Reds vs. Rockies
Prediction, Odds & Props
Apr 26 | MLB AI Picks
Updated: 2025-04-24T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Cincinnati Reds (12–13) face the Colorado Rockies (4–20) on Saturday, April 26, 2025, at Coors Field in Denver, with first pitch scheduled for 3:10 p.m. EDT. The Reds aim to improve their standing in the NL Central, while the Rockies seek to snap a four-game losing streak.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Apr 26, 2025
Start Time: 3:10 PM EST
Venue: Coors Field
Rockies Record: (4-21)
Reds Record: (13-13)
OPENING ODDS
CIN Moneyline: -192
COL Moneyline: +160
CIN Spread: -1.5
COL Spread: +1.5
Over/Under: 10.5
CIN
Betting Trends
- The Reds have been solid against the spread (ATS) on the road, posting a 7–4 record in their last 11 away games. Their consistent performance has made them a reliable pick for bettors in recent matchups.
COL
Betting Trends
- The Rockies have struggled ATS at home, with a 4–11 record in their last 15 home games. Their inconsistent play has made it challenging for bettors to back them confidently.
MATCHUP TRENDS
- In head-to-head matchups, the Reds have covered the spread in four of their last six games against the Rockies. Additionally, the total runs have gone over in five of the last seven meetings between these two teams, indicating a trend toward high-scoring affairs.
CIN vs. COL
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: E. De La Cruz over 8.5 Fantasy Score.
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Cincinnati vs Colorado Prediction & Odds:
Free MLB Betting Insights for 4/26/25
Defensively, Cincinnati has shown improvement this season, cutting down on errors and playing a cleaner brand of baseball that has helped them stay competitive in close games, while Colorado’s defense has been spotty at best, contributing to their prolonged struggles. Bullpen reliability has favored the Reds as well, with a more structured late-inning plan compared to the Rockies’ patchwork relief corps that has too often turned deficits into blowouts. Recent betting trends favor the Reds, who have covered the spread in four of their last six meetings with the Rockies and have performed well on the road overall, while games between these teams have frequently trended toward the over, thanks in large part to Coors Field’s reputation for turning even average offenses into juggernauts. For Cincinnati, the blueprint is clear: get an early lead, let Greene attack the Rockies’ struggling lineup, and avoid defensive miscues that could allow Colorado back into the game. For the Rockies, success hinges on somehow containing the Reds’ offense early, giving Senzatela a lead to work with, and hoping the thin air of Denver can help jumpstart their own moribund bats. With both teams feeling the urgency—Cincinnati to get to .500 and Colorado simply to stop a disastrous slide—Saturday’s game should feature an aggressive approach on both sides, but if Greene pitches to his potential and the Reds’ offense capitalizes on their chances, Cincinnati will have a golden opportunity to walk away with another road victory and keep their season trending in the right direction.
Another perfect outing for Emilio
— Cincinnati Reds (@Reds) April 26, 2025
🔒🔒🔒🔒🔒🔒 pic.twitter.com/26vYHlPnLG
Cincinnati Reds MLB Preview
The Cincinnati Reds head into Saturday’s matchup against the Colorado Rockies at Coors Field with a renewed sense of optimism, looking to climb back to a .500 record and continue their promising start to the 2025 season after showing resilience through early challenges. At 12–13, the Reds find themselves firmly in the mix in the National League Central and have leaned heavily on the dynamic talents of Elly De La Cruz, whose electric play at the plate, on the bases, and in the field has made him one of the game’s rising stars. Jonathan India’s leadership and consistent on-base presence have helped solidify the top of the lineup, providing opportunities for De La Cruz, Spencer Steer, and Christian Encarnacion-Strand to drive in runs and fuel an offense that has the potential to explode, especially in the hitter-friendly confines of Coors Field. On the mound, Hunter Greene takes the ball carrying a 2–2 record and an impressive 2.35 ERA, a testament to his growing maturity and improved command that have made him one of the most difficult pitchers in the league to square up when he’s on.
Greene’s ability to mix a blistering fastball with an improving slider will be critical in navigating the thin Denver air that can turn even weak contact into extra-base hits. Cincinnati’s defense has been another area of growth, with fewer errors compared to previous seasons, and the team’s improved fundamentals have helped turn close games in their favor. Bullpen depth has been tested but generally reliable, and manager David Bell has shown a willingness to manage aggressively, using his best relievers in high-leverage spots regardless of traditional roles. The key for the Reds in this matchup will be to strike early, capitalize on scoring opportunities against Antonio Senzatela, and avoid defensive miscues that can quickly snowball at Coors Field. If Greene can establish command early and keep Colorado’s hitters off balance, Cincinnati has the firepower to outslug the Rockies and secure a crucial road win. Every game counts in the tightly packed NL Central, and stacking victories now would pay huge dividends later in the summer; Saturday’s contest offers the Reds a prime opportunity to assert themselves and continue their climb toward contention.

Credit: USA TODAY/IMAGN
Colorado Rockies MLB Preview
The Colorado Rockies return to Coors Field for Saturday’s matchup against the Cincinnati Reds desperately seeking a spark to end their brutal early-season slide, having stumbled to a 4–20 record that has left them with the worst mark in Major League Baseball through the first month of 2025. Manager Bud Black faces mounting challenges trying to keep his clubhouse motivated amid mounting losses and a schedule that has shown little mercy, and Saturday’s game offers a critical opportunity to begin changing the narrative. Veteran right-hander Antonio Senzatela gets the start and carries the weight of stabilizing a pitching staff that has struggled mightily both at home and on the road; while Senzatela’s 4.81 ERA is relatively solid by Coors Field standards, his inability to work deep into games has placed additional strain on an already overworked bullpen. Offensively, the Rockies continue to rely heavily on Ryan McMahon and Brendan Rodgers to generate scoring opportunities, but the lack of consistent production from the bottom half of the order has rendered their rallies sporadic at best. Coors Field’s hitter-friendly conditions remain an asset, but Colorado’s inability to capitalize with runners in scoring position has neutralized their traditional home-field advantage.
Defensively, the Rockies have been error-prone, and mental lapses in the field have consistently extended innings, allowing opposing teams to blow open close contests and bury Colorado early. For the Rockies to have a chance against a young, energetic Reds squad, they must play a clean defensive game, get a quality start from Senzatela that keeps the ball in the yard, and find ways to string together hits instead of relying solely on solo home runs. The bullpen must also be sharper in holding small leads or keeping games within reach, as blowing multi-run leads has been a recurring theme that has crushed morale. A win would not erase the tough start but could serve as an emotional lift for a club badly in need of positive momentum, and with the Reds sending out a hard-throwing but still-maturing starter in Hunter Greene, the Rockies have an opportunity if they can be patient, work deep counts, and exploit any command issues. The task is tall, but it is not impossible if Colorado can rediscover some of the offensive firepower that once made Coors Field a nightmare for visiting pitchers.
The Mike Honcho Taco's Special pic.twitter.com/yoWz8TTn7N
— Colorado Rockies (@Rockies) April 26, 2025
Cincinnati vs. Colorado Prop Picks (AI)
Cincinnati vs. Colorado Prediction (AI)

Remi, our AI sports wizard, has been pouring over exorbitant amounts of data from every facet between the Reds and Rockies and using recursive machine learning and kick-ass AI to crunch the data to a single cover probability.
Interestingly enough, the data has been most focused on the growing weight knucklehead sportsbettors regularly put on coaching factors between a Reds team going up against a possibly strong Rockies team. It appears the true game analytics might reflect a strong lean against one Vegas line specifically.
Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.
Below is our current AI Cincinnati vs Colorado picks, computer picks Reds vs Rockies, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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MLB | 9/26 | DET@BOS | UNLOCK THIS PICK | 5 |
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MLB | 9/26 | BAL@NYY | UNLOCK THIS PICK | 4 |
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MLB | 9/26 | ARI@SD | UNLOCK THIS PICK | 4 |
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MLB | 9/26 | NYM@MIA | UNLOCK THIS PICK | 1 |
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MLB | 9/26 | NYM@MIA | GET FREE PICK NOW | 1 | – | |
MLB | 9/26 | COL@SF | UNLOCK THIS PICK | 0 |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.
Reds Betting Trends
The Reds have been solid against the spread (ATS) on the road, posting a 7–4 record in their last 11 away games. Their consistent performance has made them a reliable pick for bettors in recent matchups.
Rockies Betting Trends
The Rockies have struggled ATS at home, with a 4–11 record in their last 15 home games. Their inconsistent play has made it challenging for bettors to back them confidently.
Reds vs. Rockies Matchup Trends
In head-to-head matchups, the Reds have covered the spread in four of their last six games against the Rockies. Additionally, the total runs have gone over in five of the last seven meetings between these two teams, indicating a trend toward high-scoring affairs.
Cincinnati vs. Colorado Game Info
What time does Cincinnati vs Colorado start on April 26, 2025?
Cincinnati vs Colorado starts on April 26, 2025 at 3:10 PM EST.
Where is Cincinnati vs Colorado being played?
Venue: Coors Field.
What are the opening odds for Cincinnati vs Colorado?
Spread: Colorado +1.5
Moneyline: Cincinnati -192, Colorado +160
Over/Under: 10.5
What are the records for Cincinnati vs Colorado?
Cincinnati: (13-13) | Colorado: (4-21)
What is the AI best bet for Cincinnati vs Colorado?
Remi's searched hard and found the best prop for this matchup: E. De La Cruz over 8.5 Fantasy Score.. Prices move—always shop for the best number.
What are Cincinnati vs Colorado trending bets?
In head-to-head matchups, the Reds have covered the spread in four of their last six games against the Rockies. Additionally, the total runs have gone over in five of the last seven meetings between these two teams, indicating a trend toward high-scoring affairs.
What are Cincinnati trending bets?
CIN trend: The Reds have been solid against the spread (ATS) on the road, posting a 7–4 record in their last 11 away games. Their consistent performance has made them a reliable pick for bettors in recent matchups.
What are Colorado trending bets?
COL trend: The Rockies have struggled ATS at home, with a 4–11 record in their last 15 home games. Their inconsistent play has made it challenging for bettors to back them confidently.
Where can I find AI Picks for Cincinnati vs Colorado?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
Cincinnati vs. Colorado Odds
AI algorithm Remi is pouring through loads of stats on each line. In fact, anytime the Cincinnati vs Colorado trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme travel distance almost always follow normal, predictable betting trends.
Cincinnati vs Colorado Opening Odds
CIN Moneyline:
-192 COL Moneyline: +160
CIN Spread: -1.5
COL Spread: +1.5
Over/Under: 10.5
Cincinnati vs Colorado Live Odds
Games | PTS | ML | SPR | O/U | |
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Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
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Yankees
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–
–
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+190
-235
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+1.5 (-110)
-1.5 (-110)
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O 8.5 (-120)
U 8.5 (+100)
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Sep 27, 2025 2:21PM EDT
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Chicago Cubs
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–
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-175
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-1.5 (+115)
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O 9.5 (-105)
U 9.5 (-115)
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Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
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–
–
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+130
-155
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+1.5 (-155)
-1.5 (+130)
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O 8.5 (-110)
U 8.5 (-110)
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Sep 27, 2025 4:06PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:06PM
White Sox
Nationals
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–
–
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+100
-120
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-1.5 (+165)
+1.5 (-200)
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O 8.5 (-110)
U 8.5 (-110)
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Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
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–
–
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+185
-225
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+1.5 (-110)
-1.5 (-110)
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O 8 (-105)
U 8 (-115)
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Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
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–
–
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-130
+110
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-1.5 (+125)
+1.5 (-150)
|
O 8.5 (-105)
U 8.5 (-115)
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Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
|
–
–
|
+170
-205
|
+1.5 (-120)
-1.5 (+100)
|
O 8.5 (-115)
U 8.5 (-105)
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Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
|
–
–
|
+125
-150
|
+1.5 (-180)
-1.5 (+150)
|
O 8 (-105)
U 8 (-115)
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Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
|
–
–
|
+140
-170
|
+1.5 (-155)
-1.5 (+130)
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O 8 (-110)
U 8 (-110)
|
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Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
|
–
–
|
+135
-165
|
+1.5 (-180)
-1.5 (+150)
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O 7 (-120)
U 7 (+100)
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Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
|
–
–
|
+115
-140
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+1.5 (-190)
-1.5 (+155)
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O 7.5 (-120)
U 7.5 (+100)
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Sep 27, 2025 9:39PM EDT
Houston Astros
Los Angeles Angels
9/27/25 9:39PM
Astros
Angels
|
–
–
|
-165
+135
|
-1.5 (+105)
+1.5 (-125)
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O 9 (+100)
U 9 (-120)
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Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
|
–
–
|
+100
-120
|
-1.5 (+170)
+1.5 (-205)
|
O 7.5 (-110)
U 7.5 (-110)
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Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
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–
–
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+100
-120
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-1.5 (+150)
+1.5 (-180)
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O 10 (-110)
U 10 (-110)
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MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Cincinnati Reds vs. Colorado Rockies on April 26, 2025 at Coors Field.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
LAA@COL | COL +108 | 50.5% | 3 | WIN |
TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
KC@PHI | PHI -130 | 58.3% | 4 | WIN |
LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
KC@CLE | KC -104 | 52.0% | 3 | WIN |
CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |
PHI@NYM | OVER 8.5 | 55.6% | 4 | LOSS |
LAA@TEX | LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS | 54.1% | 4 | LOSS |
KC@CHW | KC -109 | 54.2% | 4 | WIN |
SD@SEA | DYLAN CEASE OVER 16.5 OUTS | 53.9% | 3 | LOSS |
SD@SEA | UNDER 8.5 | 54.4% | 4 | LOSS |
MIN@TOR | JOE RYAN UNDER 2.5 EARNED RUNS | 54.1% | 4 | LOSS |
SF@MIL | MIL +100 | 54.0% | 6 | LOSS |
TOR@MIA | MIA +1.5 | 62.0% | 6 | WIN |
CHC@LAA | OVER 9.5 | 54.9% | 4 | LOSS |
BOS@NYY | CARLOS RODON UNDER 4.5 HITS ALLOWED | 54.2% | 4 | WIN |
KC@DET | DET -115 | 56.1% | 5 | WIN |
CHC@LAA | LAA +1.5 | 57.6% | 5 | LOSS |
CIN@ARI | KEBRYAN HAYES STRIKEOUTS UNDER 0.5 | 56.2% | 6 | WIN |
LAD@SD | SD +110 | 50.9% | 6 | WIN |