Cardinals vs. Phillies
Prediction, Odds & Props
May 12 | MLB AI Picks
Updated: 2025-05-10T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The St. Louis Cardinals and Philadelphia Phillies will face off on May 12, 2025, at Citizens Bank Park in Philadelphia. Both teams are looking to gain momentum as they navigate the early stages of the season.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: May 12, 2025
Start Time: 6:45 PM EST​
Venue: Citizens Bank Park​
Phillies Record: (24-16)
Cardinals Record: (22-19)
OPENING ODDS
STL Moneyline: +151
PHI Moneyline: -181
STL Spread: +1.5
PHI Spread: -1.5
Over/Under: 8
STL
Betting Trends
- The Cardinals have a 7-6 record against the spread (ATS) this season, indicating a slightly positive performance in covering the spread.
PHI
Betting Trends
- The Phillies have a 3-4 ATS record as the home team this season, reflecting challenges in covering the spread at Citizens Bank Park.
MATCHUP TRENDS
- The Cardinals have won 2 out of their last 3 games outright, showcasing their recent form and potential to cover the spread in upcoming matchups.
STL vs. PHI
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: A. Bohm over 5 Fantasy Score.
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St. Louis vs Philadelphia Prediction & Odds:
Free MLB Betting Insights for 5/12/25
The Cardinals, on the other hand, have shown flashes of their offensive ceiling, particularly when Nolan Arenado and Paul Goldschmidt are locked in and driving in runs, but their consistency has been undermined by injuries to the pitching staff and a bullpen that has struggled in high-leverage moments. Arenado is batting .310 with 8 home runs and 28 RBIs, while Goldschmidt is hitting .295 with 25 RBIs, and their veteran presence remains central to St. Louis’s hopes of stringing together a winning streak. However, the pitching staff, already stretched thin by Zack Thompson’s injury and underperformance from several rotation members, has put pressure on the offense to carry more of the load. The Cardinals are 8-10 on the road and will need a clean defensive effort and quality innings from their starter if they hope to keep pace with a Phillies team that feeds off the energy at home and has been punishing mistakes with consistency. For St. Louis to pull off a road win, they’ll have to neutralize the heart of Philadelphia’s order and find production from supporting bats like Lars Nootbaar and Brendan Donovan, who are capable of contributing but have been streaky at times. With Philadelphia’s home dominance and offensive depth giving them the edge on paper, this game will come down to whether St. Louis can hold firm on the mound, avoid falling behind early, and convert opportunities with runners on base—something they’ve struggled with in recent series—making Monday’s matchup a potential turning point for both clubs as the NL playoff race begins to take early shape.
That's a WWWWWWWWinner!! pic.twitter.com/xUMHPtpuz6
— St. Louis Cardinals (@Cardinals) May 11, 2025
St. Louis Cardinals MLB Preview
The St. Louis Cardinals enter their May 12 road matchup against the Philadelphia Phillies at a crucial early-season juncture, holding a 19-19 record and seeking consistency as they aim to stay competitive in a National League Central that remains up for grabs, with every game against top-tier opponents like the Phillies serving as a litmus test for their playoff ambitions. Despite flashes of offensive firepower and a talented core, the Cardinals have struggled to establish rhythm away from home, entering this game with a subpar 8-10 road record and a pitching staff that has been tested by injuries and underperformance. Offensively, the team continues to be carried by its veteran corner infielders, as Nolan Arenado is hitting .310 with 8 home runs and 28 RBIs, anchoring the lineup with clutch production and Gold Glove defense at third base, while Paul Goldschmidt remains a steady force with a .295 average and 25 RBIs, consistently giving the Cardinals competitive at-bats and timely contact. The supporting cast around them, including Lars Nootbaar and Brendan Donovan, has shown promise, but inconsistency and lack of depth have hampered the lineup’s ability to generate runs in bunches, particularly in the middle and bottom thirds of the order. Manager Oliver Marmol continues to experiment with lineup configurations and bullpen roles, especially with key arms like Zack Thompson sidelined and the rotation struggling to deliver consistent quality starts, placing added pressure on a bullpen that has faltered in late-inning scenarios.
The Cardinals have seen several leads slip away in the sixth and seventh innings, exposing a need for more reliable bridge relievers and highlighting the urgency to get more length from their starters to protect the back end of games. Against a Phillies team that thrives at home with a 13-3 record and a lineup that can punish mistakes, the Cardinals must play clean, efficient baseball—limiting walks, converting defensive opportunities, and taking advantage of any scoring chances they create. They’ll need Arenado and Goldschmidt to set the tone early, but contributions from Nootbaar, Donovan, and Tommy Edman will be just as critical if St. Louis hopes to keep pace with Philadelphia’s deep, balanced lineup. Plate discipline and situational hitting will be at a premium, as the Cardinals can’t afford to waste base runners or allow the game to spiral in a single inning, especially with Philadelphia’s bullpen excelling in protecting leads. This game represents more than just a chance to climb back above .500—it’s an opportunity for the Cardinals to show they can hang with one of the National League’s elite teams and prove that their veteran core, when supported properly, is still capable of leading a postseason push. To do that, they’ll need to overcome their recent road woes, trust their depth, and execute with the kind of sharpness that’s been missing during their 2025 campaign’s most frustrating stretches.

Credit: USA TODAY/IMAGN
Philadelphia Phillies MLB Preview
The Philadelphia Phillies return to Citizens Bank Park on May 12, 2025, looking to continue their early-season surge and defend their dominant home record as they welcome the St. Louis Cardinals for a key National League showdown, entering the game at 24-16 and just one game behind the division-leading Atlanta Braves in the NL East. The Phillies have been exceptional at home this season with a 13-3 record in South Philadelphia, feeding off an energized fanbase and executing at a high level in all facets of the game, thanks to a roster that blends veteran leadership with clutch hitting, a reliable rotation, and one of the most effective bullpens in baseball. Bryce Harper continues to be the focal point of the lineup, batting with authority and delivering in high-leverage moments, while Kyle Schwarber adds left-handed power that regularly changes the complexion of games with one swing. Alec Bohm and Bryson Stott have emerged as key contributors in the middle of the order, providing tough outs, contact hitting, and the ability to sustain innings, and the return to form of J.T. Realmuto has helped steady the lineup and improve the defensive command behind the plate.
Despite injuries to starters like Taijuan Walker, Philadelphia’s pitching staff has held strong with Zack Wheeler and Ranger Suárez carrying the rotation and keeping the team in every game through six or seven innings, supported by a bullpen that has been lights out in the late frames. JosĂ© Alvarado and Seranthony DomĂnguez have locked down the eighth and ninth innings with dominant stuff, and Jeff Hoffman has stepped up as a versatile option in middle relief, helping the Phillies neutralize rallies and strand runners when starters exit early. Manager Rob Thomson has managed matchups astutely, knowing when to play aggressively and when to lean on his pitching depth, and his ability to guide the team through adversity has paid dividends during stretches where injuries or slumps could have derailed the club’s rhythm. The Phillies enter this matchup against the Cardinals as favorites, not just because of their superior record but also due to the matchup advantages they hold offensively and defensively, particularly against a St. Louis team that has struggled on the road and has questions in both its rotation and bullpen. Philadelphia will look to jump out early, taking advantage of any shaky control from the Cardinals’ pitching staff, while relying on their bullpen to protect late-inning leads—a formula that has delivered consistent results all season. With their home dominance, offensive depth, and pitching reliability all trending in the right direction, the Phillies are poised to extend their strong play and secure another statement win against a team they may eventually have to battle in the National League playoff picture later this season.
Another Wheely good night on the mound pic.twitter.com/ZS78DvyhVd
— Philadelphia Phillies (@Phillies) May 12, 2025
St. Louis vs. Philadelphia Prop Picks (AI)
St. Louis vs. Philadelphia Prediction (AI)

Remi, our AI sports algorithm, has been pouring over mountains of data from every facet between the Cardinals and Phillies and using recursive machine learning and industry leading AI to analyze the data to a single cover probability.
Oddly enough, we’ve seen the AI has been most watching on the growing emphasis human bettors tend to put on player performance factors between a Cardinals team going up against a possibly unhealthy Phillies team. It appears the true game analytics might reflect a moderate lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.
Below is our current AI St. Louis vs Philadelphia picks, computer picks Cardinals vs Phillies, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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MLB | 9/26 | DET@BOS | UNLOCK THIS PICK | 5 |
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MLB | 9/26 | BAL@NYY | UNLOCK THIS PICK | 4 |
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MLB | 9/26 | ARI@SD | UNLOCK THIS PICK | 4 |
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MLB | 9/26 | NYM@MIA | UNLOCK THIS PICK | 1 |
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MLB | 9/26 | NYM@MIA | GET FREE PICK NOW | 1 | – | |
MLB | 9/26 | COL@SF | UNLOCK THIS PICK | 0 |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.
Cardinals Betting Trends
The Cardinals have a 7-6 record against the spread (ATS) this season, indicating a slightly positive performance in covering the spread.
Phillies Betting Trends
The Phillies have a 3-4 ATS record as the home team this season, reflecting challenges in covering the spread at Citizens Bank Park.
Cardinals vs. Phillies Matchup Trends
The Cardinals have won 2 out of their last 3 games outright, showcasing their recent form and potential to cover the spread in upcoming matchups.
St. Louis vs. Philadelphia Game Info
What time does St. Louis vs Philadelphia start on May 12, 2025?
St. Louis vs Philadelphia starts on May 12, 2025 at 6:45 PM EST.
Where is St. Louis vs Philadelphia being played?
Venue: Citizens Bank Park.
What are the opening odds for St. Louis vs Philadelphia?
Spread: Philadelphia -1.5
Moneyline: St. Louis +151, Philadelphia -181
Over/Under: 8
What are the records for St. Louis vs Philadelphia?
St. Louis: (22-19) Â |Â Philadelphia: (24-16)
What is the AI best bet for St. Louis vs Philadelphia?
Remi's searched hard and found the best prop for this matchup: A. Bohm over 5 Fantasy Score.. Prices move—always shop for the best number.
What are St. Louis vs Philadelphia trending bets?
The Cardinals have won 2 out of their last 3 games outright, showcasing their recent form and potential to cover the spread in upcoming matchups.
What are St. Louis trending bets?
STL trend: The Cardinals have a 7-6 record against the spread (ATS) this season, indicating a slightly positive performance in covering the spread.
What are Philadelphia trending bets?
PHI trend: The Phillies have a 3-4 ATS record as the home team this season, reflecting challenges in covering the spread at Citizens Bank Park.
Where can I find AI Picks for St. Louis vs Philadelphia?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
St. Louis vs. Philadelphia Odds
AI algorithm Remi is pouring through loads of stats on each player. In fact, anytime the St. Louis vs Philadelphia trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme temps can often follow normal, predictable patterns.
St. Louis vs Philadelphia Opening Odds
STL Moneyline:
+151 PHI Moneyline: -181
STL Spread: +1.5
PHI Spread: -1.5
Over/Under: 8
St. Louis vs Philadelphia Live Odds
Games | PTS | ML | SPR | O/U | |
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Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
Orioles
Yankees
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–
–
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+190
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+1.5 (-110)
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O 8.5 (-120)
U 8.5 (+100)
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Sep 27, 2025 2:21PM EDT
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Chicago Cubs
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–
–
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-180
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-1.5 (+115)
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O 9.5 (-105)
U 9.5 (-115)
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–
–
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+130
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+1.5 (-155)
-1.5 (+130)
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O 8.5 (-110)
U 8.5 (-110)
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Sep 27, 2025 4:06PM EDT
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Washington Nationals
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–
–
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+100
-120
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-1.5 (+165)
+1.5 (-200)
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O 8.5 (-110)
U 8.5 (-110)
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Sep 27, 2025 4:06PM EDT
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San Francisco Giants
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Rockies
Giants
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–
–
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+185
-225
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+1.5 (-110)
-1.5 (-110)
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O 8 (-105)
U 8 (-115)
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Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
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Mets
Marlins
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–
–
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-130
+110
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-1.5 (+125)
+1.5 (-150)
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O 8 (-115)
U 8 (-105)
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Sep 27, 2025 4:11PM EDT
Detroit Tigers
Boston Red Sox
9/27/25 4:11PM
Tigers
Red Sox
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–
–
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+125
-150
|
+1.5 (-180)
-1.5 (+150)
|
O 9 (+100)
U 9 (-120)
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Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
|
–
–
|
+170
-205
|
+1.5 (-120)
-1.5 (+100)
|
O 8.5 (-115)
U 8.5 (-105)
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Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
|
–
–
|
+125
-150
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+1.5 (-180)
-1.5 (+150)
|
O 8 (-105)
U 8 (-115)
|
|
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
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–
–
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+145
-175
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+1.5 (-155)
-1.5 (+130)
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O 8 (-110)
U 8 (-110)
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Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
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–
–
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+135
-165
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+1.5 (-180)
-1.5 (+150)
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O 7 (-120)
U 7 (+100)
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Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
|
–
–
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+115
-140
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+1.5 (-195)
-1.5 (+160)
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O 7.5 (-120)
U 7.5 (+100)
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Sep 27, 2025 9:39PM EDT
Houston Astros
Los Angeles Angels
9/27/25 9:39PM
Astros
Angels
|
–
–
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-165
+135
|
-1.5 (+105)
+1.5 (-125)
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O 9 (+100)
U 9 (-120)
|
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Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
|
–
–
|
+105
-125
|
+1.5 (-205)
-1.5 (+170)
|
O 7.5 (+105)
U 7.5 (-125)
|
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Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
|
–
–
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+100
-120
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-1.5 (+150)
+1.5 (-180)
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O 10 (-110)
U 10 (-110)
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MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers St. Louis Cardinals vs. Philadelphia Phillies on May 12, 2025 at Citizens Bank Park.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
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   LEAN |    %WIN |    UNITS | RESULT |
---|---|---|---|---|
NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
LAA@COL | COL +108 | 50.5% | 3 | WIN |
TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
KC@PHI | PHI -130 | 58.3% | 4 | WIN |
LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
KC@CLE | KC -104 | 52.0% | 3 | WIN |
CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |
PHI@NYM | OVER 8.5 | 55.6% | 4 | LOSS |
LAA@TEX | LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS | 54.1% | 4 | LOSS |
KC@CHW | KC -109 | 54.2% | 4 | WIN |
SD@SEA | DYLAN CEASE OVER 16.5 OUTS | 53.9% | 3 | LOSS |
SD@SEA | UNDER 8.5 | 54.4% | 4 | LOSS |
MIN@TOR | JOE RYAN UNDER 2.5 EARNED RUNS | 54.1% | 4 | LOSS |
SF@MIL | MIL +100 | 54.0% | 6 | LOSS |
TOR@MIA | MIA +1.5 | 62.0% | 6 | WIN |
CHC@LAA | OVER 9.5 | 54.9% | 4 | LOSS |
BOS@NYY | CARLOS RODON UNDER 4.5 HITS ALLOWED | 54.2% | 4 | WIN |
KC@DET | DET -115 | 56.1% | 5 | WIN |
CHC@LAA | LAA +1.5 | 57.6% | 5 | LOSS |
CIN@ARI | KEBRYAN HAYES STRIKEOUTS UNDER 0.5 | 56.2% | 6 | WIN |
LAD@SD | SD +110 | 50.9% | 6 | WIN |