Phillies vs. Guardians
Prediction, Odds & Props
May 11 | MLB AI Picks

Updated: 2025-05-09T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Philadelphia Phillies and Cleveland Guardians will conclude their three-game series at Progressive Field on Sunday, May 11, 2025, with both teams holding identical 23-16 records. The Phillies aim to secure the series win after a dominant 7-1 victory on Saturday, while the Guardians look to bounce back and defend their strong home record.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: May 11, 2025

Start Time: 7:10 PM EST​

Venue: Progressive Field​

Guardians Record: (23-16)

Phillies Record: (23-16)

OPENING ODDS

PHI Moneyline: -170

CLE Moneyline: +143

PHI Spread: -1.5

CLE Spread: +1.5

Over/Under: 7.5

PHI
Betting Trends

  • The Phillies have a 5-5 record against the spread (ATS) over their last 10 games, indicating a balanced performance in recent matchups.

CLE
Betting Trends

  • The Guardians have covered the spread in 4 of their last 5 home games, showcasing strong performance at Progressive Field.

MATCHUP TRENDS

  • The total has gone UNDER in 10 of the Phillies’ last 12 games, while the Guardians have seen the total go UNDER in 4 of their last 5 games, suggesting a trend towards low-scoring contests.

PHI vs. CLE
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: J. Ramirez over 5.5 Fantasy Score.

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Philadelphia vs Cleveland Prediction & Odds:
Free MLB Betting Insights for 5/11/25

The Philadelphia Phillies and Cleveland Guardians will square off in the finale of their three-game interleague series on Sunday, May 11, 2025, at Progressive Field in a matchup between two evenly matched 23-16 clubs that are each vying for early-season control of their respective divisions. The Phillies delivered a convincing 7-1 win on Saturday, riding a dominant start from their pitching staff and an offensive outburst that included a three-hit performance and a two-run homer from Bryce Harper, who continues to set the tone for a lineup that has averaged 5.7 runs per game over its last 10 contests. Harper, alongside Trea Turner and Kyle Schwarber, forms a formidable top half of the batting order that punishes mistakes and extends innings with power and patience, creating sustained pressure on opposing starters. Sunday’s pitching matchup will feature Philadelphia’s Zack Wheeler (3-1, 3.35 ERA), who has looked sharp through the first month and a half of the season with above-average velocity, an excellent WHIP, and the ability to pitch deep into games, facing off against Cleveland’s Luis Ortiz (2-3, 5.30 ERA), who has been inconsistent and vulnerable to the long ball, struggling to keep the Guardians in games when facing lineups with elite power. Ortiz will be under pressure to limit traffic early, as the Phillies have shown the ability to score in bunches, especially in the middle innings, where they often break open close games with extra-base hits and aggressive base running.

While Cleveland’s offense is capable, averaging just over 4.3 runs per game, they lack the home-run threat of their opponent and will instead look to small ball and situational hitting to claw back into the series; José Ramírez remains their most reliable weapon with a .278 average and six home runs, while Steven Kwan provides a spark from the leadoff spot with a .333 average and excellent plate discipline. The Guardians’ best hope may rest in playing clean defense and taking advantage of any early mistakes from Wheeler to keep the game close into the later innings, where their bullpen has shown the ability to limit damage with effective righty-lefty matchups. Defensively, both teams have been solid, but the Phillies’ superior infield range and error prevention have made them one of the league’s better defensive clubs, and that could be a deciding factor in a tight, low-scoring affair. Both teams have trended heavily toward the under in recent weeks, with the total going under in 10 of the Phillies’ last 12 and four of Cleveland’s last five games, suggesting that pitching and defense may once again take center stage on Sunday. With both teams tied in the standings and boasting similar win profiles, the rubber match carries significant weight in terms of momentum heading into the next week, and if the Phillies continue their current trend of capitalizing on early opportunities while trusting their deep rotation and lockdown bullpen, they could leave Cleveland with a critical series win and further solidify their place among the National League’s elite.

Philadelphia Phillies MLB Preview

The Philadelphia Phillies enter Sunday’s series finale at Progressive Field with an opportunity to secure an important road series victory against the Cleveland Guardians and continue building on what has been a quietly dominant stretch of baseball, as they sit at 23-16 and tied with Cleveland in the standings but trending upward thanks to a balanced roster, consistent pitching, and a lineup that has been heating up over the past two weeks. Coming off a 7-1 win on Saturday, the Phillies are riding the momentum of a potent offensive performance led by Bryce Harper, who finished the night with three hits including a two-run homer that set the tone early and continued his push to reassert himself as one of the game’s premier middle-of-the-order bats. Harper has been especially dangerous against right-handed pitching and should again be the focal point against Cleveland starter Luis Ortiz, whose 5.30 ERA and trouble limiting hard contact have made him vulnerable to quick-strike offenses like Philadelphia’s. The Phillies have received strong complementary production from Trea Turner, who continues to reach base at an elite clip while stealing bases and setting the table, and Kyle Schwarber, who remains a threat to go deep every time he steps in the box and has been particularly effective in driving in runs with less than two outs. That top-three of the order, combined with solid situational hitting from the likes of Alec Bohm and J.T. Realmuto, gives the Phillies one of the most well-rounded offenses in the National League, averaging nearly six runs per game over their last 10 contests.

On the mound, Zack Wheeler will get the start and brings a 3-1 record with a 3.35 ERA into the matchup, having delivered quality starts in five of his last six appearances with a fastball that remains in the mid-to-upper 90s and a wipeout slider that has generated swings and misses at an elite rate. Wheeler’s ability to work deep into games has saved the bullpen during tight stretches, and his command and rhythm with Realmuto make him a difficult puzzle to solve for even the most patient lineups. The Phillies’ bullpen, meanwhile, has been excellent in recent weeks, sporting a sub-3.30 ERA over the last 10 games and doing a good job of preserving late leads while maintaining excellent strikeout-to-walk ratios. Defensively, the Phillies have played sharp, error-free baseball, particularly up the middle with Bryson Stott and Turner forming a steady double-play combination and Harper’s underrated outfield range saving runs in right field. Philadelphia has also been strong against the spread, holding steady at 5-5 over their last 10 while consistently staying under in total runs, largely due to their improved pitching and ability to execute with runners on base. If Wheeler pitches to his typical standard and the offense continues to capitalize on Ortiz’s early-inning struggles, the Phillies are in excellent shape to take the rubber match and leave Cleveland with a series win, another step forward for a team that looks increasingly built to contend in October.

The Philadelphia Phillies and Cleveland Guardians will conclude their three-game series at Progressive Field on Sunday, May 11, 2025, with both teams holding identical 23-16 records. The Phillies aim to secure the series win after a dominant 7-1 victory on Saturday, while the Guardians look to bounce back and defend their strong home record. Philadelphia vs Cleveland AI Prediction: Free MLB Betting Insights for May 11. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Cleveland Guardians MLB Preview

The Cleveland Guardians head into Sunday’s series finale against the Philadelphia Phillies looking to protect their home field and avoid dropping a key interleague series, entering the matchup at 23-16 and tied with the Phillies in the standings but having lost momentum following Saturday’s 7-1 defeat in which their offense was largely shut down and their pitching staff struggled to contain Philadelphia’s power. Despite an impressive 12-6 home record, Cleveland’s success has largely come from clean defense, timely hitting, and a resilient pitching staff, but those traits were lacking in Game 2, and the team now turns to Luis Ortiz on the mound to try and reset the tone before the Phillies can complete the series win. Ortiz, who enters the game with a 2-3 record and a 5.30 ERA, has shown flashes of effectiveness but has also been inconsistent, especially when facing lineups that can jump on his early pitches and force him into long counts or high pitch totals before the fifth inning. He will be tasked with containing a Phillies lineup that has produced multiple runs in the early innings throughout the series, led by Bryce Harper, who homered again on Saturday and continues to be one of the most dangerous left-handed hitters in the league, particularly against right-handed pitching.

Offensively, the Guardians average 4.32 runs per game and will need their core group—namely José Ramírez and Steven Kwan—to set the tone against Zack Wheeler, who brings a 3.35 ERA and a strong reputation for working deep into games. Kwan has been Cleveland’s most consistent hitter with a .333 average and excellent strike-zone awareness, often providing table-setting value in the first two innings, while Ramírez remains the heart of the lineup with his combination of switch-hitting power and clutch RBI production. Daniel Schneemann and Gabriel Arias have also chipped in with timely hits during Cleveland’s recent surge, but the Guardians still struggle at times to produce extra-base hits and have relied more on contact and situational execution than pure slugging. Defensively, Cleveland has played with consistency, ranking near the top of the American League in fielding percentage and having committed just a handful of errors over the past two weeks, but they’ll need a sharp performance to support Ortiz, who has not pitched deep into games in recent outings. Their bullpen has generally been a strength, with reliable arms in the seventh through ninth innings, but recent usage and high pitch counts may limit their flexibility if Ortiz cannot give them length. With both teams tied in their divisions and aiming to keep pace with rivals, Sunday’s contest represents more than just a rubber match—it’s a tone-setting opportunity that could impact confidence and rhythm for the next stretch of the season. If Ortiz can manage five solid innings and the offense strikes early against Wheeler, Cleveland has the ingredients to salvage the finale and reinforce its reputation as one of the most competitive, fundamentally sound clubs in the AL Central.

Philadelphia vs. Cleveland Prop Picks (AI)

AI algorithm Remi is pouring through tons of data on each line. In fact, anytime the Phillies and Guardians play there’s always several intriguing angles to key in on. Not to mention games played at Progressive Field in May rarely follow normal, predictable patterns.
Remi's searched hard and found the best prop for this matchup: J. Ramirez over 5.5 Fantasy Score.

Philadelphia vs. Cleveland Prediction (AI)

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Remi, our AI sports algorithm, has been pouring over mountains of data from every angle between the Phillies and Guardians and using recursive machine learning and industry leading AI to examine the data to a single cover probability.

Oddly enough, we’ve seen the AI has been most fixated on the linear correlation of factor knucklehead sportsbettors regularly put on coaching factors between a Phillies team going up against a possibly rested Guardians team. In reality, the true game analytics appear to reflect a moderate lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI Philadelphia vs Cleveland picks, computer picks Phillies vs Guardians, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
MLB 9/26 DET@BOS UNLOCK THIS PICK 5 EXECUTIVE Locked EXECUTIVE
MLB 9/26 BAL@NYY UNLOCK THIS PICK 4 INTEL Locked INTEL
MLB 9/26 ARI@SD UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
MLB 9/26 NYM@MIA UNLOCK THIS PICK 1 INTEL Locked INTEL
MLB 9/26 NYM@MIA GET FREE PICK NOW 1
MLB 9/26 COL@SF UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Phillies Betting Trends

The Phillies have a 5-5 record against the spread (ATS) over their last 10 games, indicating a balanced performance in recent matchups.

Guardians Betting Trends

The Guardians have covered the spread in 4 of their last 5 home games, showcasing strong performance at Progressive Field.

Phillies vs. Guardians Matchup Trends

The total has gone UNDER in 10 of the Phillies’ last 12 games, while the Guardians have seen the total go UNDER in 4 of their last 5 games, suggesting a trend towards low-scoring contests.

Philadelphia vs. Cleveland Game Info

Philadelphia vs Cleveland starts on May 11, 2025 at 7:10 PM EST.

Spread: Cleveland +1.5
Moneyline: Philadelphia -170, Cleveland +143
Over/Under: 7.5

Philadelphia: (23-16)  |  Cleveland: (23-16)

Remi's searched hard and found the best prop for this matchup: J. Ramirez over 5.5 Fantasy Score.. Prices move—always shop for the best number.

The total has gone UNDER in 10 of the Phillies’ last 12 games, while the Guardians have seen the total go UNDER in 4 of their last 5 games, suggesting a trend towards low-scoring contests.

PHI trend: The Phillies have a 5-5 record against the spread (ATS) over their last 10 games, indicating a balanced performance in recent matchups.

CLE trend: The Guardians have covered the spread in 4 of their last 5 home games, showcasing strong performance at Progressive Field.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Philadelphia vs. Cleveland Odds

AI algorithm Remi is pouring through loads of data points on each line. In fact, anytime the Philadelphia vs Cleveland trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme altitude seemingly never follow normal, predictable patterns.

Philadelphia vs Cleveland Opening Odds

PHI Moneyline: -170
CLE Moneyline: +143
PHI Spread: -1.5
CLE Spread: +1.5
Over/Under: 7.5

Philadelphia vs Cleveland Live Odds

Games PTS ML SPR O/U
Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
Orioles
Yankees
+195
-218
+1.5 (-109)
-1.5 (-105)
O 8.5 (-124)
U 8.5 (+108)
Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
 
-168
 
-1.5 (+118)
O 9 (-119)
U 9 (+104)
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
+138
-152
+1.5 (-152)
-1.5 (+134)
O 8.5 (-113)
U 8.5 (-102)
Sep 27, 2025 4:06PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:06PM
White Sox
Nationals
+104
-115
+1.5 (-198)
-1.5 (+174)
O 8.5 (-107)
U 8.5 (-107)
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
+195
-218
+1.5 (-107)
-1.5 (-107)
O 8 (+101)
U 8 (-116)
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
-128
+116
-1.5 (+129)
+1.5 (-146)
O 8 (-112)
U 8 (-103)
Sep 27, 2025 4:11PM EDT
Detroit Tigers
Boston Red Sox
9/27/25 4:11PM
Tigers
Red Sox
+116
-128
+1.5 (-184)
-1.5 (+162)
O 9 (+107)
U 9 (-123)
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
+180
-200
+1.5 (-117)
-1.5 (+103)
O 8.5 (-107)
U 8.5 (-107)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+120
-132
+1.5 (-183)
-1.5 (+161)
O 7.5 (-120)
U 7.5 (+105)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+153
-169
+1.5 (-141)
-1.5 (+125)
O 8 (-102)
U 8 (-113)
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
+128
-141
+1.5 (-183)
-1.5 (+161)
O 7 (-118)
U 7 (+103)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+122
-135
+1.5 (-177)
-1.5 (+156)
O 7.5 (-113)
U 7.5 (-102)
Sep 27, 2025 9:39PM EDT
Houston Astros
Los Angeles Angels
9/27/25 9:39PM
Astros
Angels
-140
+127
-1.5 (+116)
+1.5 (-131)
O 9 (-107)
U 9 (-107)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+113
-125
+1.5 (-197)
-1.5 (+173)
O 7 (-116)
U 7 (+101)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
+104
-115
+1.5 (-190)
-1.5 (+166)
O 10 (-115)
U 10 (+100)

MLB Past Picks

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We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Philadelphia Phillies vs. Cleveland Guardians on May 11, 2025 at Progressive Field.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS
CIN@ARI KEBRYAN HAYES STRIKEOUTS UNDER 0.5 56.2% 6 WIN
LAD@SD SD +110 50.9% 6 WIN