Angels vs Athletics Prediction — AI Finds CAN'T MISS MLB Lines & Props (May 22)
Updated: 2025-05-20T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
On May 22, 2025, the Los Angeles Angels (18–25) will face the Oakland Athletics (22–27) at Sutter Health Park in Sacramento, concluding their four-game series. The Angels aim to secure a series split, while the Athletics look to capitalize on their home-field advantage to clinch the series.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: May 22, 2025
Start Time: 3:35 PM EST
Venue: Sutter Health Park
Athletics Record: (22-28)
Angels Record: (23-25)
OPENING ODDS
LAA Moneyline: +132
ATH Moneyline: -157
LAA Spread: +1.5
ATH Spread: -1.5
Over/Under: 10
LAA
Betting Trends
- The Angels have covered the spread in 4 of their last 5 games, showing a profit of 3.01 units.
ATH
Betting Trends
- The Athletics have a 4–6 record against the spread over their past 10 games.
MATCHUP TRENDS
- The total has gone OVER in 7 of the Athletics’ last 10 games, indicating a trend toward high-scoring contests.
LAA vs. ATH
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: T. Ward over 5.5 Fantasy Score.
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Los Angeles Angels vs Athletics Prediction & Odds:
Free MLB Betting Insights for 5/22/25
The rotation has struggled to pitch deep into games, and the bullpen has been inconsistent, forcing the offense to carry more than its fair share of the burden. Offensively, the A’s have averaged 4 runs per game behind the efforts of Brent Rooker and Zack Gelof, two of the team’s most consistent run producers. Rooker’s power bat and Gelof’s on-base ability have been pivotal in keeping Oakland competitive even when their pitching falters. The total has gone OVER in 7 of their last 10 games, a testament to both their ability to generate offense and their inability to suppress it on the other end. Playing in front of their home crowd at Sutter Health Park, the Athletics will attempt to use the hitter-friendly conditions to their advantage and pressure an Angels team still struggling to find consistency. This game is a crucial opportunity for both clubs: the Angels need the win to avoid another series defeat and gain traction in the division, while the Athletics can notch a valuable series win that might help them reset after a rocky two-week stretch. With both teams showcasing offensive upside and significant pitching vulnerabilities, the conditions are ripe for another high-scoring affair. The key will be which team’s starter can navigate the early innings and hand a lead to a bullpen capable of closing the door. Expect aggressive baserunning, quick hooks for starting pitchers, and a focus on run prevention in what could be a chaotic and entertaining series finale. With neither side boasting dominant arms, the bats will likely dictate the outcome, and whichever team capitalizes on mistakes will have the upper hand in this all-important divisional matchup.
ran it up 📈#RepTheHalo | #SoCalMcD pic.twitter.com/G3m0KPeGCJ
— Los Angeles Angels (@Angels) May 22, 2025
Los Angeles Angels Angels MLB Preview
The Los Angeles Angels head into the May 22 series finale against the Oakland Athletics looking to secure a much-needed split and continue building on what’s been an encouraging stretch of competitive play. Now 18–25, the Angels remain buried in the AL West standings, but they’ve covered the spread in four of their last five games, showing signs that the team is slowly beginning to stabilize after a rocky start to the season. Their offense has found life lately, thanks in large part to the emergence of Taylor Ward as the lineup’s most dependable threat. Ward leads the team with 12 home runs and 25 RBIs and has become the focal point of the Angels’ run production during a stretch where other stars have failed to produce consistently. His ability to handle both left- and right-handed pitching has made him a difficult matchup in the middle of the order, and his contributions will be key against an Oakland pitching staff that has surrendered a 7.41 ERA over its last 10 games. The Angels’ overall offensive average of 3.76 runs per game may not stand out, but recent games have been more productive, and they’re increasingly capitalizing on scoring opportunities. On the mound, Los Angeles will need its starter to give them quality innings—something the club has lacked consistently throughout the season.
Short starts have placed pressure on a bullpen that has actually performed better than expected in recent outings. The relievers have helped the team close out tight contests during this recent run, and the Angels’ improved ability to win close games could be a crucial edge in what’s expected to be a high-scoring series finale. Against an A’s team that has seen the total go OVER in seven of its last 10 games, the Angels’ hitters must remain aggressive early in counts and avoid the quiet innings that have derailed them in previous series. Los Angeles has been more disciplined at the plate of late, and if they can generate traffic and force Oakland into its bullpen early, they could be in a strong position to control the game. The Angels’ defense has also stepped up its game, with solid infield play helping to suppress some of the damage when contact is made, and catcher Logan O’Hoppe’s game-calling has improved the consistency of the pitching staff’s performance. Though the Angels are still far from being contenders, this game is an opportunity to continue the trend of forward progress and head into the next series with momentum. A win wouldn’t just secure a series split—it would mark another step toward relevance in a division where they cannot afford to fall further behind. For manager Ron Washington, the message will be simple: continue the offensive push, stay aggressive, and lean on the few reliable arms they’ve found to put away a vulnerable Oakland team that has shown it’s beatable when pressure is applied early and often.

Credit: USA TODAY/IMAGN
Athletics Athletics MLB Preview
The Oakland Athletics enter the May 22 series finale against the Los Angeles Angels with a 22–27 record and a prime opportunity to secure a series win at Sutter Health Park. After trading blows with the Angels over the past three games, the A’s will look to capitalize on their home-field advantage and rising offensive production to close out the set on a high note. While the pitching staff has been their Achilles’ heel throughout the season, Oakland has managed to keep games competitive thanks to a lineup that’s quietly averaging 4 runs per game and producing timely hits from young cornerstones like Brent Rooker and Zack Gelof. Rooker continues to be one of the team’s most dangerous power threats, showing a solid blend of patience and slugging, while Gelof has emerged as an on-base machine and dependable run scorer. The team’s recent scoring output has helped compensate for a rotation that has posted a brutal 7.41 ERA over its last 10 games, with starters struggling to pitch deep and often handing off multi-run deficits to a thin bullpen. Injuries have only made matters worse, with several key contributors unavailable and depth pieces forced into elevated roles they’ve not consistently filled. As a result, manager Mark Kotsay has had to get creative with bullpen usage, defensive alignments, and lineup combinations in an effort to spark momentum.
Despite those challenges, the A’s are still fighting, keeping many of their recent games within reach, even if the final results haven’t always gone their way. Their 4–6 ATS record in their last 10 reflects that trend—competitive but inconsistent. One major betting trend that has continued is the OVER hitting in seven of their last 10 games, especially at home, where the offensive conditions have benefited both their lineup and their opponents. That trend is expected to hold with the Angels bringing a hot bat in Taylor Ward and a lineup that has started to show signs of waking up. To win this series finale, the Athletics will need a rare strong start from their rotation—something they haven’t received with any regularity. The starter must avoid high pitch counts and walks early while limiting extra-base hits from the heart of the Angels’ lineup. Offensively, Oakland’s goal will be to jump on fastballs early in counts, extend innings with smart baserunning, and force the Angels’ bullpen into action before the middle innings. Defensively, sharper infield execution and outfield communication will be vital in containing Los Angeles’ aggressive approach. A win in this game wouldn’t just deliver a series victory—it would mark a needed boost in morale for a team that has flirted with .500 despite its flaws. With pressure growing to show improvement beyond moral victories, the A’s must lean on their offensive strengths and play mistake-free baseball in this finale if they hope to build momentum heading into a crucial stretch of the season.
450FT BOMB pic.twitter.com/T7foFomiJF
— Athletics (@Athletics) May 22, 2025
Los Angeles Angels vs. Athletics Prop Picks (AI)
Los Angeles Angels vs. Athletics Prediction (AI)

Remi, our AI sports genius, has been pouring over exorbitant amounts of data from every facet between the Angels and Athletics and using recursive machine learning and industry leading AI to crunch the data to a single cover probability.
The Algorithm has been most keyed in on the growing weight human bettors often put on player performance factors between a Angels team going up against a possibly unhealthy Athletics team. In reality, the true game analytics appear to reflect a moderate lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.
Below is our current AI Los Angeles Angels vs Athletics picks, computer picks Angels vs Athletics, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.
Angels Betting Trends
The Angels have covered the spread in 4 of their last 5 games, showing a profit of 3.01 units.
Athletics Betting Trends
The Athletics have a 4–6 record against the spread over their past 10 games.
Angels vs. Athletics Matchup Trends
The total has gone OVER in 7 of the Athletics’ last 10 games, indicating a trend toward high-scoring contests.
Los Angeles Angels vs. Athletics Game Info
What time does Los Angeles Angels vs Athletics start on May 22, 2025?
Los Angeles Angels vs Athletics starts on May 22, 2025 at 3:35 PM EST.
Where is Los Angeles Angels vs Athletics being played?
Venue: Sutter Health Park.
What are the opening odds for Los Angeles Angels vs Athletics?
Spread: Athletics -1.5
Moneyline: Los Angeles Angels +132, Athletics -157
Over/Under: 10
What are the records for Los Angeles Angels vs Athletics?
Los Angeles Angels: (23-25) | Athletics: (22-28)
What is the AI best bet for Los Angeles Angels vs Athletics?
Remi's searched hard and found the best prop for this matchup: T. Ward over 5.5 Fantasy Score.. Prices move—always shop for the best number.
What are Los Angeles Angels vs Athletics trending bets?
The total has gone OVER in 7 of the Athletics’ last 10 games, indicating a trend toward high-scoring contests.
What are Los Angeles Angels trending bets?
LAA trend: The Angels have covered the spread in 4 of their last 5 games, showing a profit of 3.01 units.
What are Athletics trending bets?
ATH trend: The Athletics have a 4–6 record against the spread over their past 10 games.
Where can I find AI Picks for Los Angeles Angels vs Athletics?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
Los Angeles Angels vs. Athletics Odds
AI algorithm Remi is pouring through mountains of stats on each team. In fact, anytime the Los Angeles Angels vs Athletics trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme hostile environments rarely follow normal, predictable betting trends.
Los Angeles Angels vs Athletics Opening Odds
LAA Moneyline:
+132 ATH Moneyline: -157
LAA Spread: +1.5
ATH Spread: -1.5
Over/Under: 10
Los Angeles Angels vs Athletics Live Odds
Games | PTS | ML | SPR | O/U | |
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Oct 19, 2025 8:04PM EDT
Seattle Mariners
Toronto Blue Jays
10/19/25 8:04PM
Mariners
Blue Jays
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–
–
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+108
-130
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+1.5 (-215)
-1.5 (+165)
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O 7.5 (-121)
U 7.5 (-106)
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MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Los Angeles Angels Angels vs. Athletics Athletics on May 22, 2025 at Sutter Health Park.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
TOR@SEA | OVER 7 | 54.9% | 3 | WIN |
LAD@MIL | UNDER 7.5 | 56.6% | 6 | WIN |
TOR@NYY | OVER 8 | 54.9% | 4 | WIN |
TOR@NYY | CARLOS RODON OVER 1.5 TOTAL WALKS ALLOWED | 53.3% | 3 | WIN |
NYY@TOR | OVER 7.5 | 54.8% | 2 | WIN |
LAD@PHI | OVER 7 | 53.8% | 3 | WIN |
SD@CHC | CHC -109 | 53.8% | 3 | WIN |
SD@CHC | OVER 7.5 | 54.5% | 4 | LOSS |
SD@CHC | CHC -111 | 54.8% | 4 | LOSS |
CIN@LAD | SHOHEI OHTANI OVER 1.5 BASES | 53.5% | 3 | WIN |
BOS@NYY | OVER 7 | 53.8% | 3 | LOSS |
CIN@LAD | ELLY DE LA CRUZ OVER 0.5 BASES | 54.4% | 4 | LOSS |
ARI@SD | SD -131 | 57.3% | 4 | WIN |
DET@BOS | BOS -115 | 56.4% | 5 | WIN |
NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
LAA@COL | COL +108 | 50.5% | 3 | WIN |
TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
KC@PHI | PHI -130 | 58.3% | 4 | WIN |
LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
KC@CLE | KC -104 | 52.0% | 3 | WIN |
CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |