Padres vs. Tigers
Prediction, Odds & Props
Apr 23 | MLB AI Picks

Updated: 2025-04-21T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The San Diego Padres (16-7) and Detroit Tigers (14-9) conclude their three-game series at Comerica Park on April 23, 2025, with first pitch scheduled for 1:10 p.m. ET. The Padres aim to secure a series win, while the Tigers look to defend their strong home record.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Apr 23, 2025

Start Time: 1:10 PM EST​

Venue: Comerica Park​

Tigers Record: (14-10)

Padres Record: (17-7)

OPENING ODDS

SD Moneyline: +135

DET Moneyline: -160

SD Spread: +1.5

DET Spread: -1.5

Over/Under: 8.5

SD
Betting Trends

  • The Padres have covered the run line in 8 of their last 10 games, demonstrating strong performance against the spread. However, they are 2-4 ATS in their last 6 games when playing on the road against Detroit.

DET
Betting Trends

  • The Tigers are 9-4 ATS in their last 13 games and have covered the spread in 6 of their last 7 home games. They are also 4-2 ATS in their last 6 games when playing at home against San Diego.

MATCHUP TRENDS

  • The total has gone UNDER in 4 of San Diego’s last 5 games, indicating a trend toward low-scoring contests. Additionally, Detroit is 8-2 SU in its last 10 home games, showcasing their strength at Comerica Park.

SD vs. DET
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: G. Torres over 6 Fantasy Score.

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San Diego vs Detroit Prediction & Odds:
Free MLB Betting Insights for 4/23/25

The series finale between the San Diego Padres and Detroit Tigers on April 23, 2025, at Comerica Park sets the stage for an intriguing clash between two teams that have gotten off to strong starts this season and are quietly emerging as contenders in their respective leagues. The Padres, currently sitting at 16-7, have been one of the National League’s most consistent teams through the first month, showing a well-balanced combination of timely hitting and dependable pitching. While they’ve leaned heavily on their bullpen and top-of-the-order production, they’ve also demonstrated the ability to grind out low-scoring wins and manufacture offense late in games. The Tigers, meanwhile, are 14-9 and have been excellent at home with an 8-2 record at Comerica Park, using a scrappy, disciplined approach to frustrate opponents. For this series finale, the Padres will send left-hander Kyle Hart to the mound, who enters with a 2-1 record and a 6.48 ERA. Hart has had a turbulent start to his season, showing flashes of effectiveness but often struggling with command and allowing early-inning traffic. The Tigers will counter with right-hander Reese Olson, who’s been more consistent with a 2-1 record and a 4.50 ERA, showcasing a strong changeup and a knack for avoiding the big inning. Both pitchers face lineups capable of putting up crooked numbers, with San Diego’s offense featuring experienced bats like Fernando Tatis Jr. and Manny Machado, while Detroit’s lineup has relied on collective contributions from rising stars and solid veteran presence.

One of the key battles in this game will be how well Hart can neutralize Detroit’s right-handed-heavy lineup, and whether Olson can keep San Diego’s top hitters off balance. Defensively, both teams have been fundamentally sound, with the Padres turning key double plays in late-game situations and the Tigers flashing some excellent glove work in the infield. The bullpens will also play a vital role—San Diego’s relief corps has been a strength, closing out tight games with high-leverage precision, while Detroit’s relievers have quietly been one of the more underrated units in the league. The game also presents an interesting contrast in styles: San Diego tends to attack early in counts and look for power opportunities, while Detroit has shown more patience, working counts and generating offense with situational hitting. With both teams eyeing a series victory to build momentum heading into the weekend, execution will be paramount—especially on the mound, where early control and pitch economy could determine which side seizes the edge. Given the Tigers’ strong recent home form and the Padres’ consistent all-around performance, this finale promises to be competitive, closely contested, and potentially decided by a single miscue or clutch hit. Whether it’s Hart finding his rhythm or Olson outdueling the Padres’ sluggers, this game will be a valuable measuring stick for both teams as they aim to turn strong starts into sustained success deeper into the season.

San Diego Padres MLB Preview

The San Diego Padres enter the final game of their series against the Detroit Tigers looking to secure a series win and continue their early-season surge that has positioned them among the National League’s top-tier teams. At 16-7, the Padres have leaned on a balanced mix of explosive offense and timely pitching to fuel their success, with their lineup consistently putting pressure on opposing starters and their bullpen locking down late-game leads. Manager Mike Shildt has effectively navigated his rotation through some injury absences, and the team’s depth has been a critical factor in their ability to keep winning. The spotlight for this matchup will be on left-hander Kyle Hart, who brings a 2-1 record and a 6.48 ERA into Wednesday’s game. Hart has shown moments of competence and the ability to miss bats but has struggled with consistency, particularly in the first few innings of his starts. If he’s able to avoid giving up early runs and navigate the top half of Detroit’s lineup—especially their right-handed bats—he could give the Padres the length they need before turning the ball over to their effective bullpen. Offensively, San Diego has been carried by a lineup that includes veterans like Manny Machado, Fernando Tatis Jr., and Xander Bogaerts, all of whom bring a combination of power and plate discipline. Their ability to generate runs in a variety of ways—home runs, stolen bases, and clutch two-out hits—makes them especially dangerous on the road. The Padres have also benefitted from unexpected contributions deeper in the lineup, with players like Ha-Seong Kim and Jake Cronenworth coming through in key spots to extend innings or flip the batting order.

With Comerica Park being a more pitcher-friendly ballpark, San Diego’s approach will likely center on grinding out at-bats, using their speed to create pressure, and avoiding hitting into Detroit’s strong infield defense. Defensively, the Padres have been solid, if not spectacular, with their middle infield and outfield positioning helping them limit big innings. Perhaps their biggest strength has been their bullpen, with Robert Suarez and Wandy Peralta emerging as dominant late-inning options who consistently shut the door when holding a lead. The team is also 8-2 in its last 10 games and has been strong against the spread, particularly when scoring early and forcing opponents to play from behind. Against a Tigers team that has played very well at home, the Padres will need to strike quickly, support Hart with early offense, and then lean on their relief corps to carry them through the later innings. A win on Wednesday would not only mark another series victory but reinforce the narrative that San Diego is built for sustained success and well-equipped to handle adversity on the road. With every game important in a tight NL West race, this matchup represents another chance for the Padres to showcase their depth, focus, and competitive edge as they look to stay among baseball’s elite in the first month of the 2025 campaign.

The San Diego Padres (16-7) and Detroit Tigers (14-9) conclude their three-game series at Comerica Park on April 23, 2025, with first pitch scheduled for 1:10 p.m. ET. The Padres aim to secure a series win, while the Tigers look to defend their strong home record. San Diego vs Detroit AI Prediction: Free MLB Betting Insights for Apr 23. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Detroit Tigers MLB Preview

The Detroit Tigers return to Comerica Park for the series finale against the red-hot San Diego Padres with a chance to once again demonstrate why they’ve become one of the more quietly dangerous teams in the American League. At 14-9 on the season and 8-2 at home, Detroit has used a combination of pitching depth, defensive steadiness, and opportunistic offense to climb the AL Central standings and make life difficult for more heralded opponents. This current version of the Tigers, under manager A.J. Hinch, is far more than a rebuilding club—it’s a roster brimming with young talent, veteran poise, and a belief that every game is winnable when the team executes its formula. Right-hander Reese Olson will be tasked with containing a high-powered Padres lineup, and he enters this outing with a 2-1 record and a 4.50 ERA. Olson has been efficient in most of his starts, working deep into games and using a tight slider and low-90s fastball to induce weak contact and limit big innings. He’ll need to be particularly sharp against the heart of San Diego’s order, which includes sluggers like Manny Machado and Fernando Tatis Jr., who can change a game with one swing. Detroit’s bullpen has been a pleasant surprise this season, showing an ability to protect slim leads and deliver in high-leverage moments thanks to the steady arms of Jason Foley, Will Vest, and closer Alex Lange.

Offensively, the Tigers have adopted a team-oriented approach, with a lineup that might lack a traditional superstar but makes up for it with depth and clutch hitting. Spencer Torkelson and Riley Greene have started to find their rhythm, combining power with plate discipline, while Kerry Carpenter and Colt Keith have provided timely hits to extend innings and keep pressure on opposing pitchers. Detroit’s offensive strategy isn’t centered around the long ball—instead, it’s built on working counts, taking extra bases, and hitting behind runners, which has proven effective in games where they stay close into the middle innings. At home, the Tigers seem particularly adept at playing clean, focused baseball—limiting errors, running the bases well, and responding to pressure with situational awareness. Comerica Park, with its deep outfield gaps and pitcher-friendly dimensions, suits their defensive strengths and puts added pressure on visiting teams to execute cleanly, which bodes well in a matchup against a potent but occasionally strikeout-prone Padres offense. A series win over San Diego would not only validate Detroit’s impressive start to the season but also send a message to the rest of the league that the Tigers are not simply overachieving—they’re maturing, adapting, and building the kind of momentum that could carry them deep into the summer. If Olson can set the tone and the lineup can scrape together timely offense, Detroit has every reason to believe they can come away with another home win and continue to cement themselves as one of the American League’s most intriguing early stories in 2025.

San Diego vs. Detroit Prop Picks (AI)

Remi is pouring through loads of data on each player. In fact, anytime the Padres and Tigers play there’s always several intriguing trends to key in on. Not to mention games played at Comerica Park in Apr seemingly never follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: G. Torres over 6 Fantasy Score.

San Diego vs. Detroit Prediction (AI)

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Remi, our AI sports wizard, has been pouring over tons of data from every simulation between the Padres and Tigers and using recursive machine learning and cutting-edge AI to examine the data to a single cover probability.

Oddly enough, we’ve seen the AI has been most keyed in on the trending emphasis human bettors tend to put on San Diego’s strength factors between a Padres team going up against a possibly deflated Tigers team. Trends look to say the true game analytics appear to reflect a slight lean against one Vegas line in particular.

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Below is our current AI San Diego vs Detroit picks, computer picks Padres vs Tigers, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
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Padres Betting Trends

The Padres have covered the run line in 8 of their last 10 games, demonstrating strong performance against the spread. However, they are 2-4 ATS in their last 6 games when playing on the road against Detroit.

Tigers Betting Trends

The Tigers are 9-4 ATS in their last 13 games and have covered the spread in 6 of their last 7 home games. They are also 4-2 ATS in their last 6 games when playing at home against San Diego.

Padres vs. Tigers Matchup Trends

The total has gone UNDER in 4 of San Diego’s last 5 games, indicating a trend toward low-scoring contests. Additionally, Detroit is 8-2 SU in its last 10 home games, showcasing their strength at Comerica Park.

San Diego vs. Detroit Game Info

San Diego vs Detroit starts on April 23, 2025 at 1:10 PM EST.

Spread: Detroit -1.5
Moneyline: San Diego +135, Detroit -160
Over/Under: 8.5

San Diego: (17-7)  |  Detroit: (14-10)

Remi's searched hard and found the best prop for this matchup: G. Torres over 6 Fantasy Score.. Prices move—always shop for the best number.

The total has gone UNDER in 4 of San Diego’s last 5 games, indicating a trend toward low-scoring contests. Additionally, Detroit is 8-2 SU in its last 10 home games, showcasing their strength at Comerica Park.

SD trend: The Padres have covered the run line in 8 of their last 10 games, demonstrating strong performance against the spread. However, they are 2-4 ATS in their last 6 games when playing on the road against Detroit.

DET trend: The Tigers are 9-4 ATS in their last 13 games and have covered the spread in 6 of their last 7 home games. They are also 4-2 ATS in their last 6 games when playing at home against San Diego.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

San Diego vs. Detroit Odds

AI algorithm Remi is pouring through tons of stats on each line. In fact, anytime the San Diego vs Detroit trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme hostile environments can often follow normal, predictable patterns.

San Diego vs Detroit Opening Odds

SD Moneyline: +135
DET Moneyline: -160
SD Spread: +1.5
DET Spread: -1.5
Over/Under: 8.5

San Diego vs Detroit Live Odds

Games PTS ML SPR O/U
Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
Orioles
Yankees
+196
-240
+1.5 (-105)
-1.5 (-115)
O 9 (-105)
U 9 (-115)
Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
 
-178
 
-1.5 (+115)
O 9.5 (+100)
U 9.5 (-120)
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
+135
-160
+1.5 (-155)
-1.5 (+130)
O 8.5 (-105)
U 8.5 (-115)
Sep 27, 2025 4:05PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:05PM
White Sox
Nationals
+100
-120
+1.5 (-205)
-1.5 (+170)
O 8.5 (-115)
U 8.5 (-105)
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
+196
-240
+1.5 (-110)
-1.5 (-110)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
-130
+110
-1.5 (+130)
+1.5 (-155)
O 8 (-115)
U 8 (-105)
Sep 27, 2025 4:11PM EDT
Detroit Tigers
Boston Red Sox
9/27/25 4:11PM
Tigers
Red Sox
+110
-130
+1.5 (-190)
-1.5 (+158)
O 9 (+100)
U 9 (-120)
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
+175
-210
+1.5 (-120)
-1.5 (+100)
O 8.5 (-115)
U 8.5 (-105)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+115
-135
+1.5 (-190)
-1.5 (+158)
O 7.5 (-120)
U 7.5 (+100)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+150
-178
+1.5 (-145)
-1.5 (+122)
O 8 (-110)
U 8 (-110)
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
+122
-145
+1.5 (-190)
-1.5 (+158)
O 7 (-120)
U 7 (+100)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+118
-140
+1.5 (-190)
-1.5 (+158)
O 7.5 (-115)
U 7.5 (-105)
Sep 27, 2025 9:39PM EDT
Houston Astros
Los Angeles Angels
9/27/25 9:39PM
Astros
Angels
-140
+118
-1.5 (+115)
+1.5 (-135)
O 9 (-110)
U 9 (-110)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+100
-120
+1.5 (-220)
-1.5 (+180)
O 7 (-120)
U 7 (+100)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
+100
-120
+1.5 (-195)
-1.5 (+162)
O 10 (-115)
U 10 (-105)

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We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers San Diego Padres vs. Detroit Tigers on April 23, 2025 at Comerica Park.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
ARI@SD SD -131 57.3% 4 WIN
DET@BOS BOS -115 56.4% 5 WIN
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS