Reds vs. Rockies
Prediction, Odds & Props
Apr 26 | MLB AI Picks

Updated: 2025-04-24T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Cincinnati Reds (12–13) face the Colorado Rockies (4–20) on Saturday, April 26, 2025, at Coors Field in Denver, with first pitch scheduled for 3:10 p.m. EDT. The Reds aim to improve their standing in the NL Central, while the Rockies seek to snap a four-game losing streak.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Apr 26, 2025

Start Time: 3:10 PM EST​

Venue: Coors Field​

Rockies Record: (4-21)

Reds Record: (13-13)

OPENING ODDS

CIN Moneyline: -192

COL Moneyline: +160

CIN Spread: -1.5

COL Spread: +1.5

Over/Under: 10.5

CIN
Betting Trends

  • The Reds have been solid against the spread (ATS) on the road, posting a 7–4 record in their last 11 away games. Their consistent performance has made them a reliable pick for bettors in recent matchups.

COL
Betting Trends

  • The Rockies have struggled ATS at home, with a 4–11 record in their last 15 home games. Their inconsistent play has made it challenging for bettors to back them confidently.

MATCHUP TRENDS

  • In head-to-head matchups, the Reds have covered the spread in four of their last six games against the Rockies. Additionally, the total runs have gone over in five of the last seven meetings between these two teams, indicating a trend toward high-scoring affairs.

CIN vs. COL
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: E. De La Cruz over 8.5 Fantasy Score.

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Cincinnati vs Colorado Prediction & Odds:
Free MLB Betting Insights for 4/26/25

The Cincinnati Reds and Colorado Rockies meet at Coors Field on April 26, 2025, in a game that finds both teams in very different places in terms of expectations and momentum, with the Reds looking to reach .500 and the Rockies desperate to stop the bleeding after a brutal start to the season. Cincinnati, currently sitting at 12–13, has shown flashes of promise behind strong starting pitching and an emerging offense, and they will send flame-throwing right-hander Hunter Greene to the mound, who carries a 2–2 record and an impressive 2.35 ERA while consistently overpowering hitters with his triple-digit fastball and improving secondary pitches. Meanwhile, the Rockies, languishing at 4–20, turn to veteran Antonio Senzatela, who has struggled with a 1–3 record and a 4.81 ERA, tasked with trying to stabilize a rotation that has been battered early and often, particularly at home where Coors Field’s altitude has made it difficult to contain opposing offenses. Offensively, the Reds are led by the electrifying Elly De La Cruz, whose speed, power, and flair have made him a rising star, and steady veteran Jonathan India, who provides critical table-setting ability and leadership at the top of the order. The Rockies, searching for any offensive spark, continue to lean on Ryan McMahon and Brendan Rodgers, but consistent run production has been a major issue, and without more help from the supporting cast, Colorado finds itself unable to keep pace in high-scoring games.

Defensively, Cincinnati has shown improvement this season, cutting down on errors and playing a cleaner brand of baseball that has helped them stay competitive in close games, while Colorado’s defense has been spotty at best, contributing to their prolonged struggles. Bullpen reliability has favored the Reds as well, with a more structured late-inning plan compared to the Rockies’ patchwork relief corps that has too often turned deficits into blowouts. Recent betting trends favor the Reds, who have covered the spread in four of their last six meetings with the Rockies and have performed well on the road overall, while games between these teams have frequently trended toward the over, thanks in large part to Coors Field’s reputation for turning even average offenses into juggernauts. For Cincinnati, the blueprint is clear: get an early lead, let Greene attack the Rockies’ struggling lineup, and avoid defensive miscues that could allow Colorado back into the game. For the Rockies, success hinges on somehow containing the Reds’ offense early, giving Senzatela a lead to work with, and hoping the thin air of Denver can help jumpstart their own moribund bats. With both teams feeling the urgency—Cincinnati to get to .500 and Colorado simply to stop a disastrous slide—Saturday’s game should feature an aggressive approach on both sides, but if Greene pitches to his potential and the Reds’ offense capitalizes on their chances, Cincinnati will have a golden opportunity to walk away with another road victory and keep their season trending in the right direction.

Cincinnati Reds MLB Preview

The Cincinnati Reds head into Saturday’s matchup against the Colorado Rockies at Coors Field with a renewed sense of optimism, looking to climb back to a .500 record and continue their promising start to the 2025 season after showing resilience through early challenges. At 12–13, the Reds find themselves firmly in the mix in the National League Central and have leaned heavily on the dynamic talents of Elly De La Cruz, whose electric play at the plate, on the bases, and in the field has made him one of the game’s rising stars. Jonathan India’s leadership and consistent on-base presence have helped solidify the top of the lineup, providing opportunities for De La Cruz, Spencer Steer, and Christian Encarnacion-Strand to drive in runs and fuel an offense that has the potential to explode, especially in the hitter-friendly confines of Coors Field. On the mound, Hunter Greene takes the ball carrying a 2–2 record and an impressive 2.35 ERA, a testament to his growing maturity and improved command that have made him one of the most difficult pitchers in the league to square up when he’s on.

Greene’s ability to mix a blistering fastball with an improving slider will be critical in navigating the thin Denver air that can turn even weak contact into extra-base hits. Cincinnati’s defense has been another area of growth, with fewer errors compared to previous seasons, and the team’s improved fundamentals have helped turn close games in their favor. Bullpen depth has been tested but generally reliable, and manager David Bell has shown a willingness to manage aggressively, using his best relievers in high-leverage spots regardless of traditional roles. The key for the Reds in this matchup will be to strike early, capitalize on scoring opportunities against Antonio Senzatela, and avoid defensive miscues that can quickly snowball at Coors Field. If Greene can establish command early and keep Colorado’s hitters off balance, Cincinnati has the firepower to outslug the Rockies and secure a crucial road win. Every game counts in the tightly packed NL Central, and stacking victories now would pay huge dividends later in the summer; Saturday’s contest offers the Reds a prime opportunity to assert themselves and continue their climb toward contention.

The Cincinnati Reds (12–13) face the Colorado Rockies (4–20) on Saturday, April 26, 2025, at Coors Field in Denver, with first pitch scheduled for 3:10 p.m. EDT. The Reds aim to improve their standing in the NL Central, while the Rockies seek to snap a four-game losing streak. Cincinnati vs Colorado AI Prediction: Free MLB Betting Insights for Apr 26. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Colorado Rockies MLB Preview

The Colorado Rockies return to Coors Field for Saturday’s matchup against the Cincinnati Reds desperately seeking a spark to end their brutal early-season slide, having stumbled to a 4–20 record that has left them with the worst mark in Major League Baseball through the first month of 2025. Manager Bud Black faces mounting challenges trying to keep his clubhouse motivated amid mounting losses and a schedule that has shown little mercy, and Saturday’s game offers a critical opportunity to begin changing the narrative. Veteran right-hander Antonio Senzatela gets the start and carries the weight of stabilizing a pitching staff that has struggled mightily both at home and on the road; while Senzatela’s 4.81 ERA is relatively solid by Coors Field standards, his inability to work deep into games has placed additional strain on an already overworked bullpen. Offensively, the Rockies continue to rely heavily on Ryan McMahon and Brendan Rodgers to generate scoring opportunities, but the lack of consistent production from the bottom half of the order has rendered their rallies sporadic at best. Coors Field’s hitter-friendly conditions remain an asset, but Colorado’s inability to capitalize with runners in scoring position has neutralized their traditional home-field advantage.

Defensively, the Rockies have been error-prone, and mental lapses in the field have consistently extended innings, allowing opposing teams to blow open close contests and bury Colorado early. For the Rockies to have a chance against a young, energetic Reds squad, they must play a clean defensive game, get a quality start from Senzatela that keeps the ball in the yard, and find ways to string together hits instead of relying solely on solo home runs. The bullpen must also be sharper in holding small leads or keeping games within reach, as blowing multi-run leads has been a recurring theme that has crushed morale. A win would not erase the tough start but could serve as an emotional lift for a club badly in need of positive momentum, and with the Reds sending out a hard-throwing but still-maturing starter in Hunter Greene, the Rockies have an opportunity if they can be patient, work deep counts, and exploit any command issues. The task is tall, but it is not impossible if Colorado can rediscover some of the offensive firepower that once made Coors Field a nightmare for visiting pitchers.

Cincinnati vs. Colorado Prop Picks (AI)

AI algorithm Remi is pouring through tons of datapoints on each player. In fact, anytime the Reds and Rockies play there’s always several intriguing angles to key in on. Not to mention games played at Coors Field in Apr can often follow normal, predictable patterns.
Remi's searched hard and found the best prop for this matchup: E. De La Cruz over 8.5 Fantasy Score.

Cincinnati vs. Colorado Prediction (AI)

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Remi, our AI sports wizard, has been pouring over exorbitant amounts of data from every facet between the Reds and Rockies and using recursive machine learning and kick-ass AI to crunch the data to a single cover probability.

Interestingly enough, the data has been most focused on the growing weight knucklehead sportsbettors regularly put on coaching factors between a Reds team going up against a possibly strong Rockies team. It appears the true game analytics might reflect a strong lean against one Vegas line specifically.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI Cincinnati vs Colorado picks, computer picks Reds vs Rockies, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
MLB 9/26 DET@BOS UNLOCK THIS PICK 5 EXECUTIVE Locked EXECUTIVE
MLB 9/26 BAL@NYY UNLOCK THIS PICK 4 INTEL Locked INTEL
MLB 9/26 ARI@SD UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
MLB 9/26 NYM@MIA UNLOCK THIS PICK 1 INTEL Locked INTEL
MLB 9/26 NYM@MIA GET FREE PICK NOW 1
MLB 9/26 COL@SF UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Reds Betting Trends

The Reds have been solid against the spread (ATS) on the road, posting a 7–4 record in their last 11 away games. Their consistent performance has made them a reliable pick for bettors in recent matchups.

Rockies Betting Trends

The Rockies have struggled ATS at home, with a 4–11 record in their last 15 home games. Their inconsistent play has made it challenging for bettors to back them confidently.

Reds vs. Rockies Matchup Trends

In head-to-head matchups, the Reds have covered the spread in four of their last six games against the Rockies. Additionally, the total runs have gone over in five of the last seven meetings between these two teams, indicating a trend toward high-scoring affairs.

Cincinnati vs. Colorado Game Info

Cincinnati vs Colorado starts on April 26, 2025 at 3:10 PM EST.

Spread: Colorado +1.5
Moneyline: Cincinnati -192, Colorado +160
Over/Under: 10.5

Cincinnati: (13-13)  |  Colorado: (4-21)

Remi's searched hard and found the best prop for this matchup: E. De La Cruz over 8.5 Fantasy Score.. Prices move—always shop for the best number.

In head-to-head matchups, the Reds have covered the spread in four of their last six games against the Rockies. Additionally, the total runs have gone over in five of the last seven meetings between these two teams, indicating a trend toward high-scoring affairs.

CIN trend: The Reds have been solid against the spread (ATS) on the road, posting a 7–4 record in their last 11 away games. Their consistent performance has made them a reliable pick for bettors in recent matchups.

COL trend: The Rockies have struggled ATS at home, with a 4–11 record in their last 15 home games. Their inconsistent play has made it challenging for bettors to back them confidently.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Cincinnati vs. Colorado Odds

AI algorithm Remi is pouring through loads of stats on each line. In fact, anytime the Cincinnati vs Colorado trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme travel distance almost always follow normal, predictable betting trends.

Cincinnati vs Colorado Opening Odds

CIN Moneyline: -192
COL Moneyline: +160
CIN Spread: -1.5
COL Spread: +1.5
Over/Under: 10.5

Cincinnati vs Colorado Live Odds

Games PTS ML SPR O/U
Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
Orioles
Yankees
+190
-235
+1.5 (-110)
-1.5 (-110)
O 8.5 (-120)
U 8.5 (+100)
Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
 
-175
 
-1.5 (+115)
O 9.5 (-105)
U 9.5 (-115)
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
+130
-155
+1.5 (-155)
-1.5 (+130)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:06PM
White Sox
Nationals
+100
-120
-1.5 (+165)
+1.5 (-200)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
+185
-225
+1.5 (-110)
-1.5 (-110)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
-130
+110
-1.5 (+125)
+1.5 (-150)
O 8.5 (-105)
U 8.5 (-115)
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
+170
-205
+1.5 (-120)
-1.5 (+100)
O 8.5 (-115)
U 8.5 (-105)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+125
-150
+1.5 (-180)
-1.5 (+150)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+140
-170
+1.5 (-155)
-1.5 (+130)
O 8 (-110)
U 8 (-110)
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
+135
-165
+1.5 (-180)
-1.5 (+150)
O 7 (-120)
U 7 (+100)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+115
-140
+1.5 (-190)
-1.5 (+155)
O 7.5 (-120)
U 7.5 (+100)
Sep 27, 2025 9:39PM EDT
Houston Astros
Los Angeles Angels
9/27/25 9:39PM
Astros
Angels
-165
+135
-1.5 (+105)
+1.5 (-125)
O 9 (+100)
U 9 (-120)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+100
-120
-1.5 (+170)
+1.5 (-205)
O 7.5 (-110)
U 7.5 (-110)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
+100
-120
-1.5 (+150)
+1.5 (-180)
O 10 (-110)
U 10 (-110)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Cincinnati Reds vs. Colorado Rockies on April 26, 2025 at Coors Field.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS
CIN@ARI KEBRYAN HAYES STRIKEOUTS UNDER 0.5 56.2% 6 WIN
LAD@SD SD +110 50.9% 6 WIN