Padres vs. Rockies
Prediction, Odds & Props
May 10 | MLB AI Picks

Updated: 2025-05-08T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The San Diego Padres and Colorado Rockies will face off on Saturday, May 10, 2025, at Coors Field in Denver. The Padres, currently leading the NL West, aim to continue their dominance against a struggling Rockies team.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: May 10, 2025

Start Time: 8:10 PM EST​

Venue: Coors Field​

Rockies Record: (6-32)

Padres Record: (24-13)

OPENING ODDS

SD Moneyline: -207

COL Moneyline: +172

SD Spread: -1.5

COL Spread: +1.5

Over/Under: 11.5

SD
Betting Trends

  • The Padres have a 23-13 record against the spread (ATS) this season.

COL
Betting Trends

  • The Rockies have a 6-31 record against the spread (ATS) this season.

MATCHUP TRENDS

  • The Padres have covered the spread in 5 of their last 7 meetings against the Rockies.

SD vs. COL
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: A. Amador under 5.5 Fantasy Score.

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San Diego vs Colorado Prediction & Odds:
Free MLB Betting Insights for 5/10/25

The San Diego Padres and Colorado Rockies are set to meet on Saturday, May 10, 2025, at Coors Field in what appears to be a lopsided National League West matchup based on early-season form, with San Diego entering at 23-13 and leading the division while Colorado continues to sink with a league-worst 6-31 record. The Padres are currently riding a four-game winning streak and most recently lit up Colorado’s pitching staff for 13 runs in a 13-9 victory, showcasing the depth and power of a rejuvenated lineup. Gavin Sheets and Martín Maldonado both had major impacts in that game, with Sheets driving in four runs and Maldonado adding a home run that helped extend an early lead. San Diego’s success hasn’t just come from the offense, though, as the pitching staff has been equally sharp—Saturday’s starter Stephen Kolek has been lights out in limited action, entering with a 1-0 record and a 0.00 ERA through his appearances so far.

The Padres are built on a foundation of veteran leadership, aggressive baserunning, and clean defense, and they’ve executed that formula well throughout April and into May. Meanwhile, Colorado continues to spiral, coming off yet another loss that highlighted all of their current deficiencies—poor starting pitching, leaky defense, and a lack of offensive rhythm outside of the occasional home-field Coors Field boost. Saturday’s starter Bradley Blalock enters with a bloated 8.03 ERA and has struggled to keep hitters off base, especially when pitching out of the stretch. The Rockies’ bullpen has offered little relief, and defensively, they have committed multiple costly errors that have extended innings and compounded their pitching issues. With San Diego owning the clear advantage in almost every statistical category—batting average, ERA, home run differential, and fielding percentage—the biggest challenge for the Padres may simply be avoiding complacency and staying locked in on the road. Historically, they’ve covered the spread in five of their last seven games against the Rockies, and with the Rockies now just 6-31 ATS on the year, trends are heavily in San Diego’s favor. Expect San Diego to be aggressive early, push for a big inning against Blalock, and then hand things over to a bullpen that has been far more reliable than Colorado’s. Unless the Rockies can find unexpected brilliance from their starter or capitalize on Coors Field’s unique offensive environment, the Padres look primed to extend their winning streak and further cement their place atop the division.

San Diego Padres MLB Preview

The San Diego Padres enter Saturday’s contest against the Rockies as one of the hottest teams in baseball, owning a 23-13 record and carrying a four-game winning streak fueled by explosive offense and dependable pitching. San Diego’s recent 13-9 win over Colorado showcased the firepower of a lineup that’s clicking on all cylinders, with Gavin Sheets driving in four runs and Martín Maldonado adding a homer that helped bury the Rockies early. The Padres’ offense has been deep and balanced, getting contributions up and down the order, and their ability to manufacture runs through both power and situational hitting has made them a matchup nightmare for struggling pitching staffs like Colorado’s. On the mound, Saturday starter Stephen Kolek brings a sparkling 0.00 ERA into the game through limited action so far, and the Padres will look for him to continue setting the tone early and bridging to a bullpen that has held its own. Defensively, San Diego has been sharp, reducing errors and turning double plays efficiently—important traits when playing at Coors Field, where batted balls find grass easily and long innings can snowball.

The Padres have also dominated betting trends, going 23-13 ATS and covering in five of their last seven games against the Rockies, including multiple high-scoring wins. With the top of the NL West in their sights and a favorable stretch of games ahead, San Diego knows that taking care of business against the bottom-feeding Rockies is essential, not just to stay in first place but to keep building momentum into the summer. Manager Mike Shildt has the club firing on all cylinders with a strong balance of veteran leadership and hungry young talent, and Saturday presents a perfect opportunity to further widen the gap in the division. With everything pointing in their favor—matchup history, starting pitching, bullpen depth, and offensive form—the Padres enter this game with confidence and a clear expectation to win and do so decisively.

The San Diego Padres and Colorado Rockies will face off on Saturday, May 10, 2025, at Coors Field in Denver. The Padres, currently leading the NL West, aim to continue their dominance against a struggling Rockies team. San Diego vs Colorado AI Prediction: Free MLB Betting Insights for May 10. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Colorado Rockies MLB Preview

The Colorado Rockies return to Coors Field for Saturday’s matchup with the San Diego Padres holding the league’s worst record at 6-31 and facing mounting pressure as each series seems to widen the gap between them and the rest of the National League. Despite the familiar offensive boosts that come with playing in the altitude of Denver, the Rockies have failed to convert that into consistent scoring, frequently falling behind early and placing excessive strain on a pitching staff that ranks near the bottom in ERA, WHIP, and home runs allowed. Bradley Blalock is expected to take the mound Saturday and brings an 0-1 record and an 8.03 ERA into the outing, reflecting his ongoing struggles with command and efficiency through short starts. Colorado’s offense has had bright spots in spurts, especially when players like Nolan Jones or Brendan Rodgers manage to square up pitches, but the lineup lacks depth and has been highly vulnerable with runners in scoring position. Defensively, the Rockies have not helped their cause either, with repeated errors and misplays contributing to lopsided innings and further unraveling efforts by the pitching staff to remain competitive.

The bullpen has failed to hold even modest leads or ties, frequently giving up late runs that deflate any potential for comeback efforts. As a team, the Rockies are currently 6-31 ATS, an almost shocking number that speaks to just how often they’ve been outmatched both outright and against betting lines. Manager Bud Black has continued to push development for younger players, but morale is slipping and signs of on-field improvement are scarce. Facing a division-leading Padres club that is deep in both offense and pitching, Colorado’s clearest path to a competitive game would be to jump out to an early lead, lean into Coors Field’s power potential, and hope for a rare clean outing from the rotation and bullpen. However, recent matchups show the Padres’ offense has handled the Rockies’ pitching with ease, and without significant adjustments, it’s hard to envision a different outcome. Saturday’s game represents another uphill battle for a team desperate to find anything positive to build upon during an already long season.

San Diego vs. Colorado Prop Picks (AI)

AI algorithm Remi is pouring through loads of data on each team. In fact, anytime the Padres and Rockies play there’s always several intriguing trends to key in on. Not to mention games played at Coors Field in May can often follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: A. Amador under 5.5 Fantasy Score.

San Diego vs. Colorado Prediction (AI)

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Remi, our AI sports genius, has been pouring over tons of data from every past game between the Padres and Rockies and using recursive machine learning and kick-ass AI to analyze the data to a single cover probability.

Remi has been most fixated on the trending emphasis emotional bettors often put on Colorado’s strength factors between a Padres team going up against a possibly healthy Rockies team. We’ve found the true game analytics might reflect a strong lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI San Diego vs Colorado picks, computer picks Padres vs Rockies, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Padres Betting Trends

The Padres have a 23-13 record against the spread (ATS) this season.

Rockies Betting Trends

The Rockies have a 6-31 record against the spread (ATS) this season.

Padres vs. Rockies Matchup Trends

The Padres have covered the spread in 5 of their last 7 meetings against the Rockies.

San Diego vs. Colorado Game Info

San Diego vs Colorado starts on May 10, 2025 at 8:10 PM EST.

Spread: Colorado +1.5
Moneyline: San Diego -207, Colorado +172
Over/Under: 11.5

San Diego: (24-13)  |  Colorado: (6-32)

Remi's searched hard and found the best prop for this matchup: A. Amador under 5.5 Fantasy Score.. Prices move—always shop for the best number.

The Padres have covered the spread in 5 of their last 7 meetings against the Rockies.

SD trend: The Padres have a 23-13 record against the spread (ATS) this season.

COL trend: The Rockies have a 6-31 record against the spread (ATS) this season.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

San Diego vs. Colorado Odds

AI algorithm Remi is pouring through loads of data on each line. In fact, anytime the San Diego vs Colorado trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme travel distance seemingly never follow normal, predictable betting trends.

San Diego vs Colorado Opening Odds

SD Moneyline: -207
COL Moneyline: +172
SD Spread: -1.5
COL Spread: +1.5
Over/Under: 11.5

San Diego vs Colorado Live Odds

Games PTS ML SPR O/U
In Progress
Baltimore Orioles
New York Yankees
In Progress
Orioles
Yankees
0
3
+950
-2000
+3.5 (+100)
-3.5 (-130)
O 6.5 (-140)
U 6.5 (+105)
In Progress
St Louis Cardinals
Chicago Cubs
In Progress
Cardinals
Cubs
0
0
 
-185
 
-1.5 (+105)
O 9.5 (-125)
U 9.5 (-105)
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
+140
-170
+1.5 (-155)
-1.5 (+130)
O 8.5 (-105)
U 8.5 (-115)
Sep 27, 2025 4:05PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:05PM
White Sox
Nationals
-105
-115
-1.5 (+150)
+1.5 (-180)
O 8.5 (-115)
U 8.5 (-105)
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
+190
-235
+1.5 (-105)
-1.5 (-115)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
-140
+115
-1.5 (+125)
+1.5 (-150)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 4:11PM EDT
Detroit Tigers
Boston Red Sox
9/27/25 4:11PM
Tigers
Red Sox
+105
-125
-1.5 (+165)
+1.5 (-200)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
+175
-215
+1.5 (-115)
-1.5 (-105)
O 8.5 (-115)
U 8.5 (-105)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+110
-130
+1.5 (-195)
-1.5 (+160)
O 8 (-110)
U 8 (-110)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+145
-175
+1.5 (-150)
-1.5 (+125)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
+120
-145
+1.5 (-190)
-1.5 (+155)
O 7 (-120)
U 7 (+100)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+115
-140
+1.5 (-180)
-1.5 (+150)
O 7.5 (-120)
U 7.5 (+100)
Sep 27, 2025 9:39PM EDT
Houston Astros
Los Angeles Angels
9/27/25 9:39PM
Astros
Angels
-145
+120
-1.5 (+110)
+1.5 (-130)
O 9 (-110)
U 9 (-110)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+100
-120
-1.5 (+175)
+1.5 (-215)
O 7 (-115)
U 7 (-105)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
+100
-120
-1.5 (+150)
+1.5 (-180)
O 10 (-115)
U 10 (-105)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers San Diego Padres vs. Colorado Rockies on May 10, 2025 at Coors Field.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
ARI@SD SD -131 57.3% 4 WIN
DET@BOS BOS -115 56.4% 5 WIN
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS