White Sox vs Athletics Prediction — AI Finds CAN'T MISS MLB Lines & Props (Apr 25)
Updated: 2025-04-23T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
On April 25, 2025, the Chicago White Sox (5–18) will face the Athletics (10–12) at Sutter Health Park in West Sacramento, California, with first pitch scheduled for 10:05 p.m. ET. The Athletics are favored at -235 on the moneyline, while the White Sox are listed at +193, and the over/under is set at 9 runs.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.
GAME INFO
Date: Apr 25, 2025
Start Time: 10:05 PM EST
Venue: Sutter Health Park
Athletics Record: (12-13)
White Sox Record: (6-19)
OPENING ODDS
CHW Moneyline: +192
ATH Moneyline: -234
CHW Spread: +1.5
ATH Spread: -1.5
Over/Under: 9
CHW
Betting Trends
- The White Sox have a 1–10 record on the road this season.
ATH
Betting Trends
- The Athletics have a 6–4 record against the spread (ATS) over their past 10 games.
MATCHUP TRENDS
- In their last 5 head-to-head matchups, the Athletics have covered the spread in 60% of the games, while the White Sox have covered in 40%.
CHW vs. ATH
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: L. Butler over 7 Fantasy Score.
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Chicago White Sox vs Athletics Prediction & Odds:
Free MLB Betting Insights for 4/25/25
At the plate, the Athletics have benefited from strong top-of-the-order presence and clutch hitting from the likes of Jacob Wilson, who enters the series hitting .354 and giving the lineup crucial contact and on-base ability. This version of Oakland isn’t overpowering, but they’re clean, opportunistic, and motivated, especially as they navigate a season filled with doubters. Against a Chicago team that’s been bleeding runs and chasing deficits, the A’s know this series opener is their chance to assert control early and potentially build toward a .500 record heading into May. For the White Sox, this game is an opportunity to start climbing out of a deep early-season hole, but the obstacles are many. The offense has been punchless in key spots despite glimmers of hope from players like Miguel Vargas and Lenyn Sosa, who have contributed with multi-hit games and occasional flashes of pop. Still, the lack of sustained rallies and an inability to extend innings has made it tough to support a pitching staff that desperately needs run insurance. Gilbert will need to pitch well beyond his track record to give Chicago a fighting chance, and even then, the bullpen will need to show marked improvement after weeks of instability and late-game letdowns. The path to success for the White Sox involves limiting mistakes, forcing Oakland into early-inning slumps, and finally stringing together quality at-bats—something they’ve failed to do in nearly every road series so far this season. If Chicago can’t capitalize on scoring opportunities or tighten up defensively, they risk allowing the Athletics to control tempo and confidence, two things the A’s have built up in recent weeks. For the White Sox, this isn’t just another road game—it’s a turning point in a season that’s already approaching critical mass. A win would do more than pad the standings—it could restore belief in a roster that badly needs to rediscover its identity.
Shane Smith was filthy today 😮💨 pic.twitter.com/9EOlPcETR6
— Chicago White Sox (@whitesox) April 24, 2025
Chicago White Sox White Sox MLB Preview
The Chicago White Sox enter their April 25, 2025 matchup against the Athletics with the worst record in baseball at 5–18, and they are a team clearly in freefall searching for any form of momentum or identity as the first month of the season draws to a close. Their road woes have been especially pronounced, with just one win in 11 tries away from home, and that poor showing is directly tied to the team’s inability to pitch effectively in the early innings or generate enough offense to stay within striking distance. Southpaw Tyler Gilbert will take the mound in hopes of providing a spark for a rotation that’s cycled through arms with minimal success; Gilbert has shown flashes of control but hasn’t yet proven he can consistently navigate opposing lineups with the kind of presence required to give the White Sox six competitive innings. With Chicago’s bullpen already stretched thin from short outings and late-game collapses, the pressure on Gilbert is immense—not only to prevent runs, but to spare the relievers from more high-leverage damage. It’s a tall order against an Athletics lineup featuring red-hot bats like Tyler Soderstrom, and given the White Sox’s ongoing defensive lapses, Gilbert will need pinpoint command and solid ground-ball execution to have any chance of avoiding early trouble. On offense, the White Sox have struggled to deliver when it matters most, failing to capitalize with runners in scoring position and lacking the kind of lineup depth needed to mount consistent rallies. Miguel Vargas and Lenyn Sosa have provided some much-needed sparks in recent games, showing gap-to-gap ability and contributing extra-base hits, but their efforts haven’t been enough to cover for the broader inefficiency of the team’s at-bats.
Chicago is batting near the bottom of the league in runs scored, and the lack of plate discipline and contact quality has translated into quick innings and little sustained pressure on opposing pitchers. Against Luis Severino, a veteran right-hander with the ability to exploit overaggressive hitters with sharp breaking stuff, the White Sox will need to stay patient, work deep counts, and manufacture opportunities with smart baserunning and aggressive situational play. If they revert to the form that’s led to so many early exits and scoreless stretches, they’ll find themselves chasing yet another deficit and asking a bullpen that’s consistently faltered to clean up the mess. This game represents a crucial opportunity for the White Sox to show they’re still capable of fighting out of adversity, even if the odds are firmly stacked against them. It’s not about turning the season around in one night—it’s about breaking habits that have defined the first three weeks: sloppy defense, quiet bats, and ineffective starting pitching. If Gilbert can keep the ball in the park and Vargas and Sosa can continue to create at the plate, Chicago may have the pieces to at least remain competitive in this series opener. But without sharp execution and better in-game management, the White Sox will likely continue to drift in a season that’s slipping away fast, especially as stronger opponents begin to pile up on the calendar. A win in Oakland wouldn’t erase the losses, but it would offer something the White Sox haven’t had in weeks—hope.
Credit: USA TODAY/IMAGN
Athletics Athletics MLB Preview
The Athletics return to Sutter Health Park on April 25, 2025, to host the struggling Chicago White Sox in a matchup that presents a clear opportunity to capitalize on recent momentum and inch closer to the .500 mark. At 10–12, the A’s have outperformed modest preseason expectations, and with solid home-field play and an improving rotation, they appear to be trending upward. Veteran right-hander Luis Severino will start the opener and look to build upon his recent consistency, bringing an edge and experience that’s helped anchor a staff still finding its identity. Severino’s effectiveness has stemmed from a sharpened command of his fastball-slider combination and a more composed approach on the mound, allowing him to neutralize middle-of-the-order bats and pitch deep enough to minimize bullpen strain. Facing a White Sox lineup that has been among the league’s worst in runs scored and batting average, Severino will likely challenge hitters early in the count and pitch to contact against a team that’s struggled to extend innings. With a defense that’s limited mistakes and a bullpen that’s held its own in recent weeks, the Athletics are well-positioned to control tempo if Severino delivers even an average-quality start. Offensively, the Athletics have found a groove, led by breakout slugger Tyler Soderstrom, whose nine home runs and 19 RBIs have made him one of the most dangerous hitters in the American League this month. Soderstrom’s ability to launch the ball to all fields and work counts has turned him into a nightly threat, while the supporting cast—including contact machine Jacob Wilson, batting .354—has helped stretch the lineup and create frequent scoring opportunities.
What sets Oakland apart right now isn’t overwhelming power up and down the order, but a balanced approach that emphasizes patient at-bats, line-drive contact, and speed on the bases. Against White Sox left-hander Tyler Gilbert, the A’s will likely lean on aggressive early swings from right-handed hitters and a willingness to exploit Gilbert’s tendency to fall behind in counts. Given Chicago’s defensive inefficiencies and bullpen volatility, the Athletics should look to press early and force the White Sox into reactive, high-stress pitching situations—something Oakland has done well during recent series wins. This game represents more than just a chance for the Athletics to stack another win; it’s an opportunity to show they can consistently beat the teams they’re expected to beat—something essential for any club hoping to remain relevant through the summer. With Severino’s veteran presence on the mound, Soderstrom’s middle-of-the-order power, and an increasingly confident clubhouse, Oakland has all the ingredients to not only win this series opener but to control it from the first pitch. Discipline, execution, and clean defense will be the key—three elements the Athletics have increasingly delivered throughout April. If they continue on that path, this game could mark the start of a crucial stretch where Oakland redefines its ceiling for 2025 and plants itself more firmly in the conversation within the AL West. Against a White Sox team clearly searching for answers, the Athletics don’t just have the edge—they have the momentum.
stay for the celly !!!!! pic.twitter.com/HCHcudqUBP
— Athletics (@Athletics) April 25, 2025
Chicago White Sox vs. Athletics Prop Picks (AI)
Chicago White Sox vs. Athletics Prediction (AI)
Remi, our AI sports algorithm, has been pouring over millions of data from every facet between the White Sox and Athletics and using recursive machine learning and industry leading AI to analyze the data to a single cover probability.
The Algorithm has been most fixated on the linear correlation of factor human bettors tend to put on coaching factors between a White Sox team going up against a possibly healthy Athletics team. We’ve found the true game analytics might reflect a slight lean against one Vegas line specifically.
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Below is our current AI Chicago White Sox vs Athletics picks, computer picks White Sox vs Athletics, best bets, model edges, confidence ratings.
| DATE | GAME | LEAN | %WIN | UNITS | LEVEL | |
|---|---|---|---|---|---|---|
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.
White Sox Betting Trends
The White Sox have a 1–10 record on the road this season.
Athletics Betting Trends
The Athletics have a 6–4 record against the spread (ATS) over their past 10 games.
White Sox vs. Athletics Matchup Trends
In their last 5 head-to-head matchups, the Athletics have covered the spread in 60% of the games, while the White Sox have covered in 40%.
Chicago White Sox vs. Athletics Game Info
What time does Chicago White Sox vs Athletics start on April 25, 2025?
Chicago White Sox vs Athletics starts on April 25, 2025 at 10:05 PM EST.
Where is Chicago White Sox vs Athletics being played?
Venue: Sutter Health Park.
What are the opening odds for Chicago White Sox vs Athletics?
Spread: Athletics -1.5
Moneyline: Chicago White Sox +192, Athletics -234
Over/Under: 9
What are the records for Chicago White Sox vs Athletics?
Chicago White Sox: (6-19) | Athletics: (12-13)
What is the AI best bet for Chicago White Sox vs Athletics?
Remi's searched hard and found the best prop for this matchup: L. Butler over 7 Fantasy Score.. Prices move—always shop for the best number.
What are Chicago White Sox vs Athletics trending bets?
In their last 5 head-to-head matchups, the Athletics have covered the spread in 60% of the games, while the White Sox have covered in 40%.
What are Chicago White Sox trending bets?
CHW trend: The White Sox have a 1–10 record on the road this season.
What are Athletics trending bets?
ATH trend: The Athletics have a 6–4 record against the spread (ATS) over their past 10 games.
Where can I find AI Picks for Chicago White Sox vs Athletics?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
Chicago White Sox vs. Athletics Odds
AI algorithm Remi is pouring through tons of data points on each line. In fact, anytime the Chicago White Sox vs Athletics trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme travel distance can often follow normal, predictable betting trends.
Chicago White Sox vs Athletics Opening Odds
CHW Moneyline:
+192 ATH Moneyline: -234
CHW Spread: +1.5
ATH Spread: -1.5
Over/Under: 9
Chicago White Sox vs Athletics Live Odds
| Games | PTS | ML | SPR | O/U |
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MLB Past Picks
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This preview covers Chicago White Sox White Sox vs. Athletics Athletics on April 25, 2025 at Sutter Health Park.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
| LEAN | %WIN | UNITS | RESULT | |
|---|---|---|---|---|
| LAD@TOR | TOR +1.5 | 56.7% | 2 | WIN |
| TOR@LAD | TOR +1.5 | 55.3% | 4 | WIN |
| TOR@SEA | OVER 7 | 54.9% | 3 | WIN |
| LAD@MIL | UNDER 7.5 | 56.6% | 6 | WIN |
| TOR@NYY | OVER 8 | 54.9% | 4 | WIN |
| TOR@NYY | CARLOS RODON OVER 1.5 TOTAL WALKS ALLOWED | 53.3% | 3 | WIN |
| NYY@TOR | OVER 7.5 | 54.8% | 2 | WIN |
| LAD@PHI | OVER 7 | 53.8% | 3 | WIN |
| SD@CHC | CHC -109 | 53.8% | 3 | WIN |
| SD@CHC | OVER 7.5 | 54.5% | 4 | LOSS |
| SD@CHC | CHC -111 | 54.8% | 4 | LOSS |
| CIN@LAD | SHOHEI OHTANI OVER 1.5 BASES | 53.5% | 3 | WIN |
| BOS@NYY | OVER 7 | 53.8% | 3 | LOSS |
| CIN@LAD | ELLY DE LA CRUZ OVER 0.5 BASES | 54.4% | 4 | LOSS |
| ARI@SD | SD -131 | 57.3% | 4 | WIN |
| DET@BOS | BOS -115 | 56.4% | 5 | WIN |
| NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
| HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
| NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
| STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
| KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
| MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
| MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
| WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
| LAA@COL | COL +108 | 50.5% | 3 | WIN |
| TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
| SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
| NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
| MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
| MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
| SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
| PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
| NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
| KC@PHI | PHI -130 | 58.3% | 4 | WIN |
| LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
| NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
| KC@CLE | KC -104 | 52.0% | 3 | WIN |
| CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
| WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
| LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
| TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
| SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
| SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
| MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
| NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
| TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
| TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
| ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
| PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
| ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
| SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |