Cardinals vs Reds Prediction — AI Finds CAN'T MISS MLB Lines & Props (Apr 30)
Updated: 2025-04-28T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The St. Louis Cardinals and Cincinnati Reds are set to face off on April 30, 2025, at 6:40 PM ET at Great American Ball Park in Cincinnati. The Reds are favored at -142, with the Cardinals at +119, and the over/under set at 9 runs.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Apr 30, 2025
Start Time: 12:40 PM EST
Venue: Great American Ball Park
Reds Record: (16-13)
Cardinals Record: (12-17)
OPENING ODDS
STL Moneyline: +119
CIN Moneyline: -142
STL Spread: +1.5
CIN Spread: -1.5
Over/Under: 9
STL
Betting Trends
- The Cardinals are 2-4 against the spread (ATS) in their last six games and have struggled on the road, going 1-7 straight up in their last eight away games.
CIN
Betting Trends
- The Reds are 5-2 ATS in their last seven games and have covered the spread in 7 of their last 9 road games, indicating strong recent performance.
MATCHUP TRENDS
- The total has gone UNDER in 10 of St. Louis’s last 15 games, suggesting a trend towards lower-scoring games involving the Cardinals.
STL vs. CIN
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: L. Nootbaar over 0.5 Total RBIs.
LIVE MLB ODDS
MLB ODDS COMPARISON
WANT MORE AI PICKS?
VS. SPREAD
323-240
NET UNITS
(INCL VIG)
+384.5
NET PROFIT
(INCL VIG)
$100/UNIT
$38,448
VS. SPREAD
1593-1364
NET UNITS
(INCL VIG)
+371.9
NET PROFIT
(INCL VIG)
$100/UNIT
$37,192
AI SPORTS PICK PRODUCTS
Create a Free Account

Remi Finds New Picks

Remi Works 24/7
Remi uses this probability to assign units to each pick.
Get Remi's AI Picks
Get Remi’s Top AI Sports Picks sent direct to your inbox.
Hedge Meaning in Betting | 4 Obvious Times to Hedge
Learn about hedge betting to manage risk and secure profits. Understand...
What is a Push in Betting? | 3 Ways To Use To Your Advantage
Understand what a push in betting means, how it happens in...
What Does the + and – Mean in Sports Betting? | 5 Easy Tips
Learn the basics of sports betting odds, what the plus (+)...
St. Louis vs Cincinnati Prediction & Odds:
Free MLB Betting Insights for 4/30/25
Their ability to spark rallies at the top of the order and apply pressure through aggressive base running could give them a decided edge. Meanwhile, the Cardinals’ offense has been sluggish of late, especially on the road, where they’ve dropped seven of their last eight games and have found it difficult to string together quality at-bats in crucial situations. Lars Nootbaar and Paul Goldschmidt will need to step up and find a way to break through early against Abbott, as falling behind could lead to another frustrating night for a St. Louis club that has underwhelmed in recent weeks. Defensively, both teams will look to minimize errors and play clean baseball, but Cincinnati’s recent stretch suggests they’ve tightened up in the field, while St. Louis continues to deal with occasional lapses that extend innings and lead to big frames. From a betting perspective, the Reds are favored at home for good reason—they’ve been 5-2 ATS in their last seven and are generally playing a more confident, complete brand of baseball. With the total set at nine runs, oddsmakers expect some offensive action, but with two lefties on the mound and the Cardinals’ recent scoring woes, the under could come into play. In what could be a tone-setting game for the series, the Reds have the opportunity to press their advantage, while the Cardinals are desperate to reverse course and regain competitiveness within the division. This game, though not season-defining, carries enough weight to influence momentum, confidence, and managerial decisions moving forward, making it a must-watch for NL Central enthusiasts.
Game 2 in Cincy pic.twitter.com/v2jrAr7Kto
— St. Louis Cardinals (@Cardinals) April 29, 2025
St. Louis Cardinals MLB Preview
The St. Louis Cardinals enter their April 30, 2025 matchup against the Cincinnati Reds amid a disappointing stretch of form, particularly on the road, where they’ve dropped seven of their last eight games and have appeared out of sync offensively and defensively. Their current 2-4 record against the spread in their last six games reflects deeper inconsistencies that have plagued this team since the early part of the season. Despite a roster featuring veterans and promising young talent, the Cardinals have struggled to piece together complete games, with their offense sputtering in high-leverage moments and their pitching staff faltering in late innings. The burden falls on Steven Matz to stabilize the rotation and deliver a quality start, but the veteran left-hander has been inconsistent, prone to giving up early runs when he fails to command his fastball or get ahead in counts. Matz’s success will largely depend on whether he can effectively mix in his off-speed pitches and neutralize a Cincinnati lineup that has been aggressive and efficient against left-handed pitching this season. Offensively, the Cardinals need a spark from key hitters like Paul Goldschmidt, who remains the centerpiece of their lineup but has lacked consistent support from the rest of the order. Lars Nootbaar, who offers speed and defensive versatility, has shown flashes of being a difference-maker, yet he, too, has struggled with consistency at the plate.
The Cardinals’ inability to manufacture runs through situational hitting—sacrifices, steals, and opposite-field contact—has limited their scoring opportunities and exposed the team’s overreliance on the long ball. With a struggling bullpen that has surrendered leads in recent games, the Cardinals find themselves in a position where they must play with greater urgency and discipline. Defensive lapses have compounded their issues, turning manageable innings into extended ones, and placing extra strain on their already taxed pitching staff. For St. Louis to turn the tide against the Reds, they’ll need to execute cleanly in all phases: Matz must limit hard contact early, the offense must capitalize on runners in scoring position, and the defense must support the pitching staff with crisp, mistake-free play. A return to fundamental baseball—shortening swings, executing cutoffs, and aggressive base running—could help reestablish the team’s rhythm. Managerial decisions will also be critical; Oli Marmol may need to be quicker to pull a struggling pitcher or get creative with pinch-hitting if the Cardinals fall behind early. While this game won’t determine their season, it offers an opportunity to stop the bleeding and reclaim momentum in a division that’s still very much open. If the Cardinals hope to be taken seriously as contenders this year, they’ll need to use this game as a catalyst for change, one where they respond with resolve, energy, and execution against a divisional foe that has had their number recently. A win in Cincinnati could serve as a much-needed confidence boost, while another loss could deepen the team’s early-season slide and raise questions about their readiness to compete.

Credit: USA TODAY/IMAGN
Cincinnati Reds MLB Preview
The Cincinnati Reds return to Great American Ball Park on April 30, 2025, brimming with confidence as they prepare to face the struggling St. Louis Cardinals in the third game of a divisional set. Riding the momentum of a strong stretch that has seen them go 5-2 against the spread in their last seven games, the Reds have carved out a reputation as one of the more exciting and tenacious young teams in the National League. Their combination of speed, power, and emerging pitching talent has energized the fanbase and given manager David Bell a variety of options to work with each night. On the mound for this matchup is Andrew Abbott, the talented left-hander who has begun to find his stride after an uneven start to the year. Abbott’s improved command and increased reliance on his changeup and slider have made him more effective against right-handed hitters, which will be critical against a Cardinals lineup anchored by righties like Paul Goldschmidt and Nolan Arenado. Abbott’s ability to keep hitters off balance early and generate soft contact has been a key to his recent success, and the Reds will hope he can deliver another quality start against a team that’s struggled to generate offense on the road. Offensively, the Reds have been fueled by the electric play of Elly De La Cruz, whose ability to impact the game in multiple ways—power, speed, and defensive range—has made him a foundational piece of Cincinnati’s youth movement. His presence atop the order sets the tone, and when he gets on base, the Reds’ chances of scoring spike dramatically thanks to his aggressive base running and knack for creating havoc.
Alongside him, Spencer Steer, Matt McLain, and Jake Fraley have provided timely hitting and clutch performances, giving the Reds a balanced and productive offense. Even more encouraging is their ability to string together innings with patience and situational awareness, rather than relying solely on home runs to generate scoring. Against a Cardinals team that’s been prone to defensive lapses and bullpen collapses, the Reds will look to keep pressure on by working deep counts and forcing mistakes. Their discipline at the plate and aggression on the basepaths have become hallmarks of this team’s identity and will again be emphasized as they look to build a lead early. Defensively, the Reds have shown marked improvement, turning double plays cleanly, executing relays with precision, and limiting second-chance opportunities for opponents. That tightening of defensive fundamentals has been especially helpful in games where the pitching staff faces early jams, allowing the team to stay composed and weather storms without letting innings spiral out of control. The bullpen, once a major question mark, has stabilized in recent weeks, with Alexis Díaz continuing to lock down the ninth inning and middle relievers like Lucas Sims and Fernando Cruz stepping up in high-leverage situations. For the Reds, this game represents a prime opportunity to capitalize on a divisional rival’s recent slide and continue building their case as serious contenders in the NL Central. With home-field advantage, a strong starter on the mound, and a hungry lineup that feeds off energy and opportunity, Cincinnati has all the pieces in place to secure a win and keep their momentum rolling. A victory here would not only extend their lead over the Cardinals but also reinforce the notion that the Reds are no longer a team of the future—they’re a legitimate force in the present.
Hitmakers pic.twitter.com/azJzMLLhVD
— Cincinnati Reds (@Reds) April 29, 2025
St. Louis vs. Cincinnati Prop Picks (AI)
St. Louis vs. Cincinnati Prediction (AI)

Remi, our AI sports genius, has been pouring over tons of data from every angle between the Cardinals and Reds and using recursive machine learning and impressive AI to boil down the data to a single cover probability.
Oddly enough, we’ve seen the AI has been most fixated on the growing factor human bettors regularly put on St. Louis’s strength factors between a Cardinals team going up against a possibly improved Reds team. Trends look to say the true game analytics appear to reflect a slight lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.
Below is our current AI St. Louis vs Cincinnati picks, computer picks Cardinals vs Reds, best bets, model edges, confidence ratings.
![]() |
DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
---|---|---|---|---|---|---|
MLB | 10/19 | SEA@TOR | UNLOCK THIS PICK | 1 |
![]() |
|
MLB | 10/19 | SEA@TOR | UNLOCK THIS PICK | 0 |
![]() |
These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.
Cardinals Betting Trends
The Cardinals are 2-4 against the spread (ATS) in their last six games and have struggled on the road, going 1-7 straight up in their last eight away games.
Reds Betting Trends
The Reds are 5-2 ATS in their last seven games and have covered the spread in 7 of their last 9 road games, indicating strong recent performance.
Cardinals vs. Reds Matchup Trends
The total has gone UNDER in 10 of St. Louis’s last 15 games, suggesting a trend towards lower-scoring games involving the Cardinals.
St. Louis vs. Cincinnati Game Info
What time does St. Louis vs Cincinnati start on April 30, 2025?
St. Louis vs Cincinnati starts on April 30, 2025 at 12:40 PM EST.
Where is St. Louis vs Cincinnati being played?
Venue: Great American Ball Park.
What are the opening odds for St. Louis vs Cincinnati?
Spread: Cincinnati -1.5
Moneyline: St. Louis +119, Cincinnati -142
Over/Under: 9
What are the records for St. Louis vs Cincinnati?
St. Louis: (12-17) | Cincinnati: (16-13)
What is the AI best bet for St. Louis vs Cincinnati?
Remi's searched hard and found the best prop for this matchup: L. Nootbaar over 0.5 Total RBIs.. Prices move—always shop for the best number.
What are St. Louis vs Cincinnati trending bets?
The total has gone UNDER in 10 of St. Louis’s last 15 games, suggesting a trend towards lower-scoring games involving the Cardinals.
What are St. Louis trending bets?
STL trend: The Cardinals are 2-4 against the spread (ATS) in their last six games and have struggled on the road, going 1-7 straight up in their last eight away games.
What are Cincinnati trending bets?
CIN trend: The Reds are 5-2 ATS in their last seven games and have covered the spread in 7 of their last 9 road games, indicating strong recent performance.
Where can I find AI Picks for St. Louis vs Cincinnati?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
St. Louis vs. Cincinnati Odds
Remi is pouring through mountains of stats on each team. In fact, anytime the St. Louis vs Cincinnati trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme temps rarely follow normal, predictable betting trends.
St. Louis vs Cincinnati Opening Odds
STL Moneyline:
+119 CIN Moneyline: -142
STL Spread: +1.5
CIN Spread: -1.5
Over/Under: 9
St. Louis vs Cincinnati Live Odds
Games | PTS | ML | SPR | O/U | |
---|---|---|---|---|---|
Oct 19, 2025 8:04PM EDT
Seattle Mariners
Toronto Blue Jays
10/19/25 8:04PM
Mariners
Blue Jays
|
–
–
|
+105
-125
|
+1.5 (-200)
-1.5 (+165)
|
O 7.5 (-120)
U 7.5 (+100)
|
MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers St. Louis Cardinals vs. Cincinnati Reds on April 30, 2025 at Great American Ball Park.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
![]() |
LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
TOR@SEA | OVER 7 | 54.9% | 3 | WIN |
LAD@MIL | UNDER 7.5 | 56.6% | 6 | WIN |
TOR@NYY | OVER 8 | 54.9% | 4 | WIN |
TOR@NYY | CARLOS RODON OVER 1.5 TOTAL WALKS ALLOWED | 53.3% | 3 | WIN |
NYY@TOR | OVER 7.5 | 54.8% | 2 | WIN |
LAD@PHI | OVER 7 | 53.8% | 3 | WIN |
SD@CHC | CHC -109 | 53.8% | 3 | WIN |
SD@CHC | OVER 7.5 | 54.5% | 4 | LOSS |
SD@CHC | CHC -111 | 54.8% | 4 | LOSS |
CIN@LAD | SHOHEI OHTANI OVER 1.5 BASES | 53.5% | 3 | WIN |
BOS@NYY | OVER 7 | 53.8% | 3 | LOSS |
CIN@LAD | ELLY DE LA CRUZ OVER 0.5 BASES | 54.4% | 4 | LOSS |
ARI@SD | SD -131 | 57.3% | 4 | WIN |
DET@BOS | BOS -115 | 56.4% | 5 | WIN |
NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
LAA@COL | COL +108 | 50.5% | 3 | WIN |
TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
KC@PHI | PHI -130 | 58.3% | 4 | WIN |
LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
KC@CLE | KC -104 | 52.0% | 3 | WIN |
CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |