Brewers vs. White Sox
Prediction, Odds & Props
May 01 | MLB AI Picks

Updated: 2025-04-29T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Milwaukee Brewers and Chicago White Sox conclude their three-game series on May 1, 2025, at Guaranteed Rate Field. The Brewers aim to secure a series sweep, while the White Sox look to salvage the final game and end their losing streak.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: May 01, 2025

Start Time: 2:10 PM EST​

Venue: Rate Field​

White Sox Record: (7-23)

Brewers Record: (16-15)

OPENING ODDS

MIL Moneyline: -181

CHW Moneyline: +150

MIL Spread: -1.5

CHW Spread: +1.5

Over/Under: 8.5

MIL
Betting Trends

  • The Brewers are 5–2 against the spread (ATS) in their last seven games, showcasing strong performance in covering the run line.

CHW
Betting Trends

  • The White Sox have struggled ATS, with a record of 7–21 overall, indicating challenges in covering the run line consistently.

MATCHUP TRENDS

  • The Brewers are favored with a moneyline of -181, while the White Sox are underdogs at +150; the over/under is set at 8.5 runs.

MIL vs. CHW
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: L. Robert over 0.5 Total Bases.

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Milwaukee vs Chicago White Sox Prediction & Odds:
Free MLB Betting Insights for 5/1/25

The Milwaukee Brewers and Chicago White Sox are set to conclude their interleague series on May 1, 2025, at Guaranteed Rate Field, with the Brewers eyeing a sweep and the White Sox desperate to salvage the finale and break out of a dismal early-season slide. Milwaukee, sitting at 14–15, has picked up momentum with back-to-back wins in this series and has found success behind a balanced combination of disciplined at-bats, solid pitching, and a few timely hits that have proven just enough against a floundering White Sox club. The Brewers will send right-hander Chad Patrick to the mound, who has been one of the team’s most effective arms so far in 2025, posting a 2.45 ERA despite a 1–2 record, thanks to limited run support. Patrick’s ability to limit baserunners and work deep into games has given Milwaukee some much-needed stability, and he’ll face a White Sox lineup that enters the finale ranked last in Major League Baseball in both batting average and OBP, struggling mightily to generate any offense. Opposing him will be Chicago starter Sean Burke, who has endured a rough start to the season, entering with a 1–4 record and a ballooning 6.00 ERA—indicative of both command issues and lack of run support. Milwaukee’s lineup, led by Brice Turang and Sal Frelick, has quietly developed into a pesky group that gets on base, manufactures runs with speed and contact, and plays fundamentally sound baseball.

Turang leads the team with a .317 average and .368 OBP, while Frelick has chipped in with a .302 mark and .383 OBP, providing the Brewers with two top-of-the-order threats capable of setting the tone early. The White Sox, by contrast, continue to spiral with a 7–21 record, plagued by one of the league’s least productive offenses and a pitching staff that simply hasn’t been able to keep them in games. Chicago’s team ERA sits at 4.68, and its WHIP of 1.437 reflects the volume of traffic their pitchers allow—giving opponents too many chances to score and forcing the offense to play from behind nearly every night. Despite some flashes of potential from players like Andrew Benintendi and Miguel Vargas, the lineup lacks the depth and discipline to sustain rallies or capitalize in clutch situations. As such, the White Sox find themselves in danger of yet another sweep at home, and unless their bats come alive quickly, it’s hard to envision them overcoming Milwaukee’s momentum and solid pitching. The Brewers are favored heading into this contest, with sportsbooks leaning heavily toward them based on current form and statistical edge, while the over/under of 8.5 reflects skepticism that Chicago can generate much offense on their end. For Milwaukee, this game is an opportunity to claw back to .500 and continue building confidence as they prepare for tougher opponents in the NL Central. For Chicago, it’s about pride, course correction, and hopefully sparking something that can halt their early-season tailspin. Given the contrast in form, pitching matchups, and morale, the finale strongly favors the visitors unless the White Sox deliver their sharpest performance yet.

Milwaukee Brewers MLB Preview

The Milwaukee Brewers arrive at Guaranteed Rate Field with a chance to complete a three-game sweep of the Chicago White Sox and inch their way back to .500 after what has been a roller-coaster opening stretch to the 2025 season. With a 14–15 record entering the finale, the Brewers have shown promising signs of cohesion and resilience, fueled by improved starting pitching and reliable contact hitting. Chad Patrick will take the mound in this matchup, and while his 1–2 record may not turn heads, his 2.45 ERA and steady presence have been a major boost for Milwaukee. Patrick has kept hard contact to a minimum and consistently worked into the middle innings, providing length that has taken pressure off a bullpen that has already logged its share of early-season innings. The Brewers will look to give Patrick more run support this time around, something that’s been inconsistent at times but is trending in the right direction thanks to the contributions of a lineup that is starting to find its rhythm. Leading the offensive charge are Brice Turang and Sal Frelick, both of whom are hitting over .300 and getting on base at impressive clips—.368 and .383 OBP respectively. Turang’s patient approach at the plate and ability to swipe bags has given the Brewers an edge in tight games, while Frelick’s consistency has offered needed balance in the top half of the order.

Although the power numbers across the lineup have been modest, Milwaukee has embraced a grind-it-out identity, manufacturing runs with speed, contact, and timely hitting rather than relying solely on the long ball. That approach has served them well in this series, particularly against a White Sox team that has allowed a steady stream of baserunners and struggled with control on the mound. The Brewers have also flashed solid defense behind their pitchers, making the routine plays and turning key double plays to escape jams—something that has further highlighted their sharp contrast to a mistake-prone Chicago club. With a chance to sweep, the Brewers’ formula remains simple: aggressive base running, disciplined at-bats, and continued stability from the mound and bullpen. This series finale presents a valuable opportunity for Milwaukee to finish strong before returning to face stiffer competition in the NL Central, and doing so with a three-game win streak could be a psychological turning point. Against a White Sox starter like Sean Burke, who’s carrying a 6.00 ERA into the game, the Brewers will be aggressive early, looking to drive up pitch counts and force Chicago’s shaky bullpen into action by the middle innings. A win would move the Brewers one step closer to reestablishing themselves as contenders in the division, and more importantly, reinforce that their balanced, team-first style of play can hold up even on the road. If Patrick delivers another quality start and the top of the lineup continues to set the table, Milwaukee is well-positioned to capitalize and head home with a sweep in hand.

The Milwaukee Brewers and Chicago White Sox conclude their three-game series on May 1, 2025, at Guaranteed Rate Field. The Brewers aim to secure a series sweep, while the White Sox look to salvage the final game and end their losing streak. Milwaukee vs Chicago White Sox AI Prediction: Free MLB Betting Insights for May 01. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Chicago White Sox White Sox MLB Preview

The Chicago White Sox enter the final game of their series against the Milwaukee Brewers looking to halt a downward spiral that has defined their 2025 season thus far. At 7–21, the White Sox are entrenched at the bottom of the American League standings, and the numbers bear out their struggles across every phase of the game. Their offense has been one of the least productive in baseball, with a team batting average of .221 and a meager .278 OBP—both metrics that underscore their inability to consistently get runners aboard or advance them into scoring position. Even in favorable hitting counts, the White Sox have struggled to convert, often failing to string together hits or capitalize on rare scoring opportunities. The team has found minimal rhythm through any one part of the lineup, although occasional bright spots have come from the likes of Andrew Benintendi, who continues to flash veteran-level plate discipline and some timely hitting, and Miguel Vargas, who has shown flashes of offensive upside. Still, Chicago’s inability to extend innings or put sustained pressure on opposing pitchers has resulted in frequent low-scoring losses and mounting frustration. Taking the mound for the White Sox is right-hander Sean Burke, whose 1–4 record and 6.00 ERA serve as a reflection of the team’s broader pitching woes. Burke has struggled to find consistency with his command, issuing too many walks and often finding himself pitching from behind in counts. That lack of control has led to bloated pitch counts and early exits, overexposing a bullpen that has been unable to mask the team’s starting rotation issues.

Defensively, the White Sox have failed to provide any meaningful support for their pitchers, with one of the league’s higher WHIPs at 1.437 and a tendency to commit poorly timed mistakes that extend innings and add pressure to an already taxed staff. The starting rotation’s inability to pitch deep into games has placed a tremendous burden on the relief corps, which lacks the depth or high-leverage performers to consistently hold close leads or keep blowouts in check. Manager Pedro Grifol is running out of buttons to push as the team continues to underperform, and the mood around the club is one of urgency, bordering on desperation. In this finale against Milwaukee, the White Sox will need a near-flawless performance to avoid a sweep and begin rebuilding momentum for the remainder of the season. It will start with Burke setting the tone by attacking the strike zone and minimizing free passes, while the offense must find a way to capitalize on any early scoring chances against Brewers starter Chad Patrick. Manufacturing runs through small ball, aggressive base running, and timely situational hitting may be the only path to staying competitive given their power outage. This game offers a critical opportunity—not only to snap a losing streak but to prove the club still has fight left and can begin the long climb out of the basement. If the White Sox can pair a rare strong start with a composed defensive effort and some lineup cohesion, they may finally steal a much-needed win and avoid another demoralizing sweep at home.

Milwaukee vs. Chicago White Sox Prop Picks (AI)

Remi is pouring through tons of datapoints on each player. In fact, anytime the Brewers and White Sox play there’s always several intriguing observations to key in on. Not to mention games played at Rate Field in May seemingly never follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: L. Robert over 0.5 Total Bases.

Milwaukee vs. Chicago White Sox Prediction (AI)

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Remi, our AI sports wizard, has been pouring over mountains of data from every past game between the Brewers and White Sox and using recursive machine learning and kick-ass AI to examine the data to a single cover probability.

Interestingly enough, the data has been most keyed in on the growing weight emotional bettors often put on Milwaukee’s strength factors between a Brewers team going up against a possibly unhealthy White Sox team. We’ve found the true game analytics appear to reflect a moderate lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI Milwaukee vs Chicago White Sox picks, computer picks Brewers vs White Sox, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
MLB 9/26 DET@BOS UNLOCK THIS PICK 5 EXECUTIVE Locked EXECUTIVE
MLB 9/26 BAL@NYY UNLOCK THIS PICK 4 INTEL Locked INTEL
MLB 9/26 ARI@SD UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
MLB 9/26 NYM@MIA UNLOCK THIS PICK 1 INTEL Locked INTEL
MLB 9/26 NYM@MIA GET FREE PICK NOW 1
MLB 9/26 COL@SF UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Brewers Betting Trends

The Brewers are 5–2 against the spread (ATS) in their last seven games, showcasing strong performance in covering the run line.

White Sox Betting Trends

The White Sox have struggled ATS, with a record of 7–21 overall, indicating challenges in covering the run line consistently.

Brewers vs. White Sox Matchup Trends

The Brewers are favored with a moneyline of -181, while the White Sox are underdogs at +150; the over/under is set at 8.5 runs.

Milwaukee vs. Chicago White Sox Game Info

Milwaukee vs Chicago White Sox starts on May 01, 2025 at 2:10 PM EST.

Spread: Chicago White Sox +1.5
Moneyline: Milwaukee -181, Chicago White Sox +150
Over/Under: 8.5

Milwaukee: (16-15)  |  Chicago White Sox: (7-23)

Remi's searched hard and found the best prop for this matchup: L. Robert over 0.5 Total Bases.. Prices move—always shop for the best number.

The Brewers are favored with a moneyline of -181, while the White Sox are underdogs at +150; the over/under is set at 8.5 runs.

MIL trend: The Brewers are 5–2 against the spread (ATS) in their last seven games, showcasing strong performance in covering the run line.

CHW trend: The White Sox have struggled ATS, with a record of 7–21 overall, indicating challenges in covering the run line consistently.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Milwaukee vs. Chicago White Sox Odds

Remi is pouring through mountains of stats on each team. In fact, anytime the Milwaukee vs Chicago White Sox trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme hostile environments seemingly never follow normal, predictable betting trends.

Milwaukee vs Chicago White Sox Opening Odds

MIL Moneyline: -181
CHW Moneyline: +150
MIL Spread: -1.5
CHW Spread: +1.5
Over/Under: 8.5

Milwaukee vs Chicago White Sox Live Odds

Games PTS ML SPR O/U
Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
Orioles
Yankees
+190
-235
+1.5 (-110)
-1.5 (-110)
O 8.5 (-120)
U 8.5 (+100)
Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
 
-175
 
-1.5 (+115)
O 9.5 (-105)
U 9.5 (-115)
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
+130
-155
+1.5 (-155)
-1.5 (+130)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:06PM
White Sox
Nationals
+100
-120
-1.5 (+165)
+1.5 (-200)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
+185
-225
+1.5 (-110)
-1.5 (-110)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
-130
+110
-1.5 (+125)
+1.5 (-150)
O 8.5 (-105)
U 8.5 (-115)
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
+170
-205
+1.5 (-120)
-1.5 (+100)
O 8.5 (-115)
U 8.5 (-105)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+125
-150
+1.5 (-180)
-1.5 (+150)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+140
-170
+1.5 (-155)
-1.5 (+130)
O 8 (-110)
U 8 (-110)
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
+135
-165
+1.5 (-180)
-1.5 (+150)
O 7 (-120)
U 7 (+100)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+115
-140
+1.5 (-190)
-1.5 (+155)
O 7.5 (-120)
U 7.5 (+100)
Sep 27, 2025 9:39PM EDT
Houston Astros
Los Angeles Angels
9/27/25 9:39PM
Astros
Angels
-165
+135
-1.5 (+105)
+1.5 (-125)
O 9 (+100)
U 9 (-120)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+100
-120
-1.5 (+170)
+1.5 (-205)
O 7.5 (-110)
U 7.5 (-110)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
+100
-120
-1.5 (+150)
+1.5 (-180)
O 10 (-110)
U 10 (-110)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Milwaukee Brewers vs. Chicago White Sox White Sox on May 01, 2025 at Rate Field.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS
CIN@ARI KEBRYAN HAYES STRIKEOUTS UNDER 0.5 56.2% 6 WIN
LAD@SD SD +110 50.9% 6 WIN