Cavaliers vs. Trail Blazers
Prediction, Odds & Props
Mar 25 | NBA AI Picks

Updated: 2025-03-23T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Cleveland Cavaliers (57-14) will visit the Portland Trail Blazers (32-40) on March 25, 2025, at the Moda Center in Portland. The Cavaliers aim to extend their dominance atop the Eastern Conference, while the Trail Blazers seek to improve their standing in the Western Conference.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Mar 25, 2025

Start Time: 10:00 PM EST​

Venue: Moda Center at the Rose Quarter​

Trail Blazers Record: (32-40)

Cavaliers Record: (57-14)

OPENING ODDS

CLE Moneyline: -270

POR Moneyline: +220

CLE Spread: -6.5

POR Spread: +6.5

Over/Under: 231

CLE
Betting Trends

  • The Cavaliers have a 6-3-1 record against the spread (ATS) in their last ten games and are 20-10-1 ATS at home.

POR
Betting Trends

  • The Trail Blazers are 5-5 ATS in their previous ten games and hold a 16-13-1 ATS record on the road.

MATCHUP TRENDS

  • In their last matchup on March 2, 2025, the Cavaliers defeated the Trail Blazers 133-129 in overtime, with Cleveland covering the 11.5-point spread.

CLE vs. POR
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: E. Mobley under 33.5 Pts + Ast + Reb

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Cleveland vs Portland Prediction & Odds:
Free NBA Betting Insights for 3/25/25

The upcoming game between the Cleveland Cavaliers and the Portland Trail Blazers on March 25, 2025, at the Moda Center presents an intriguing non-conference matchup. The Cavaliers, boasting a 57-14 record, have been a dominant force in the Eastern Conference, while the Trail Blazers, with a 32-40 record, are striving to find consistency in the Western Conference. Cleveland’s success this season can be attributed to their balanced roster and exceptional performance on both ends of the court. Offensively, they rank among the league’s best, averaging 122.35 points per game, with an impressive 51.15% field goal percentage. Defensively, they allow 112.55 points per game, showcasing their ability to limit opponents effectively. Portland, on the other hand, has experienced a rollercoaster season. Offensively, they average 106.05 points per game, shooting 42.80% from the field. Defensively, they allow 113.60 points per game, indicating challenges in containing opposing offenses. The previous encounter between these teams on March 2, 2025, resulted in a thrilling 133-129 overtime victory for the Cavaliers. In that game, Cleveland’s De’Andre Hunter led with 32 points, while Deni Avdija recorded his first career triple-double with 30 points, 12 rebounds, and 10 assists. For Portland, Anfernee Simons contributed significantly, but it wasn’t enough to secure the win. From a betting perspective, the Cavaliers have been reliable against the spread (ATS), with a 6-3-1 record in their last ten games and a 20-10-1 ATS record at home.

The Trail Blazers are 5-5 ATS in their previous ten games and hold a 16-13-1 ATS record on the road. Notably, in their last matchup, Cleveland covered the 11.5-point spread. In terms of injuries, the Cavaliers have Donovan Mitchell listed as out for rest. The Trail Blazers have several players on the injury report, including Robert Williams III (out), Deni Avdija (day-to-day), Jerami Grant (day-to-day), Matisse Thybulle (out), and Deandre Ayton (out). Strategically, the Cavaliers will likely leverage their offensive efficiency and depth to exploit Portland’s defensive vulnerabilities. The Trail Blazers will need to focus on tightening their defense and finding consistent scoring options to counter Cleveland’s balanced attack. In conclusion, this matchup favors the Cavaliers, given their superior record and recent performance. However, the Trail Blazers have the potential to challenge Cleveland, especially if they can capitalize on home-court advantage and address their defensive shortcomings. Fans can anticipate a competitive game as both teams aim to assert their strengths on the court.

Cleveland Cavaliers NBA Preview

The Cleveland Cavaliers arrive in Portland on March 25, 2025, with a commanding 57–14 record, perched atop the Eastern Conference and eyeing a deep playoff run fueled by their elite two-way performance and system continuity. Under head coach J.B. Bickerstaff, the Cavaliers have emerged as one of the most efficient and well-rounded teams in the NBA this season, combining suffocating defense with one of the league’s most fluid and effective offenses. Even with All-Star guard Donovan Mitchell expected to miss this matchup for rest purposes, Cleveland remains heavily favored thanks to their exceptional depth, cohesion, and the continued emergence of a supporting cast that has stepped up in critical moments. Their recent overtime win over Portland earlier this month—133-129—showcased exactly how dangerous this Cavaliers team can be, even in high-pressure situations and without their primary scorer dominating the game. In Mitchell’s absence, much of the offensive load has fallen to Darius Garland and Evan Mobley, who have responded by elevating their playmaking and scoring impact. Garland, averaging nearly 20 points and over 7 assists per game, has taken command of the offense with poise and creativity, effortlessly navigating pick-and-rolls and exploiting defensive mismatches. His chemistry with Mobley has blossomed into one of the league’s most effective young duos. Mobley, meanwhile, has continued his trajectory as a future franchise cornerstone, delivering dominant two-way performances with improved mid-range shooting, post footwork, and help-side rim protection. Without Jarrett Allen in the paint for stretches this season, Mobley has assumed even more defensive responsibility—and has thrived under the pressure.

On the wings, De’Andre Hunter and Deni Avdija have added valuable versatility. Avdija is fresh off a triple-double performance in the last meeting with Portland and has proven to be an excellent connector in Cleveland’s offense. His ability to rebound, push the ball in transition, and make the right read has helped the Cavaliers keep their offensive tempo high and balanced. Hunter brings defensive toughness and catch-and-shoot reliability, helping Cleveland space the floor while neutralizing opposing perimeter threats. The Cavaliers also continue to benefit from strong contributions off the bench from veteran leaders like Caris LeVert and Ricky Rubio, who stabilize the second unit and offer scoring bursts when needed. Defensively, Cleveland continues to be one of the stingiest units in the NBA, giving up just over 112 points per game while holding opponents to below 47% shooting from the field. Their perimeter defense is anchored by the on-ball prowess of Garland, LeVert, and Hunter, while Mobley and Allen clean up mistakes in the paint. This defensive versatility allows Bickerstaff to switch freely, double aggressively when necessary, and trust his players to rotate with discipline and precision. Against a Portland team that struggles with efficiency and often plays short-handed, Cleveland’s defense will look to smother early, create turnovers, and convert in transition. Cleveland’s focus in this game will be sharp despite Mitchell’s rest. With the playoffs looming, every game is a chance to maintain rhythm, test rotations, and fine-tune execution. The Cavaliers know how to handle business against sub-.500 teams and will aim to control the tempo, dominate the paint, and stretch the floor through ball movement and disciplined shot selection. A win in Portland not only extends their dominance but sends another message to the rest of the league: the Cavaliers are a complete team—and they are ready to contend.

The Cleveland Cavaliers (57-14) will visit the Portland Trail Blazers (32-40) on March 25, 2025, at the Moda Center in Portland. The Cavaliers aim to extend their dominance atop the Eastern Conference, while the Trail Blazers seek to improve their standing in the Western Conference. Cleveland vs Portland AI Prediction: Free NBA Betting Insights for Mar 25. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Portland Trail Blazers NBA Preview

The Portland Trail Blazers, currently holding a 32-40 record, are preparing to host the formidable Cleveland Cavaliers at the Moda Center on March 25, 2025. This season has been marked by inconsistency for Portland, as they strive to find a rhythm in the competitive Western Conference. Despite the challenges, the Trail Blazers have shown resilience, particularly in their recent performances. Offensively, Portland averages 106.05 points per game, with a field goal percentage of 42.80%. Their three-point shooting has been a crucial component, averaging 11.55 made three-pointers per game. Anfernee Simons has been a standout performer, averaging 18.6 points and 5.0 assists per game, providing a significant boost to the team’s scoring efforts. Defensively, the Trail Blazers allow 113.60 points per game, indicating areas that require improvement. Their defensive rebounding stands at 30.45 per game, and they average 9.00 steals, showcasing their ability to disrupt opponents’ offenses. In their previous encounter with the Cavaliers on March 2, 2025, Portland demonstrated competitiveness, pushing the game into overtime before falling 133-129. This performance highlighted their potential to challenge top-tier teams, even in the absence of key players due to injuries. The Trail Blazers have faced injury problems throughout the season, which have significantly impacted their rotation and overall consistency. Deandre Ayton and Robert Williams III remain sidelined, stripping Portland of its two most reliable interior defenders and rebounders. Jerami Grant and Deni Avdija, two crucial forwards with scoring and defensive versatility, are currently listed as day-to-day, and their availability could play a major role in how competitive the Blazers can remain against Cleveland’s balanced attack. The frontcourt absences have forced head coach Chauncey Billups to experiment with smaller lineups and increased roles for players like Jabari Walker, Toumani Camara, and Duop Reath, who have shown flashes but struggle with consistency against more experienced and physically dominant opponents. In the backcourt, much of the offensive responsibility has fallen on Anfernee Simons and rookie Scoot Henderson.

Simons continues to be the team’s most dependable scoring option, using his quick first step, crafty finishing, and streaky outside shooting to spark runs. Henderson, while still acclimating to the NBA’s pace, has gradually found more confidence as a primary ball-handler and playmaker. His athleticism and aggressiveness offer glimpses of a potential future star, but his shot selection and decision-making remain areas for growth. Still, these developmental minutes are vital for Portland’s long-term rebuild, and games against high-level competition like Cleveland provide invaluable learning experiences for their young core. Despite their sub-.500 record, the Blazers have shown they can compete when they shoot the ball well and defend with effort. The overtime battle with Cleveland earlier this month is a prime example. In that game, the Blazers nearly pulled off the upset despite missing several key players. Their ability to move the ball (assisting on 27 of their made baskets), attack the rim, and get to the line kept them competitive throughout. Against a Cavaliers team ranked among the league’s best on both ends, Portland will need to replicate that formula—protecting the basketball, rotating well defensively, and finding hot hands from three-point range. Portland’s home-court advantage may also play a subtle role. While their record at the Moda Center isn’t elite, they have managed several key wins in front of their home crowd, often feeding off the energy to push through dry spells or come back from double-digit deficits. For a team as young and undermanned as Portland, energy and morale can shift quickly—and Billups has done a commendable job keeping his players engaged and competitive despite limited playoff hopes. This game provides Portland an opportunity to test its progress and continue evaluating its evolving roster. While the odds are stacked against them, especially given Cleveland’s record and form, the Trail Blazers have enough firepower and youth-driven energy to make this a closer game than expected—particularly if their wings are healthy and their guards can control the pace. The results may not define their season, but the fight, effort, and internal development on display could offer further clarity on which pieces of this young roster belong in the franchise’s future plans.

Cleveland vs. Portland Prop Picks (AI)

AI algorithm Remi is pouring through loads of data on each line. In fact, anytime the Cavaliers and Trail Blazers play there’s always several intriguing trends to key in on. Not to mention games played at Moda Center at the Rose Quarter in Mar can often follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: E. Mobley under 33.5 Pts + Ast + Reb

Cleveland vs. Portland Prediction (AI)

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Remi, our AI sports algorithm, has been pouring over millions of data from every past game between the Cavaliers and Trail Blazers and using recursive machine learning and impressive AI to boil down the data to a single cover probability.

Remi has been most keyed in on the trending weight human bettors regularly put on coaching factors between a Cavaliers team going up against a possibly improved Trail Blazers team. Trends look to say the true game analytics appear to reflect a moderate lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our NBA AI picks for FREE now.

Below is our current AI Cleveland vs Portland picks, computer picks Cavaliers vs Trail Blazers, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NBA schedule.

Cavaliers Betting Trends

The Cavaliers have a 6-3-1 record against the spread (ATS) in their last ten games and are 20-10-1 ATS at home.

Trail Blazers Betting Trends

The Trail Blazers are 5-5 ATS in their previous ten games and hold a 16-13-1 ATS record on the road.

Cavaliers vs. Trail Blazers Matchup Trends

In their last matchup on March 2, 2025, the Cavaliers defeated the Trail Blazers 133-129 in overtime, with Cleveland covering the 11.5-point spread.

Cleveland vs. Portland Game Info

Cleveland vs Portland starts on March 25, 2025 at 10:00 PM EST.

Venue: Moda Center at the Rose Quarter.

Spread: Portland +6.5
Moneyline: Cleveland -270, Portland +220
Over/Under: 231

Cleveland: (57-14)  |  Portland: (32-40)

Remi's searched hard and found the best prop for this matchup: E. Mobley under 33.5 Pts + Ast + Reb. Prices move—always shop for the best number.

In their last matchup on March 2, 2025, the Cavaliers defeated the Trail Blazers 133-129 in overtime, with Cleveland covering the 11.5-point spread.

CLE trend: The Cavaliers have a 6-3-1 record against the spread (ATS) in their last ten games and are 20-10-1 ATS at home.

POR trend: The Trail Blazers are 5-5 ATS in their previous ten games and hold a 16-13-1 ATS record on the road.

See our latest NBA picks and odds pages for 2025 to compare prices before you bet.

Cleveland vs. Portland Odds

AI algorithm Remi is pouring through loads of data points on each line. In fact, anytime the Cleveland vs Portland trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme hostile environments seemingly never follow normal, predictable betting trends.

Cleveland vs Portland Opening Odds

CLE Moneyline: -270
POR Moneyline: +220
CLE Spread: -6.5
POR Spread: +6.5
Over/Under: 231

Cleveland vs Portland Live Odds

Games PTS ML SPR O/U
Oct 21, 2025 7:30PM EDT
Houston Rockets
Oklahoma City Thunder
10/21/25 7:30PM
Rockets
Thunder
+230
-305
+7.5 (-114)
-7.5 (-112)
O 225.5 (-114)
U 225.5 (-112)
Oct 21, 2025 10:00PM EDT
Golden State Warriors
Los Angeles Lakers
10/21/25 10PM
Warriors
Lakers
+135
-167
+3.5 (-112)
-3.5 (-114)
O 224.5 (-112)
U 224.5 (-114)
Oct 22, 2025 7:10PM EDT
Brooklyn Nets
Charlotte Hornets
10/22/25 7:10PM
Nets
Hornets
+145
-182
+4 (-115)
-4 (-110)
O 221 (-113)
U 221 (-113)
Oct 22, 2025 7:10PM EDT
Cleveland Cavaliers
New York Knicks
10/22/25 7:10PM
Cavaliers
Knicks
+145
-182
+4 (-114)
-4 (-112)
O 227.5 (-112)
U 227.5 (-114)
Oct 22, 2025 7:10PM EDT
Miami Heat
Orlando Magic
10/22/25 7:10PM
Heat
Magic
+240
-315
+7.5 (-113)
-7.5 (-113)
O 207 (-113)
U 207 (-112)
Oct 22, 2025 7:40PM EDT
Philadelphia 76ers
Boston Celtics
10/22/25 7:40PM
76ers
Celtics
+107
-132
+2 (-110)
-2 (-115)
O 221.5 (-115)
U 221.5 (-110)
Oct 22, 2025 7:40PM EDT
Toronto Raptors
Atlanta Hawks
10/22/25 7:40PM
Raptors
Hawks
+190
-245
+6 (-113)
-6 (-112)
O 236.5 (-114)
U 236.5 (-112)
Oct 22, 2025 8:10PM EDT
Washington Wizards
Milwaukee Bucks
10/22/25 8:10PM
Wizards
Bucks
+285
-385
+8.5 (-115)
-8.5 (-109)
O 225 (-110)
U 225 (-115)
Oct 22, 2025 8:10PM EDT
Detroit Pistons
Chicago Bulls
10/22/25 8:10PM
Pistons
Bulls
-132
+106
-2 (-114)
+2 (-112)
O 236.5 (-114)
U 236.5 (-112)
Oct 22, 2025 8:10PM EDT
New Orleans Pelicans
Memphis Grizzlies
10/22/25 8:10PM
Pelicans
Grizzlies
+150
-190
+4.5 (-112)
-4.5 (-113)
O 238.5 (-113)
U 238.5 (-113)
Oct 22, 2025 9:10PM EDT
Los Angeles Clippers
Utah Jazz
10/22/25 9:10PM
Clippers
Jazz
-345
+260
-8 (-113)
+8 (-112)
O 227.5 (-112)
U 227.5 (-114)
Oct 22, 2025 9:40PM EDT
San Antonio Spurs
Dallas Mavericks
10/22/25 9:40PM
Spurs
Mavericks
-113
-110
-1 (-109)
+1 (-117)
O 226.5 (-112)
U 226.5 (-113)
Oct 22, 2025 10:10PM EDT
Sacramento Kings
Phoenix Suns
10/22/25 10:10PM
Kings
Suns
-103
-121
+1.5 (-114)
-1.5 (-110)
O 229.5 (-112)
U 229.5 (-114)
Oct 22, 2025 10:10PM EDT
Minnesota Timberwolves
Portland Trail Blazers
10/22/25 10:10PM
Timberwolves
Trail Blazers
-143
+115
-2.5 (-114)
+2.5 (-112)
O 216 (-114)
U 216 (-112)
Oct 23, 2025 7:40PM EDT
Oklahoma City Thunder
Indiana Pacers
10/23/25 7:40PM
Thunder
Pacers
-323
+240
-7.5 (-110)
+7.5 (-110)
O 226.5 (-110)
U 226.5 (-110)
Oct 23, 2025 10:10PM EDT
Denver Nuggets
Golden State Warriors
10/23/25 10:10PM
Nuggets
Warriors
-109
-116
+1 (-110)
-1 (-110)
O 232.5 (-110)
U 232.5 (-110)

NBA Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Cleveland Cavaliers vs. Portland Trail Blazers on March 25, 2025 at Moda Center at the Rose Quarter.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our NBA odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
IND@OKC PASCAL SIAKAM OVER 2.5 PERSONAL FOULS 54.20% 4 WIN
IND@OKC IND +10 54.00% 3 WIN
IND@OKC BENNEDICT MATHURIN OVER 2.5 FREE THROW ATT 54.90% 4 WIN
NY@IND MYLES TURNER OVER 6 REBOUNDS + ASSTS 54.40% 4 LOSS
IND@NY IND +5 55.60% 5 LOSS
NY@IND JALEN BRUNSON UNDER 22 FIELD GOAL ATT 54.70% 4 WIN
OKC@MIN RUDY GOBERT OVER 1.5 FREE THROWS MADE 54.00% 4 WIN
OKC@MIN OKC -2.5 56.70% 6 LOSS
NY@IND KARL ANTHONY TOWNS OVER 32.5 POINTS + REBOUNDS 54.00% 4 WIN
OKC@MIN NAZ REID OVER 9.0 FIELD GOAL ATT 54.60% 4 LOSS
IND@NY MYLES TURNER OVER 5 MADE FIELD GOALS 53.60% 3 WIN
IND@NY NY -5.5 55.00% 4 LOSS
MIN@OKC ISAIAH HARTENSTEIN UNDER 7.5 REBOUNDS 53.00% 3 LOSS
MIN@OKC MIN +7.5 54.70% 4 LOSS
IND@NY TYRESE HALIBURTON ASSTS - UNDER 8.5 54.10% 4 LOSS
IND@NY IND +4.5 54.80% 4 WIN
MIN@OKC ALEX CARUSO UNDER 2.5 ASSTS 54.10% 4 WIN
DEN@OKC MICHAEL PORTER UNDER 7.5 REBS + AST 54.80% 4 WIN
BOS@NY NY -2.5 55.60% 5 WIN
GS@MIN DONTE DIVINCENZO OVER 1.5 TURNOVERS 54.80% 4 LOSS
GS@MIN GS +10.5 54.70% 4 LOSS
DEN@OKC NIKOLA JOKIC UNDER 22.5 REBOUNDS + ASSTS 54.00% 4 WIN
MIN@GS JIMMY BUTLER UNDER 33.5 POINTS + REBOUNDS 54.50% 4 WIN
BOS@NY BOS -5.5 54.70% 4 WIN
OKC@DEN OKC -5 55.70% 5 LOSS
DEN@OKC SHAI GILGEOUS-ALEXANDER UNDER 12.5 REBOUNDS + ASSTS 54.20% 4 WIN
IND@CLE IND +8 54.00% 3 WIN
GS@MIN ANTHONY EDWARDS UNDER 40.5 PTS+REB+AST 54.00% 4 WIN
GS@MIN MIN -6.5 54.40% 4 LOSS
DEN@OKC NIKOLA JOKIC UNDER 36.5 POINTS + ASSTS 53.20% 3 LOSS
IND@CLE IND +8.5 55.70% 5 WIN
HOU@GS GS -5 53.70% 3 LOSS
HOU@GS BRANDIN PODZIEMSKI UNDER 5.5 REBOUNDS 54.10% 4 LOSS
DEN@LAC MICHAEL PORTER UNDER 7.5 REBS + AST 53.20% 3 WIN
DEN@LAC UNDER 212.5 54.00% 3 LOSS
MIN@LAL MIN +6 53.80% 3 WIN
MIN@LAL NAZ REID OVER 1.5 ASSTS 54.80% 4 WIN
LAC@DEN IVICA ZUBAC OVER 1.5 TURNOVERS 53.50% 3 LOSS
DET@NY DET +5.5 53.90% 3 WIN
CLE@MIA EVAN MOBLEY UNDER 29.5 PTS+REB+AST 53.90% 3 WIN
BOS@ORL KRISTAPS PORZINGIS UNDER 8.5 REBOUNDS + ASSTS 53.10% 3 WIN
HOU@GS GS -3 53.70% 3 WIN
HOU@GS JALEN GREEN OVER 2.5 TURNOVERS 54.40% 4 LOSS
LAL@MIN LEBRON JAMES UNDER 31.5 POINTS + REBOUNDS 54.50% 4 LOSS
BOS@ORL BOS -3.5 54.70% 4 LOSS
DEN@LAC BOGDAN BOGDANOVIC OVER 2.5 THREE POINTERS ATTEMPTED 53.60% 3 LOSS
GS@HOU JALEN GREEN UNDER 3.5 FREE THROWS MADE 54.40% 4 LOSS
ORL@BOS ORL +10.5 54.70% 4 WIN
MEM@OKC ISAIAH HARTENSTEIN OVER 19.5 PTS + REB 53.80% 3 LOSS
MEM@OKC OKC -14.5 54.80% 4 WIN
LAC@DEN IVICA ZUBAC OVER 3.5 OFFENSIVE REBOUNDS 53.30% 3 LOSS