The San Francisco Giants and Detroit Tigers will meet in the finale of their three-game interleague series on Wednesday, May 28, 2025, with Detroit looking to complete a sweep and further assert its dominance in the American League Central. The Tigers enter the game with a 36-20 record, a mark that reflects one of the best starts in franchise history in recent memory, and they’ve done it through a balanced formula of quality starting pitching, opportunistic hitting, and disciplined defense. They’ve already taken the first two games of the series behind strong performances from both the lineup and their bullpen, and they’re hoping Jackson Jobe can maintain that momentum on the mound in the finale. Jobe comes into this start with a 4-1 record and a 4.06 ERA, showing flashes of his potential while working to improve consistency across outings. On the offensive side, Spencer Torkelson continues to lead the way with a .524 slugging percentage and a team-high 38 RBIs, while Riley Greene and Kerry Carpenter provide reliable production behind him, giving Detroit a steady top-to-middle order that can produce runs without needing to rely on the long ball. The Tigers’ pitching staff has been backed by one of the best bullpens in the American League this season, headlined by Will Vest and his stellar 1.44 ERA over 25 innings, offering manager A.J. Hinch late-game security in tight contests.

Across the diamond, the Giants arrive with a 31-24 record that keeps them in the thick of the National League playoff picture, but they’ve been stung in this series by a lack of timely offense and a few defensive miscues that have extended innings. Wilmer Flores has remained the offensive anchor, slugging 10 home runs with 45 RBIs to lead the team, while Heliot Ramos has impressed with a .281 batting average and solid gap-to-gap power. The Giants will send Landen Roupp to the mound for this pivotal contest, and the young right-hander has held his own with a 3.63 ERA and a 3-3 record, flashing poise in tough matchups and offering solid innings while limiting damage. San Francisco’s bullpen has had its bright moments but will need to be sharper if they’re to fend off a Tigers team that has been relentless in capitalizing on mistakes. Defensively, the Giants have committed 28 errors this year, a number that has cost them in key spots, and that margin for error must shrink if they’re to avoid a sweep on the road. From a betting angle, Detroit has excelled against the spread this season with a 64.3% cover rate and a 71.9% win rate as moneyline favorites, while San Francisco has been decent away from home with a 14-13 road record and a 56.4% ATS rate overall. This game could come down to execution in the middle innings, as both teams feature starters capable of working into the sixth or seventh frame, meaning the first bullpen slip or big two-out hit might swing the result. For the Tigers, it’s a chance to continue their impressive roll and prove their legitimacy as a top-tier AL contender, while the Giants will treat this as a must-win to stop the bleeding and recapture their rhythm before heading into the weekend slate.