Angels vs Padres Prediction — AI Finds CAN'T MISS MLB Lines & Props (May 14)

Updated: 2025-05-12T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

On May 14, 2025, the Los Angeles Angels (17–24) will face the San Diego Padres (26–15) at Petco Park in San Diego. The Padres aim to capitalize on their home-field advantage, while the Angels seek to rebound from recent losses.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: May 14, 2025

Start Time: 9:40 PM EST​

Venue: Petco Park​

Padres Record: (26-15)

Angels Record: (17-24)

OPENING ODDS

LAA Moneyline: +156

SD Moneyline: -188

LAA Spread: +1.5

SD Spread: -1.5

Over/Under: 9

LAA
Betting Trends

  • The Angels have a 4–6 record against the spread (ATS) over their last 10 games, indicating some inconsistency in covering spreads recently.

SD
Betting Trends

  • The Padres have an 8–2 ATS record over their past 10 games, reflecting strong performance in covering spreads recently.

MATCHUP TRENDS

  • The Padres have been favorites in 20 games this season and won 15 (75%) of those contests.

LAA vs. SD
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: R. Vasquez under 21.5 Fantasy Score.

LIVE MLB ODDS

MLB ODDS COMPARISON

WANT MORE AI PICKS?

VAULT
VS. SPREAD
341-258
VAULT
NET UNITS
(INCL VIG)
+373.5
VAULT
NET PROFIT
(INCL VIG)
$100/UNIT
$37,349
EXECUTIVE
VS. SPREAD
1598-1366
EXECUTIVE
NET UNITS
(INCL VIG)
+376.6
EXECUTIVE
NET PROFIT
(INCL VIG)
$100/UNIT
$37,657

AI SPORTS PICK PRODUCTS

Create a Free Account

‘Create an Account’ to Get Remi’s Picks Today.

Remi Finds New Picks

Remi calculates the probability a team will cover the line.

Remi Works 24/7

Remi uses this probability to assign units to each pick.

Get Remi's AI Picks

Get Remi’s Top AI Sports Picks sent direct to your inbox.

Los Angeles Angels vs San Diego Prediction & Odds:
Free MLB Betting Insights for 5/14/25

The Los Angeles Angels and San Diego Padres will close out their three-game interleague series on May 14, 2025, at Petco Park, with the Padres entering the finale as clear favorites thanks to their impressive home form, recent dominance against the spread, and an offense that has consistently overwhelmed opponents with depth and firepower. San Diego sits at 26–15 and boasts a 14–7 home record, having gone 8–2 against the spread in their last 10 games, while also winning 75% of their contests when listed as the favorite, showing they’ve excelled when expected to win and rarely play down to lesser opponents. They’ll hand the ball to Randy Vasquez, who brings a 2–1 record and a 3.45 ERA into the matchup and has given the Padres valuable innings with his ability to mix pitches and induce soft contact, especially in pitcher-friendly Petco Park where big innings are hard to come by when the starter is on his game. Offensively, the Padres are averaging 6.7 runs per game over their last 10 outings and are led by the electrifying Fernando Tatis Jr., who has nine home runs and 23 RBIs this season, acting as both a table-setter and power threat alongside a supporting cast that includes Luis Campusano and Jurickson Profar, who have each provided timely hits and consistent production to lengthen the lineup. On the other side, the Angels limp into this series finale at 17–24, with a 7–13 road record and a team that has struggled to find consistency in any phase, whether it’s sustaining offense, holding leads with the bullpen, or generating clean defensive innings that can help protect narrow advantages.

They’ll start Jose Soriano, who has shown flashes of potential but holds a 2–4 record and 4.00 ERA, and will be under immense pressure to deliver a shutdown performance against a Padres lineup that has punished mistakes and excelled at home in both night and day games. Soriano’s margin for error is thin given that the Angels’ lineup has lacked consistent power and run support, with rookie first baseman Nolan Schanuel (.258 average, six doubles, a triple, and two home runs) serving as a rare bright spot in an offense that often stalls when asked to come from behind. Los Angeles has gone 4–6 ATS in its last 10 games and has struggled to keep games close on the road, further complicating their ability to cover or upset stronger teams, especially those with the Padres’ firepower. The Angels will need timely hits, mistake-free defense, and a strong bullpen outing to stay competitive, but the odds tilt heavily in San Diego’s favor, especially if Vasquez delivers early and the Padres’ offense keeps pace with recent trends. This series finale represents another opportunity for the Padres to reinforce their growing case as a legitimate contender in the National League, while the Angels are left to find glimpses of progress and development amid a season that is quickly shifting toward evaluation mode unless they can pull off a much-needed turnaround starting with a surprise win in San Diego.

Los Angeles Angels Angels MLB Preview

The Los Angeles Angels enter their May 14, 2025 matchup against the San Diego Padres with a 17–24 record and plenty of questions surrounding their ability to compete on the road, where they’ve struggled to a 7–13 mark and have dropped several winnable games due to inconsistent pitching, defensive lapses, and an offense that has lacked timely production in high-leverage moments. This series finale at Petco Park offers an uphill challenge for a team still trying to find its identity in the post-Ohtani era, and they’ll turn to Jose Soriano on the mound, a right-hander who has shown potential but carries a 2–4 record and a 4.00 ERA into this start, needing to be sharp against a Padres offense that has averaged 6.7 runs per game over its last 10 and thrives in front of its home crowd. Soriano’s ability to command the zone and avoid big innings will be crucial, especially with the Angels’ bullpen having been one of the more erratic units in the American League, often unable to hold leads or keep games within reach when starters exit early. Offensively, the Angels are led by rookie Nolan Schanuel, who has been a rare bright spot this season with a .258 average, six doubles, a triple, and a pair of home runs, showing a solid approach at the plate and the kind of on-base ability that the lineup desperately needs from the top half, but beyond Schanuel, the Angels have failed to establish any real rhythm offensively, with streaky run production and little margin for error when they fall behind early.

The absence of consistent power threats and a lack of depth in the lineup have allowed opposing pitchers to challenge Angels hitters more aggressively, leading to higher strikeout rates and limited opportunities to manufacture runs, particularly on the road where the pressure to score quickly has led to poor plate discipline and missed chances. Defensively, Los Angeles has not been sharp enough to compensate for its offensive limitations, with fundamental mistakes and missed double-play chances extending innings and putting unnecessary strain on the pitching staff, and unless they can clean things up behind Soriano and give him early run support, it’s difficult to envision a scenario where the Angels can contain a surging Padres team. While their 4–6 record against the spread in the last 10 games suggests they’ve been somewhat competitive, they’ve routinely fallen short in close games due to bullpen meltdowns, defensive miscues, and missed opportunities at the plate. For the Angels to steal a win in this series finale, they’ll need a nearly perfect start from Soriano, a timely offensive breakout led by Schanuel or a surprise contributor, and airtight defense that minimizes extra outs and limits the damage that the Padres can inflict in big innings—an unlikely but not impossible formula. If Los Angeles can put those pieces together and play a clean, aggressive game, they have a shot to salvage the series, but if recent trends continue, they’re likely headed for another frustrating road loss in what’s shaping up to be a long season.

On May 14, 2025, the Los Angeles Angels (17–24) will face the San Diego Padres (26–15) at Petco Park in San Diego. The Padres aim to capitalize on their home-field advantage, while the Angels seek to rebound from recent losses. Los Angeles Angels vs San Diego AI Prediction: Free MLB Betting Insights for May 14. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

San Diego Padres MLB Preview

The San Diego Padres return to Petco Park for the final game of their three-game series against the Los Angeles Angels on May 14, 2025, with a 26–15 record and riding a wave of momentum built on excellent home-field play, a red-hot offense, and one of the best recent stretches against the spread in Major League Baseball, having gone 8–2 ATS over their last 10 games. San Diego holds a 14–7 home record and has done a tremendous job capitalizing on weaker opponents, particularly when their bats are locked in and their pitching staff provides early stability, both of which have been evident throughout this series. Randy Vasquez gets the start for the Padres, entering the game with a 2–1 record and a 3.45 ERA, and he’s quickly become a reliable presence at the back of the rotation by mixing pitches well, working deep into counts, and giving the Padres a chance to control games from the outset—especially important in a series where their opponent has struggled to score early. Offensively, the Padres have averaged 6.7 runs per game over their last 10, led by the explosive Fernando Tatis Jr., who has slugged nine home runs and driven in 23 RBIs this season while reasserting himself as the most dynamic player in the lineup and a spark for San Diego’s aggressive offensive approach.

Tatis’s resurgence has opened things up for the rest of the lineup, with Jurickson Profar, Luis Campusano, and Jake Cronenworth providing additional pop and on-base production that allows the Padres to pressure opposing pitchers from the first pitch to the last out. Petco Park, while traditionally a pitcher’s park, has become a place where the Padres know how to manufacture runs and use their athleticism to beat teams both with the long ball and aggressive base running, and their defense has been equally sharp, turning double plays and making highlight-reel grabs that protect leads and energize the home crowd. The bullpen has also held up well, with key arms like Robert Suarez and Yuki Matsui closing the door late and giving manager Mike Shildt confidence in his ability to manage tight games without overextending starters like Vasquez. Against an Angels team that has gone just 7–13 on the road and has failed to provide consistent run support or late-inning resistance, the Padres are well-positioned to apply early pressure and ride their offensive firepower and deep pitching staff to another series-clinching win. With the way the team is playing, particularly at home, this game represents another opportunity to assert their control in the National League and continue to close the gap on the division lead while building confidence, cohesion, and consistency in all phases of the game. If the Padres continue to play to their strengths—jumping ahead early, staying aggressive on the bases, and protecting leads with sound defense and bullpen execution—they should have no problem finishing off a sweep and extending one of the hottest stretches of their season.

Los Angeles Angels vs. San Diego Prop Picks (AI)

AI algorithm Remi is pouring through mountains of stats on each line. In fact, anytime the Angels and Padres play there’s always several intriguing angles to key in on. Not to mention games played at Petco Park in May rarely follow normal, predictable patterns.
Remi's searched hard and found the best prop for this matchup: R. Vasquez under 21.5 Fantasy Score.

Los Angeles Angels vs. San Diego Prediction (AI)

Remi Robot Icon

Remi, our AI sports algorithm, has been pouring over tons of data from every simulation between the Angels and Padres and using recursive machine learning and industry leading AI to analyze the data to a single cover probability.

The Algorithm has been most fixated on the growing factor knucklehead sportsbettors often put on coaching factors between a Angels team going up against a possibly rested Padres team. We’ve found the true game analytics appear to reflect a slight lean against one Vegas line specifically.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI Los Angeles Angels vs San Diego picks, computer picks Angels vs Padres, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
ACTIVE PICKS LOCKED - SEE NOW

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Angels Betting Trends

The Angels have a 4–6 record against the spread (ATS) over their last 10 games, indicating some inconsistency in covering spreads recently.

Padres Betting Trends

The Padres have an 8–2 ATS record over their past 10 games, reflecting strong performance in covering spreads recently.

Angels vs. Padres Matchup Trends

The Padres have been favorites in 20 games this season and won 15 (75%) of those contests.

Los Angeles Angels vs. San Diego Game Info

Los Angeles Angels vs San Diego starts on May 14, 2025 at 9:40 PM EST.

Spread: San Diego -1.5
Moneyline: Los Angeles Angels +156, San Diego -188
Over/Under: 9

Los Angeles Angels: (17-24)  |  San Diego: (26-15)

Remi's searched hard and found the best prop for this matchup: R. Vasquez under 21.5 Fantasy Score.. Prices move—always shop for the best number.

The Padres have been favorites in 20 games this season and won 15 (75%) of those contests.

LAA trend: The Angels have a 4–6 record against the spread (ATS) over their last 10 games, indicating some inconsistency in covering spreads recently.

SD trend: The Padres have an 8–2 ATS record over their past 10 games, reflecting strong performance in covering spreads recently.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Los Angeles Angels vs. San Diego Odds

AI algorithm Remi is pouring through tons of data points on each line. In fact, anytime the Los Angeles Angels vs San Diego trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme altitude can often follow normal, predictable betting trends.

Los Angeles Angels vs San Diego Opening Odds

LAA Moneyline: +156
SD Moneyline: -188
LAA Spread: +1.5
SD Spread: -1.5
Over/Under: 9

Los Angeles Angels vs San Diego Live Odds

Games PTS ML SPR O/U

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Los Angeles Angels Angels vs. San Diego Padres on May 14, 2025 at Petco Park.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
LAD@TOR TOR +1.5 56.7% 2 WIN
TOR@LAD TOR +1.5 55.3% 4 WIN
TOR@SEA OVER 7 54.9% 3 WIN
LAD@MIL UNDER 7.5 56.6% 6 WIN
TOR@NYY OVER 8 54.9% 4 WIN
TOR@NYY CARLOS RODON OVER 1.5 TOTAL WALKS ALLOWED 53.3% 3 WIN
NYY@TOR OVER 7.5 54.8% 2 WIN
LAD@PHI OVER 7 53.8% 3 WIN
SD@CHC CHC -109 53.8% 3 WIN
SD@CHC OVER 7.5 54.5% 4 LOSS
SD@CHC CHC -111 54.8% 4 LOSS
CIN@LAD SHOHEI OHTANI OVER 1.5 BASES 53.5% 3 WIN
BOS@NYY OVER 7 53.8% 3 LOSS
CIN@LAD ELLY DE LA CRUZ OVER 0.5 BASES 54.4% 4 LOSS
ARI@SD SD -131 57.3% 4 WIN
DET@BOS BOS -115 56.4% 5 WIN
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN