Away Team
Record 76-80
Last 5 2-3 last five
ATS 78-78 ATS
Road 31-47 road
Standings
MLB Game Preview
Schedule
First Pitch Countdown
10:35:00
Start Time 7:40 PM EST
Date September 22, 2026
Venue Wrigley Field
Where To Watch Marquee Sports Network
Where To Stream Fubo
Season Series Chicago leads 2-1.

Chicago returns home with consecutive wins and a 45-33 Wrigley record, while Miami arrives on a three-game skid. The market has also compressed the total from 7 to 6.5, sharpening every run-scoring edge.

Home Team
Record 87-69
Last 5 3-2 last five
ATS 76-80 ATS
Home 45-33 home
Analysis Updated: 6:50 AM ET
Injuries Checked: 6:45 AM ET
Odds Updated: 9:04 AM ET

Betting Snapshot

Spread
CHC -1.5
Open: CHC -1.5
Market Steady

Spread Movement

Loading line history...
Odds Updated: 9/22 9:04 AM ET
Moneyline
CHC -218
Open: CHC -220
Dog Taking Support

Moneyline Movement

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Odds Updated: 9/22 9:04 AM ET
Total
6.5
Open: 7
Total Dropping

Total Movement

Loading line history...
Odds Updated: 9/22 9:04 AM ET

Best Free Prop Pick

FREE PROP
Kyle Stowers Over 0.5 Total Bases
Happ has scored in three straight games entering this matchup, boosting Over 0.5 Runs appeal. Miami starter Janson Junk carries a 4.50 ERA into Wrigley against Chicago's top-scoring offense. With 612 plate appearances and 87 runs, Happ remains a high-volume scorer in Chicago's deep lineup.

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Odds Comparison Center

Shop for the best lines in one place.

Best Home Spread
FanDuel | CHC -1.5
Best Home Moneyline
BetOnline.ag | CHC -203
Best Over Line
FanDuel | 6.5
Best Away Spread
FanDuel | MIA +1.5
Best Away Moneyline
Bovada | MIA +185
Best Under Line
FanDuel | 6.5
Updated 9:04 AM ET
Sportsbook Spread Moneyline Total
FanDuelMIA +1.5
CHC -1.5
MIA +180
CHC -215
O 6.5
U 6.5
DraftKingsMIA +1.5
CHC -1.5
MIA +178
CHC -218
O 6.5
U 6.5
BetMGMMIA +1.5
CHC -1.5
MIA +180
CHC -220
O 6.5
U 6.5
FanaticsMIA +1.5
CHC -1.5
MIA +180
CHC -220
O 6.5
U 6.5
BovadaMIA +1.5
CHC -1.5
MIA +185
CHC -225
O 6.5
U 6.5
BetOnline.agMIA +1.5
CHC -1.5
MIA +182
CHC -203
O 6.5
U 6.5
LowVig.agMIA +1.5
CHC -1.5
MIA +182
CHC -203
O 6.5
U 6.5
MyBookie.agMIA +1.5
CHC -1.5
MIA +177
CHC -212
O 6.5
U 6.5
BetUSMIA +1.5
CHC -1.5
MIA +182
CHC -210
O 6.5
U 6.5
CaesarsMIA +1.5
CHC -1.5
MIA +181
CHC -213
O 6.5
U 6.5

Injury Report

Chicago's biggest pregame question is Alex Bregman, who is day-to-day with a left cheek injury after being struck by a foul ball. Miami has Xavier Edwards day-to-day with left thumb discomfort, while closer Pete Fairbanks is on the injured list with a right median nerve issue and Owen Caissie remains sidelined by a lumbar stress reaction.

Key Players

Miami
Otto Lopez
Batting .305 with 185 hits, 71 RBI and 32 steals this season.
Chicago
Pete Crow-Armstrong
Has 45 home runs and four homers across his last six games.

Key Matchup Edge

Chicago owns the clearest structural edge: a 45-33 home record, MLB-best 5.35 runs per game, and a +152 run differential against a Miami team that is 31-47 on the road. Even with the total falling, the Cubs can pressure Janson Junk before Miami's bullpen gets favorable matchups.

3 Things to Watch

  • Janson Junk against Chicago power
  • Alex Bregman's pregame availability
  • Ian Happ run-scoring opportunities

Betting Breakdown

Chicago has the stronger baseline profile entering this series opener. The Cubs are 87-69, 45-33 at Wrigley, and have won two straight while scoring 14 runs across their final two games in Cincinnati. Miami is 76-80 and has dropped three straight, with all three losses coming on the road in San Diego. The market has reinforced Chicago's edge, pricing the Cubs as a heavy favorite, but the more notable move is the total sliding from 7 to 6.5. That reduction raises the value of clean early innings and makes each high-leverage bullpen decision more important. Miami starter Janson Junk brings a 4.50 ERA into a difficult matchup with a Chicago offense averaging 5.35 runs per game. The Cubs also carry a +152 run differential and more late-season urgency in the playoff race. Miami can still threaten if Otto Lopez keeps reaching base, but its 31-47 road record and bullpen injuries leave less margin for error.

Miami Betting Outlook

Miami arrives at Wrigley at 76-80 after losing three straight in San Diego, dropping its road record to 31-47. The Marlins have still covered three of their last five, so the recent run-line profile is stronger than the straight-up results suggest. Otto Lopez remains the lineup's most dependable contact threat, batting .305 with 185 hits, 71 RBI and 32 steals. Janson Junk is the confirmed starter and carries a 4.50 ERA into a demanding matchup against MLB's highest-scoring offense. Miami's late-game depth is also thinner with Pete Fairbanks on the injured list, increasing the importance of keeping Junk efficient and avoiding an early multi-run deficit.

Chicago Betting Outlook

Chicago returns home at 87-69 with a 45-33 Wrigley record and consecutive wins over Cincinnati. The Cubs have covered three of their last five while continuing to lean on an offense that averages 5.35 runs per game and has produced 217 home runs. Pete Crow-Armstrong remains the biggest power threat after reaching 45 homers, including four across his last six games. Alex Bregman's day-to-day facial injury is the main lineup concern, but Chicago still has enough depth to pressure Miami across multiple innings. With the market pricing the Cubs as a heavy favorite, run-line execution and early scoring against Janson Junk become the cleaner betting checkpoints.

Latest Team Buzz

Miami Marlins vs Chicago Cubs FAQ

What is the current spread for Miami Marlins vs Chicago Cubs?

The current home spread is CHC -1.5, while the away spread is MIA +1.5.

How far has the spread moved for Miami Marlins vs Chicago Cubs?

The spread opened at CHC -1.5 and is now CHC -1.5.

What is the current moneyline for Miami Marlins vs Chicago Cubs?

The current moneyline is MIA +178 / CHC -218.

How far has the moneyline moved for Miami Marlins vs Chicago Cubs?

The moneyline opened at MIA +179 / CHC -220 and is now MIA +178 / CHC -218.

What is the current total for Miami Marlins vs Chicago Cubs?

The current total is 6.5.

How far has the total moved for Miami Marlins vs Chicago Cubs?

The total opened at 7 and is now 6.5.

Is the market taking the underdog in Miami Marlins vs Chicago Cubs?

Current market signal: Market Steady.

Is the market taking the favorite in Miami Marlins vs Chicago Cubs?

Current market signal: Dog Taking Support.

Is the total dropping for Miami Marlins vs Chicago Cubs?

Current totals signal: Total Dropping.

Is the total rising for Miami Marlins vs Chicago Cubs?

Current totals signal: Total Dropping.

Where to watch Miami Marlins vs Chicago Cubs?

You can watch this game on Marquee Sports Network. For the latest broadcast details, see Where to Watch.

Where to stream Miami Marlins vs Chicago Cubs?

You can stream this game on Fubo.

What is the best free prop bet for Miami Marlins vs Chicago Cubs?

Kyle Stowers Over 0.5 Total Bases

What is the biggest matchup edge for Miami Marlins vs Chicago Cubs?

Chicago owns the clearest structural edge: a 45-33 home record, MLB-best 5.35 runs per game, and a +152 run differential against a Miami team that is 31-47 on the road. Even with the total falling, the Cubs can pressure Janson Junk before Miami's bullpen gets favorable matchups.

REMI AI PERFORMANCE

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement. We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

Matchup Miami Marlins vs. Chicago Cubs
Game Date September 22, 2026
Venue Wrigley Field
RECENT COMPLETED PICKS

AI MLB PAST PICKS

35-16 68.6% WIN
GAME
LEAN
WIN %
UNITS
RESULT
SF@PIT
OVER 8.5
55.3%
5
WIN
TOR@CLE
TOR -115
54.6%
4
WIN
ATL@WAS
ATL -130
55.4%
4
WIN
TOR@CLE
JO ADELL OVER 0.5 HITS
55.4%
5
LOSS
SF@PIT
OVER 7.5
55.9%
5
WIN
SD@CIN
SD -126
55.0%
3
LOSS
NYM@TB
TB -130
54.9%
3
WIN
SF@PIT
JUNG HOO LEE OVER 0.5 HITS
54.2%
4
LOSS
DET@MIN
ROYCE LEWIS UNDER 0.5 RUNS
54.5%
4
LOSS
BAL@COL
BAL -121
54.7%
4
WIN
NYY@LAA
NYY -114
55.1%
5
LOSS
PHI@LAA
UNDER 8
54.7%
4
WIN
COL@ATL
UNDER 8.5
56.3%
6
WIN
BOS@NYY
BOS -112
54.8%
4
LOSS
SEA@TOR
SEA -125
54.6%
4
LOSS
SEA@TOR
GEORGE SPRINGER OVER 0.5 HITS
54.2%
4
WIN
MIA@WAS
OVER 7.5
55.3%
5
WIN
SEA@TOR
TOR -118
54.8%
4
WIN
COL@ATL
GRANT HOLMES OVER 4.5 HITS ALLOWED
54.2%
4
WIN
ARI@SF
ARI -110
54.8%
4
WIN
KC@CLE
CLE -126
54.9%
3
LOSS
ARI@SF
RAFAEL DEVERS OVER 0.5 HITS
54.2%
4
WIN
KC@TOR
KC -106
53.3%
3
WIN
LAD@ATL
ATL -109
53.5%
3
WIN
LAD@ATL
MICHAEL HARRIS II UNDER 1.5 BASES
53.2%
3
WIN
COL@WAS
OVER 8.5
55.8%
5
WIN
CLE@LAA
CLE -130
55.4%
4
WIN
CIN@SF
SAL STEWART OVER 0.5 STRIKEOUTS
54.7%
4
LOSS
KC@TOR
OVER 8.5
56.1%
6
LOSS
BAL@STL
STL -124
55.2%
5
LOSS
CLE@LAA
CLE -131
55.2%
4
WIN
TEX@CHW
EVAN CARTER OVER 0.5 HITS
54.2%
4
WIN
TEX@CHW
OVER 8.5
54.9%
4
WIN
CHC@ARI
CHC -130
55.5%
4
WIN
NYM@CHW
JARED YOUNG OVER 0.5 HITS
54.3%
4
WIN
STL@PHI
OVER 7.5
55.2%
5
WIN
WAS@MIA
OVER 8.5
55.4%
5
LOSS
LAA@TEX
EZEQUIEL DURAN OVER 0.5 HITS
54.2%
4
WIN
STL@PHI
OVER 9
55.8%
5
WIN
TB@BAL
TB -116
54.6%
4
LOSS
STL@PHI
BRANDON MARSH UNDER 0.5 RUNS
55.1%
5
LOSS
PIT@LAD
OVER 8
55.6%
5
WIN
TB@BAL
BAL -124
55.0%
4
WIN
SEA@MIL
DOMINIC CANZONE OVER 0.5 HITS
53.4%
3
WIN
NYY@BAL
UNDER 8
54.0%
4
WIN
NYY@BAL
NYY -116
54.2%
4
WIN
MIA@PHI
JUSTIN CRAWFORD OVER 0.5 HITS
54.4%
4
WIN
SD@NYM
SD -125
55.1%
5
LOSS
MIA@PHI
PHI -121
55.2%
5
WIN
TOR@TB
TAYLOR WALLS OVER 0.5 HITS
54.4%
4
WIN
TOR@TB
TB -126
55.1%
4
LOSS
Past performance is not a guarantee of future results. Picks are displayed for informational purposes only.