers vs. Nuggets Matchup Trends
The Nuggets have gone 7–16 ATS since March 1, including their Game 1 performance, indicating a recent trend of underperforming against the spread. 
Los Angeles Clippers vs. Denver Game Info
What time does Los Angeles Clippers vs Denver start on April 21, 2025?
Los Angeles Clippers vs Denver starts on April 21, 2025 at 10:00 PM EST.
Where is Los Angeles Clippers vs Denver being played?
Venue: Ball Arena.
What are the opening odds for Los Angeles Clippers vs Denver?
Spread: Denver +1.5
Moneyline: Los Angeles Clippers -119, Denver -100
Over/Under: 218
What are the records for Los Angeles Clippers vs Denver?
Los Angeles Clippers: (50-32) | Denver: (50-32)
What is the AI best bet for Los Angeles Clippers vs Denver?
Remi's searched hard and found the best prop for this matchup: C. Braun over 14.5 PTS+AST.. Prices move—always shop for the best number.
What are Los Angeles Clippers vs Denver trending bets?
The Nuggets have gone 7–16 ATS since March 1, including their Game 1 performance, indicating a recent trend of underperforming against the spread. 
What are Los Angeles Clippers trending bets?
LAC trend: The Clippers have struggled against the spread (ATS) on the road, with a 19–22 ATS record during the regular season.
What are Denver trending bets?
DEN trend: The Nuggets have been inconsistent at home, posting a 26–15 ATS record during the regular season.
Where can I find AI Picks for Los Angeles Clippers vs Denver?
See our latest NBA picks and odds pages for 2025 to compare prices before you bet.
Los Angeles Clippers vs. Denver Odds
AI algorithm Remi is pouring through tons of data points on each line. In fact, anytime the Los Angeles Clippers vs Denver trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme altitude can often follow normal, predictable betting trends.
Los Angeles Clippers vs Denver Opening Odds
LAC Moneyline:
-119 DEN Moneyline: -100
LAC Spread: -1.5
DEN Spread: +1.5
Over/Under: 218
Los Angeles Clippers vs Denver Live Odds
| Games | PTS | ML | SPR | O/U | |
|---|---|---|---|---|---|
|
Nov 9, 2025 3:30PM EST
Houston Rockets
Milwaukee Bucks
11/9/25 3:30PM
Rockets
Bucks
|
–
–
|
-160
+141
|
-4 (-106)
+4 (-106)
|
O 232 (-102)
U 232 (-113)
|
|
|
Nov 9, 2025 6:00PM EST
Brooklyn Nets
New York Knicks
11/9/25 6PM
Nets
Knicks
|
–
–
|
+757
-1126
|
+15.5 (-106)
-15.5 (-106)
|
O 229.5 (-102)
U 229.5 (-113)
|
|
|
Nov 9, 2025 6:10PM EST
Oklahoma City Thunder
Memphis Grizzlies
11/9/25 6:10PM
Thunder
Grizzlies
|
–
–
|
-525
+400
|
-11 (-108)
+11 (-112)
|
O 234 (-110)
U 234 (-110)
|
|
|
Nov 9, 2025 6:10PM EST
Boston Celtics
Orlando Magic
11/9/25 6:10PM
Celtics
Magic
|
–
–
|
+140
-160
|
+3.5 (-115)
-3.5 (-105)
|
O 226.5 (-110)
U 226.5 (-110)
|
|
|
Nov 9, 2025 7:30PM EST
Detroit Pistons
Philadelphia 76ers
11/9/25 7:30PM
Pistons
76ers
|
–
–
|
-154
+134
|
-3.5 (-110)
+3.5 (-110)
|
O 232.5 (-105)
U 232.5 (-115)
|
|
|
Nov 9, 2025 8:40PM EST
Indiana Pacers
Golden State Warriors
11/9/25 8:40PM
Pacers
Warriors
|
–
–
|
+533
-713
|
+13 (-106)
-13 (-106)
|
O 227.5 (-102)
U 227.5 (-113)
|
|
|
Nov 9, 2025 9:10PM EST
Minnesota Timberwolves
Sacramento Kings
11/9/25 9:10PM
Timberwolves
Kings
|
–
–
|
-214
+185
|
-5.5 (-106)
+5.5 (-106)
|
O 234.5 (-113)
U 234.5 (-102)
|
|
|
Dec 25, 2025 12:00PM EST
Cleveland Cavaliers
New York Knicks
12/25/25 12PM
Cavaliers
Knicks
|
–
–
|
+117
-143
|
+2.5 (-113)
-2.5 (-113)
|
O 229.5 (-113)
U 229.5 (-113)
|
|
|
Dec 25, 2025 5:00PM EST
Dallas Mavericks
Golden State Warriors
12/25/25 5PM
Mavericks
Warriors
|
–
–
|
+150
-195
|
+4.5 (-112)
-4.5 (-114)
|
O 227 (-115)
U 227 (-110)
|
|
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Dec 25, 2025 10:30PM EST
Minnesota Timberwolves
Denver Nuggets
12/25/25 10:30PM
Timberwolves
Nuggets
|
–
–
|
+175
-220
|
+5 (-109)
-5 (-117)
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O 229.5 (-112)
U 229.5 (-114)
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NBA Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Los Angeles Clippers Clippers vs. Denver Nuggets on April 21, 2025 at Ball Arena.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our NBA odds pages, and compare prices before you place a bet.
| LEAN | %WIN | UNITS | RESULT | |
|---|---|---|---|---|
| DAL@MEM | MEM -4 | 56.3% | 6 | WIN |
| TOR@ATL | TOR +118 | 48.0% | 3 | WIN |
| CHA@MIA | OVER 235.5 | 54.3% | 3 | LOSS |
| LAC@PHX | PHX -135 | 58.9% | 7 | WIN |
| PHI@CLE | PHI +10.5 | 53.3% | 3 | LOSS |
| MIA@DEN | MIA +9.5 | 53.7% | 3 | LOSS |
| OKC@POR | POR +4.5 | 52.9% | 3 | WIN |
| HOU@MEM | MEM +8.5 | 54.7% | 4 | LOSS |
| UTA@DET | UTA +10 | 56.8% | 6 | LOSS |
| NO@DAL | TREY MURPHY III OVER 25.5 PTS & REB | 55.5% | 5 | LOSS |
| ORL@ATL | ORL -3.5 | 56.5% | 6 | LOSS |
| MIL@TOR | MIL +3.5 | 56.5% | 4 | LOSS |
| PHX@GS | STEPH CURRY UNDER 4.5 THREE PTRS MADE | 53.3% | 3 | LOSS |
| OKC@LAC | JAMES HARDEN OVER 12.5 REBOUNDS + ASSTS | 56.1% | 6 | LOSS |
| LAL@POR | POR -2.5 | 54.7% | 4 | LOSS |
| SA@PHX | SA -5.5 | 56.6% | 6 | LOSS |
| ORL@WAS | WAS +9 | 54.2% | 4 | LOSS |
| DAL@DET | DAL +8 | 58.7% | 8 | LOSS |
| NY@CHI | NY -4.5 | 54.7% | 4 | LOSS |
| BOS@PHI | BOS +1.5 | 54.6% | 4 | WIN |
| TOR@CLE | TOR +6 | 56.2% | 6 | WIN |
| DEN@POR | JERAMI GRANT OVER 1.5 TURNOVERS | 56.6% | 6 | WIN |
| WAS@OKC | WAS +15.5 | 54.9% | 4 | LOSS |
| NO@DEN | DEN -12.5 | 53.6% | 3 | WIN |
| NO@DEN | NIKOLA JOKIC OVER 26.5 POINTS | 56.6% | 6 | LOSS |
| SAC@OKC | SAC +10 | 54.7% | 4 | WIN |
| NY@MIL | MIL +3 | 56.6% | 6 | WIN |
| LAC@GS | GS +2.5 | 56.8% | 6 | WIN |
| LAC@GS | BRANDIN PODZIEMSKI UNDER 1.5 THREE POINTERS MADE | 55.5% | 5 | LOSS |
| CLE@DET | DET +2.5 | 53.5% | 3 | LOSS |
| ORL@PHI | ORL -5 | 54.7% | 4 | LOSS |
| OKC@DAL | DAL +9 | 66.4% | 6 | WIN |
| BOS@NO | NO +2 | 55.6% | 5 | LOSS |
| BKN@HOU | BKN +16.5 | 57.0% | 7 | LOSS |
| BOS@NO | TREY MURPHY III UNDER 25.5 PTS + REB | 54.4% | 4 | WIN |
| MIL@CLE | MIL +6.5 | 56.1% | 6 | WIN |
| POR@LAC | POR +8.5 | 56.5% | 6 | WIN |
| ATL@ORL | ATL +5 | 54.6% | 4 | WIN |
| WAS@DAL | WAS +10 | 55.3% | 5 | WIN |
| PHX@LAC | IVICA ZUBAC OVER 6.5 MADE FIELD GOALS | 55.5% | 5 | LOSS |
| OKC@IND | IND +8 | 56.5% | 6 | WIN |
| CLE@NY | CLE -116 | 55.0% | 4 | LOSS |
| LAC@UTA | UTA +9.5 | 54.1% | 4 | WIN |
| WAS@MIL | KYLE KUZMA OVER 1.5 ASSTS | 55.5% | 5 | WIN |
| HOU@OKC | HOU +6.5 | 54.8% | 4 | WIN |
| GS@LAL | STEPHEN CURRY UNDER 2.5 TURNOVERS | 54.4 | 4 | WIN |
| IND@OKC | SHAI GILGEOUS-ALEXANDER OVER 1.5 STEALS | 54.90% | 4 | LOSS |
| IND@OKC | JALEN WILLIAMS OVER 0.5 1Q REBOUNDS | 55.70% | 5 | WIN |
| OKC@IND | TJ MCCONNELL UNDER 7.5 TWO POINT ATT | 55.70% | 5 | LOSS |
| IND@OKC | CHET HOLMGREN OVER 1.5 SHOTS BLOCKED | 53.40% | 3 | WIN |
| OKC@IND | TJ MCCONNELL OVER 1.5 TURNOVERS | 53.00% | 3 | LOSS |