Pirates vs Diamondbacks Prediction — AI Finds CAN'T MISS MLB Lines & Props (May 28)

Updated: 2025-05-26T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Arizona Diamondbacks (26–27) host the Pittsburgh Pirates (19–36) on Wednesday, May 28, 2025, at Chase Field, aiming to secure a series win. The Diamondbacks are favored with a -130 moneyline, while the Pirates are listed at +109, and the over/under is set at 7.5 runs.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: May 28, 2025

Start Time: 3:40 PM EST​

Venue: Chase Field​

Diamondbacks Record: (27-28)

Pirates Record: (20-36)

OPENING ODDS

PIT Moneyline: +109

ARI Moneyline: -130

PIT Spread: +1.5

ARI Spread: -1.5

Over/Under: 7.5

PIT
Betting Trends

  • The Pirates have a 8–17 record against the spread (ATS) on the road this season.

ARI
Betting Trends

  • The Diamondbacks hold a 24–28 ATS record for the current season.

MATCHUP TRENDS

  • The Diamondbacks have been favorites in 32 games this season, winning 17 of them (53.1%). In contrast, the Pirates have been underdogs in 37 games, securing victory in 13 (35.1%) of those matchups.

PIT vs. ARI
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: J. Naylor over 4.5 Fantasy Score.

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Pittsburgh vs Arizona Prediction & Odds:
Free MLB Betting Insights for 5/28/25

The Arizona Diamondbacks and Pittsburgh Pirates wrap up their three-game series on Wednesday, May 28, 2025, at Chase Field with both clubs headed in opposite directions and playing with very different levels of urgency. Arizona enters the game with a 26–27 record and is looking to climb back to .500 by securing a series win after dominating the Pirates 11–1 in the previous game. The Diamondbacks snapped out of a recent five-game skid with that emphatic victory, showcasing the depth of their offense and flashing the kind of potential that made them a playoff contender just a season ago. Ketel Marte and Corbin Carroll have led the way for Arizona all season, combining speed, power, and consistency in the heart of the lineup, while complementary pieces like Christian Walker and Gabriel Moreno have provided timely production. The Diamondbacks’ offense currently ranks seventh in team batting average and has shown the ability to put up runs in bunches when their lineup clicks. On the mound, Arizona’s starting pitching has been hit-or-miss, but the bullpen has remained a stabilizing force late in games, allowing them to close out tight matchups when given a lead. Their defensive play has also been a bright spot, limiting errors and helping support a pitching staff that leans on ground balls and defensive positioning. For Pittsburgh, the outlook continues to worsen as they enter the finale with a 19–36 record, having lost six of their last ten and suffering from one of the least productive offenses in all of baseball.

The Pirates began the season with modest optimism, but injuries, inconsistency at the plate, and unreliable pitching have derailed their momentum. While players like Oneil Cruz and Bryan Reynolds have had moments of individual brilliance, they haven’t received consistent support from the rest of the lineup, which continues to rank near the bottom of the league in key categories like batting average, OPS, and runs scored. Pittsburgh’s starting rotation has struggled to pitch deep into games, and the bullpen has been overused and exposed, particularly on the road where the Pirates have a dismal 8–17 ATS record. Defensively, the team has made too many mental and physical errors that compound in close games, turning winnable situations into mounting deficits. From a betting standpoint, the Diamondbacks have been favorites in 32 games this season and won 17 (53.1%), while the Pirates have only managed 13 wins in 37 games as underdogs (35.1%), underscoring the disparity in performance and expectations. Wednesday’s contest gives Arizona a prime opportunity to finish the homestand on a high note, keep pace in the NL West, and take advantage of a team clearly in rebuilding mode and struggling to find its footing. For the Pirates, the game represents a chance to show some fight, avoid the sweep, and perhaps spark some much-needed confidence heading into the next series. All signs point to Arizona having the upper hand, but baseball’s unpredictability means Pittsburgh can’t be completely counted out—though it would take a near-perfect performance in all phases to flip the script.

Pittsburgh Pirates MLB Preview

The Pittsburgh Pirates enter Wednesday’s series finale against the Arizona Diamondbacks desperately searching for a spark to halt a brutal stretch of baseball that has seen them fall to 19–36 and fade from relevance in the National League playoff picture. After dropping the previous game 11–1 in a lopsided affair, the Pirates have now lost six of their last ten and look like a team without answers on either side of the ball, as offensive inconsistency, pitching depth issues, and defensive breakdowns continue to define their 2025 campaign. Despite early-season optimism built around young stars and a promising farm system, Pittsburgh’s offense has sputtered badly, ranking near the bottom of the league in batting average, on-base percentage, and runs scored. Oneil Cruz, one of the few bright spots, has showcased his power and arm strength but has also struggled with strikeouts and plate discipline, while Bryan Reynolds has continued to provide steady production yet without the kind of lineup support needed to make a broader impact. The Pirates have lacked the ability to string together rallies, and they’ve been particularly ineffective with runners in scoring position, often squandering scoring chances that could shift momentum in their favor. The starting rotation has been equally unreliable, frequently failing to pitch past the fifth inning and putting undue strain on a bullpen that has been overworked and exposed as the season progresses.

While a few bullpen arms have performed admirably under pressure, the lack of consistent leads to protect has rendered even solid relief work largely moot. On the defensive side, mental lapses and fielding errors have plagued the Pirates, particularly on the road, where they’ve posted a dismal 8–17 ATS record—a reflection of their inability to stay competitive in unfamiliar environments. The lack of veteran leadership and experienced depth has only compounded the problems, leaving manager Derek Shelton with few options to stabilize a clubhouse in need of confidence and cohesion. The pitching matchup doesn’t favor Pittsburgh either, as they’ll be forced to contend with a Diamondbacks lineup that erupted for 11 runs in the previous game and appears to be regaining its offensive rhythm after a recent slump. For the Pirates to avoid a sweep, they’ll need a quality start from the mound, clean defense, and most importantly, timely hits—something that has eluded them for much of May. A win would not salvage their season, but it could at least provide a much-needed morale boost and a reminder of what this young roster is capable of when it executes fundamentals and plays with urgency. With little to lose, the Pirates may look to shake up their lineup or give extended run to younger players looking to prove themselves, knowing that the remainder of the season will likely be more about evaluation and development than chasing the standings. A strong performance in Wednesday’s finale won’t change their trajectory overnight, but it could begin to alter the tone in a clubhouse in need of any silver lining.

The Arizona Diamondbacks (26–27) host the Pittsburgh Pirates (19–36) on Wednesday, May 28, 2025, at Chase Field, aiming to secure a series win. The Diamondbacks are favored with a -130 moneyline, while the Pirates are listed at +109, and the over/under is set at 7.5 runs. Pittsburgh vs Arizona AI Prediction: Free MLB Betting Insights for May 28. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Arizona Diamondbacks MLB Preview

The Arizona Diamondbacks return to Chase Field on Wednesday looking to close out their three-game series against the Pittsburgh Pirates with a much-needed series win and the opportunity to climb back to .500 after an inconsistent May. Sitting at 26–27, the Diamondbacks snapped a frustrating five-game losing streak in emphatic fashion Tuesday night with an 11–1 dismantling of the Pirates, showcasing the type of offensive potential that made them a playoff team a year ago. Ketel Marte continues to lead the charge for Arizona, delivering quality at-bats and power from both sides of the plate, while Corbin Carroll remains a game-changer at the top of the lineup with his speed, contact ability, and defensive range in the outfield. That duo, combined with the steady presence of Christian Walker and breakout potential from young contributors like Gabriel Moreno and Blaze Alexander, has formed a core that can create runs in multiple ways—through power, stolen bases, and situational hitting. Despite their mid-month skid, the D-backs have maintained a top-10 team batting average, and their lineup is showing signs of heating up again, which could not come at a better time with the division race tightening. On the mound, Arizona has found consistency through its bullpen, which has posted respectable numbers and helped preserve narrow leads, but they’ll need stronger outings from their starters to reduce the pressure on the relief corps. Wednesday’s starting pitcher will be tasked with setting the tone early and keeping a struggling Pittsburgh offense at bay while Arizona looks to apply pressure quickly and build a lead.

Defensively, the Diamondbacks have remained one of the sharper teams in the National League, playing clean baseball with strong communication and reliable glove work across the diamond, especially from veterans like Eugenio Suárez and Nick Ahmed when they’re in the lineup. Arizona has been a tough team to beat at home, benefiting from Chase Field’s dimensions and crowd energy to fuel their momentum and execute more effectively in tight spots. From a betting perspective, the D-backs have been favored in 32 games this season and won 17 of them (53.1%), and with Pittsburgh owning just 13 wins in 37 games as underdogs, Arizona holds a clear statistical edge heading into this series finale. Manager Torey Lovullo has emphasized a return to fundamentals during this stretch—quality at-bats, aggressive baserunning, and smarter bullpen usage—and the team’s response in Game 2 of the series suggests that message is resonating. With a sweep in reach, the Diamondbacks will look to jump out early, control the pace with efficient pitching, and let their offense do the heavy lifting against a Pirates team that has looked overmatched all series long. A win would push Arizona back to .500 and set a much more optimistic tone as they prepare to reenter divisional play, reinforcing their identity as a team capable of putting pressure on opponents across all nine innings.

Pittsburgh vs. Arizona Prop Picks (AI)

AI algorithm Remi is pouring through tons of datapoints on each player. In fact, anytime the Pirates and Diamondbacks play there’s always several intriguing trends to key in on. Not to mention games played at Chase Field in May almost always follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: J. Naylor over 4.5 Fantasy Score.

Pittsburgh vs. Arizona Prediction (AI)

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Remi, our AI sports algorithm, has been pouring over mountains of data from every past game between the Pirates and Diamondbacks and using recursive machine learning and cutting-edge AI to crunch the data to a single cover probability.

The Algorithm has been most fixated on the linear correlation of emphasis knucklehead sportsbettors tend to put on player performance factors between a Pirates team going up against a possibly unhealthy Diamondbacks team. In reality, the true game analytics might reflect a slight lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI Pittsburgh vs Arizona picks, computer picks Pirates vs Diamondbacks, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
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Pirates Betting Trends

The Pirates have a 8–17 record against the spread (ATS) on the road this season.

Diamondbacks Betting Trends

The Diamondbacks hold a 24–28 ATS record for the current season.

Pirates vs. Diamondbacks Matchup Trends

The Diamondbacks have been favorites in 32 games this season, winning 17 of them (53.1%). In contrast, the Pirates have been underdogs in 37 games, securing victory in 13 (35.1%) of those matchups.

Pittsburgh vs. Arizona Game Info

Pittsburgh vs Arizona starts on May 28, 2025 at 3:40 PM EST.

Spread: Arizona -1.5
Moneyline: Pittsburgh +109, Arizona -130
Over/Under: 7.5

Pittsburgh: (20-36)  |  Arizona: (27-28)

Remi's searched hard and found the best prop for this matchup: J. Naylor over 4.5 Fantasy Score.. Prices move—always shop for the best number.

The Diamondbacks have been favorites in 32 games this season, winning 17 of them (53.1%). In contrast, the Pirates have been underdogs in 37 games, securing victory in 13 (35.1%) of those matchups.

PIT trend: The Pirates have a 8–17 record against the spread (ATS) on the road this season.

ARI trend: The Diamondbacks hold a 24–28 ATS record for the current season.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Pittsburgh vs. Arizona Odds

Remi is pouring through tons of stats on each team. In fact, anytime the Pittsburgh vs Arizona trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme travel distance rarely follow normal, predictable patterns.

Pittsburgh vs Arizona Opening Odds

PIT Moneyline: +109
ARI Moneyline: -130
PIT Spread: +1.5
ARI Spread: -1.5
Over/Under: 7.5

Pittsburgh vs Arizona Live Odds

Games PTS ML SPR O/U
Oct 19, 2025 8:04PM EDT
Seattle Mariners
Toronto Blue Jays
10/19/25 8:04PM
Mariners
Blue Jays
+105
-125
+1.5 (-205)
-1.5 (+170)
O 7.5 (-115)
U 7.5 (-105)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Pittsburgh Pirates vs. Arizona Diamondbacks on May 28, 2025 at Chase Field.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
TOR@SEA OVER 7 54.9% 3 WIN
LAD@MIL UNDER 7.5 56.6% 6 WIN
TOR@NYY OVER 8 54.9% 4 WIN
TOR@NYY CARLOS RODON OVER 1.5 TOTAL WALKS ALLOWED 53.3% 3 WIN
NYY@TOR OVER 7.5 54.8% 2 WIN
LAD@PHI OVER 7 53.8% 3 WIN
SD@CHC CHC -109 53.8% 3 WIN
SD@CHC OVER 7.5 54.5% 4 LOSS
SD@CHC CHC -111 54.8% 4 LOSS
CIN@LAD SHOHEI OHTANI OVER 1.5 BASES 53.5% 3 WIN
BOS@NYY OVER 7 53.8% 3 LOSS
CIN@LAD ELLY DE LA CRUZ OVER 0.5 BASES 54.4% 4 LOSS
ARI@SD SD -131 57.3% 4 WIN
DET@BOS BOS -115 56.4% 5 WIN
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN