Dodgers vs. Guardians
Prediction, Odds & Props
May 26 | MLB AI Picks
Updated: 2025-05-24T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
On May 26, 2025, the Los Angeles Dodgers (31–19) will face the Cleveland Guardians (27–22) at Progressive Field. The Dodgers aim to solidify their lead in the NL West, while the Guardians look to close the gap in the AL Central.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: May 26, 2025
Start Time: 6:10 PM EST
Venue: Progressive Field
Guardians Record: (29-23)
Dodgers Record: (32-21)
OPENING ODDS
LAD Moneyline: -176
CLE Moneyline: +147
LAD Spread: -1.5
CLE Spread: +1.5
Over/Under: 8
LAD
Betting Trends
- The Dodgers have gone 3–7 against the spread (ATS) in their last 10 games, indicating recent challenges in covering the run line.
CLE
Betting Trends
- The Guardians have a 4–6 ATS record over their past 10 games, reflecting inconsistencies in covering the spread at home.
MATCHUP TRENDS
- Both teams have struggled against the spread recently, with the Dodgers at 3–7 and the Guardians at 4–6 in their last 10 games, suggesting a potentially close matchup.
LAD vs. CLE
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: B. Naylor over 3.5 Fantasy Score.
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Los Angeles Dodgers vs Cleveland Prediction & Odds:
Free MLB Betting Insights for 5/26/25
Williams has shown poise and power in his pitches, but he’ll need to mix speeds and locate effectively to avoid giving up crooked numbers, especially in the early innings. The Guardians’ offensive hopes rest largely on José Ramírez, whose ability to hit for both power and average, while playing gold-glove defense, keeps Cleveland competitive even when the supporting cast is inconsistent. Over their last 10 games, the Guardians have averaged just 3.5 runs per game, a figure that won’t be enough unless they get exceptional pitching and timely hitting. Their bullpen has been mostly reliable, but if Williams is chased early, asking too much of the relievers could prove costly. With an over/under of 8 runs and the Dodgers favored at -176, oddsmakers are expecting a moderately high-scoring affair with Los Angeles likely to control the tempo. If the Dodgers establish an early lead behind Yamamoto, they are well-positioned to manage the game through their efficient defense and bullpen depth. But Cleveland has proven it can hang with anyone on their day, especially with Ramírez at the plate and Progressive Field providing a potential edge in a holiday atmosphere. Ultimately, this is a matchup of power vs. grit, depth vs. resilience, and should deliver a competitive game with playoff-like intensity as both teams aim to assert their place in the upper tier of their respective leagues.
SECOND PITCH OF THE GAME? HELLO, SHOHEI. pic.twitter.com/aNuSuofYD6
— Los Angeles Dodgers (@Dodgers) May 25, 2025
Los Angeles Dodgers Dodgers MLB Preview
The Los Angeles Dodgers enter their Memorial Day interleague matchup against the Cleveland Guardians with a 31–19 record and a firm hold atop the National League West, riding the strength of one of the most complete rosters in baseball. Despite a 3–7 mark against the spread in their last ten games, the Dodgers remain an elite team in every fundamental area—offense, defense, and pitching—and continue to strike fear into opponents with a relentless lineup and dominant starting rotation. Monday’s starter Yoshinobu Yamamoto has exceeded the high expectations placed on him during his first MLB campaign, entering the game with a sparkling 1.86 ERA and 0.914 WHIP. His ability to work both sides of the plate, command four pitches, and neutralize both righties and lefties has made him one of the most difficult pitchers to square up in the game, and he’ll look to quiet a Cleveland lineup that’s averaging just 3.5 runs per game over its last ten. On the offensive side, the Dodgers are a juggernaut, averaging 5.6 runs per game with Teoscar Hernández, Shohei Ohtani, Mookie Betts, and Freddie Freeman all capable of flipping a game with one swing. Hernández in particular has been productive with runners in scoring position, while Ohtani and Betts provide a combination of power, speed, and discipline that sets the tone at the top of the order. Even when one or two stars are quiet, Los Angeles can rely on its depth to generate runs through contact, patience, and timely base-running.
