Cardinals vs Reds Prediction — AI Finds CAN'T MISS MLB Lines & Props (Apr 30)

Updated: 2025-04-28T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The St. Louis Cardinals and Cincinnati Reds are set to face off on April 30, 2025, at 6:40 PM ET at Great American Ball Park in Cincinnati. The Reds are favored at -142, with the Cardinals at +119, and the over/under set at 9 runs.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Apr 30, 2025

Start Time: 12:40 PM EST​

Venue: Great American Ball Park​

Reds Record: (16-13)

Cardinals Record: (12-17)

OPENING ODDS

STL Moneyline: +119

CIN Moneyline: -142

STL Spread: +1.5

CIN Spread: -1.5

Over/Under: 9

STL
Betting Trends

  • The Cardinals are 2-4 against the spread (ATS) in their last six games and have struggled on the road, going 1-7 straight up in their last eight away games.

CIN
Betting Trends

  • The Reds are 5-2 ATS in their last seven games and have covered the spread in 7 of their last 9 road games, indicating strong recent performance.

MATCHUP TRENDS

  • The total has gone UNDER in 10 of St. Louis’s last 15 games, suggesting a trend towards lower-scoring games involving the Cardinals.

STL vs. CIN
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: L. Nootbaar over 0.5 Total RBIs.

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St. Louis vs Cincinnati Prediction & Odds:
Free MLB Betting Insights for 4/30/25

The St. Louis Cardinals and Cincinnati Reds square off on April 30, 2025, in what sets up to be an important early-season divisional clash between two teams charting different trajectories. The Reds enter this matchup with a wave of momentum, having won key games both home and away, and are now looking to further establish their standing in the National League Central. Their recent stretch of play has featured sharp pitching, timely hitting, and improved defensive consistency, which has allowed them to climb the standings and gain confidence. On the mound, Cincinnati turns to Andrew Abbott, a left-hander who’s shown poise and command in his recent outings, particularly against teams that struggle with off-speed pitches. His ability to induce weak contact and limit walks has made him an effective presence, especially when backed by an improving bullpen. Opposing him is Steven Matz, a veteran southpaw for the Cardinals who has had an up-and-down season so far, occasionally struggling with command but still capable of stringing together quality starts when his mechanics are sound and his pitch sequencing is sharp. The key to this game may lie in how each lineup handles the left-handed pitching matchup. The Reds have been particularly effective at hitting lefties, with hitters like Elly De La Cruz and Spencer Steer showing impressive splits against southpaws.

Their ability to spark rallies at the top of the order and apply pressure through aggressive base running could give them a decided edge. Meanwhile, the Cardinals’ offense has been sluggish of late, especially on the road, where they’ve dropped seven of their last eight games and have found it difficult to string together quality at-bats in crucial situations. Lars Nootbaar and Paul Goldschmidt will need to step up and find a way to break through early against Abbott, as falling behind could lead to another frustrating night for a St. Louis club that has underwhelmed in recent weeks. Defensively, both teams will look to minimize errors and play clean baseball, but Cincinnati’s recent stretch suggests they’ve tightened up in the field, while St. Louis continues to deal with occasional lapses that extend innings and lead to big frames. From a betting perspective, the Reds are favored at home for good reason—they’ve been 5-2 ATS in their last seven and are generally playing a more confident, complete brand of baseball. With the total set at nine runs, oddsmakers expect some offensive action, but with two lefties on the mound and the Cardinals’ recent scoring woes, the under could come into play. In what could be a tone-setting game for the series, the Reds have the opportunity to press their advantage, while the Cardinals are desperate to reverse course and regain competitiveness within the division. This game, though not season-defining, carries enough weight to influence momentum, confidence, and managerial decisions moving forward, making it a must-watch for NL Central enthusiasts.

St. Louis Cardinals MLB Preview

The St. Louis Cardinals enter their April 30, 2025 matchup against the Cincinnati Reds amid a disappointing stretch of form, particularly on the road, where they’ve dropped seven of their last eight games and have appeared out of sync offensively and defensively. Their current 2-4 record against the spread in their last six games reflects deeper inconsistencies that have plagued this team since the early part of the season. Despite a roster featuring veterans and promising young talent, the Cardinals have struggled to piece together complete games, with their offense sputtering in high-leverage moments and their pitching staff faltering in late innings. The burden falls on Steven Matz to stabilize the rotation and deliver a quality start, but the veteran left-hander has been inconsistent, prone to giving up early runs when he fails to command his fastball or get ahead in counts. Matz’s success will largely depend on whether he can effectively mix in his off-speed pitches and neutralize a Cincinnati lineup that has been aggressive and efficient against left-handed pitching this season. Offensively, the Cardinals need a spark from key hitters like Paul Goldschmidt, who remains the centerpiece of their lineup but has lacked consistent support from the rest of the order. Lars Nootbaar, who offers speed and defensive versatility, has shown flashes of being a difference-maker, yet he, too, has struggled with consistency at the plate.

The Cardinals’ inability to manufacture runs through situational hitting—sacrifices, steals, and opposite-field contact—has limited their scoring opportunities and exposed the team’s overreliance on the long ball. With a struggling bullpen that has surrendered leads in recent games, the Cardinals find themselves in a position where they must play with greater urgency and discipline. Defensive lapses have compounded their issues, turning manageable innings into extended ones, and placing extra strain on their already taxed pitching staff. For St. Louis to turn the tide against the Reds, they’ll need to execute cleanly in all phases: Matz must limit hard contact early, the offense must capitalize on runners in scoring position, and the defense must support the pitching staff with crisp, mistake-free play. A return to fundamental baseball—shortening swings, executing cutoffs, and aggressive base running—could help reestablish the team’s rhythm. Managerial decisions will also be critical; Oli Marmol may need to be quicker to pull a struggling pitcher or get creative with pinch-hitting if the Cardinals fall behind early. While this game won’t determine their season, it offers an opportunity to stop the bleeding and reclaim momentum in a division that’s still very much open. If the Cardinals hope to be taken seriously as contenders this year, they’ll need to use this game as a catalyst for change, one where they respond with resolve, energy, and execution against a divisional foe that has had their number recently. A win in Cincinnati could serve as a much-needed confidence boost, while another loss could deepen the team’s early-season slide and raise questions about their readiness to compete.

The St. Louis Cardinals and Cincinnati Reds are set to face off on April 30, 2025, at 6:40 PM ET at Great American Ball Park in Cincinnati. The Reds are favored at -142, with the Cardinals at +119, and the over/under set at 9 runs. St. Louis vs Cincinnati AI Prediction: Free MLB Betting Insights for Apr 30. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Cincinnati Reds MLB Preview

The Cincinnati Reds return to Great American Ball Park on April 30, 2025, brimming with confidence as they prepare to face the struggling St. Louis Cardinals in the third game of a divisional set. Riding the momentum of a strong stretch that has seen them go 5-2 against the spread in their last seven games, the Reds have carved out a reputation as one of the more exciting and tenacious young teams in the National League. Their combination of speed, power, and emerging pitching talent has energized the fanbase and given manager David Bell a variety of options to work with each night. On the mound for this matchup is Andrew Abbott, the talented left-hander who has begun to find his stride after an uneven start to the year. Abbott’s improved command and increased reliance on his changeup and slider have made him more effective against right-handed hitters, which will be critical against a Cardinals lineup anchored by righties like Paul Goldschmidt and Nolan Arenado. Abbott’s ability to keep hitters off balance early and generate soft contact has been a key to his recent success, and the Reds will hope he can deliver another quality start against a team that’s struggled to generate offense on the road. Offensively, the Reds have been fueled by the electric play of Elly De La Cruz, whose ability to impact the game in multiple ways—power, speed, and defensive range—has made him a foundational piece of Cincinnati’s youth movement. His presence atop the order sets the tone, and when he gets on base, the Reds’ chances of scoring spike dramatically thanks to his aggressive base running and knack for creating havoc.

Alongside him, Spencer Steer, Matt McLain, and Jake Fraley have provided timely hitting and clutch performances, giving the Reds a balanced and productive offense. Even more encouraging is their ability to string together innings with patience and situational awareness, rather than relying solely on home runs to generate scoring. Against a Cardinals team that’s been prone to defensive lapses and bullpen collapses, the Reds will look to keep pressure on by working deep counts and forcing mistakes. Their discipline at the plate and aggression on the basepaths have become hallmarks of this team’s identity and will again be emphasized as they look to build a lead early. Defensively, the Reds have shown marked improvement, turning double plays cleanly, executing relays with precision, and limiting second-chance opportunities for opponents. That tightening of defensive fundamentals has been especially helpful in games where the pitching staff faces early jams, allowing the team to stay composed and weather storms without letting innings spiral out of control. The bullpen, once a major question mark, has stabilized in recent weeks, with Alexis Díaz continuing to lock down the ninth inning and middle relievers like Lucas Sims and Fernando Cruz stepping up in high-leverage situations. For the Reds, this game represents a prime opportunity to capitalize on a divisional rival’s recent slide and continue building their case as serious contenders in the NL Central. With home-field advantage, a strong starter on the mound, and a hungry lineup that feeds off energy and opportunity, Cincinnati has all the pieces in place to secure a win and keep their momentum rolling. A victory here would not only extend their lead over the Cardinals but also reinforce the notion that the Reds are no longer a team of the future—they’re a legitimate force in the present.

St. Louis vs. Cincinnati Prop Picks (AI)

AI algorithm Remi is pouring through tons of datapoints on each player. In fact, anytime the Cardinals and Reds play there’s always several intriguing angles to key in on. Not to mention games played at Great American Ball Park in Apr seemingly never follow normal, predictable patterns.
Remi's searched hard and found the best prop for this matchup: L. Nootbaar over 0.5 Total RBIs.

St. Louis vs. Cincinnati Prediction (AI)

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Remi, our AI sports genius, has been pouring over tons of data from every angle between the Cardinals and Reds and using recursive machine learning and impressive AI to boil down the data to a single cover probability.

Oddly enough, we’ve seen the AI has been most fixated on the growing factor human bettors regularly put on St. Louis’s strength factors between a Cardinals team going up against a possibly improved Reds team. Trends look to say the true game analytics appear to reflect a slight lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI St. Louis vs Cincinnati picks, computer picks Cardinals vs Reds, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
MLB 10/19 SEA@TOR UNLOCK THIS PICK 1 INTEL Locked INTEL
MLB 10/19 SEA@TOR UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Cardinals Betting Trends

The Cardinals are 2-4 against the spread (ATS) in their last six games and have struggled on the road, going 1-7 straight up in their last eight away games.

Reds Betting Trends

The Reds are 5-2 ATS in their last seven games and have covered the spread in 7 of their last 9 road games, indicating strong recent performance.

Cardinals vs. Reds Matchup Trends

The total has gone UNDER in 10 of St. Louis’s last 15 games, suggesting a trend towards lower-scoring games involving the Cardinals.

St. Louis vs. Cincinnati Game Info

St. Louis vs Cincinnati starts on April 30, 2025 at 12:40 PM EST.

Venue: Great American Ball Park.

Spread: Cincinnati -1.5
Moneyline: St. Louis +119, Cincinnati -142
Over/Under: 9

St. Louis: (12-17)  |  Cincinnati: (16-13)

Remi's searched hard and found the best prop for this matchup: L. Nootbaar over 0.5 Total RBIs.. Prices move—always shop for the best number.

The total has gone UNDER in 10 of St. Louis’s last 15 games, suggesting a trend towards lower-scoring games involving the Cardinals.

STL trend: The Cardinals are 2-4 against the spread (ATS) in their last six games and have struggled on the road, going 1-7 straight up in their last eight away games.

CIN trend: The Reds are 5-2 ATS in their last seven games and have covered the spread in 7 of their last 9 road games, indicating strong recent performance.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

St. Louis vs. Cincinnati Odds

Remi is pouring through mountains of stats on each team. In fact, anytime the St. Louis vs Cincinnati trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme temps rarely follow normal, predictable betting trends.

St. Louis vs Cincinnati Opening Odds

STL Moneyline: +119
CIN Moneyline: -142
STL Spread: +1.5
CIN Spread: -1.5
Over/Under: 9

St. Louis vs Cincinnati Live Odds

Games PTS ML SPR O/U
Oct 19, 2025 8:04PM EDT
Seattle Mariners
Toronto Blue Jays
10/19/25 8:04PM
Mariners
Blue Jays
+105
-125
+1.5 (-200)
-1.5 (+165)
O 7.5 (-120)
U 7.5 (+100)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers St. Louis Cardinals vs. Cincinnati Reds on April 30, 2025 at Great American Ball Park.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
TOR@SEA OVER 7 54.9% 3 WIN
LAD@MIL UNDER 7.5 56.6% 6 WIN
TOR@NYY OVER 8 54.9% 4 WIN
TOR@NYY CARLOS RODON OVER 1.5 TOTAL WALKS ALLOWED 53.3% 3 WIN
NYY@TOR OVER 7.5 54.8% 2 WIN
LAD@PHI OVER 7 53.8% 3 WIN
SD@CHC CHC -109 53.8% 3 WIN
SD@CHC OVER 7.5 54.5% 4 LOSS
SD@CHC CHC -111 54.8% 4 LOSS
CIN@LAD SHOHEI OHTANI OVER 1.5 BASES 53.5% 3 WIN
BOS@NYY OVER 7 53.8% 3 LOSS
CIN@LAD ELLY DE LA CRUZ OVER 0.5 BASES 54.4% 4 LOSS
ARI@SD SD -131 57.3% 4 WIN
DET@BOS BOS -115 56.4% 5 WIN
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN