Yankees vs Guardians Prediction — AI Finds CAN'T MISS MLB Lines & Props (Apr 23)

Updated: 2025-04-21T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The New York Yankees and Cleveland Guardians conclude their three-game series on April 23, 2025, at Progressive Field, with both teams vying for a series win. The Yankees aim to rebound from a narrow 3-2 loss in the previous game, while the Guardians look to extend their five-game winning streak.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Apr 23, 2025

Start Time: 1:10 PM EST​

Venue: Progressive Field​

Guardians Record: (14-9)

Yankees Record: (14-10)

OPENING ODDS

NYY Moneyline: -147

CLE Moneyline: +124

NYY Spread: -1.5

CLE Spread: +1.5

Over/Under: 8

NYY
Betting Trends

  • The Yankees are 6-4 against the spread (ATS) in their last 10 games, demonstrating solid performance on the road. They have covered the spread in 60% of their recent matchups, indicating a competitive edge even in away games.

CLE
Betting Trends

  • The Guardians have been formidable at home, with a 7-3 ATS record in their last 10 games at Progressive Field. Their recent home performance includes a five-game winning streak, showcasing their strength on familiar turf.

MATCHUP TRENDS

  • The total has gone UNDER in four of the last six meetings between the Yankees and Guardians, suggesting closely contested, low-scoring games. Additionally, the Yankees have covered the spread in five of their last seven games against Cleveland, highlighting their competitive play in this matchup.

NYY vs. CLE
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: P. Goldschmidt over 5.5 Fantasy Score.

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New York Yankees vs Cleveland Prediction & Odds:
Free MLB Betting Insights for 4/23/25

The final game of this three-game series between the New York Yankees and the Cleveland Guardians on April 23, 2025, at Progressive Field brings two of the American League’s most competitive teams into direct conflict as both look to secure a key early-season series win. The Yankees, sitting at 14-10, have displayed offensive power and depth despite battling injuries to major contributors such as Gerrit Cole and DJ LeMahieu. At the forefront of New York’s attack is Aaron Judge, who continues to produce at an MVP-caliber level with a blistering .384 batting average and a league-leading .698 slugging percentage. Judge’s presence in the lineup forces pitchers into defensive patterns, opening up opportunities for emerging contributors like Ben Rice and Anthony Volpe to step into key roles. While the offense has carried the load for the Yankees recently, they’ve had to manage inconsistent starting pitching, which puts extra pressure on both the bullpen and offensive output. Carlos Rodón takes the mound in this series finale, bringing a 2-3 record and 4.35 ERA. Despite occasional control issues, Rodón has been effective at missing bats, striking out 37 in 29 innings, and his dominance against left-handed hitters remains an asset. However, Rodón will need to avoid long innings and limit traffic on the bases against a contact-oriented Cleveland lineup that excels at manufacturing runs through situational hitting.

On the other side, the Cleveland Guardians enter the game on a five-game winning streak, including a tight 3-2 win in the previous game that displayed their formula for success—timely hitting, steady defense, and late-inning bullpen stability. At 14-9, Cleveland leads the AL Central and has leaned heavily on a balanced offense led by Steven Kwan, who enters the game with a .333 batting average and a .506 slugging clip. Kwan’s ability to get on base sets the table for sluggers like José Ramírez, who continues to be one of the most consistent run producers in the league with his mix of power and clutch contact. Gabriel Arias and Kyle Manzardo have emerged as reliable secondary threats, giving Cleveland quality at-bats deeper into the lineup. Luis Ortiz gets the start for the Guardians, holding a 2-2 record and a 5.48 ERA, numbers that reflect his ongoing battle with consistency. Ortiz has shown flashes of excellence but has struggled with control and keeping the ball in the park against disciplined offenses like New York’s. This game figures to hinge on two key factors: whether Rodón can silence a Guardians lineup that thrives on small-ball tactics, and whether Ortiz can limit damage early and keep the powerful Yankees from breaking the game open in the first few innings. With both teams playing high-level baseball and boasting contrasting strengths—power versus precision, aggression versus efficiency—this series finale is poised to be a closely fought contest where every baserunner, defensive play, and managerial decision could shift momentum. As the early-season standings begin to take shape, games like this are crucial for both teams in defining their respective identities and maintaining pace in their competitive divisions.

New York Yankees Yankees MLB Preview

The New York Yankees arrive at Progressive Field for the series finale against the Cleveland Guardians looking to bounce back from a narrow 3-2 loss and reclaim their early-season momentum as they continue their road trip. With a 14-10 record and leading the AL East, the Yankees have remained one of baseball’s most formidable squads despite dealing with several high-profile injuries that have tested their depth and resilience. MVP frontrunner Aaron Judge continues to anchor the offense, tearing through opposing pitching with a scorching .384 average and a slugging percentage north of .690. His discipline at the plate and ability to hit to all fields has forced opposing pitchers into cautious approaches, opening up run-scoring chances for younger players like Ben Rice and Anthony Volpe, who have stepped up admirably in recent weeks. Manager Aaron Boone has done a commendable job balancing lineup rotations and keeping the offense flowing despite losing DJ LeMahieu and still waiting on Gerrit Cole’s return to bolster the rotation. In the interim, Carlos Rodón has emerged as a vital piece of the pitching puzzle. He enters Wednesday’s game with a 2-3 record and a 4.35 ERA, with 37 strikeouts in 29 innings showcasing his swing-and-miss potential when he’s locked in. Rodón will need to maintain that sharpness and avoid falling behind in counts against a Guardians lineup that thrives on contact and capitalizes on small-ball opportunities.

The Yankees’ bullpen, featuring Clay Holmes, Wandy Peralta, and Ian Hamilton, has been steady, and will need to be ready if Rodón runs into trouble early. Defensively, the Yankees have been solid if unspectacular, though they’ve had occasional lapses that have cost them key runs in tight games. Their challenge in this finale is to jump out early, apply pressure on Guardians starter Luis Ortiz, and limit Cleveland’s ability to play with a lead—something that has allowed the Guardians to control tempo effectively throughout their five-game win streak. From a psychological standpoint, snapping that streak on Cleveland’s home turf would be a significant confidence boost, particularly as the Yankees aim to maintain their hold atop the division and keep pace with surging competitors like the Orioles and Rays. With their potent mix of veteran power, youthful spark, and a pitching staff capable of overpowering most lineups, the Yankees remain dangerous in any environment. But to win this series, they’ll need more timely hitting in scoring situations and a cleaner defensive performance than they offered in Tuesday night’s narrow defeat. The formula for victory is clear: command from Rodón, production from the top of the order, and tight execution late. If those pieces fall into place, the Yankees are well-positioned to end Cleveland’s streak and take another step forward in what they hope will be a championship-caliber campaign.

The New York Yankees and Cleveland Guardians conclude their three-game series on April 23, 2025, at Progressive Field, with both teams vying for a series win. The Yankees aim to rebound from a narrow 3-2 loss in the previous game, while the Guardians look to extend their five-game winning streak. New York Yankees vs Cleveland AI Prediction: Free MLB Betting Insights for Apr 23. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Cleveland Guardians MLB Preview

The Cleveland Guardians enter the final game of their three-game set against the New York Yankees on April 23 with momentum firmly on their side, riding a five-game winning streak and fresh off a gritty 3-2 victory that showcased their ability to out-execute even the most star-studded opponents. At 14-9, the Guardians lead the AL Central and have established themselves early in the season as one of the most well-rounded and fundamentally sound teams in baseball. Their success has not hinged on one superstar but rather on a collective identity centered on contact hitting, base running intelligence, defensive efficiency, and timely pitching. Leading the offensive charge is Steven Kwan, who continues to excel as one of the league’s most consistent table-setters, batting .333 with a .506 slugging percentage and giving Cleveland a reliable spark atop the lineup. José Ramírez remains the beating heart of the lineup—his bat speed, plate discipline, and situational awareness make him an enduring problem for opposing pitchers, and his leadership sets the tone for the younger players on the roster. Gabriel Arias and Kyle Manzardo have also added welcome offensive depth, extending innings and helping the Guardians avoid the offensive droughts that often plagued them in previous seasons. On the mound, Luis Ortiz will take the ball with the task of containing a Yankees offense powered by the red-hot Aaron Judge.

Ortiz enters with a 2-2 record and a 5.48 ERA—numbers that reflect some command struggles but also hint at his potential when his sinker-slider combo is working effectively. Ortiz’s key challenge will be getting ahead in counts and keeping the ball on the ground to avoid giving up the long ball to Judge or the supporting cast. With strong defense behind him, particularly from Andrés Giménez and Myles Straw, Ortiz can afford to pitch to contact, relying on the Guardians’ infield to turn outs efficiently. The bullpen has been a major asset in tight games, with Emmanuel Clase anchoring the closer role and reliable setup performances from Nick Sandlin and Scott Barlow helping Cleveland shut the door late. Manager Stephen Vogt has deployed his bullpen strategically and has been aggressive with his pinch-hitting and defensive substitutions, trusting his bench and maximizing matchups. Playing at home in Progressive Field, where they’ve gone 7-3 in their last 10 games, the Guardians will look to set the tone early by putting pressure on Carlos Rodón, working deep counts, and forcing him into high-leverage situations. A series win against a Yankees team leading the AL East would further validate Cleveland’s strong start and reinforce their position as legitimate contenders, not just division front-runners. With strong clubhouse chemistry, a clear game plan, and a roster playing fundamentally clean baseball, the Guardians are proving they can beat any opponent when they dictate tempo and stay true to their strengths. A win on Wednesday would not only secure the series but extend a statement win streak and send another reminder that this Cleveland team is built for both April success and the long haul.

New York Yankees vs. Cleveland Prop Picks (AI)

AI algorithm Remi is pouring through mountains of datapoints on each player. In fact, anytime the Yankees and Guardians play there’s always several intriguing observations to key in on. Not to mention games played at Progressive Field in Apr seemingly never follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: P. Goldschmidt over 5.5 Fantasy Score.

New York Yankees vs. Cleveland Prediction (AI)

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Remi, our AI sports algorithm, has been pouring over millions of data from every angle between the Yankees and Guardians and using recursive machine learning and industry leading AI to boil down the data to a single cover probability.

Oddly enough, we’ve seen the AI has been most focused on the unproportionally assigned emphasis knucklehead sportsbettors tend to put on Cleveland’s strength factors between a Yankees team going up against a possibly unhealthy Guardians team. Trends look to say the true game analytics might reflect a slight lean against one Vegas line in particular.

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Below is our current AI New York Yankees vs Cleveland picks, computer picks Yankees vs Guardians, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
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Yankees Betting Trends

The Yankees are 6-4 against the spread (ATS) in their last 10 games, demonstrating solid performance on the road. They have covered the spread in 60% of their recent matchups, indicating a competitive edge even in away games.

Guardians Betting Trends

The Guardians have been formidable at home, with a 7-3 ATS record in their last 10 games at Progressive Field. Their recent home performance includes a five-game winning streak, showcasing their strength on familiar turf.

Yankees vs. Guardians Matchup Trends

The total has gone UNDER in four of the last six meetings between the Yankees and Guardians, suggesting closely contested, low-scoring games. Additionally, the Yankees have covered the spread in five of their last seven games against Cleveland, highlighting their competitive play in this matchup.

New York Yankees vs. Cleveland Game Info

New York Yankees vs Cleveland starts on April 23, 2025 at 1:10 PM EST.

Spread: Cleveland +1.5
Moneyline: New York Yankees -147, Cleveland +124
Over/Under: 8

New York Yankees: (14-10)  |  Cleveland: (14-9)

Remi's searched hard and found the best prop for this matchup: P. Goldschmidt over 5.5 Fantasy Score.. Prices move—always shop for the best number.

The total has gone UNDER in four of the last six meetings between the Yankees and Guardians, suggesting closely contested, low-scoring games. Additionally, the Yankees have covered the spread in five of their last seven games against Cleveland, highlighting their competitive play in this matchup.

NYY trend: The Yankees are 6-4 against the spread (ATS) in their last 10 games, demonstrating solid performance on the road. They have covered the spread in 60% of their recent matchups, indicating a competitive edge even in away games.

CLE trend: The Guardians have been formidable at home, with a 7-3 ATS record in their last 10 games at Progressive Field. Their recent home performance includes a five-game winning streak, showcasing their strength on familiar turf.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

New York Yankees vs. Cleveland Odds

Remi is pouring through loads of data points on each line. In fact, anytime the New York Yankees vs Cleveland trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme travel distance almost always follow normal, predictable betting trends.

New York Yankees vs Cleveland Opening Odds

NYY Moneyline: -147
CLE Moneyline: +124
NYY Spread: -1.5
CLE Spread: +1.5
Over/Under: 8

New York Yankees vs Cleveland Live Odds

Games PTS ML SPR O/U

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Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers New York Yankees Yankees vs. Cleveland Guardians on April 23, 2025 at Progressive Field.
Odds shown reflect widely available numbers and may update closer to kickoff.

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    LEAN     %WIN     UNITS RESULT
LAD@TOR TOR +1.5 56.7% 2 WIN
TOR@LAD TOR +1.5 55.3% 4 WIN
TOR@SEA OVER 7 54.9% 3 WIN
LAD@MIL UNDER 7.5 56.6% 6 WIN
TOR@NYY OVER 8 54.9% 4 WIN
TOR@NYY CARLOS RODON OVER 1.5 TOTAL WALKS ALLOWED 53.3% 3 WIN
NYY@TOR OVER 7.5 54.8% 2 WIN
LAD@PHI OVER 7 53.8% 3 WIN
SD@CHC CHC -109 53.8% 3 WIN
SD@CHC OVER 7.5 54.5% 4 LOSS
SD@CHC CHC -111 54.8% 4 LOSS
CIN@LAD SHOHEI OHTANI OVER 1.5 BASES 53.5% 3 WIN
BOS@NYY OVER 7 53.8% 3 LOSS
CIN@LAD ELLY DE LA CRUZ OVER 0.5 BASES 54.4% 4 LOSS
ARI@SD SD -131 57.3% 4 WIN
DET@BOS BOS -115 56.4% 5 WIN
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN