Chicago enters as the road favorite behind Shota Imanaga, but a brutal May skid and St. Louis' stronger ATS profile make this rivalry opener more dangerous than the moneyline suggests.
Betting Snapshot
Spread Movement
Moneyline Movement
Total Movement
Best Free Prop Pick
This page gives you one free prop. Upgrade for premium sides, totals, more props, and the full daily AI board.
Unlock Premium AI PicksOdds Comparison Center
Shop for the best lines in one place.
| Sportsbook | Spread | Moneyline | Total |
|---|---|---|---|
| FanDuel | CHC -1.5 STL +1.5 | CHC -130 STL +110 | O 8 U 8 |
| DraftKings | CHC -1.5 STL +1.5 | CHC -132 STL +110 | O 7.5 U 7.5 |
| BetMGM | CHC -1.5 STL +1.5 | CHC -130 STL +105 | O 7.5 U 7.5 |
| BetRivers | CHC -1.5 STL +1.5 | CHC -136 STL +110 | O 8 U 8 |
| Fanatics | CHC -1.5 STL +1.5 | CHC -130 STL +110 | O 7.5 U 7.5 |
| Bovada | CHC -1.5 STL +1.5 | CHC -132 STL +110 | O 7.5 U 7.5 |
| BetOnline.ag | CHC -1.5 STL +1.5 | CHC -123 STL +112 | O 8 U 8 |
| LowVig.ag | CHC -1.5 STL +1.5 | CHC -123 STL +112 | O 8 U 8 |
| MyBookie.ag | CHC -1.5 STL +1.5 | CHC -130 STL +111 | O 8 U 8 |
| BetUS | CHC -1.5 STL +1.5 | CHC -125 STL +114 | O 7.5 U 7.5 |
| Caesars | CHC -1.5 STL +1.5 | CHC -130 STL +110 | O 7.5 U 7.5 |
Injury Report
Chicago remains thin on the mound with Matthew Boyd, Edward Cabrera, Justin Steele and multiple relievers on the injured list, while Matt Shaw also limits lineup depth. St. Louis is missing outfielders Lars Nootbaar and Nathan Church, with Nootbaar nearing a possible June return but unavailable for this opener.
Key Players
Key Matchup Edge
Chicago owns the cleaner starting-pitching profile because Imanaga has missed more bats and allowed fewer baserunners than Leahy, but the Cubs' weak ATS record and shaky road form keep the price from feeling automatic. St. Louis needs traffic early before Chicago can leverage its bullpen matchups.
3 Things to Watch
- Imanaga command versus contact
- Leahy early traffic management
- Cardinals response after sweep
Betting Breakdown
The opener at Busch Stadium sets up as a form-versus-market test. Chicago brings the better overall record and a clear starting-pitching edge with Shota Imanaga, whose WHIP profile gives the Cubs a cleaner path if he gets ahead early and avoids free baserunners. The catch is that Chicago has been a poor ATS team overall, and the recent turnaround is still only two games removed from a deep offensive slide. St. Louis has been the better spread side this season, but its current form is uncomfortable after three straight low-scoring losses in Milwaukee and a 1-4 last-five stretch. The total sitting around 8 makes sense because both lineups have been inconsistent, yet Leahy's 1.58 WHIP leaves room for Chicago to build innings through walks and contact. The sharpest angle is whether St. Louis can pressure Imanaga early enough to flip the underdog script before the Cubs settle into run-prevention mode.
Chicago Betting Outlook
Chicago's case starts with Imanaga and the need to make a favorite price look justified. The Cubs are only 13-15 away from home and have been expensive to trust against the number, but their lineup finally showed signs of life after a long losing streak. Ian Happ, Michael Busch and Pete Crow-Armstrong give Chicago enough left-right balance to attack Leahy if his command wobbles. The betting concern is sustainability, because one offensive breakout does not erase a rough May or the rotation depth issues behind Imanaga.
St. Louis Betting Outlook
St. Louis is priced as a live home underdog because its ATS season has been stronger than its raw run differential. The Cardinals are just 13-13 at Busch Stadium and come in off a sweep, so the market is asking whether their spread value is real or already fading. Leahy must limit walks and early traffic, especially with Nootbaar and Church unavailable to lengthen the lineup. If St. Louis can keep the game tied into the middle innings, its underdog path improves because Chicago has not consistently separated on the road.
Latest Team Buzz
split the series. pic.twitter.com/AcSwLmCNqo
— Chicago Cubs (@Cubs) May 29, 2026
Heck of an effort, Dustin May! 🔥 pic.twitter.com/xemDxPhNVa
— St. Louis Cardinals (@Cardinals) May 27, 2026
Chicago Cubs vs St. Louis Cardinals FAQ
What is the current spread for Chicago Cubs vs St. Louis Cardinals?
The current home spread is STL +1.5, while the away spread is CHC -1.5.
How far has the spread moved for Chicago Cubs vs St. Louis Cardinals?
The spread opened at STL +1.5 and is now STL +1.5.
What is the current moneyline for Chicago Cubs vs St. Louis Cardinals?
The current moneyline is CHC -132 / STL +110.
How far has the moneyline moved for Chicago Cubs vs St. Louis Cardinals?
The moneyline opened at CHC -136 / STL +113 and is now CHC -132 / STL +110.
What is the current total for Chicago Cubs vs St. Louis Cardinals?
The current total is 7.5.
How far has the total moved for Chicago Cubs vs St. Louis Cardinals?
The total opened at 8 and is now 7.5.
Is the market taking the underdog in Chicago Cubs vs St. Louis Cardinals?
Current market signal: Market Steady.
Is the market taking the favorite in Chicago Cubs vs St. Louis Cardinals?
Current market signal: Favorite Taking Support.
Is the total dropping for Chicago Cubs vs St. Louis Cardinals?
Current totals signal: Total Dropping.
Is the total rising for Chicago Cubs vs St. Louis Cardinals?
Current totals signal: Total Dropping.
Where to watch Chicago Cubs vs St. Louis Cardinals?
You can watch this game on Marquee Sports Network. For the latest broadcast details, see Where to Watch.
Where to stream Chicago Cubs vs St. Louis Cardinals?
You can stream this game on Cardinals.TV.
What is the best free prop bet for Chicago Cubs vs St. Louis Cardinals?
Andre Pallante Under 5.5 Hits Allowed
What is the biggest matchup edge for Chicago Cubs vs St. Louis Cardinals?
Chicago owns the cleaner starting-pitching profile because Imanaga has missed more bats and allowed fewer baserunners than Leahy, but the Cubs' weak ATS record and shaky road form keep the price from feeling automatic. St. Louis needs traffic early before Chicago can leverage its bullpen matchups.
Want More AI Picks?
Subscribers unlock the full premium AI board with sides, totals, more props, and daily slate coverage.
GET FREE AI PICKS NOWTOOLS
Remi's Past Performance
AI SPORTS PICKS PRODUCTS
Hedge Meaning in Betting | 4 Obvious Times to Hedge
Learn about hedge betting to manage risk and secure profits. Understand...
What is a Push in Betting? | 3 Ways To Use To Your Advantage
Understand what a push in betting means, how it happens in...
What Does the + and – Mean in Sports Betting? | 5 Easy Tips
Learn the basics of sports betting odds, what the plus (+)...
What is a Round Robin Bet? | 4 Ways to Avoid Betting Traps
Learn how round-robin bets work, their advantages, and strategies to diversify...
What Percent of Bets to Win to be Profitable? | The 52.4% Strategy
What Percent of Sports Bets Do You Have to Win to...
Are Parlays Worth It? It Depends on 3 Surprising Factors
Are Parlays Worth It in Sports Betting? Parlays can be tempting...
MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Chicago Cubs vs. St. Louis Cardinals on May 29, 2026 at Busch Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
MLB |
LEAN | %WIN | UNITS | RESULT |
|---|---|---|---|---|
| PHI@SD | UNDER 7.5 | 56.8% | 6 | WIN |
| MIN@CHW | CHW -122 | 54.7% | 4 | WIN |
| PHI@SD | SD -106 | 55.6% | 5 | LOSS |
| TB@BAL | BAL -101 | 54.6% | 4 | WIN |
| HOU@TEX | TEX -118 | 55.7% | 5 | LOSS |
| ARI@SF | SF -128 | 55.7% | 4 | LOSS |
| TEX@LAA | LAA -125 | 56.1% | 5 | WIN |
| WAS@ATL | UNDER 8.5 | 56.9% | 6 | WIN |
| CHW@SF | SF -108 | 55.3% | 5 | WIN |
| MIN@BOS | UNDER 8.5 | 56.7% | 6 | WIN |
| TEX@LAA | TEX -125 | 54.8% | 4 | LOSS |
| NYM@MIA | MIA -107 | 56.2% | 6 | WIN |
| CHW@SF | SF -115 | 54.0% | 3 | WIN |
| MIN@BOS | BOS -115 | 55.0% | 4 | LOSS |
| PIT@TOR | PIT -135 | 55.0% | 4 | LOSS |
| NYM@MIA | MIA -110 | 56.2% | 6 | WIN |
| STL@CIN | CIN -117 | 56.1% | 6 | PUSH |
| DET@BAL | BAL -135 | 56.2% | 5 | WIN |
| ATL@MIA | ATL -124 | 54.3% | 4 | WIN |
| CLE@DET | DET -115 | 57.0% | 6 | LOSS |
| MIL@CHC | UNDER 6.5 | 56.7% | 6 | WIN |
| SF@ARI | ARI -127 | 57.3% | 6 | WIN |
| MIL@CHC | CHC -116 | 55.6% | 5 | LOSS |
| BAL@TB | TB -113 | 55.7% | 5 | WIN |
| PIT@STL | STL -111 | 55.4% | 5 | LOSS |
| LAD@SD | UNDER 8.5 | 54.9% | 4 | LOSS |
| BAL@TB | TB -106 | 55.7% | 5 | WIN |
| TEX@COL | COL -105 | 53.8% | 3 | LOSS |
| HOU@MIN | MIN -112 | 55.5% | 5 | WIN |
| ATL@MIA | MIA -108 | 54.6% | 4 | WIN |
| SF@ARI | ARI -133 | 55.6% | 4 | WIN |
| CIN@PHI | PHI -123 | 58.2% | 7 | WIN |
| NYY@NYM | NYM -104 | 54.2% | 4 | WIN |
| KC@STL | STL -108 | 55.8% | 5 | LOSS |
| KC@STL | STL -115 | 56.5% | 6 | WIN |
| TOR@DET | DET -125 | 56.3% | 5 | LOSS |
| CHC@CHW | CHW -108 | 56.6% | 6 | WIN |
| BAL@WAS | WAS -105 | 56.1% | 5 | WIN |
| BOS@ATL | UNDER 8 | 53.5% | 3 | WIN |
| MIA@TB | TB -116 | 56.0% | 5 | WIN |
| PHI@PIT | PIT -128 | 56.6% | 5 | LOSS |
| KC@STL | STL -110 | 56.0% | 6 | WIN |
| MIL@MIN | MIN -105 | 56.1% | 6 | LOSS |
| MIA@MIN | OVER 8.5 | 54.6% | 4 | WIN |
| PHI@BOS | BOS -104 | 54.7% | 4 | LOSS |
| MIA@MIN | MIN -120 | 56.3% | 6 | WIN |
| PHI@BOS | BOS -124 | 55.4% | 4 | WIN |
| DET@NYM | NYM -106 | 55.6% | 5 | WIN |
| LAA@CLE | UNDER 8.5 | 57.0% | 6 | WIN |
| MIA@MIN | MIN -106 | 54.8% | 4 | WIN |
| SD@MIL | MIL -125 | 55.5% | 5 | WIN |
