Dodgers vs. Guardians
Prediction, Odds & Props
May 26 | MLB AI Picks

Updated: 2025-05-24T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

On May 26, 2025, the Los Angeles Dodgers (31–19) will face the Cleveland Guardians (27–22) at Progressive Field. The Dodgers aim to solidify their lead in the NL West, while the Guardians look to close the gap in the AL Central.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: May 26, 2025

Start Time: 6:10 PM EST​

Venue: Progressive Field​

Guardians Record: (29-23)

Dodgers Record: (32-21)

OPENING ODDS

LAD Moneyline: -176

CLE Moneyline: +147

LAD Spread: -1.5

CLE Spread: +1.5

Over/Under: 8

LAD
Betting Trends

  • The Dodgers have gone 3–7 against the spread (ATS) in their last 10 games, indicating recent challenges in covering the run line.

CLE
Betting Trends

  • The Guardians have a 4–6 ATS record over their past 10 games, reflecting inconsistencies in covering the spread at home.

MATCHUP TRENDS

  • Both teams have struggled against the spread recently, with the Dodgers at 3–7 and the Guardians at 4–6 in their last 10 games, suggesting a potentially close matchup.

LAD vs. CLE
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: B. Naylor over 3.5 Fantasy Score.

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Los Angeles Dodgers vs Cleveland Prediction & Odds:
Free MLB Betting Insights for 5/26/25

The Memorial Day showdown on May 26, 2025, between the Los Angeles Dodgers and the Cleveland Guardians at Progressive Field is set to be one of the most intriguing interleague matchups of the day, featuring two teams with playoff aspirations and dynamic lineups. The Dodgers enter the game with a 31–19 record, leading the NL West behind a deep and powerful offense complemented by elite starting pitching, while the Guardians sit at 27–22, just behind the Minnesota Twins in the AL Central and looking to make a statement at home. Despite both clubs having struggled against the spread recently—Los Angeles at 3–7 and Cleveland at 4–6 over their last 10 games—their underlying numbers and rosters suggest a high-caliber battle ahead. Los Angeles will turn to ace Yoshinobu Yamamoto, who has been sensational in his first MLB season with a 1.86 ERA and a 0.914 WHIP, making him one of the most effective pitchers in the league. Yamamoto’s command and ability to induce soft contact have made him nearly unhittable, and with backup from an offense that includes Teoscar Hernández (among team leaders in RBIs), Shohei Ohtani, Mookie Betts, and Freddie Freeman, the Dodgers can shift the pressure quickly with one swing. Offensively, the Dodgers are averaging 5.6 runs per game, consistently overwhelming opponents with patience, power, and a relentless top-to-bottom lineup. For Cleveland, Gavin Williams will start the game with a 4–2 record and 3.94 ERA, a solid arm who will be asked to contain one of the most dangerous batting orders in baseball.

Williams has shown poise and power in his pitches, but he’ll need to mix speeds and locate effectively to avoid giving up crooked numbers, especially in the early innings. The Guardians’ offensive hopes rest largely on José Ramírez, whose ability to hit for both power and average, while playing gold-glove defense, keeps Cleveland competitive even when the supporting cast is inconsistent. Over their last 10 games, the Guardians have averaged just 3.5 runs per game, a figure that won’t be enough unless they get exceptional pitching and timely hitting. Their bullpen has been mostly reliable, but if Williams is chased early, asking too much of the relievers could prove costly. With an over/under of 8 runs and the Dodgers favored at -176, oddsmakers are expecting a moderately high-scoring affair with Los Angeles likely to control the tempo. If the Dodgers establish an early lead behind Yamamoto, they are well-positioned to manage the game through their efficient defense and bullpen depth. But Cleveland has proven it can hang with anyone on their day, especially with Ramírez at the plate and Progressive Field providing a potential edge in a holiday atmosphere. Ultimately, this is a matchup of power vs. grit, depth vs. resilience, and should deliver a competitive game with playoff-like intensity as both teams aim to assert their place in the upper tier of their respective leagues.

Los Angeles Dodgers Dodgers MLB Preview

The Los Angeles Dodgers enter their Memorial Day interleague matchup against the Cleveland Guardians with a 31–19 record and a firm hold atop the National League West, riding the strength of one of the most complete rosters in baseball. Despite a 3–7 mark against the spread in their last ten games, the Dodgers remain an elite team in every fundamental area—offense, defense, and pitching—and continue to strike fear into opponents with a relentless lineup and dominant starting rotation. Monday’s starter Yoshinobu Yamamoto has exceeded the high expectations placed on him during his first MLB campaign, entering the game with a sparkling 1.86 ERA and 0.914 WHIP. His ability to work both sides of the plate, command four pitches, and neutralize both righties and lefties has made him one of the most difficult pitchers to square up in the game, and he’ll look to quiet a Cleveland lineup that’s averaging just 3.5 runs per game over its last ten. On the offensive side, the Dodgers are a juggernaut, averaging 5.6 runs per game with Teoscar Hernández, Shohei Ohtani, Mookie Betts, and Freddie Freeman all capable of flipping a game with one swing. Hernández in particular has been productive with runners in scoring position, while Ohtani and Betts provide a combination of power, speed, and discipline that sets the tone at the top of the order. Even when one or two stars are quiet, Los Angeles can rely on its depth to generate runs through contact, patience, and timely base-running.

The Dodgers’ defense has also played a crucial role in their success, with elite infield play from Freeman and Betts and strong outfield coverage helping support the pitching staff and limit extended innings. While they’ve hit a recent rough patch against the spread, this is largely a reflection of inflated betting lines rather than a drop-off in performance—the team continues to win games, just not always by large margins. The bullpen, headlined by Daniel Hudson and Alex Vesia, has shown the ability to close out tight contests, and with Yamamoto expected to go deep, the relievers should be fresh and ready for late-inning matchups. Against Cleveland’s Gavin Williams, who has posted a respectable 3.94 ERA, the Dodgers will look to grind at-bats, elevate pitch counts, and force mistakes that their sluggers can capitalize on. Manager Dave Roberts has plenty of tools at his disposal and will aim to apply early pressure to prevent Cleveland from gaining any momentum at home. While no game is a guarantee, the Dodgers are built to handle pressure and have the upper hand in nearly every statistical and talent-based comparison in this matchup. With Yamamoto dealing and the offense continuing to fire, Los Angeles is well-positioned to secure a win, stay ahead in the division, and send a message to the rest of the league that they remain one of the most dangerous and complete teams in baseball in 2025.

On May 26, 2025, the Los Angeles Dodgers (31–19) will face the Cleveland Guardians (27–22) at Progressive Field. The Dodgers aim to solidify their lead in the NL West, while the Guardians look to close the gap in the AL Central. Los Angeles Dodgers vs Cleveland AI Prediction: Free MLB Betting Insights for May 26. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Cleveland Guardians MLB Preview

The Cleveland Guardians return to Progressive Field on May 26, 2025, to host the powerhouse Los Angeles Dodgers with a 27–22 record and their sights set firmly on remaining in the thick of the AL Central race. Though they have dropped six of their last ten and have a 4–6 record against the spread in that span, the Guardians have held their own through a combination of solid starting pitching, reliable bullpen arms, and the steady leadership of superstar José Ramírez. Ramírez continues to be the heartbeat of the club, contributing both offensively and defensively with consistent production, elite baserunning, and clutch plate appearances that have anchored a lineup still looking for more support. While Cleveland’s offense has averaged just 3.5 runs per game over their last ten outings, their ability to manufacture runs through small ball, aggressive base-running, and capitalizing on defensive miscues keeps them competitive, even when the long ball isn’t a major factor. Monday’s starter Gavin Williams will be tasked with slowing down a dangerous Dodgers lineup, and while his 4–2 record and 3.94 ERA don’t place him among the league’s elite, he has demonstrated poise and toughness in key situations. Williams features a high-velocity fastball and an evolving secondary pitch mix that has helped him pitch deep into games when he’s commanding the strike zone.

He’ll need to be at his best to contain an offense as deep and powerful as Los Angeles, which includes MVP-level talent at nearly every spot in the order. The Guardians’ bullpen has been one of their stronger assets, with a group of dependable arms that have effectively preserved leads and kept games within reach late, a trait that could be vital in a close, low-scoring affair. Defensively, Cleveland remains one of the more fundamentally sound teams in the American League, minimizing errors and executing double plays with precision—a crucial advantage when playing a team that thrives on creating chaos on the basepaths. The challenge for Cleveland in this game is not just stopping the Dodgers’ offense, but also finding ways to scratch across runs against Yoshinobu Yamamoto, who enters the game with a 1.86 ERA and dominant stuff that can shut down even the best hitters. Manager Stephen Vogt will likely emphasize aggressive situational hitting, trying to get runners on early and move them over while avoiding wasted opportunities, especially in the middle innings. If the Guardians can keep the game close and get to the Dodgers’ bullpen with a tie or small deficit, their ability to win close games could come into play. With a supportive holiday crowd behind them and the added motivation of going up against one of the league’s best teams, Cleveland has a chance to prove they belong among the contenders. A strong outing from Williams, timely hits from Ramírez, and a clean defensive performance would give the Guardians a legitimate shot to hand the Dodgers a rare loss and gain a critical win in their push to stay competitive in the American League playoff race.

Los Angeles Dodgers vs. Cleveland Prop Picks (AI)

AI algorithm Remi is pouring through mountains of stats on each line. In fact, anytime the Dodgers and Guardians play there’s always several intriguing trends to key in on. Not to mention games played at Progressive Field in May can often follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: B. Naylor over 3.5 Fantasy Score.

Los Angeles Dodgers vs. Cleveland Prediction (AI)

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Remi, our AI sports algorithm, has been pouring over exorbitant amounts of data from every past game between the Dodgers and Guardians and using recursive machine learning and industry leading AI to boil down the data to a single cover probability.

Interestingly enough, the data has been most watching on the unproportionally assigned factor human bettors regularly put on Cleveland’s strength factors between a Dodgers team going up against a possibly unhealthy Guardians team. We’ve found the true game analytics appear to reflect a strong lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI Los Angeles Dodgers vs Cleveland picks, computer picks Dodgers vs Guardians, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
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Dodgers Betting Trends

The Dodgers have gone 3–7 against the spread (ATS) in their last 10 games, indicating recent challenges in covering the run line.

Guardians Betting Trends

The Guardians have a 4–6 ATS record over their past 10 games, reflecting inconsistencies in covering the spread at home.

Dodgers vs. Guardians Matchup Trends

Both teams have struggled against the spread recently, with the Dodgers at 3–7 and the Guardians at 4–6 in their last 10 games, suggesting a potentially close matchup.

Los Angeles Dodgers vs. Cleveland Game Info

Los Angeles Dodgers vs Cleveland starts on May 26, 2025 at 6:10 PM EST.

Spread: Cleveland +1.5
Moneyline: Los Angeles Dodgers -176, Cleveland +147
Over/Under: 8

Los Angeles Dodgers: (32-21)  |  Cleveland: (29-23)

Remi's searched hard and found the best prop for this matchup: B. Naylor over 3.5 Fantasy Score.. Prices move—always shop for the best number.

Both teams have struggled against the spread recently, with the Dodgers at 3–7 and the Guardians at 4–6 in their last 10 games, suggesting a potentially close matchup.

LAD trend: The Dodgers have gone 3–7 against the spread (ATS) in their last 10 games, indicating recent challenges in covering the run line.

CLE trend: The Guardians have a 4–6 ATS record over their past 10 games, reflecting inconsistencies in covering the spread at home.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Los Angeles Dodgers vs. Cleveland Odds

AI algorithm Remi is pouring through tons of data points on each team. In fact, anytime the Los Angeles Dodgers vs Cleveland trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme travel distance rarely follow normal, predictable patterns.

Los Angeles Dodgers vs Cleveland Opening Odds

LAD Moneyline: -176
CLE Moneyline: +147
LAD Spread: -1.5
CLE Spread: +1.5
Over/Under: 8

Los Angeles Dodgers vs Cleveland Live Odds

Games PTS ML SPR O/U
In Progress
Colorado Rockies
San Francisco Giants
In Progress
Rockies
Giants
3
4
+680
-1400
-1.5 (+1000)
+1.5 (-3700)
O 7.5 (+234)
U 7.5 (-326)
In Progress
New York Mets
Miami Marlins
In Progress
Mets
Marlins
3
0
-5000
+1300
-2.5 (-300)
+2.5 (+210)
O 3.5 (-138)
U 3.5 (+104)
In Progress
Detroit Tigers
Boston Red Sox
In Progress
Tigers
Red Sox
2
1
-700
+440
-1.5 (+270)
+1.5 (-400)
O 3.5 (-102)
U 3.5 (-130)
In Progress
Chicago White Sox
Washington Nationals
In Progress
White Sox
Nationals
4
2
-390
+280
-1.5 (-158)
+1.5 (+118)
O 9.5 (+128)
U 9.5 (-172)
In Progress
Minnesota Twins
Philadelphia Phillies
In Progress
Twins
Phillies
1
0
+136
-174
+1.5 (-166)
-1.5 (+124)
O 9.5 (+108)
U 9.5 (-144)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+116
-134
+1.5 (-184)
-1.5 (+152)
O 8 (-110)
U 8 (-110)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+144
-172
+1.5 (-142)
-1.5 (+118)
O 8 (-118)
U 8 (-104)
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
+128
-152
+1.5 (-182)
-1.5 (+150)
O 7.5 (+104)
U 7.5 (-128)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+130
-154
+1.5 (-166)
-1.5 (+138)
O 7.5 (-105)
U 7.5 (-115)
Sep 27, 2025 9:39PM EDT
Houston Astros
Los Angeles Angels
9/27/25 9:39PM
Astros
Angels
-146
+124
-1.5 (+112)
+1.5 (-134)
O 9 (-108)
U 9 (-112)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+100
-118
+1.5 (-215)
-1.5 (+176)
O 7 (-118)
U 7 (-104)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
+100
-118
-1.5 (+150)
+1.5 (-182)
O 10 (-114)
U 10 (-106)
Sep 28, 2025 3:06PM EDT
Baltimore Orioles
New York Yankees
9/28/25 3:06PM
Orioles
Yankees
+144
-172
+1.5 (-146)
-1.5 (+122)
O 9 (-122)
U 9 (+100)
Sep 28, 2025 3:06PM EDT
Colorado Rockies
San Francisco Giants
9/28/25 3:06PM
Rockies
Giants
+270
-335
+1.5 (+112)
-1.5 (-134)
O 7.5 (-110)
U 7.5 (-110)
Sep 28, 2025 3:06PM EDT
Minnesota Twins
Philadelphia Phillies
9/28/25 3:06PM
Twins
Phillies
+180
-215
+1.5 (-130)
-1.5 (+108)
O 8 (-122)
U 8 (+100)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Los Angeles Dodgers Dodgers vs. Cleveland Guardians on May 26, 2025 at Progressive Field.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
ARI@SD SD -131 57.3% 4 WIN
DET@BOS BOS -115 56.4% 5 WIN
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS