Padres vs. Tigers
Prediction, Odds & Props
Apr 23 | MLB AI Picks
Updated: 2025-04-21T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The San Diego Padres (16-7) and Detroit Tigers (14-9) conclude their three-game series at Comerica Park on April 23, 2025, with first pitch scheduled for 1:10 p.m. ET. The Padres aim to secure a series win, while the Tigers look to defend their strong home record.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Apr 23, 2025
Start Time: 1:10 PM EST
Venue: Comerica Park
Tigers Record: (14-10)
Padres Record: (17-7)
OPENING ODDS
SD Moneyline: +135
DET Moneyline: -160
SD Spread: +1.5
DET Spread: -1.5
Over/Under: 8.5
SD
Betting Trends
- The Padres have covered the run line in 8 of their last 10 games, demonstrating strong performance against the spread. However, they are 2-4 ATS in their last 6 games when playing on the road against Detroit.
DET
Betting Trends
- The Tigers are 9-4 ATS in their last 13 games and have covered the spread in 6 of their last 7 home games. They are also 4-2 ATS in their last 6 games when playing at home against San Diego.
MATCHUP TRENDS
- The total has gone UNDER in 4 of San Diego’s last 5 games, indicating a trend toward low-scoring contests. Additionally, Detroit is 8-2 SU in its last 10 home games, showcasing their strength at Comerica Park.
SD vs. DET
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: G. Torres over 6 Fantasy Score.
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San Diego vs Detroit Prediction & Odds:
Free MLB Betting Insights for 4/23/25
One of the key battles in this game will be how well Hart can neutralize Detroit’s right-handed-heavy lineup, and whether Olson can keep San Diego’s top hitters off balance. Defensively, both teams have been fundamentally sound, with the Padres turning key double plays in late-game situations and the Tigers flashing some excellent glove work in the infield. The bullpens will also play a vital role—San Diego’s relief corps has been a strength, closing out tight games with high-leverage precision, while Detroit’s relievers have quietly been one of the more underrated units in the league. The game also presents an interesting contrast in styles: San Diego tends to attack early in counts and look for power opportunities, while Detroit has shown more patience, working counts and generating offense with situational hitting. With both teams eyeing a series victory to build momentum heading into the weekend, execution will be paramount—especially on the mound, where early control and pitch economy could determine which side seizes the edge. Given the Tigers’ strong recent home form and the Padres’ consistent all-around performance, this finale promises to be competitive, closely contested, and potentially decided by a single miscue or clutch hit. Whether it’s Hart finding his rhythm or Olson outdueling the Padres’ sluggers, this game will be a valuable measuring stick for both teams as they aim to turn strong starts into sustained success deeper into the season.
Tamed the Tigers. pic.twitter.com/Jp8kblVDdZ
— San Diego Padres (@Padres) April 23, 2025
San Diego Padres MLB Preview
The San Diego Padres enter the final game of their series against the Detroit Tigers looking to secure a series win and continue their early-season surge that has positioned them among the National League’s top-tier teams. At 16-7, the Padres have leaned on a balanced mix of explosive offense and timely pitching to fuel their success, with their lineup consistently putting pressure on opposing starters and their bullpen locking down late-game leads. Manager Mike Shildt has effectively navigated his rotation through some injury absences, and the team’s depth has been a critical factor in their ability to keep winning. The spotlight for this matchup will be on left-hander Kyle Hart, who brings a 2-1 record and a 6.48 ERA into Wednesday’s game. Hart has shown moments of competence and the ability to miss bats but has struggled with consistency, particularly in the first few innings of his starts. If he’s able to avoid giving up early runs and navigate the top half of Detroit’s lineup—especially their right-handed bats—he could give the Padres the length they need before turning the ball over to their effective bullpen. Offensively, San Diego has been carried by a lineup that includes veterans like Manny Machado, Fernando Tatis Jr., and Xander Bogaerts, all of whom bring a combination of power and plate discipline. Their ability to generate runs in a variety of ways—home runs, stolen bases, and clutch two-out hits—makes them especially dangerous on the road. The Padres have also benefitted from unexpected contributions deeper in the lineup, with players like Ha-Seong Kim and Jake Cronenworth coming through in key spots to extend innings or flip the batting order.
With Comerica Park being a more pitcher-friendly ballpark, San Diego’s approach will likely center on grinding out at-bats, using their speed to create pressure, and avoiding hitting into Detroit’s strong infield defense. Defensively, the Padres have been solid, if not spectacular, with their middle infield and outfield positioning helping them limit big innings. Perhaps their biggest strength has been their bullpen, with Robert Suarez and Wandy Peralta emerging as dominant late-inning options who consistently shut the door when holding a lead. The team is also 8-2 in its last 10 games and has been strong against the spread, particularly when scoring early and forcing opponents to play from behind. Against a Tigers team that has played very well at home, the Padres will need to strike quickly, support Hart with early offense, and then lean on their relief corps to carry them through the later innings. A win on Wednesday would not only mark another series victory but reinforce the narrative that San Diego is built for sustained success and well-equipped to handle adversity on the road. With every game important in a tight NL West race, this matchup represents another chance for the Padres to showcase their depth, focus, and competitive edge as they look to stay among baseball’s elite in the first month of the 2025 campaign.

Credit: USA TODAY/IMAGN
Detroit Tigers MLB Preview
The Detroit Tigers return to Comerica Park for the series finale against the red-hot San Diego Padres with a chance to once again demonstrate why they’ve become one of the more quietly dangerous teams in the American League. At 14-9 on the season and 8-2 at home, Detroit has used a combination of pitching depth, defensive steadiness, and opportunistic offense to climb the AL Central standings and make life difficult for more heralded opponents. This current version of the Tigers, under manager A.J. Hinch, is far more than a rebuilding club—it’s a roster brimming with young talent, veteran poise, and a belief that every game is winnable when the team executes its formula. Right-hander Reese Olson will be tasked with containing a high-powered Padres lineup, and he enters this outing with a 2-1 record and a 4.50 ERA. Olson has been efficient in most of his starts, working deep into games and using a tight slider and low-90s fastball to induce weak contact and limit big innings. He’ll need to be particularly sharp against the heart of San Diego’s order, which includes sluggers like Manny Machado and Fernando Tatis Jr., who can change a game with one swing. Detroit’s bullpen has been a pleasant surprise this season, showing an ability to protect slim leads and deliver in high-leverage moments thanks to the steady arms of Jason Foley, Will Vest, and closer Alex Lange.
Offensively, the Tigers have adopted a team-oriented approach, with a lineup that might lack a traditional superstar but makes up for it with depth and clutch hitting. Spencer Torkelson and Riley Greene have started to find their rhythm, combining power with plate discipline, while Kerry Carpenter and Colt Keith have provided timely hits to extend innings and keep pressure on opposing pitchers. Detroit’s offensive strategy isn’t centered around the long ball—instead, it’s built on working counts, taking extra bases, and hitting behind runners, which has proven effective in games where they stay close into the middle innings. At home, the Tigers seem particularly adept at playing clean, focused baseball—limiting errors, running the bases well, and responding to pressure with situational awareness. Comerica Park, with its deep outfield gaps and pitcher-friendly dimensions, suits their defensive strengths and puts added pressure on visiting teams to execute cleanly, which bodes well in a matchup against a potent but occasionally strikeout-prone Padres offense. A series win over San Diego would not only validate Detroit’s impressive start to the season but also send a message to the rest of the league that the Tigers are not simply overachieving—they’re maturing, adapting, and building the kind of momentum that could carry them deep into the summer. If Olson can set the tone and the lineup can scrape together timely offense, Detroit has every reason to believe they can come away with another home win and continue to cement themselves as one of the American League’s most intriguing early stories in 2025.
Double play for your first Major League outs?
— Detroit Tigers (@tigers) April 23, 2025
Welcome to the bigs, Chase Lee 🔥 pic.twitter.com/6tTebVzldI
San Diego vs. Detroit Prop Picks (AI)
San Diego vs. Detroit Prediction (AI)

Remi, our AI sports wizard, has been pouring over tons of data from every simulation between the Padres and Tigers and using recursive machine learning and cutting-edge AI to examine the data to a single cover probability.
Oddly enough, we’ve seen the AI has been most keyed in on the trending emphasis human bettors tend to put on San Diego’s strength factors between a Padres team going up against a possibly deflated Tigers team. Trends look to say the true game analytics appear to reflect a slight lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.
Below is our current AI San Diego vs Detroit picks, computer picks Padres vs Tigers, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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Padres Betting Trends
The Padres have covered the run line in 8 of their last 10 games, demonstrating strong performance against the spread. However, they are 2-4 ATS in their last 6 games when playing on the road against Detroit.
Tigers Betting Trends
The Tigers are 9-4 ATS in their last 13 games and have covered the spread in 6 of their last 7 home games. They are also 4-2 ATS in their last 6 games when playing at home against San Diego.
Padres vs. Tigers Matchup Trends
The total has gone UNDER in 4 of San Diego’s last 5 games, indicating a trend toward low-scoring contests. Additionally, Detroit is 8-2 SU in its last 10 home games, showcasing their strength at Comerica Park.
San Diego vs. Detroit Game Info
What time does San Diego vs Detroit start on April 23, 2025?
San Diego vs Detroit starts on April 23, 2025 at 1:10 PM EST.
Where is San Diego vs Detroit being played?
Venue: Comerica Park.
What are the opening odds for San Diego vs Detroit?
Spread: Detroit -1.5
Moneyline: San Diego +135, Detroit -160
Over/Under: 8.5
What are the records for San Diego vs Detroit?
San Diego: (17-7) | Detroit: (14-10)
What is the AI best bet for San Diego vs Detroit?
Remi's searched hard and found the best prop for this matchup: G. Torres over 6 Fantasy Score.. Prices move—always shop for the best number.
What are San Diego vs Detroit trending bets?
The total has gone UNDER in 4 of San Diego’s last 5 games, indicating a trend toward low-scoring contests. Additionally, Detroit is 8-2 SU in its last 10 home games, showcasing their strength at Comerica Park.
What are San Diego trending bets?
SD trend: The Padres have covered the run line in 8 of their last 10 games, demonstrating strong performance against the spread. However, they are 2-4 ATS in their last 6 games when playing on the road against Detroit.
What are Detroit trending bets?
DET trend: The Tigers are 9-4 ATS in their last 13 games and have covered the spread in 6 of their last 7 home games. They are also 4-2 ATS in their last 6 games when playing at home against San Diego.
Where can I find AI Picks for San Diego vs Detroit?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
San Diego vs. Detroit Odds
AI algorithm Remi is pouring through tons of stats on each line. In fact, anytime the San Diego vs Detroit trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme hostile environments can often follow normal, predictable patterns.
San Diego vs Detroit Opening Odds
SD Moneyline:
+135 DET Moneyline: -160
SD Spread: +1.5
DET Spread: -1.5
Over/Under: 8.5
San Diego vs Detroit Live Odds
Games | PTS | ML | SPR | O/U | |
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Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
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–
–
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+196
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O 9 (-105)
U 9 (-115)
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–
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-178
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-1.5 (+115)
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O 9.5 (+100)
U 9.5 (-120)
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Sep 27, 2025 3:09PM EDT
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Toronto Blue Jays
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–
–
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+135
-160
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+1.5 (-155)
-1.5 (+130)
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O 8.5 (-105)
U 8.5 (-115)
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Sep 27, 2025 4:05PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:05PM
White Sox
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–
–
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+100
-120
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+1.5 (-205)
-1.5 (+170)
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O 8.5 (-115)
U 8.5 (-105)
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Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
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Rockies
Giants
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–
–
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+196
-240
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+1.5 (-110)
-1.5 (-110)
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O 8 (-105)
U 8 (-115)
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Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
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–
–
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-130
+110
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-1.5 (+130)
+1.5 (-155)
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O 8 (-115)
U 8 (-105)
|
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Sep 27, 2025 4:11PM EDT
Detroit Tigers
Boston Red Sox
9/27/25 4:11PM
Tigers
Red Sox
|
–
–
|
+110
-130
|
+1.5 (-190)
-1.5 (+158)
|
O 9 (+100)
U 9 (-120)
|
|
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
|
–
–
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+175
-210
|
+1.5 (-120)
-1.5 (+100)
|
O 8.5 (-115)
U 8.5 (-105)
|
|
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
|
–
–
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+115
-135
|
+1.5 (-190)
-1.5 (+158)
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O 7.5 (-120)
U 7.5 (+100)
|
|
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
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–
–
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+150
-178
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+1.5 (-145)
-1.5 (+122)
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O 8 (-110)
U 8 (-110)
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Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
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–
–
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+122
-145
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+1.5 (-190)
-1.5 (+158)
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O 7 (-120)
U 7 (+100)
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Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
|
–
–
|
+118
-140
|
+1.5 (-190)
-1.5 (+158)
|
O 7.5 (-115)
U 7.5 (-105)
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Sep 27, 2025 9:39PM EDT
Houston Astros
Los Angeles Angels
9/27/25 9:39PM
Astros
Angels
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–
–
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-140
+118
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-1.5 (+115)
+1.5 (-135)
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O 9 (-110)
U 9 (-110)
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Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
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–
–
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+100
-120
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+1.5 (-220)
-1.5 (+180)
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O 7 (-120)
U 7 (+100)
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Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
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–
–
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+100
-120
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+1.5 (-195)
-1.5 (+162)
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O 10 (-115)
U 10 (-105)
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MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers San Diego Padres vs. Detroit Tigers on April 23, 2025 at Comerica Park.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
ARI@SD | SD -131 | 57.3% | 4 | WIN |
DET@BOS | BOS -115 | 56.4% | 5 | WIN |
NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
LAA@COL | COL +108 | 50.5% | 3 | WIN |
TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
KC@PHI | PHI -130 | 58.3% | 4 | WIN |
LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
KC@CLE | KC -104 | 52.0% | 3 | WIN |
CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |
PHI@NYM | OVER 8.5 | 55.6% | 4 | LOSS |
LAA@TEX | LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS | 54.1% | 4 | LOSS |
KC@CHW | KC -109 | 54.2% | 4 | WIN |
SD@SEA | DYLAN CEASE OVER 16.5 OUTS | 53.9% | 3 | LOSS |
SD@SEA | UNDER 8.5 | 54.4% | 4 | LOSS |
MIN@TOR | JOE RYAN UNDER 2.5 EARNED RUNS | 54.1% | 4 | LOSS |
SF@MIL | MIL +100 | 54.0% | 6 | LOSS |
TOR@MIA | MIA +1.5 | 62.0% | 6 | WIN |
CHC@LAA | OVER 9.5 | 54.9% | 4 | LOSS |
BOS@NYY | CARLOS RODON UNDER 4.5 HITS ALLOWED | 54.2% | 4 | WIN |
KC@DET | DET -115 | 56.1% | 5 | WIN |
CHC@LAA | LAA +1.5 | 57.6% | 5 | LOSS |