White Sox vs. Athletics
Prediction, Odds & Props
Apr 26 | MLB AI Picks

Updated: 2025-04-24T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Chicago White Sox (6–19) face the Oakland Athletics (11–13) on Saturday, April 26, 2025, at Sutter Health Park in Sacramento, California, with first pitch scheduled for 3:05 p.m. CDT. Both teams aim to gain momentum in this early-season American League matchup.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Apr 26, 2025

Start Time: 4:05 PM EST​

Venue: Sutter Health Park​

Athletics Record: (13-13)

White Sox Record: (6-20)

OPENING ODDS

CHW Moneyline: +185

ATH Moneyline: -224

CHW Spread: +1.5

ATH Spread: -1.5

Over/Under: 9

CHW
Betting Trends

  • The White Sox have struggled against the spread (ATS) recently, going 2–8 in their last 10 games. Their inconsistent performance has made them a challenging pick for bettors.

ATH
Betting Trends

  • The Athletics have been more reliable ATS at home, posting a 6–4 record in their last 10 home games. Their strong home performance has contributed positively to their ATS record.

MATCHUP TRENDS

  • In head-to-head matchups, the Athletics have covered the spread in five of their last seven games against the White Sox. Additionally, the total runs have gone over in six of the last eight meetings between these two teams, indicating a trend toward high-scoring affairs.

CHW vs. ATH
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: T. Soderstrom over 1.5 Hits+Runs+RBI.

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Chicago White Sox vs Athletics Prediction & Odds:
Free MLB Betting Insights for 4/26/25

The Chicago White Sox and Oakland Athletics face off on April 26, 2025, at Sutter Health Park in Sacramento in a matchup between two teams looking to find footing in the early stages of the MLB season, though their trajectories have been notably different. The White Sox enter this game with a dismal 6–19 record, stuck in a downward spiral where both offense and pitching have underperformed, while the Athletics, at 11–13, have shown signs of life and resilience, particularly at home, where they have been more competitive and reliable. Chicago will turn to right-hander Jonathan Cannon, still searching for his first career MLB win after posting an 0–3 record with a 4.81 ERA thus far, and hoping to bring some stability to a rotation that has failed to deliver consistent quality starts. Opposing him will be Oakland’s left-hander Jeffrey Springs, who carries a 3–2 record and a 5.64 ERA into the matchup, looking to bounce back after a few uneven outings but still offering flashes of the swing-and-miss ability that has made him a valuable piece of the Athletics’ staff. Offensively, the White Sox have leaned heavily on Andrew Benintendi and Luis Robert Jr. to drive production, but a lack of depth in the lineup has often left rallies stranded, leading to mounting frustration and minimal run support for their pitchers. Meanwhile, the Athletics have benefited from the hot bats of Brent Rooker and JJ Bleday, both of whom have provided much-needed middle-of-the-order pop to a team otherwise struggling to maintain consistency at the plate.

Defensively, neither team has been sharp, but Oakland has shown slight improvement recently, whereas defensive miscues continue to plague Chicago at critical moments, turning manageable innings into high-scoring disasters. The bullpens have also played a role in shaping each team’s fortunes, with Oakland’s relievers providing just enough stability to close out games, while the White Sox bullpen has been an unreliable group, often surrendering leads and compounding the team’s late-game issues. Recent head-to-head trends favor the Athletics, who have covered the spread in five of their last seven meetings with the White Sox, and the trend toward higher-scoring affairs between these two clubs suggests that both starters will need to be sharp to avoid early trouble. For the White Sox, the path to victory requires a strong outing from Cannon, clean defense behind him, and timely hitting to finally push some pressure back onto their opponents. For the Athletics, the game plan revolves around early offensive pressure, solid innings from Springs, and letting their improved bullpen protect whatever lead they can establish. With both teams looking to shift momentum in their favor, but particularly Chicago desperate for any kind of positive sign, Saturday’s contest promises urgency and energy, even if it may lack the marquee value of a high-profile series elsewhere. For Oakland, it’s a chance to inch closer to .500 and continue building confidence; for the White Sox, it’s simply about survival and hoping to spark the turnaround that has eluded them so far this season.

Chicago White Sox White Sox MLB Preview

The Chicago White Sox come into Saturday’s matchup against the Oakland Athletics desperate for any signs of life, carrying a bleak 6–19 record that reflects the numerous struggles they have faced through the first month of the 2025 season. The White Sox have been plagued by inconsistent pitching, defensive lapses, and an offense that has failed to deliver in high-leverage situations, all contributing to a start that has put them deep in the AL Central basement. Right-hander Jonathan Cannon takes the mound, still in search of his first Major League win with an 0–3 record and a 4.81 ERA, showing flashes of promise but lacking the support he needs from his teammates to convert quality outings into victories. Cannon’s ability to command his fastball and avoid the big inning will be crucial against an Athletics lineup that, while not overpowering, has capitalized on mistakes from opposing pitchers.

Offensively, Chicago leans heavily on Andrew Benintendi and Luis Robert Jr., both of whom have been bright spots in an otherwise disappointing lineup, but too often the White Sox have struggled to drive runners home once they reach scoring position. The lack of depth in the batting order and the frequent reliance on solo home runs rather than sustained rallies has made manufacturing runs a challenge. Defensively, the White Sox continue to undermine themselves with untimely errors, adding unnecessary pressure to a pitching staff that is already fighting an uphill battle. Manager Pedro Grifol faces the difficult task of keeping his players engaged and motivated amid a demoralizing string of losses, and changes to the lineup or defensive alignments could be on the horizon if results do not improve soon. A win on Saturday would not erase the issues plaguing the White Sox but would at least provide a desperately needed morale boost as they try to salvage something positive from a disappointing road trip. Success will depend on clean defense, opportunistic hitting, and Cannon’s ability to keep the game within reach long enough for the offense to break through.

The Chicago White Sox (6–19) face the Oakland Athletics (11–13) on Saturday, April 26, 2025, at Sutter Health Park in Sacramento, California, with first pitch scheduled for 3:05 p.m. CDT. Both teams aim to gain momentum in this early-season American League matchup. Chicago White Sox vs Athletics AI Prediction: Free MLB Betting Insights for Apr 26. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Athletics Athletics MLB Preview

The Oakland Athletics enter Saturday’s game against the Chicago White Sox with cautious optimism, holding an 11–13 record and seeing tangible signs of growth after a rocky start to their 2025 season. Playing at Sutter Health Park has been a relative bright spot, with the Athletics showing much-improved energy and execution at home compared to their early road struggles. Left-hander Jeffrey Springs will get the start, carrying a 3–2 record and a 5.64 ERA into the contest; while his numbers suggest inconsistency, he has demonstrated an ability to generate swings and misses when he commands his changeup and keeps hitters off balance. Springs will be tasked with shutting down a White Sox lineup that has struggled to string together consistent rallies, making early efficiency critical so that Oakland’s bullpen can avoid heavy early usage. Offensively, the Athletics have found production from Brent Rooker, whose power bat has made him a fixture in the heart of the order, and JJ Bleday, who has provided key hits and improved his on-base percentage, giving the team more scoring opportunities. Oakland’s offense has not been explosive but has been opportunistic, taking advantage of opponent mistakes and delivering timely hits in recent games.

Defensively, the Athletics have made noticeable strides, reducing costly errors and providing better support for their pitchers, particularly in late-game situations where clean execution has helped preserve narrow leads. Manager Mark Kotsay has shown a steady hand with the bullpen, utilizing favorable matchups and leaning on trusted arms like Mason Miller to close out games when given a lead. The Athletics’ strategy for Saturday is clear: get Springs into the middle innings with a lead, maintain aggressive but disciplined approaches at the plate to wear down White Sox starter Jonathan Cannon, and continue playing fundamentally sound defense. A win against Chicago would move Oakland closer to the .500 mark and reinforce the belief that, while they may not be playoff contenders just yet, they are building a competitive, resilient ballclub capable of giving opponents fits all season long. Maintaining momentum through April is crucial for a young team trying to establish a new identity, and Saturday’s game offers a prime opportunity to continue that growth against a struggling White Sox squad.

Chicago White Sox vs. Athletics Prop Picks (AI)

Remi is pouring through loads of stats on each team. In fact, anytime the White Sox and Athletics play there’s always several intriguing trends to key in on. Not to mention games played at Sutter Health Park in Apr almost always follow normal, predictable patterns.
Remi's searched hard and found the best prop for this matchup: T. Soderstrom over 1.5 Hits+Runs+RBI.

Chicago White Sox vs. Athletics Prediction (AI)

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Remi, our AI sports wizard, has been pouring over millions of data from every facet between the White Sox and Athletics and using recursive machine learning and kick-ass AI to analyze the data to a single cover probability.

The Algorithm has been most fixated on the growing weight emotional bettors tend to put on coaching factors between a White Sox team going up against a possibly healthy Athletics team. In reality, the true game analytics might reflect a strong lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI Chicago White Sox vs Athletics picks, computer picks White Sox vs Athletics, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

White Sox Betting Trends

The White Sox have struggled against the spread (ATS) recently, going 2–8 in their last 10 games. Their inconsistent performance has made them a challenging pick for bettors.

Athletics Betting Trends

The Athletics have been more reliable ATS at home, posting a 6–4 record in their last 10 home games. Their strong home performance has contributed positively to their ATS record.

White Sox vs. Athletics Matchup Trends

In head-to-head matchups, the Athletics have covered the spread in five of their last seven games against the White Sox. Additionally, the total runs have gone over in six of the last eight meetings between these two teams, indicating a trend toward high-scoring affairs.

Chicago White Sox vs. Athletics Game Info

Chicago White Sox vs Athletics starts on April 26, 2025 at 4:05 PM EST.

Spread: Athletics -1.5
Moneyline: Chicago White Sox +185, Athletics -224
Over/Under: 9

Chicago White Sox: (6-20)  |  Athletics: (13-13)

Remi's searched hard and found the best prop for this matchup: T. Soderstrom over 1.5 Hits+Runs+RBI.. Prices move—always shop for the best number.

In head-to-head matchups, the Athletics have covered the spread in five of their last seven games against the White Sox. Additionally, the total runs have gone over in six of the last eight meetings between these two teams, indicating a trend toward high-scoring affairs.

CHW trend: The White Sox have struggled against the spread (ATS) recently, going 2–8 in their last 10 games. Their inconsistent performance has made them a challenging pick for bettors.

ATH trend: The Athletics have been more reliable ATS at home, posting a 6–4 record in their last 10 home games. Their strong home performance has contributed positively to their ATS record.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Chicago White Sox vs. Athletics Odds

Remi is pouring through mountains of data points on each line. In fact, anytime the Chicago White Sox vs Athletics trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme travel distance almost always follow normal, predictable betting trends.

Chicago White Sox vs Athletics Opening Odds

CHW Moneyline: +185
ATH Moneyline: -224
CHW Spread: +1.5
ATH Spread: -1.5
Over/Under: 9

Chicago White Sox vs Athletics Live Odds

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Sep 27, 2025 7:15PM EDT
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Sep 27, 2025 7:16PM EDT
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Sep 27, 2025 8:40PM EDT
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9/27/25 8:40PM
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+130
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Sep 27, 2025 9:39PM EDT
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9/27/25 9:39PM
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-146
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Sep 27, 2025 9:41PM EDT
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9/27/25 9:41PM
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U 10 (-106)
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9/28/25 3:06PM
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U 9 (+100)
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+270
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+180
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MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Chicago White Sox White Sox vs. Athletics Athletics on April 26, 2025 at Sutter Health Park.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
ARI@SD SD -131 57.3% 4 WIN
DET@BOS BOS -115 56.4% 5 WIN
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS