Twins vs. Orioles
Prediction, Odds & Props
May 15 | MLB AI Picks

Updated: 2025-05-13T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

On May 15, 2025, the Minnesota Twins and Baltimore Orioles will clash at Oriole Park at Camden Yards in the final game of their series. Both teams are seeking momentum as they navigate challenging seasons in their respective divisions.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: May 15, 2025

Start Time: 12:35 PM EST​

Venue: Oriole Park at Camden Yards​

Orioles Record: (15-26)

Twins Record: (23-20)

OPENING ODDS

MIN Moneyline: +114

BAL Moneyline: -134

MIN Spread: +1.5

BAL Spread: -1.5

Over/Under: 9

MIN
Betting Trends

  • The Minnesota Twins have a 22-19 record against the spread (ATS) this season, covering 53.7% of the time.

BAL
Betting Trends

  • The Baltimore Orioles hold a 15-24 ATS record, covering only 38.5% of their games this season.

MATCHUP TRENDS

  • Despite their overall struggles, the Twins have been more reliable on the road, while the Orioles have faced challenges covering spreads at home, making this matchup intriguing for bettors.

MIN vs. BAL
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: H. Bader over 4.5 Fantasy Score.

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Minnesota vs Baltimore Prediction & Odds:
Free MLB Betting Insights for 5/15/25

The Minnesota Twins and Baltimore Orioles are set to wrap up their midweek series on May 15, 2025, at Oriole Park at Camden Yards, with both teams at very different junctures in their respective seasons—Minnesota looking to solidify its footing in the AL Central with a series win, while Baltimore continues to search for stability and consistency amid a frustrating stretch. The Twins enter the matchup with a 21–20 record and a stronger 22–19 mark against the spread, and they’ve quietly put together a respectable campaign built on a blend of timely hitting, solid outfield defense, and a rotation that has kept them competitive against even the top-tier lineups in the American League. Byron Buxton remains the driving force of the offense, hitting .264 with nine home runs and 26 RBIs while providing Gold Glove-caliber defense in center field, and he’s been supported by contributions from Trevor Larnach, who brings six home runs to the table, and the red-hot Harrison Bader, who enters the finale batting .298 and giving the Twins reliable contact in the lower half of the lineup. Minnesota’s pitching, while not overpowering, has been steady and efficient, with starters frequently working into the sixth inning and handing off to a bullpen that has limited late-game damage and kept the team in position to steal close games.

Baltimore, meanwhile, comes into the game with a 15–24 record and a 15–24 ATS mark, highlighting a lack of execution both on the scoreboard and at the betting window, particularly in close contests where bullpen reliability and defensive lapses have undermined any offensive momentum they’ve managed to generate. Despite these struggles, the Orioles have seen strong individual performances from Cedric Mullins, who leads the team with eight home runs and 25 RBIs, and Gunnar Henderson, who continues to impress with a .275 batting average and versatile infield defense. The problem for Baltimore has been piecing it all together—the rotation has been inconsistent, the bullpen has been prone to late-inning meltdowns, and the defense has committed untimely errors that have kept innings alive and led directly to runs. The Orioles will need a near-flawless outing in all phases to slow down Minnesota’s rhythm and salvage the finale, especially given their home woes and underwhelming record in day games and series-closing contests. This matchup offers a strong contrast in team identity: the Twins are playing fundamentally sound, low-mistake baseball that allows them to grind out wins, while the Orioles are still trying to find cohesion across their roster. If Minnesota’s starter can navigate through the top half of Baltimore’s order and the offense produces its usual blend of power and contact, the Twins are in excellent position to clinch a road series win and continue trending upward. For the Orioles, it’s a test of character and discipline—a chance to stop the bleeding and prove that despite a poor start, there’s still enough talent on the roster to compete with playoff-caliber teams.

Minnesota Twins MLB Preview

The Minnesota Twins head into the final game of their series against the Baltimore Orioles on May 15, 2025, with a 21–20 record and a clear opportunity to take control of their momentum as they fight to climb the AL Central standings. The Twins have been one of the more reliable teams on the road this season, especially against the spread, where their 22–19 ATS record reflects a team capable of playing fundamentally sound, low-mistake baseball in a variety of environments. Byron Buxton remains the centerpiece of their offensive attack, hitting .264 with nine home runs and 26 RBIs, providing a combination of speed, power, and elite center field defense that sets the tone for the club both in the batter’s box and in the field. Buxton’s ability to flip momentum with a solo shot or a highlight-reel catch continues to give the Twins an edge in tight games, and with Harrison Bader currently batting .298 and producing consistent contact from the lower half of the lineup, Minnesota has quietly built a roster that thrives on depth and timely execution. The power element is supplied by Trevor Larnach, who adds six home runs and has shown the ability to drive the ball to all fields, complementing Buxton and Bader with clutch hitting that has turned momentum in close series like this one.

Minnesota’s pitching staff has done its job well enough to support the offense, with starters regularly working through five or six innings and limiting big innings by getting ahead in counts and inducing weak contact, while the bullpen has stepped up to preserve leads with improved command and confidence. This reliable pitching presence has allowed manager Rocco Baldelli to manage games without burning out high-leverage arms and gives the team flexibility to win both low-scoring duels and late-inning battles. Defensively, the Twins have shown improvement across the board, making fewer errors and displaying better infield communication and outfield positioning—an underrated strength that has helped contain rallies and prevent extra-base hits in key situations. Minnesota’s ability to apply pressure without relying solely on the long ball makes them especially dangerous against teams with shaky bullpens or inconsistent defense, both areas where Baltimore has struggled all season. As the Twins aim to finish the series with a win, the key will be early scoring, clean defense, and maintaining the pitching rhythm that has carried them through much of May, especially against a Baltimore team that has often failed to close out games effectively. If the Twins continue playing the kind of disciplined, opportunistic baseball that has helped them stay above .500, they should be in strong position to leave Camden Yards with a road series win and renewed confidence heading into the next stretch of the season. With Buxton leading the charge and steady contributions from throughout the lineup and rotation, Minnesota appears to have the upper hand heading into Thursday’s finale.

On May 15, 2025, the Minnesota Twins and Baltimore Orioles will clash at Oriole Park at Camden Yards in the final game of their series. Both teams are seeking momentum as they navigate challenging seasons in their respective divisions. Minnesota vs Baltimore AI Prediction: Free MLB Betting Insights for May 15. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Baltimore Orioles MLB Preview

The Baltimore Orioles return to Oriole Park at Camden Yards on May 15, 2025, looking to snap out of a frustrating stretch and avoid a home series loss to the Minnesota Twins, entering the finale with a 15–24 record and a growing sense of urgency as they continue to struggle with consistency in all phases of the game. Offensively, the Orioles haven’t lacked firepower at the top, with Cedric Mullins leading the team with eight home runs and 25 RBIs, while Gunnar Henderson continues to hit for average at .275 and provide spark with his defense and baserunning, but those individual efforts have not been enough to carry a lineup that too often stalls with runners in scoring position or fades in the later innings. The core issue has been a lack of cohesion and depth across the batting order, and while they’ve had moments of energy and potential, Baltimore has struggled to turn that into sustained offense, particularly against teams with efficient starting rotations like the Twins. On the pitching side, the Orioles’ staff has failed to consistently give the team quality starts, forcing heavy bullpen usage early in games and resulting in late-game breakdowns that have allowed opponents to pull away—one of the reasons the Orioles have a 15–24 record both overall and against the spread, one of the lowest marks in the league. Their team ERA has ballooned due to walks, defensive lapses, and the inability to strand runners, and while individual pitchers have had flashes of command and velocity, the collective unit has lacked the execution to hold off potent lineups when the pressure ramps up.

Defensively, Baltimore has also faltered, committing costly errors and failing to turn key double plays in high-leverage situations, all of which have contributed to their inability to close out tight games at home. Manager Brandon Hyde has continued to preach patience and improvement, but with the team underperforming expectations, especially at Camden Yards, the pressure to turn things around is mounting fast. The Orioles’ best chance to win Thursday’s finale lies in early offense—jumping on the Twins’ starter before he settles in, giving the bullpen some breathing room, and playing mistake-free baseball for nine innings. With Mullins and Henderson producing at a high level, Baltimore still has the talent to compete and push opposing pitching staffs, but the rest of the roster needs to step up to support them if they hope to reverse the trend. A strong, disciplined start on the mound and crisp infield play will be key against a Minnesota team that has played efficiently and capitalized on mistakes all series. If the Orioles can take care of the fundamentals, limit free passes, and get timely hits from the bottom half of the order, they could finally notch a statement win at home and build a bit of momentum moving into the next series. Otherwise, the narrative of missed opportunities and underperformance may continue to define their 2025 campaign.

Minnesota vs. Baltimore Prop Picks (AI)

Remi is pouring through mountains of datapoints on each team. In fact, anytime the Twins and Orioles play there’s always several intriguing trends to key in on. Not to mention games played at Oriole Park at Camden Yards in May rarely follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: H. Bader over 4.5 Fantasy Score.

Minnesota vs. Baltimore Prediction (AI)

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Remi, our AI sports genius, has been pouring over exorbitant amounts of data from every past game between the Twins and Orioles and using recursive machine learning and kick-ass AI to crunch the data to a single cover probability.

Interestingly enough, the data has been most keyed in on the growing weight knucklehead sportsbettors often put on player performance factors between a Twins team going up against a possibly strong Orioles team. It appears the true game analytics appear to reflect a strong lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI Minnesota vs Baltimore picks, computer picks Twins vs Orioles, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
MLB 9/26 DET@BOS UNLOCK THIS PICK 5 EXECUTIVE Locked EXECUTIVE
MLB 9/26 BAL@NYY UNLOCK THIS PICK 4 INTEL Locked INTEL
MLB 9/26 ARI@SD UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
MLB 9/26 NYM@MIA UNLOCK THIS PICK 1 INTEL Locked INTEL
MLB 9/26 NYM@MIA GET FREE PICK NOW 1
MLB 9/26 COL@SF UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Twins Betting Trends

The Minnesota Twins have a 22-19 record against the spread (ATS) this season, covering 53.7% of the time.

Orioles Betting Trends

The Baltimore Orioles hold a 15-24 ATS record, covering only 38.5% of their games this season.

Twins vs. Orioles Matchup Trends

Despite their overall struggles, the Twins have been more reliable on the road, while the Orioles have faced challenges covering spreads at home, making this matchup intriguing for bettors.

Minnesota vs. Baltimore Game Info

Minnesota vs Baltimore starts on May 15, 2025 at 12:35 PM EST.

Venue: Oriole Park at Camden Yards.

Spread: Baltimore -1.5
Moneyline: Minnesota +114, Baltimore -134
Over/Under: 9

Minnesota: (23-20)  |  Baltimore: (15-26)

Remi's searched hard and found the best prop for this matchup: H. Bader over 4.5 Fantasy Score.. Prices move—always shop for the best number.

Despite their overall struggles, the Twins have been more reliable on the road, while the Orioles have faced challenges covering spreads at home, making this matchup intriguing for bettors.

MIN trend: The Minnesota Twins have a 22-19 record against the spread (ATS) this season, covering 53.7% of the time.

BAL trend: The Baltimore Orioles hold a 15-24 ATS record, covering only 38.5% of their games this season.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Minnesota vs. Baltimore Odds

AI algorithm Remi is pouring through mountains of stats on each team. In fact, anytime the Minnesota vs Baltimore trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme travel distance seemingly never follow normal, predictable patterns.

Minnesota vs Baltimore Opening Odds

MIN Moneyline: +114
BAL Moneyline: -134
MIN Spread: +1.5
BAL Spread: -1.5
Over/Under: 9

Minnesota vs Baltimore Live Odds

Games PTS ML SPR O/U
Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
Orioles
Yankees
+190
-235
+1.5 (-110)
-1.5 (-110)
O 8.5 (-120)
U 8.5 (+100)
Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
 
-175
 
-1.5 (+115)
O 9.5 (-105)
U 9.5 (-115)
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
+130
-155
+1.5 (-155)
-1.5 (+130)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:06PM
White Sox
Nationals
+100
-120
-1.5 (+165)
+1.5 (-200)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
+185
-225
+1.5 (-110)
-1.5 (-110)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
-130
+110
-1.5 (+125)
+1.5 (-150)
O 8.5 (-105)
U 8.5 (-115)
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
+170
-205
+1.5 (-120)
-1.5 (+100)
O 8.5 (-115)
U 8.5 (-105)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+125
-150
+1.5 (-180)
-1.5 (+150)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+140
-170
+1.5 (-155)
-1.5 (+130)
O 8 (-110)
U 8 (-110)
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
+135
-165
+1.5 (-180)
-1.5 (+150)
O 7 (-120)
U 7 (+100)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+115
-140
+1.5 (-190)
-1.5 (+155)
O 7.5 (-120)
U 7.5 (+100)
Sep 27, 2025 9:39PM EDT
Houston Astros
Los Angeles Angels
9/27/25 9:39PM
Astros
Angels
-165
+135
-1.5 (+105)
+1.5 (-125)
O 9 (+100)
U 9 (-120)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+100
-120
-1.5 (+170)
+1.5 (-205)
O 7.5 (-110)
U 7.5 (-110)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
+100
-120
-1.5 (+150)
+1.5 (-180)
O 10 (-110)
U 10 (-110)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Minnesota Twins vs. Baltimore Orioles on May 15, 2025 at Oriole Park at Camden Yards.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS
CIN@ARI KEBRYAN HAYES STRIKEOUTS UNDER 0.5 56.2% 6 WIN
LAD@SD SD +110 50.9% 6 WIN