Giants vs Tigers Prediction — AI Finds CAN'T MISS MLB Lines & Props (May 26)
Updated: 2025-05-24T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The San Francisco Giants (31–22) visit Comerica Park to face the Detroit Tigers (34–20) on May 26, 2025, in a compelling interleague matchup between two playoff-contending teams. The Giants aim to close the gap in the NL West, while the AL Central-leading Tigers look to maintain their division lead.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.
GAME INFO
Date: May 26, 2025
Start Time: 1:10 PM EST
Venue: Comerica Park
Tigers Record: (34-20)
Giants Record: (31-22)
OPENING ODDS
SF Moneyline: -106
DET Moneyline: -112
SF Spread: -1.5
DET Spread: +1.5
Over/Under: 8
SF
Betting Trends
- The Giants have a 24–21 record against the spread (ATS) this season, indicating a moderate performance in covering the spread. They have been consistent, with a 4–6 record in their last ten games, reflecting some variability in recent performances.
DET
Betting Trends
- The Tigers boast a 30–18 ATS record, demonstrating strong performance in covering the spread. Their home record is particularly impressive, with an 18–8 mark at Comerica Park, suggesting a significant home-field advantage.
MATCHUP TRENDS
- The Tigers’ 30–18 ATS record ranks among the best in MLB, highlighting their reliability for bettors. Conversely, the Giants’ 24–21 ATS record indicates a more unpredictable performance, especially on the road. The Tigers’ strong home record (18–8) further emphasizes their dominance at Comerica Park, making them a formidable opponent for visiting teams.
SF vs. DET
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: M. Chapman over 0.5 Total Bases.
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San Francisco vs Detroit Prediction & Odds:
Free MLB Betting Insights for 5/26/25
The Giants, averaging 4.6 runs per game, rely heavily on the production of Wilmer Flores, whose 10 home runs and 43 RBIs have kept them competitive in tight games. Though their team batting average sits at a modest .232, San Francisco has found ways to win with sharp pitching and a capable bullpen. Hayden Birdsong has been especially impressive on the mound, posting a 2–0 record with a sparkling 1.91 ERA and 29 strikeouts in 28.1 innings, and he represents the Giants’ best chance to slow down Detroit’s offense. San Francisco’s approach will likely focus on pitching to contact, keeping hitters off balance, and avoiding the big innings that Detroit thrives on. The Giants’ defense and bullpen execution will be critical, as Detroit has shown a knack for late-inning comebacks and clutch hitting. Strategically, this game sets up as a battle between Detroit’s ability to strike early and often with the bat and San Francisco’s effort to control the pace with their arms. Both teams understand the postseason implications of every game at this point in the season, and momentum, particularly for San Francisco on the road, can swing with a strong outing. Detroit will look to continue building its lead in the Central, while the Giants aim to stay close in the ultra-competitive West. If Birdsong can continue his dominance and the Giants can get on the board early, they’ll have a real chance to steal a win on the road. But if the Tigers’ bats get going, especially with Torkelson anchoring the heart of the lineup, Detroit could once again prove why they’ve been one of the best teams in baseball through the first two months of the season.
How can you not be romantic about baseball? pic.twitter.com/KaOVwiPDkq
— SFGiants (@SFGiants) May 25, 2025
San Francisco Giants MLB Preview
The San Francisco Giants enter their May 26, 2025 road matchup against the Detroit Tigers with a 31–22 record, positioned near the top of the competitive National League West and looking to gain ground on the division-leading Los Angeles Dodgers. On the surface, the Giants have been an above-average club with strengths centered around their pitching staff and a lineup that delivers in key moments despite middling overall batting statistics. Offensively, the Giants average 4.6 runs per game and have leaned heavily on veteran Wilmer Flores, who leads the team with 10 home runs and 43 RBIs, acting as the glue in an otherwise inconsistent lineup. Their collective .232 team batting average reflects a broader trend of offensive inconsistency, but they’ve found ways to scratch out wins thanks to timely hitting, situational base running, and discipline at the plate when it counts. On the mound, the Giants have received a major boost from Hayden Birdsong, who has emerged as one of the most reliable arms in the rotation with a 2–0 record, 1.91 ERA, and 29 strikeouts over 28.1 innings pitched. Birdsong’s command and ability to limit damage have allowed the Giants to stay in games even when the offense lags, and he’ll be instrumental in attempting to contain Detroit’s potent lineup. San Francisco’s bullpen has also been a strength, often tasked with protecting slim leads or keeping deficits manageable, and they’ve answered that call more often than not.
On the road, the Giants have been serviceable, holding a 14–13 record away from Oracle Park, showing they can compete in hostile environments but also highlighting the thin margin for error they typically face. Manager Gabe Kapler continues to push the right buttons tactically, frequently leveraging matchups and platoons to optimize performance even with limited power output across the roster. The challenge in this game will be slowing down a Tigers team that ranks among the league’s best at home and features a high-octane offense led by Spencer Torkelson. Kapler will likely look to mix in off-speed pitches and rely on his defense to stifle the Tigers’ rhythm, while also hoping for a few key hits early to put pressure on Keider Montero, Detroit’s young right-hander with a 5.28 ERA. Given Detroit’s strong record at Comerica Park, the Giants will need to play a clean game—limiting walks, avoiding defensive miscues, and finding a way to chip away offensively without relying on the long ball. For San Francisco, this matchup is less about overpowering the opponent and more about dictating tempo, controlling the strike zone, and executing in high-leverage moments. If they can keep the score tight and bring the bullpen into a close contest late, their road-tested resilience could make the difference. While the Tigers have the edge on paper, the Giants’ balance of experienced leadership and emerging pitching talent makes them a formidable opponent capable of pulling off a key road victory that could have meaningful implications in their divisional chase.
Credit: USA TODAY/IMAGN
Detroit Tigers MLB Preview
The Detroit Tigers host the San Francisco Giants on May 26, 2025, at Comerica Park riding a wave of confidence built on a strong 34–20 record and a commanding position atop the American League Central. Detroit has established itself as one of the league’s most consistent and balanced clubs this season, and its dominance at home—evidenced by an 18–8 record—has made Comerica Park a tough venue for visiting teams. The Tigers’ offensive engine is fueled by Spencer Torkelson, whose breakout campaign has included 13 home runs and 40 RBIs, placing him among the most productive hitters in the AL through the first two months of the season. His power threat in the middle of the lineup is complemented by a deep supporting cast capable of creating runs with both long balls and small ball tactics, as evidenced by their 5.24 runs per game average. Their lineup doesn’t rely solely on one star but rather gets contributions from top to bottom, making it difficult for opposing pitchers to navigate. The Tigers’ aggressive approach at the plate, coupled with good discipline and situational awareness, allows them to apply pressure throughout games and put pitchers in high-stress scenarios. On the mound, Detroit will turn to Keider Montero, a young arm still refining his game, who comes into the start with a 1–1 record and a 5.28 ERA.
While his numbers are not elite, Montero has flashed potential with strikeout ability and a fastball that plays well when he stays ahead in counts, and the Tigers will be looking for him to deliver five solid innings before turning things over to a capable bullpen. Detroit’s bullpen has quietly been a strength, frequently called upon to hold slim leads or stop rallies, and they’ve delivered with reliable late-game performances. Manager A.J. Hinch continues to push all the right buttons, blending analytics with a feel for momentum and matchups, and he’s guided the team with clarity and confidence. Defensively, the Tigers are fundamentally sound, rarely beating themselves with errors or mental lapses, and that consistency in the field has backed up their pitchers and reduced the pressure on Montero and company. Facing a Giants team that leans on strong pitching but has shown inconsistency at the plate, Detroit will likely look to strike early, setting the tone and forcing San Francisco into a reactive game plan. The Tigers have done a great job all season of punishing mistakes and capitalizing on free passes, and if they can continue that trend, they’ll put themselves in a favorable position to notch another win and extend their home success. With the crowd behind them and their confidence high, Detroit has every reason to believe they can handle business and continue building momentum toward a playoff push. As long as they stay focused and don’t overlook a capable San Francisco squad, the Tigers have all the tools to keep asserting their dominance in the American League and protect their home turf.
the @TarikSkubal experience 🙂↕️ pic.twitter.com/6VGN4yTnJT
— Detroit Tigers (@tigers) May 26, 2025
San Francisco vs. Detroit Prop Picks (AI)
San Francisco vs. Detroit Prediction (AI)
Remi, our AI sports wizard, has been pouring over exorbitant amounts of data from every angle between the Giants and Tigers and using recursive machine learning and impressive AI to crunch the data to a single cover probability.
The Algorithm has been most focused on the linear correlation of factor knucklehead sportsbettors tend to put on coaching factors between a Giants team going up against a possibly rested Tigers team. We’ve found the true game analytics appear to reflect a moderate lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.
Below is our current AI San Francisco vs Detroit picks, computer picks Giants vs Tigers, best bets, model edges, confidence ratings.
| DATE | GAME | LEAN | %WIN | UNITS | LEVEL | |
|---|---|---|---|---|---|---|
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Giants Betting Trends
The Giants have a 24–21 record against the spread (ATS) this season, indicating a moderate performance in covering the spread. They have been consistent, with a 4–6 record in their last ten games, reflecting some variability in recent performances.
Tigers Betting Trends
The Tigers boast a 30–18 ATS record, demonstrating strong performance in covering the spread. Their home record is particularly impressive, with an 18–8 mark at Comerica Park, suggesting a significant home-field advantage.
Giants vs. Tigers Matchup Trends
The Tigers’ 30–18 ATS record ranks among the best in MLB, highlighting their reliability for bettors. Conversely, the Giants’ 24–21 ATS record indicates a more unpredictable performance, especially on the road. The Tigers’ strong home record (18–8) further emphasizes their dominance at Comerica Park, making them a formidable opponent for visiting teams.
San Francisco vs. Detroit Game Info
What time does San Francisco vs Detroit start on May 26, 2025?
San Francisco vs Detroit starts on May 26, 2025 at 1:10 PM EST.
Where is San Francisco vs Detroit being played?
Venue: Comerica Park.
What are the opening odds for San Francisco vs Detroit?
Spread: Detroit +1.5
Moneyline: San Francisco -106, Detroit -112
Over/Under: 8
What are the records for San Francisco vs Detroit?
San Francisco: (31-22) | Detroit: (34-20)
What is the AI best bet for San Francisco vs Detroit?
Remi's searched hard and found the best prop for this matchup: M. Chapman over 0.5 Total Bases.. Prices move—always shop for the best number.
What are San Francisco vs Detroit trending bets?
The Tigers’ 30–18 ATS record ranks among the best in MLB, highlighting their reliability for bettors. Conversely, the Giants’ 24–21 ATS record indicates a more unpredictable performance, especially on the road. The Tigers’ strong home record (18–8) further emphasizes their dominance at Comerica Park, making them a formidable opponent for visiting teams.
What are San Francisco trending bets?
SF trend: The Giants have a 24–21 record against the spread (ATS) this season, indicating a moderate performance in covering the spread. They have been consistent, with a 4–6 record in their last ten games, reflecting some variability in recent performances.
What are Detroit trending bets?
DET trend: The Tigers boast a 30–18 ATS record, demonstrating strong performance in covering the spread. Their home record is particularly impressive, with an 18–8 mark at Comerica Park, suggesting a significant home-field advantage.
Where can I find AI Picks for San Francisco vs Detroit?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
San Francisco vs. Detroit Odds
AI algorithm Remi is pouring through loads of data on each player. In fact, anytime the San Francisco vs Detroit trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme altitude rarely follow normal, predictable patterns.
San Francisco vs Detroit Opening Odds
SF Moneyline:
-106 DET Moneyline: -112
SF Spread: -1.5
DET Spread: +1.5
Over/Under: 8
San Francisco vs Detroit Live Odds
| Games | PTS | ML | SPR | O/U |
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MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers San Francisco Giants vs. Detroit Tigers on May 26, 2025 at Comerica Park.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
| LEAN | %WIN | UNITS | RESULT | |
|---|---|---|---|---|
| LAD@TOR | TOR +1.5 | 56.7% | 2 | WIN |
| TOR@LAD | TOR +1.5 | 55.3% | 4 | WIN |
| TOR@SEA | OVER 7 | 54.9% | 3 | WIN |
| LAD@MIL | UNDER 7.5 | 56.6% | 6 | WIN |
| TOR@NYY | OVER 8 | 54.9% | 4 | WIN |
| TOR@NYY | CARLOS RODON OVER 1.5 TOTAL WALKS ALLOWED | 53.3% | 3 | WIN |
| NYY@TOR | OVER 7.5 | 54.8% | 2 | WIN |
| LAD@PHI | OVER 7 | 53.8% | 3 | WIN |
| SD@CHC | CHC -109 | 53.8% | 3 | WIN |
| SD@CHC | OVER 7.5 | 54.5% | 4 | LOSS |
| SD@CHC | CHC -111 | 54.8% | 4 | LOSS |
| CIN@LAD | SHOHEI OHTANI OVER 1.5 BASES | 53.5% | 3 | WIN |
| BOS@NYY | OVER 7 | 53.8% | 3 | LOSS |
| CIN@LAD | ELLY DE LA CRUZ OVER 0.5 BASES | 54.4% | 4 | LOSS |
| ARI@SD | SD -131 | 57.3% | 4 | WIN |
| DET@BOS | BOS -115 | 56.4% | 5 | WIN |
| NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
| HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
| NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
| STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
| KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
| MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
| MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
| WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
| LAA@COL | COL +108 | 50.5% | 3 | WIN |
| TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
| SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
| NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
| MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
| MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
| SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
| PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
| NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
| KC@PHI | PHI -130 | 58.3% | 4 | WIN |
| LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
| NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
| KC@CLE | KC -104 | 52.0% | 3 | WIN |
| CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
| WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
| LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
| TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
| SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
| SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
| MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
| NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
| TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
| TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
| ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
| PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
| ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
| SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |