Brewers vs. Giants
Prediction, Odds & Props
Apr 24 | MLB AI Picks

Updated: 2025-04-22T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Milwaukee Brewers and San Francisco Giants will conclude their four-game series at Oracle Park on April 24, 2025. The Giants aim to capitalize on their home-field advantage, while the Brewers seek to even the series before returning home.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Apr 24, 2025

Start Time: 3:45 PM EST​

Venue: Oracle Park​

Giants Record: (16-9)

Brewers Record: (13-12)

OPENING ODDS

MIL Moneyline: +119

SF Moneyline: -140

MIL Spread: +1.5

SF Spread: -1.5

Over/Under: 7.5

MIL
Betting Trends

  • The Brewers have covered the spread in 3 of their last 10 games.

SF
Betting Trends

  • The Giants have covered the spread in 6 of their last 10 games.

MATCHUP TRENDS

  • The Giants are favored with a -146 moneyline, while the Brewers are at +122. The over/under for the game is set at 6.5 runs.

MIL vs. SF
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: T. Fitzgerald over 0.5 Total Bases.

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Milwaukee vs San Francisco Prediction & Odds:
Free MLB Betting Insights for 4/24/25

The Milwaukee Brewers and San Francisco Giants will conclude a competitive four-game series on April 24, 2025, at Oracle Park in San Francisco, with both teams looking to capitalize on early-season momentum in what’s shaping up to be a pivotal matchup for National League positioning. The Giants currently sit at 16-9, a strong start that has them contending near the top of the NL West, while the Brewers arrive at 13-12, locked in a tight NL Central race and trying to establish consistency amid a stretch of tough road games. San Francisco has won two of the first three games in this series, including a low-scoring 2-1 victory that underscored their ability to control games with sharp pitching and timely execution. For the Brewers, who have shown flashes of offensive potential throughout the season, this series has revealed some vulnerabilities—namely, their occasional lack of run production against top-tier pitching and a bullpen that has struggled at times to hold narrow leads. Statistically, both teams are closely matched, with the Giants averaging 4.64 runs per game compared to Milwaukee’s 4.38, while San Francisco’s superior run prevention (3.48 runs allowed per game versus Milwaukee’s 4.00) has made the difference thus far in the series. Thursday’s pitching matchup will feature Tobias Myers for Milwaukee and Landen Roupp for San Francisco, a duel between two arms with very different trajectories. Roupp has been a bright spot in the Giants’ rotation, entering the game with a 2-1 record and a 4.09 ERA while showing poise and command in critical innings.

His ability to pitch efficiently and mix speeds has allowed him to limit damage and go deep into games, reducing pressure on a bullpen that has already logged considerable work this month. Myers, on the other hand, is still searching for rhythm in Milwaukee’s rotation and will be tasked with containing a San Francisco lineup that has steadily produced with runners on base, especially in late-inning situations. The Brewers will need a quality outing from Myers to remain competitive, particularly given the recent fatigue among relievers and the challenges of scoring at Oracle Park, a stadium that traditionally favors pitchers. Milwaukee’s offense will lean heavily on key contributors like Willy Adames, William Contreras, and Christian Yelich to generate run support, particularly early in the game when the Giants tend to establish control from the mound. For the Giants, maintaining their edge will come down to continuing their disciplined approach at the plate and executing defensively—areas in which they’ve excelled over the first three weeks of the season. Their pitching staff, which has limited the Brewers to modest run totals thus far, will look to set the tone again behind Roupp, while the offense will aim to apply pressure on Myers through patient at-bats and timely aggression on the basepaths. If San Francisco can win this game and take three out of four in the series, it would further solidify their status as a legitimate division threat and affirm their home-field advantage as a weapon throughout the season. On the other side, the Brewers view this finale as an opportunity to grab a hard-fought series split and prove they can match up with the league’s better clubs on the road—something they’ll need to do regularly to remain relevant in the NL playoff picture.

Milwaukee Brewers MLB Preview

The Milwaukee Brewers enter the final game of their four-game series against the San Francisco Giants with a chance to salvage a split and regain footing after a week of uneven play that has kept them hovering just above the .500 mark. At 13-12, Milwaukee remains firmly in the mix in the NL Central but continues to search for consistency in both their rotation and bullpen, which has been tested extensively during this West Coast swing. This finale carries added importance for the Brewers, not just to avoid a series loss, but to reestablish the brand of clean, opportunistic baseball that has historically defined their success. The offense, while producing a respectable 4.38 runs per game, has struggled to deliver in clutch spots throughout the series, leaving too many runners in scoring position and missing chances to swing momentum. Milwaukee’s big bats—Willy Adames, Christian Yelich, and William Contreras—have provided scattered bursts of production, but the club has lacked the type of inning-stretching consistency that allows them to sustain pressure on opposing pitching staffs. If the Brewers hope to reverse that trend in the series finale, they’ll need early production and smarter plate approaches against a Giants team that has managed to win low-scoring games by executing fundamentals better and capitalizing on their home field. On the mound for Milwaukee will be right-hander Tobias Myers, who steps into a pivotal role as the Brewers aim to stem the tide and avoid a third loss in four games. Myers has shown potential in flashes but remains unproven at the major league level and will face the challenge of navigating a San Francisco lineup that has been disciplined and opportunistic throughout this series.

Myers must establish command early, stay ahead in counts, and minimize walks if he hopes to avoid putting added pressure on a bullpen that has struggled to protect leads and handle close-game scenarios in recent weeks. The Brewers’ bullpen—featuring names like Joel Payamps, Elvis Peguero, and Hoby Milner—has been taxed, and Milwaukee needs Myers to provide quality innings to give their relievers a breather and a chance to reset. Defensively, the Brewers have been mostly sharp, and they’ll need to remain so in the finale, especially in tight scoring games where one miscue can shift the balance. Base running, outfield communication, and infield decision-making will all be magnified in a venue like Oracle Park, where runs can be scarce and execution is paramount. Ultimately, this game is about reasserting control for a Milwaukee team that has shown enough flashes to be considered a contender but lacks the consistency to separate itself from the middle of the NL pack. A win on Thursday would send them home from this road trip with confidence and momentum, reestablishing the foundation for a strong run into May. It’s also an important test of resilience—how the team responds to adversity, how the young arms hold up under pressure, and whether the veteran hitters can deliver when it counts. With divisional battles ahead and a playoff race that figures to be tight all season, games like this matter more than the standings may indicate. For the Brewers, a strong finish to this series could be the beginning of their climb from solid to serious in the National League landscape.

The Milwaukee Brewers and San Francisco Giants will conclude their four-game series at Oracle Park on April 24, 2025. The Giants aim to capitalize on their home-field advantage, while the Brewers seek to even the series before returning home. Milwaukee vs San Francisco AI Prediction: Free MLB Betting Insights for Apr 24. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

San Francisco Giants MLB Preview

The San Francisco Giants step into the series finale against the Milwaukee Brewers on April 24, 2025, at Oracle Park with a chance to claim a three-out-of-four series win and continue their strong early-season push in the National League. At 16-9, the Giants have emerged as one of the more consistent and balanced teams in the NL West, finding success through a blend of quality starting pitching, timely offense, and dependable bullpen execution. Their performance against the Brewers so far has reflected that formula: they’ve managed to stifle Milwaukee’s bats in critical moments while producing just enough offense to secure tight wins, including a 2-1 grinder that showcased their capacity to win low-scoring games. San Francisco’s lineup doesn’t rely on star power alone but instead features a cast of reliable contributors—players who grind out at-bats, move runners, and rarely waste scoring opportunities. Entering this matchup, they’re averaging 4.64 runs per game while allowing just 3.48, making them one of the more efficient two-way clubs in the National League. Thursday’s game gives them an opportunity to not only lock down another home series but to continue building their reputation as a fundamentally sound and playoff-ready team that can beat you in multiple ways. Starting for San Francisco will be Landen Roupp, a rising right-hander who enters the game with a 2-1 record, a 4.09 ERA, and a growing reputation for composure and adaptability on the mound. Roupp has impressed early in the season with his ability to get key outs and work deep into games, traits that have helped stabilize a rotation that faced questions entering the year. His success stems from a mature approach to pitch sequencing, mixing a sharp breaking ball with a lively fastball to keep hitters guessing.

Against a Brewers lineup that has shown power but lacked sustained offensive pressure in this series, Roupp’s command and rhythm will be essential to setting the tone. If he can get through the first few innings cleanly and avoid giving up early crooked numbers, it puts the game squarely in the hands of a Giants bullpen that has been dependable and versatile. Relievers like Camilo Doval and Taylor Rogers have been instrumental in closing out games, and with the Giants rarely giving up late leads, maintaining that strength remains a key part of their identity. San Francisco’s defensive play has also been sharp, and their ability to convert routine outs and avoid extra-base chaos has prevented opponents from gaining momentum even when they reach base. With the Dodgers and Padres close behind in the standings, the Giants understand the importance of stacking series wins in April to avoid playing catch-up later in the year. A victory in this finale not only caps off a successful home stand but affirms the team’s formula: disciplined offense, strong pitching, and clean execution. They’ll look to keep pressure on the Brewers early, manufacture runs through smart base running and productive outs, and trust their pitching to do the rest. If San Francisco continues to play at this level, they’ll not only remain a fixture in the NL West race but also position themselves for a legitimate playoff run. A win on Thursday would be another step in that direction—a statement that the Giants’ strong start is no fluke, but rather a product of structure, depth, and execution.

Milwaukee vs. San Francisco Prop Picks (AI)

Remi is pouring through loads of datapoints on each line. In fact, anytime the Brewers and Giants play there’s always several intriguing observations to key in on. Not to mention games played at Oracle Park in Apr seemingly never follow normal, predictable patterns.
Remi's searched hard and found the best prop for this matchup: T. Fitzgerald over 0.5 Total Bases.

Milwaukee vs. San Francisco Prediction (AI)

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Remi, our AI sports genius, has been pouring over exorbitant amounts of data from every past game between the Brewers and Giants and using recursive machine learning and impressive AI to analyze the data to a single cover probability.

Remi has been most fixated on the linear correlation of emphasis knucklehead sportsbettors often put on San Francisco’s strength factors between a Brewers team going up against a possibly rested Giants team. In reality, the true game analytics appear to reflect a slight lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI Milwaukee vs San Francisco picks, computer picks Brewers vs Giants, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
MLB 9/26 DET@BOS UNLOCK THIS PICK 5 EXECUTIVE Locked EXECUTIVE
MLB 9/26 BAL@NYY UNLOCK THIS PICK 4 INTEL Locked INTEL
MLB 9/26 ARI@SD UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
MLB 9/26 NYM@MIA UNLOCK THIS PICK 1 INTEL Locked INTEL
MLB 9/26 NYM@MIA GET FREE PICK NOW 1
MLB 9/26 COL@SF UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Brewers Betting Trends

The Brewers have covered the spread in 3 of their last 10 games.

Giants Betting Trends

The Giants have covered the spread in 6 of their last 10 games.

Brewers vs. Giants Matchup Trends

The Giants are favored with a -146 moneyline, while the Brewers are at +122. The over/under for the game is set at 6.5 runs.

Milwaukee vs. San Francisco Game Info

Milwaukee vs San Francisco starts on April 24, 2025 at 3:45 PM EST.

Spread: San Francisco -1.5
Moneyline: Milwaukee +119, San Francisco -140
Over/Under: 7.5

Milwaukee: (13-12)  |  San Francisco: (16-9)

Remi's searched hard and found the best prop for this matchup: T. Fitzgerald over 0.5 Total Bases.. Prices move—always shop for the best number.

The Giants are favored with a -146 moneyline, while the Brewers are at +122. The over/under for the game is set at 6.5 runs.

MIL trend: The Brewers have covered the spread in 3 of their last 10 games.

SF trend: The Giants have covered the spread in 6 of their last 10 games.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Milwaukee vs. San Francisco Odds

AI algorithm Remi is pouring through mountains of data points on each team. In fact, anytime the Milwaukee vs San Francisco trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme altitude almost always follow normal, predictable betting trends.

Milwaukee vs San Francisco Opening Odds

MIL Moneyline: +119
SF Moneyline: -140
MIL Spread: +1.5
SF Spread: -1.5
Over/Under: 7.5

Milwaukee vs San Francisco Live Odds

Games PTS ML SPR O/U
Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
Orioles
Yankees
+190
-235
+1.5 (-110)
-1.5 (-110)
O 8.5 (-120)
U 8.5 (+100)
Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
 
-175
 
-1.5 (+115)
O 9.5 (-105)
U 9.5 (-115)
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
+130
-155
+1.5 (-155)
-1.5 (+130)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:06PM
White Sox
Nationals
+100
-120
-1.5 (+165)
+1.5 (-200)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
+185
-225
+1.5 (-110)
-1.5 (-110)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
-130
+110
-1.5 (+125)
+1.5 (-150)
O 8.5 (-105)
U 8.5 (-115)
Sep 27, 2025 4:11PM EDT
Detroit Tigers
Boston Red Sox
9/27/25 4:11PM
Tigers
Red Sox
 
 
pk
pk
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
+170
-205
+1.5 (-120)
-1.5 (+100)
O 8.5 (-115)
U 8.5 (-105)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+125
-150
+1.5 (-180)
-1.5 (+150)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+140
-170
+1.5 (-155)
-1.5 (+130)
O 8 (-110)
U 8 (-110)
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
+135
-165
+1.5 (-180)
-1.5 (+150)
O 7 (-120)
U 7 (+100)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+115
-140
+1.5 (-190)
-1.5 (+155)
O 7.5 (-120)
U 7.5 (+100)
Sep 27, 2025 9:39PM EDT
Houston Astros
Los Angeles Angels
9/27/25 9:39PM
Astros
Angels
-165
+135
-1.5 (+105)
+1.5 (-125)
O 9 (+100)
U 9 (-120)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+100
-120
-1.5 (+170)
+1.5 (-205)
O 7.5 (-110)
U 7.5 (-110)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
+100
-120
-1.5 (+150)
+1.5 (-180)
O 10 (-110)
U 10 (-110)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Milwaukee Brewers vs. San Francisco Giants on April 24, 2025 at Oracle Park.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS
CIN@ARI KEBRYAN HAYES STRIKEOUTS UNDER 0.5 56.2% 6 WIN
LAD@SD SD +110 50.9% 6 WIN