Nationals vs. Orioles
Prediction, Odds & Props
May 17 | MLB AI Picks

Updated: 2025-05-15T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Washington Nationals and Baltimore Orioles continue their interleague series on Saturday, May 17, 2025, at Oriole Park at Camden Yards, with first pitch scheduled for 4:05 PM ET. Both teams are aiming to gain momentum in their respective divisions, with the Nationals looking to build on a recent win and the Orioles striving to snap a losing streak.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: May 17, 2025

Start Time: 4:05 PM EST​

Venue: Oriole Park at Camden Yards​

Orioles Record: (15-28)

Nationals Record: (19-27)

OPENING ODDS

WAS Moneyline: +134

BAL Moneyline: -159

WAS Spread: +1.5

BAL Spread: -1.5

Over/Under: 10

WAS
Betting Trends

  • The Nationals have a 17-26 record this season, with a 7-14 mark on the road, indicating struggles away from home.

BAL
Betting Trends

  • The Orioles hold a 15-27 record overall, with an 8-11 record at home, reflecting challenges in securing victories at Camden Yards.

MATCHUP TRENDS

  • Both teams have faced difficulties this season, with the Nationals and Orioles each striving to improve their standings. The Nationals’ recent road struggles and the Orioles’ home challenges add an intriguing dynamic to this matchup.

WAS vs. BAL
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: M. Handley under 4.5 Fantasy Score.

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Washington vs Baltimore Prediction & Odds:
Free MLB Betting Insights for 5/17/25

The interleague matchup between the Washington Nationals and Baltimore Orioles on Saturday, May 17, 2025, at Camden Yards presents a meaningful opportunity for both clubs to gain traction in otherwise difficult seasons. The Nationals come into the game at 17-26, buoyed by a narrow 4-3 win in the series opener, in which Nasim Nuñez delivered a clutch two-out infield single in the ninth to drive in the game-winning run. James Wood also contributed a solo home run and an RBI single, and Nathaniel Lowe went deep to show signs of life in a Washington offense that has struggled with consistency but flashes serious upside in key spots. On the season, the Nationals have been poor on the road, owning a 7-14 away record, yet they’ve demonstrated competitiveness and energy, particularly when their young core is clicking. Washington will need to lean on that group again Saturday, with CJ Abrams continuing to anchor the middle infield and contribute at the top of the lineup, and Keibert Ruiz bringing stability both behind the plate and in the batter’s box. Meanwhile, the Orioles sit at 15-27 and have lost four of their last five games, including the series opener against Washington. Injuries to key arms like Grayson Rodriguez and Tyler Wells have exposed Baltimore’s lack of depth on the mound, and the bullpen has struggled to hold leads or keep games close, making every inning more tense than it should be for the club’s position players.

Baltimore’s offense, which was expected to be a strength, has sputtered under the weight of inconsistent production and a lack of timely hitting, and their 8-11 home record reflects their broader struggles to find an identity in 2025. The Orioles are a team in flux, trying to rediscover the spark that fueled their breakout campaigns in prior years but hampered by injuries and the regression of several key contributors. Saturday’s game becomes a mental battle as much as a physical one—can the Orioles shake off the disappointment of repeated close losses and assert themselves at home, or will the Nationals ride their Friday win into a momentum-building series victory? Pitching matchups will be crucial, especially as Washington’s rotation looks to suppress the Orioles’ early-inning output and force their bullpen into pressure situations. For the Nationals, the game represents a chance to string together wins and begin crawling out of the NL East basement, while the Orioles desperately need a win to prevent further slipping in a competitive AL East where every series feels pivotal. Though both teams are far from playoff position, this game carries the weight of directional momentum—one team trying to punch upward with youthful enthusiasm, the other trying to recapture form before the season becomes unsalvageable. Expect a tight, grind-it-out ballgame with urgency on both sides and the possibility of another late-inning twist.

Washington Nationals MLB Preview

The Washington Nationals step into Saturday’s contest against the Baltimore Orioles riding the emotional lift of a narrow 4-3 victory in the series opener and aiming to build some rare momentum in what has been a challenging season. With a 17-26 record overall and just 7 wins in 21 road games, the Nationals have found success hard to come by outside of Nationals Park, but Friday’s win—secured by Nasim Nuñez’s two-out infield single in the ninth inning—offered a glimpse of their potential when the pieces come together. James Wood showcased his power and timing with a solo home run and an RBI single, while Nathaniel Lowe chipped in with a long ball of his own, giving Washington a much-needed offensive spark. The Nationals’ season has largely been defined by inconsistency, especially on the mound, where their rotation has struggled to provide deep outings and their bullpen has frequently been forced into early action. However, the core of young talent continues to grow in both confidence and performance, with CJ Abrams emerging as a key figure in the lineup thanks to his speed, defensive range, and clutch hitting, while Keibert Ruiz has remained a stabilizing force behind the plate and in the middle of the batting order.

The Nationals’ approach under manager Dave Martinez has leaned on development and patience, allowing their youthful roster to play through mistakes and take on responsibility in high-leverage situations—an approach that paid dividends in Friday’s come-from-behind win. Defensively, the Nationals have been sharp in stretches but remain vulnerable to lapses, and they’ll need a clean, focused effort to limit a Baltimore team that, despite its own struggles, still possesses dangerous bats capable of flipping a game in a single inning. Saturday’s game is an opportunity not just to win a series on the road—something Washington has rarely done this year—but to continue laying the foundation for a more competitive summer. The Nationals’ best path to victory will involve early offense to alleviate pressure on the pitching staff, sound defensive execution, and capitalizing on the Orioles’ recent bullpen instability. While the playoffs are not a realistic short-term goal, every win adds value to the developmental arc of this club, and games like these—against similarly struggling opponents—offer Washington a chance to refine its identity, build internal momentum, and provide fans with tangible signs of progress. With James Wood heating up, Lowe delivering power, and Abrams steering the offense at the top, the Nationals will look to strike early and lean on their youth-driven energy to finish strong and potentially notch a rare road series win.

The Washington Nationals and Baltimore Orioles continue their interleague series on Saturday, May 17, 2025, at Oriole Park at Camden Yards, with first pitch scheduled for 4:05 PM ET. Both teams are aiming to gain momentum in their respective divisions, with the Nationals looking to build on a recent win and the Orioles striving to snap a losing streak. Washington vs Baltimore AI Prediction: Free MLB Betting Insights for May 17. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Baltimore Orioles MLB Preview

The Baltimore Orioles head into Saturday’s game against the Washington Nationals in urgent need of a rebound, reeling from a frustrating 4-3 loss in the series opener that dropped their record to 15-27 and deepened a recent skid marked by inconsistency on both sides of the ball. That loss at Camden Yards was emblematic of their season—late-game struggles, missed scoring opportunities, and a bullpen unable to protect a tie in the ninth inning—problems that have plagued the Orioles all year. Injuries have significantly contributed to their underwhelming performance, most notably to key starting pitchers Grayson Rodriguez and Tyler Wells, whose absences have left a gap in the rotation and forced manager Brandon Hyde to rely heavily on younger arms and patchwork bullpen efforts. Baltimore’s 8-11 home record illustrates their inability to establish a fortress at Camden Yards, a troubling sign for a team that not long ago was regarded as one of the most promising up-and-coming clubs in the American League. Offensively, the Orioles have yet to find consistent rhythm despite having capable bats in their lineup. Adley Rutschman remains a leader both behind the plate and in the batter’s box, but he hasn’t received the consistent support he needs from the rest of the order. Gunnar Henderson and Ryan Mountcastle have flashed power, but streaky hitting and a lack of timely run production have hampered any sustained offensive momentum.

Saturday’s matchup offers the Orioles an opportunity to exploit a Washington pitching staff that has struggled on the road and is susceptible to early scoring—if Baltimore’s hitters can capitalize on mistakes and get ahead early, they could control the game rather than chase it. The pitching assignment for the day will be critical, as the staff will need to contain James Wood, who homered in the opener, and CJ Abrams, whose dynamic speed and bat make him a constant threat. Baltimore must also tighten its defense, which has been uncharacteristically sloppy in recent weeks, extending innings and placing undue strain on already fatigued pitchers. While their record doesn’t inspire much optimism at the moment, the Orioles still possess a foundation of young talent that has been tested and can respond with pride, particularly in front of their home fans. Hyde’s challenge will be getting this group to reset mentally, clean up execution, and rediscover the competitive edge that defined their ascension over the past two seasons. Saturday is more than just a mid-May game between two underperforming teams—it’s a potential turning point for Baltimore to regain belief and rhythm, beginning with situational hitting, sharper bullpen decision-making, and finding a way to win close games that have consistently slipped through their grasp. Against a Nationals team with similar struggles and a vulnerable road profile, this is the type of matchup the Orioles must capitalize on to avoid letting the season slip further away.

Washington vs. Baltimore Prop Picks (AI)

Remi is pouring through loads of data on each line. In fact, anytime the Nationals and Orioles play there’s always several intriguing trends to key in on. Not to mention games played at Oriole Park at Camden Yards in May almost always follow normal, predictable patterns.
Remi's searched hard and found the best prop for this matchup: M. Handley under 4.5 Fantasy Score.

Washington vs. Baltimore Prediction (AI)

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Remi, our AI sports wizard, has been pouring over tons of data from every simulation between the Nationals and Orioles and using recursive machine learning and cutting-edge AI to examine the data to a single cover probability.

Remi has been most focused on the linear correlation of emphasis knucklehead sportsbettors regularly put on coaching factors between a Nationals team going up against a possibly tired Orioles team. We’ve found the true game analytics appear to reflect a strong lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI Washington vs Baltimore picks, computer picks Nationals vs Orioles, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
MLB 9/26 DET@BOS UNLOCK THIS PICK 5 EXECUTIVE Locked EXECUTIVE
MLB 9/26 BAL@NYY UNLOCK THIS PICK 4 INTEL Locked INTEL
MLB 9/26 ARI@SD UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
MLB 9/26 NYM@MIA UNLOCK THIS PICK 1 INTEL Locked INTEL
MLB 9/26 NYM@MIA GET FREE PICK NOW 1
MLB 9/26 COL@SF UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Nationals Betting Trends

The Nationals have a 17-26 record this season, with a 7-14 mark on the road, indicating struggles away from home.

Orioles Betting Trends

The Orioles hold a 15-27 record overall, with an 8-11 record at home, reflecting challenges in securing victories at Camden Yards.

Nationals vs. Orioles Matchup Trends

Both teams have faced difficulties this season, with the Nationals and Orioles each striving to improve their standings. The Nationals’ recent road struggles and the Orioles’ home challenges add an intriguing dynamic to this matchup.

Washington vs. Baltimore Game Info

Washington vs Baltimore starts on May 17, 2025 at 4:05 PM EST.

Venue: Oriole Park at Camden Yards.

Spread: Baltimore -1.5
Moneyline: Washington +134, Baltimore -159
Over/Under: 10

Washington: (19-27)  |  Baltimore: (15-28)

Remi's searched hard and found the best prop for this matchup: M. Handley under 4.5 Fantasy Score.. Prices move—always shop for the best number.

Both teams have faced difficulties this season, with the Nationals and Orioles each striving to improve their standings. The Nationals’ recent road struggles and the Orioles’ home challenges add an intriguing dynamic to this matchup.

WAS trend: The Nationals have a 17-26 record this season, with a 7-14 mark on the road, indicating struggles away from home.

BAL trend: The Orioles hold a 15-27 record overall, with an 8-11 record at home, reflecting challenges in securing victories at Camden Yards.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Washington vs. Baltimore Odds

AI algorithm Remi is pouring through mountains of data points on each team. In fact, anytime the Washington vs Baltimore trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme hostile environments seemingly never follow normal, predictable betting trends.

Washington vs Baltimore Opening Odds

WAS Moneyline: +134
BAL Moneyline: -159
WAS Spread: +1.5
BAL Spread: -1.5
Over/Under: 10

Washington vs Baltimore Live Odds

Games PTS ML SPR O/U
Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
Orioles
Yankees
+190
-235
+1.5 (-110)
-1.5 (-110)
O 8.5 (-120)
U 8.5 (+100)
Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
 
-175
 
-1.5 (+115)
O 9.5 (-105)
U 9.5 (-115)
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
+130
-155
+1.5 (-155)
-1.5 (+130)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:06PM
White Sox
Nationals
+100
-120
-1.5 (+165)
+1.5 (-200)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
+185
-225
+1.5 (-110)
-1.5 (-110)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
-130
+110
-1.5 (+125)
+1.5 (-150)
O 8.5 (-105)
U 8.5 (-115)
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
+170
-205
+1.5 (-120)
-1.5 (+100)
O 8.5 (-115)
U 8.5 (-105)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+125
-150
+1.5 (-180)
-1.5 (+150)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+140
-170
+1.5 (-155)
-1.5 (+130)
O 8 (-110)
U 8 (-110)
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
+135
-165
+1.5 (-180)
-1.5 (+150)
O 7 (-120)
U 7 (+100)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+115
-140
+1.5 (-190)
-1.5 (+155)
O 7.5 (-120)
U 7.5 (+100)
Sep 27, 2025 9:39PM EDT
Houston Astros
Los Angeles Angels
9/27/25 9:39PM
Astros
Angels
-165
+135
-1.5 (+105)
+1.5 (-125)
O 9 (+100)
U 9 (-120)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+100
-120
-1.5 (+170)
+1.5 (-205)
O 7.5 (-110)
U 7.5 (-110)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
+100
-120
-1.5 (+150)
+1.5 (-180)
O 10 (-110)
U 10 (-110)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Washington Nationals vs. Baltimore Orioles on May 17, 2025 at Oriole Park at Camden Yards.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS
CIN@ARI KEBRYAN HAYES STRIKEOUTS UNDER 0.5 56.2% 6 WIN
LAD@SD SD +110 50.9% 6 WIN