Mariners vs. White Sox
Prediction, Odds & Props
May 20 | MLB AI Picks

Updated: 2025-05-18T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Seattle Mariners (24-18) visit the Chicago White Sox (14-33) on May 20, 2025, at Guaranteed Rate Field. Seattle aims to maintain their lead in the AL West, while Chicago continues to rebuild amidst a challenging season.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: May 20, 2025

Start Time: 7:40 PM EST​

Venue: Rate Field​

White Sox Record: (14-34)

Mariners Record: (27-19)

OPENING ODDS

SEA Moneyline: -177

CHW Moneyline: +149

SEA Spread: -1.5

CHW Spread: +1.5

Over/Under: 8

SEA
Betting Trends

  • The Mariners have covered the spread in 9 of their last 12 games, showcasing strong performance against the run line.

CHW
Betting Trends

  • The White Sox have struggled against the spread recently, with a 4-6 record in their last 10 games.

MATCHUP TRENDS

  • Seattle has been particularly effective on the road, covering the spread in 16 of their last 22 away games, indicating a strong trend when playing as visitors.

SEA vs. CHW
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: D. Moore over 0.5 Total Bases.

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Seattle vs Chicago White Sox Prediction & Odds:
Free MLB Betting Insights for 5/20/25

The May 20, 2025 matchup between the Seattle Mariners and the Chicago White Sox at Guaranteed Rate Field features two clubs at opposite ends of the competitive spectrum. The Mariners enter with a 24-18 record and sit atop the AL West, while the White Sox limp into the series at 14-33, buried in the AL Central and searching for direction amid a season already slipping away. Seattle arrives on the heels of a dominant sweep over the San Diego Padres, outscoring them 15-3 over three games and showcasing their ability to win with both pitching and timely hitting. Despite missing their top three starting pitchers, the Mariners have managed to stay afloat thanks to a deep, versatile roster and an offense that, while cooled somewhat in May, remains dangerous, particularly on the road where they boast a .332 wOBA and a 19.3% strikeout rate. Their bullpen has been under strain as the rotation fails to pitch deep into games, but the recent schedule offers relief in the form of the struggling White Sox, who have lost several games in blowout fashion and rank among the league’s worst in both offensive and pitching metrics. The Mariners have also been a strong bet for backers, covering the spread in 9 of their last 12 games and in 16 of their last 22 on the road. In contrast, the White Sox have been unable to generate consistent momentum, recently being swept by 18 runs at the hands of the Cubs, a series that emphasized both their lack of depth and inability to close out competitive games. While Chicago has seen flashes of potential from rookies like Chase Meidroth and Edgar Quero—both of whom offer long-term intrigue—the rest of the lineup remains woefully ineffective.

The Mariners will look to capitalize on this matchup by continuing to play aggressive but efficient baseball, getting early offense to relieve pressure on their bullpen, and taking advantage of the White Sox’s pitching vulnerabilities. Weather conditions could be a factor, with rain, wind, and cool temperatures expected, which may suppress power and put a premium on defense and execution. Still, Seattle holds clear advantages across the board in terms of roster depth, recent performance, and momentum. The Mariners know this is a prime opportunity to bank wins before facing tougher competition, while the White Sox continue to evaluate young talent in the midst of a rebuilding campaign. If the Mariners can get a respectable outing from their starter and maintain their plate discipline, they should be in prime position to extend their division lead and keep the White Sox mired in last place. For Chicago, the challenge lies not only in matching Seattle’s intensity but in proving they can compete against a playoff-caliber team—a tall task given their season-long struggles and lack of veteran anchors. As both teams take the field, it’s clear the pressure rests on the Mariners to avoid a letdown, while the White Sox simply hope to stay competitive in a series that, on paper, looks firmly tilted toward the visitors.

Seattle Mariners MLB Preview

The Seattle Mariners head into Guaranteed Rate Field on May 20, 2025, carrying a 24-18 record and a firm grip on first place in the AL West, seeking to extend their winning streak against a struggling Chicago White Sox team. Fresh off a dominant sweep of the San Diego Padres, in which they outscored their opponents 15-3 over three games, the Mariners have reestablished momentum despite enduring injuries to their top three starting pitchers. The absence of frontline arms has put pressure on the bullpen and mid-rotation starters, but Seattle’s depth and timely offense have helped them absorb that blow. Particularly impressive has been their road performance, with the team covering the spread in 16 of their last 22 away games and posting a .332 wOBA with a manageable 19.3% strikeout rate in those contests—evidence that their offensive production has traveled well. Key contributors like Julio Rodríguez and Cal Raleigh have been instrumental in anchoring the lineup, with Rodríguez finding his rhythm again at the plate and Raleigh offering both power and pitch-framing behind the plate. J.P. Crawford has been a consistent presence at the top of the lineup, giving the Mariners a solid on-base option who sets the tone for the offense. What makes Seattle particularly dangerous is their ability to win in multiple ways—whether through the long ball, small ball, or clean defensive play—and their aggressive baserunning has added pressure on opposing pitchers and defenses.

Even with a taxed bullpen, relievers like Andrés Muñoz and Gabe Speier have stepped up in high-leverage situations, helping Seattle close out tight games with poise. Manager Scott Servais has leaned on situational matchups and late-game strategy to navigate recent rotation shortages, and the team’s overall chemistry and discipline have helped them avoid extended losing streaks. Facing a White Sox team with one of the worst run differentials in baseball and a battered pitching staff, the Mariners are well-positioned to capitalize. The key for Seattle will be jumping on the White Sox early—putting runs on the board to avoid a bullpen battle and allowing their pitchers to work with a lead. Cold, wet weather in Chicago could play a factor, potentially limiting power output and making timely hitting and clean defense even more important. Still, this is a series the Mariners are expected to control, and anything less than a series win would be a disappointment for a club eyeing not just playoff contention but a potential deep October run. With a strong recent track record against the spread and a deep lineup capable of producing up and down the order, Seattle has every reason to feel confident as they continue their road trip against one of the league’s most vulnerable teams.

The Seattle Mariners (24-18) visit the Chicago White Sox (14-33) on May 20, 2025, at Guaranteed Rate Field. Seattle aims to maintain their lead in the AL West, while Chicago continues to rebuild amidst a challenging season. Seattle vs Chicago White Sox AI Prediction: Free MLB Betting Insights for May 20. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Chicago White Sox White Sox MLB Preview

The Chicago White Sox enter their May 20 matchup against the Seattle Mariners with a dismal 14-33 record and very few bright spots in what has already become a grueling 2025 campaign. Mired in last place in the AL Central and fresh off a demoralizing sweep at the hands of the Cubs in which they were outscored by 18 runs, the White Sox are facing a Mariners club trending in the opposite direction. Despite the losing record, there are a few individual storylines worth tracking, particularly the development of rookies like Chase Meidroth and Edgar Quero. Meidroth has shown advanced plate discipline and contact skills while batting leadoff, injecting a measure of excitement into a lineup that otherwise lacks consistent production. Quero, a promising young catcher, has flashed power potential and is learning quickly on the job, both defensively and at the plate. Still, beyond these young contributors, the offense remains largely ineffective. Former cornerstone Luis Robert Jr. leads the league in stolen bases but is batting under .200 and striking out in nearly one-third of his plate appearances, making his impact minimal overall. Andrew Vaughn has failed to build on his early-career promise, struggling with both power and plate discipline, while offseason additions have yet to make a meaningful difference. The team continues to suffer from a lack of offensive continuity, often failing to cash in with runners in scoring position and producing anemic run totals that make it difficult to stay competitive.

On the pitching side, things are equally grim. Davis Martin has overperformed relative to his peripherals but carries warning signs in the form of poor contact quality metrics that suggest regression is imminent. Bryse Wilson, while capable of eating innings, has struggled to suppress hard contact and often leaves games in the hands of a shaky bullpen. The lone standout has been Shane Smith, a Rule 5 pick who currently boasts a 2.05 ERA and has provided surprising value in an otherwise bleak rotation. The White Sox’s bullpen remains one of the most volatile in baseball, frequently unable to hold leads or keep deficits manageable. Defensively, the team has underperformed as well, compounding their pitching struggles with frequent lapses and unforced errors. Against a disciplined and opportunistic Seattle team, the White Sox will need a near-flawless effort to remain competitive. Cold, wet weather at Guaranteed Rate Field may suppress offense and level the playing field slightly, but unless the White Sox can string together quality at-bats and receive a standout start, they’re at risk of being quickly overwhelmed. Their recent 4-6 record against the spread mirrors their season-long inconsistency and lack of execution. With the focus now shifting more toward player development than wins, the White Sox’s challenge will be in maintaining morale and effort through a series where they enter as clear underdogs. A competitive showing against a first-place team would be a much-needed morale boost, but realistically, the odds are stacked high against a meaningful turnaround in the short term.

Seattle vs. Chicago White Sox Prop Picks (AI)

Remi is pouring through loads of data on each team. In fact, anytime the Mariners and White Sox play there’s always several intriguing trends to key in on. Not to mention games played at Rate Field in May can often follow normal, predictable patterns.
Remi's searched hard and found the best prop for this matchup: D. Moore over 0.5 Total Bases.

Seattle vs. Chicago White Sox Prediction (AI)

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Remi, our AI sports wizard, has been pouring over tons of data from every simulation between the Mariners and White Sox and using recursive machine learning and impressive AI to analyze the data to a single cover probability.

Oddly enough, we’ve seen the AI has been most focused on the unproportionally assigned emphasis human bettors tend to put on coaching factors between a Mariners team going up against a possibly unhealthy White Sox team. Trends look to say the true game analytics might reflect a moderate lean against one Vegas line specifically.

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Below is our current AI Seattle vs Chicago White Sox picks, computer picks Mariners vs White Sox, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
MLB 9/26 DET@BOS UNLOCK THIS PICK 5 EXECUTIVE Locked EXECUTIVE
MLB 9/26 BAL@NYY UNLOCK THIS PICK 4 INTEL Locked INTEL
MLB 9/26 ARI@SD UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
MLB 9/26 NYM@MIA UNLOCK THIS PICK 1 INTEL Locked INTEL
MLB 9/26 NYM@MIA GET FREE PICK NOW 1
MLB 9/26 COL@SF UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Mariners Betting Trends

The Mariners have covered the spread in 9 of their last 12 games, showcasing strong performance against the run line.

White Sox Betting Trends

The White Sox have struggled against the spread recently, with a 4-6 record in their last 10 games.

Mariners vs. White Sox Matchup Trends

Seattle has been particularly effective on the road, covering the spread in 16 of their last 22 away games, indicating a strong trend when playing as visitors.

Seattle vs. Chicago White Sox Game Info

Seattle vs Chicago White Sox starts on May 20, 2025 at 7:40 PM EST.

Spread: Chicago White Sox +1.5
Moneyline: Seattle -177, Chicago White Sox +149
Over/Under: 8

Seattle: (27-19)  |  Chicago White Sox: (14-34)

Remi's searched hard and found the best prop for this matchup: D. Moore over 0.5 Total Bases.. Prices move—always shop for the best number.

Seattle has been particularly effective on the road, covering the spread in 16 of their last 22 away games, indicating a strong trend when playing as visitors.

SEA trend: The Mariners have covered the spread in 9 of their last 12 games, showcasing strong performance against the run line.

CHW trend: The White Sox have struggled against the spread recently, with a 4-6 record in their last 10 games.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Seattle vs. Chicago White Sox Odds

Remi is pouring through tons of stats on each player. In fact, anytime the Seattle vs Chicago White Sox trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme altitude can often follow normal, predictable patterns.

Seattle vs Chicago White Sox Opening Odds

SEA Moneyline: -177
CHW Moneyline: +149
SEA Spread: -1.5
CHW Spread: +1.5
Over/Under: 8

Seattle vs Chicago White Sox Live Odds

Games PTS ML SPR O/U
Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
Orioles
Yankees
+190
-235
+1.5 (-110)
-1.5 (-110)
O 8.5 (-120)
U 8.5 (+100)
Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
 
-175
 
-1.5 (+115)
O 9.5 (-105)
U 9.5 (-115)
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
+130
-155
+1.5 (-155)
-1.5 (+130)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:06PM
White Sox
Nationals
+100
-120
-1.5 (+165)
+1.5 (-200)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
+185
-225
+1.5 (-110)
-1.5 (-110)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
-130
+110
-1.5 (+125)
+1.5 (-150)
O 8.5 (-105)
U 8.5 (-115)
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
+170
-205
+1.5 (-120)
-1.5 (+100)
O 8.5 (-115)
U 8.5 (-105)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+125
-150
+1.5 (-180)
-1.5 (+150)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+140
-170
+1.5 (-155)
-1.5 (+130)
O 8 (-110)
U 8 (-110)
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
+135
-165
+1.5 (-180)
-1.5 (+150)
O 7 (-120)
U 7 (+100)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+115
-140
+1.5 (-190)
-1.5 (+155)
O 7.5 (-120)
U 7.5 (+100)
Sep 27, 2025 9:39PM EDT
Houston Astros
Los Angeles Angels
9/27/25 9:39PM
Astros
Angels
-165
+135
-1.5 (+105)
+1.5 (-125)
O 9 (+100)
U 9 (-120)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+100
-120
-1.5 (+170)
+1.5 (-205)
O 7.5 (-110)
U 7.5 (-110)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
+100
-120
-1.5 (+150)
+1.5 (-180)
O 10 (-110)
U 10 (-110)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Seattle Mariners vs. Chicago White Sox White Sox on May 20, 2025 at Rate Field.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS
CIN@ARI KEBRYAN HAYES STRIKEOUTS UNDER 0.5 56.2% 6 WIN
LAD@SD SD +110 50.9% 6 WIN