The Dodgers’ defense has also played a crucial role in their success, with elite infield play from Freeman and Betts and strong outfield coverage helping support the pitching staff and limit extended innings. While they’ve hit a recent rough patch against the spread, this is largely a reflection of inflated betting lines rather than a drop-off in performance—the team continues to win games, just not always by large margins. The bullpen, headlined by Daniel Hudson and Alex Vesia, has shown the ability to close out tight contests, and with Yamamoto expected to go deep, the relievers should be fresh and ready for late-inning matchups. Against Cleveland’s Gavin Williams, who has posted a respectable 3.94 ERA, the Dodgers will look to grind at-bats, elevate pitch counts, and force mistakes that their sluggers can capitalize on. Manager Dave Roberts has plenty of tools at his disposal and will aim to apply early pressure to prevent Cleveland from gaining any momentum at home. While no game is a guarantee, the Dodgers are built to handle pressure and have the upper hand in nearly every statistical and talent-based comparison in this matchup. With Yamamoto dealing and the offense continuing to fire, Los Angeles is well-positioned to secure a win, stay ahead in the division, and send a message to the rest of the league that they remain one of the most dangerous and complete teams in baseball in 2025.

Credit: USA TODAY/IMAGN
Cleveland Guardians MLB Preview
The Cleveland Guardians return to Progressive Field on May 26, 2025, to host the powerhouse Los Angeles Dodgers with a 27–22 record and their sights set firmly on remaining in the thick of the AL Central race. Though they have dropped six of their last ten and have a 4–6 record against the spread in that span, the Guardians have held their own through a combination of solid starting pitching, reliable bullpen arms, and the steady leadership of superstar José Ramírez. Ramírez continues to be the heartbeat of the club, contributing both offensively and defensively with consistent production, elite baserunning, and clutch plate appearances that have anchored a lineup still looking for more support. While Cleveland’s offense has averaged just 3.5 runs per game over their last ten outings, their ability to manufacture runs through small ball, aggressive base-running, and capitalizing on defensive miscues keeps them competitive, even when the long ball isn’t a major factor. Monday’s starter Gavin Williams will be tasked with slowing down a dangerous Dodgers lineup, and while his 4–2 record and 3.94 ERA don’t place him among the league’s elite, he has demonstrated poise and toughness in key situations. Williams features a high-velocity fastball and an evolving secondary pitch mix that has helped him pitch deep into games when he’s commanding the strike zone.
He’ll need to be at his best to contain an offense as deep and powerful as Los Angeles, which includes MVP-level talent at nearly every spot in the order. The Guardians’ bullpen has been one of their stronger assets, with a group of dependable arms that have effectively preserved leads and kept games within reach late, a trait that could be vital in a close, low-scoring affair. Defensively, Cleveland remains one of the more fundamentally sound teams in the American League, minimizing errors and executing double plays with precision—a crucial advantage when playing a team that thrives on creating chaos on the basepaths. The challenge for Cleveland in this game is not just stopping the Dodgers’ offense, but also finding ways to scratch across runs against Yoshinobu Yamamoto, who enters the game with a 1.86 ERA and dominant stuff that can shut down even the best hitters. Manager Stephen Vogt will likely emphasize aggressive situational hitting, trying to get runners on early and move them over while avoiding wasted opportunities, especially in the middle innings. If the Guardians can keep the game close and get to the Dodgers’ bullpen with a tie or small deficit, their ability to win close games could come into play. With a supportive holiday crowd behind them and the added motivation of going up against one of the league’s best teams, Cleveland has a chance to prove they belong among the contenders. A strong outing from Williams, timely hits from Ramírez, and a clean defensive performance would give the Guardians a legitimate shot to hand the Dodgers a rare loss and gain a critical win in their push to stay competitive in the American League playoff race.
Homeward bound.#GuardsBall pic.twitter.com/fFXvdOxWht
— Cleveland Guardians (@CleGuardians) May 25, 2025
Los Angeles Dodgers vs. Cleveland Prop Picks (AI)
Los Angeles Dodgers vs. Cleveland Prediction (AI)

Remi, our AI sports algorithm, has been pouring over exorbitant amounts of data from every past game between the Dodgers and Guardians and using recursive machine learning and industry leading AI to boil down the data to a single cover probability.
Interestingly enough, the data has been most watching on the unproportionally assigned factor human bettors regularly put on Cleveland’s strength factors between a Dodgers team going up against a possibly unhealthy Guardians team. We’ve found the true game analytics appear to reflect a strong lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.
Below is our current AI Los Angeles Dodgers vs Cleveland picks, computer picks Dodgers vs Guardians, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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Dodgers Betting Trends
The Dodgers have gone 3–7 against the spread (ATS) in their last 10 games, indicating recent challenges in covering the run line.
Guardians Betting Trends
The Guardians have a 4–6 ATS record over their past 10 games, reflecting inconsistencies in covering the spread at home.
Dodgers vs. Guardians Matchup Trends
Both teams have struggled against the spread recently, with the Dodgers at 3–7 and the Guardians at 4–6 in their last 10 games, suggesting a potentially close matchup.
Los Angeles Dodgers vs. Cleveland Game Info
What time does Los Angeles Dodgers vs Cleveland start on May 26, 2025?
Los Angeles Dodgers vs Cleveland starts on May 26, 2025 at 6:10 PM EST.
Where is Los Angeles Dodgers vs Cleveland being played?
Venue: Progressive Field.
What are the opening odds for Los Angeles Dodgers vs Cleveland?
Spread: Cleveland +1.5
Moneyline: Los Angeles Dodgers -176, Cleveland +147
Over/Under: 8
What are the records for Los Angeles Dodgers vs Cleveland?
Los Angeles Dodgers: (32-21) | Cleveland: (29-23)
What is the AI best bet for Los Angeles Dodgers vs Cleveland?
Remi's searched hard and found the best prop for this matchup: B. Naylor over 3.5 Fantasy Score.. Prices move—always shop for the best number.
What are Los Angeles Dodgers vs Cleveland trending bets?
Both teams have struggled against the spread recently, with the Dodgers at 3–7 and the Guardians at 4–6 in their last 10 games, suggesting a potentially close matchup.
What are Los Angeles Dodgers trending bets?
LAD trend: The Dodgers have gone 3–7 against the spread (ATS) in their last 10 games, indicating recent challenges in covering the run line.
What are Cleveland trending bets?
CLE trend: The Guardians have a 4–6 ATS record over their past 10 games, reflecting inconsistencies in covering the spread at home.
Where can I find AI Picks for Los Angeles Dodgers vs Cleveland?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
Los Angeles Dodgers vs. Cleveland Odds
AI algorithm Remi is pouring through tons of data points on each team. In fact, anytime the Los Angeles Dodgers vs Cleveland trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme travel distance rarely follow normal, predictable patterns.
Los Angeles Dodgers vs Cleveland Opening Odds
LAD Moneyline:
-176 CLE Moneyline: +147
LAD Spread: -1.5
CLE Spread: +1.5
Over/Under: 8
Los Angeles Dodgers vs Cleveland Live Odds
Games | PTS | ML | SPR | O/U | |
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San Francisco Giants
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Giants
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3
4
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U 7.5 (-326)
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O 3.5 (-138)
U 3.5 (+104)
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Detroit Tigers
Boston Red Sox
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Red Sox
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+440
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O 3.5 (-102)
U 3.5 (-130)
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Chicago White Sox
Washington Nationals
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White Sox
Nationals
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4
2
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-390
+280
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-1.5 (-158)
+1.5 (+118)
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O 9.5 (+128)
U 9.5 (-172)
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Minnesota Twins
Philadelphia Phillies
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Twins
Phillies
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1
0
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+136
-174
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+1.5 (-166)
-1.5 (+124)
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O 9.5 (+108)
U 9.5 (-144)
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Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
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–
–
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+116
-134
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+1.5 (-184)
-1.5 (+152)
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O 8 (-110)
U 8 (-110)
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Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
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–
–
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+144
-172
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+1.5 (-142)
-1.5 (+118)
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O 8 (-118)
U 8 (-104)
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Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
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–
–
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+128
-152
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+1.5 (-182)
-1.5 (+150)
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O 7.5 (+104)
U 7.5 (-128)
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Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
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–
–
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+130
-154
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+1.5 (-166)
-1.5 (+138)
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O 7.5 (-105)
U 7.5 (-115)
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Sep 27, 2025 9:39PM EDT
Houston Astros
Los Angeles Angels
9/27/25 9:39PM
Astros
Angels
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–
–
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-146
+124
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-1.5 (+112)
+1.5 (-134)
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O 9 (-108)
U 9 (-112)
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Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
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–
–
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+100
-118
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+1.5 (-215)
-1.5 (+176)
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O 7 (-118)
U 7 (-104)
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Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
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–
–
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+100
-118
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-1.5 (+150)
+1.5 (-182)
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O 10 (-114)
U 10 (-106)
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Sep 28, 2025 3:06PM EDT
Baltimore Orioles
New York Yankees
9/28/25 3:06PM
Orioles
Yankees
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–
–
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+144
-172
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+1.5 (-146)
-1.5 (+122)
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O 9 (-122)
U 9 (+100)
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Sep 28, 2025 3:06PM EDT
Colorado Rockies
San Francisco Giants
9/28/25 3:06PM
Rockies
Giants
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–
–
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+270
-335
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+1.5 (+112)
-1.5 (-134)
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O 7.5 (-110)
U 7.5 (-110)
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Sep 28, 2025 3:06PM EDT
Minnesota Twins
Philadelphia Phillies
9/28/25 3:06PM
Twins
Phillies
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–
–
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+180
-215
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+1.5 (-130)
-1.5 (+108)
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O 8 (-122)
U 8 (+100)
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MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Los Angeles Dodgers Dodgers vs. Cleveland Guardians on May 26, 2025 at Progressive Field.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
ARI@SD | SD -131 | 57.3% | 4 | WIN |
DET@BOS | BOS -115 | 56.4% | 5 | WIN |
NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
LAA@COL | COL +108 | 50.5% | 3 | WIN |
TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
KC@PHI | PHI -130 | 58.3% | 4 | WIN |
LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
KC@CLE | KC -104 | 52.0% | 3 | WIN |
CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |
PHI@NYM | OVER 8.5 | 55.6% | 4 | LOSS |
LAA@TEX | LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS | 54.1% | 4 | LOSS |
KC@CHW | KC -109 | 54.2% | 4 | WIN |
SD@SEA | DYLAN CEASE OVER 16.5 OUTS | 53.9% | 3 | LOSS |
SD@SEA | UNDER 8.5 | 54.4% | 4 | LOSS |
MIN@TOR | JOE RYAN UNDER 2.5 EARNED RUNS | 54.1% | 4 | LOSS |
SF@MIL | MIL +100 | 54.0% | 6 | LOSS |
TOR@MIA | MIA +1.5 | 62.0% | 6 | WIN |
CHC@LAA | OVER 9.5 | 54.9% | 4 | LOSS |
BOS@NYY | CARLOS RODON UNDER 4.5 HITS ALLOWED | 54.2% | 4 | WIN |
KC@DET | DET -115 | 56.1% | 5 | WIN |
CHC@LAA | LAA +1.5 | 57.6% | 5 | LOSS |