Orioles vs. Nationals
Prediction, Odds & Props
Apr 23 | MLB AI Picks
Updated: 2025-04-21T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Baltimore Orioles and Washington Nationals face off on April 23, 2025, at Nationals Park, concluding their interleague series. Both teams are looking to secure a series win and gain momentum in their respective divisions.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Apr 23, 2025
Start Time: 6:45 PM EST​
Venue: Nationals Park​
Nationals Record: (10-13)
Orioles Record: (9-13)
OPENING ODDS
BAL Moneyline: -134
WAS Moneyline: +113
BAL Spread: -1.5
WAS Spread: +1.5
Over/Under: 9.5
BAL
Betting Trends
- The Orioles have covered the run line in 6 of their last 10 games, showcasing a strong performance against the spread recently.
WAS
Betting Trends
- The Nationals have covered the run line in 4 of their last 10 home games, indicating inconsistent performance against the spread at Nationals Park.
MATCHUP TRENDS
- In the last 6 meetings between the Orioles and Nationals, the total has gone OVER 4 times, suggesting a trend toward high-scoring games in this matchup.
BAL vs. WAS
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: R. O'Hearn over 1.5 Hits+Runs+RBI.
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Baltimore vs Washington Prediction & Odds:
Free MLB Betting Insights for 4/23/25
The total has gone over in four of the last six meetings between these clubs, a trend fueled by both teams’ ability to generate runs and their susceptibility to lapses on the mound. This sets up a potentially high-scoring finale unless one of the starting pitchers can establish early dominance and avoid giving up free passes, which have haunted both staffs in this series. The Orioles’ approach at the plate—aggressive but selective—has proven especially effective in these interleague games, and they’ll look to maintain that pressure from the first pitch, likely pushing the Nationals’ bullpen into action by the middle innings. For Washington, the game plan likely revolves around manufacturing runs early and hoping for a shutdown performance from their starter to keep Baltimore’s power bats at bay. Defensively, the Nationals must clean up the mental mistakes that have extended innings and allowed Baltimore to put up big numbers. The Orioles, by contrast, have been more composed and precise, especially when protecting narrow leads in late innings. With both teams hungry for a series win—Baltimore to extend its lead in a tough AL East, and Washington to prove its youth movement can hang with postseason-caliber squads—this game has the potential to swing on one big inning, one bullpen decision, or one defensive miscue. Fans can expect a high-energy matchup defined by contrasting identities: a polished, playoff-minded Orioles club looking to close strong and a gritty Nationals team eager to prove they’re building something real. The result may ultimately come down to which side executes better under pressure, and which lineup delivers when the game’s biggest moments arrive.
Game 1 in The District. pic.twitter.com/XmScfmRucH
— Baltimore Orioles (@Orioles) April 22, 2025
Baltimore Orioles MLB Preview
The Baltimore Orioles head into the final game of their interleague series against the Washington Nationals with growing momentum and the kind of balanced, high-octane identity that has defined their early-season success in 2025. At 14–8 and consistently performing well against the spread—covering in six of their last ten—they’ve emerged as one of the most formidable road teams in the American League, blending explosive offense with sound fundamentals and a bullpen that has proven itself capable of holding leads against a wide range of opponents. Central to Baltimore’s current surge is the bat of Gunnar Henderson, who has quickly become the spark plug at the top of the order with a mature plate approach, gap-to-gap power, and an ability to set the tone in the first inning. Behind him, Adley Rutschman continues to anchor the lineup, not just with his bat but with his presence behind the plate, guiding a young but effective pitching staff and calling games with the poise of a seasoned veteran. The middle of the order—featuring sluggers like Anthony Santander, Ryan Mountcastle, and Jordan Westburg—has given the Orioles a feared run-producing engine that can punish mistakes and work counts deep, often forcing opposing starters out early and setting up favorable matchups late. Speed and baserunning IQ further diversify their attack, with Cedric Mullins leading the way on the basepaths and generating pressure on defenses from the nine-hole or top of the order depending on the day.
On the mound, the Orioles have leaned on solid, if unspectacular, starting pitching to get through the early innings and bridge the game to a bullpen that ranks among the league’s best in strikeout rate and ERA. Yennier Cano has been electric in the late innings, pairing with lefty Danny Coulombe and a cast of matchup-specific arms that have thrived in Hyde’s aggressive bullpen deployment. Though their starters may not lead the league in velocity or strikeouts, their ability to limit walks, manage pitch counts, and avoid big innings has kept Baltimore in almost every game they’ve played, which is why they’ve consistently covered the spread even in tough environments. Defensively, Baltimore has shown marked improvement over last season, with Henderson and Jorge Mateo forming a reliable infield tandem and outfielders like Mullins and Austin Hays providing range and sure hands in the gaps. The Orioles’ current road trip has reinforced their identity as a team that not only travels well but thrives in interleague matchups thanks to their depth, lineup flexibility, and a fundamentally sound approach that emphasizes run prevention as much as run production. Against a Nationals team still finding its rhythm, the Orioles are positioned well to exploit inconsistencies in Washington’s rotation and bullpen, especially if they can get on the board early and dictate the pace of the game. A win would not only secure the series but also serve as another benchmark in a season where Baltimore’s ceiling appears to be rising with every passing week, signaling to the rest of the American League that this is not just a playoff-caliber squad—it’s a club with championship ambitions, executing daily with purpose, poise, and a clear plan to stay atop the standings.

Credit: USA TODAY/IMAGN
Washington Nationals MLB Preview
The Washington Nationals enter the final game of their interleague series against the Baltimore Orioles at Nationals Park with the hope of salvaging a win and regaining some consistency as they continue to define their identity in the early stretch of the 2025 season. While sitting near the .500 mark with an 11–12 record, the Nationals have shown moments of competitiveness, especially with their offense, but have struggled to maintain momentum at home, covering the run line in only four of their last ten games at Nationals Park. Their performance against Baltimore has also been uneven, and the total has gone over in four of the last six meetings between these two teams—highlighting both the potential for offense and the challenges Washington has faced in run prevention. Leading the offensive charge for the Nationals is CJ Abrams, whose speed, athleticism, and emerging bat-to-ball skills have given Washington a consistent presence at the top of the order. Alongside Abrams, Joey Meneses has offered middle-of-the-order power, though the Nationals have yet to see sustained production from the full lineup. Players like Keibert Ruiz and Lane Thomas have had their moments, but timely hitting remains a problem, especially with runners in scoring position where missed opportunities have defined several losses this season. The Nationals are not built around the long ball, and instead rely on situational execution, contact hitting, and small ball tactics—an approach that can work well when they play clean and efficient baseball, but one that is vulnerable against power-heavy lineups like Baltimore’s if they fall behind early. On the mound, Washington’s starting pitching has been one of their most unpredictable components.
The rotation has shown flashes of potential, particularly from young arms like MacKenzie Gore and Josiah Gray, but inconsistency in command and difficulty navigating lineups the second and third time through has put pressure on a bullpen that has already logged a heavy workload. The relief corps, featuring Hunter Harvey and Kyle Finnegan in late innings, has had some bright moments, but overall lacks the depth or shutdown capability needed to consistently protect one- or two-run leads, especially when overexposed. Defensively, the Nationals have played a fairly clean brand of baseball, with Abrams continuing to develop into a reliable shortstop and outfielders like Victor Robles and Lane Thomas providing above-average coverage and arms. Still, the margin for error is thin for this team, and unforced mistakes—whether it’s a missed cutoff, an errant throw, or a failed bunt attempt—have often been the difference between competitive games and late-inning losses. Manager Dave Martinez has done his best to manage a roster still in transition, balancing development with competitiveness, but against a team like Baltimore that applies constant pressure, Washington must be perfect in execution, opportunistic with runners on base, and stingy with free passes. If the Nationals can get a solid outing from their starter, avoid multi-run innings early, and find just enough timely offense, they have a shot to level the series and take a much-needed confidence boost into their next homestand. But anything short of sharp execution across all phases will likely result in another frustrating close loss, emblematic of a team still learning how to close the gap between flashes of promise and sustained success.
CREWS SHIPPED pic.twitter.com/PqtbeMOVYJ
— Washington Nationals (@Nationals) April 23, 2025
Baltimore vs. Washington Prop Picks (AI)
Baltimore vs. Washington Prediction (AI)

Remi, our AI sports algorithm, has been pouring over tons of data from every facet between the Orioles and Nationals and using recursive machine learning and industry leading AI to analyze the data to a single cover probability.
The Algorithm has been most watching on the growing weight emotional bettors tend to put on Baltimore’s strength factors between a Orioles team going up against a possibly healthy Nationals team. It appears the true game analytics appear to reflect a slight lean against one Vegas line specifically.
Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.
Below is our current AI Baltimore vs Washington picks, computer picks Orioles vs Nationals, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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MLB | 9/26 | DET@BOS | UNLOCK THIS PICK | 5 |
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MLB | 9/26 | BAL@NYY | UNLOCK THIS PICK | 4 |
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MLB | 9/26 | ARI@SD | UNLOCK THIS PICK | 4 |
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MLB | 9/26 | NYM@MIA | UNLOCK THIS PICK | 1 |
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MLB | 9/26 | NYM@MIA | GET FREE PICK NOW | 1 | – | |
MLB | 9/26 | COL@SF | UNLOCK THIS PICK | 0 |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.
Orioles Betting Trends
The Orioles have covered the run line in 6 of their last 10 games, showcasing a strong performance against the spread recently.
Nationals Betting Trends
The Nationals have covered the run line in 4 of their last 10 home games, indicating inconsistent performance against the spread at Nationals Park.
Orioles vs. Nationals Matchup Trends
In the last 6 meetings between the Orioles and Nationals, the total has gone OVER 4 times, suggesting a trend toward high-scoring games in this matchup.
Baltimore vs. Washington Game Info
What time does Baltimore vs Washington start on April 23, 2025?
Baltimore vs Washington starts on April 23, 2025 at 6:45 PM EST.
Where is Baltimore vs Washington being played?
Venue: Nationals Park.
What are the opening odds for Baltimore vs Washington?
Spread: Washington +1.5
Moneyline: Baltimore -134, Washington +113
Over/Under: 9.5
What are the records for Baltimore vs Washington?
Baltimore: (9-13) Â |Â Washington: (10-13)
What is the AI best bet for Baltimore vs Washington?
Remi's searched hard and found the best prop for this matchup: R. O'Hearn over 1.5 Hits+Runs+RBI.. Prices move—always shop for the best number.
What are Baltimore vs Washington trending bets?
In the last 6 meetings between the Orioles and Nationals, the total has gone OVER 4 times, suggesting a trend toward high-scoring games in this matchup.
What are Baltimore trending bets?
BAL trend: The Orioles have covered the run line in 6 of their last 10 games, showcasing a strong performance against the spread recently.
What are Washington trending bets?
WAS trend: The Nationals have covered the run line in 4 of their last 10 home games, indicating inconsistent performance against the spread at Nationals Park.
Where can I find AI Picks for Baltimore vs Washington?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
Baltimore vs. Washington Odds
Remi is pouring through loads of data on each player. In fact, anytime the Baltimore vs Washington trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme travel distance rarely follow normal, predictable patterns.
Baltimore vs Washington Opening Odds
BAL Moneyline:
-134 WAS Moneyline: +113
BAL Spread: -1.5
WAS Spread: +1.5
Over/Under: 9.5
Baltimore vs Washington Live Odds
Games | PTS | ML | SPR | O/U | |
---|---|---|---|---|---|
Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
Orioles
Yankees
|
–
–
|
+190
-235
|
+1.5 (-110)
-1.5 (-110)
|
O 8.5 (-120)
U 8.5 (+100)
|
|
Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
|
–
–
|
-180
|
-1.5 (+115)
|
O 9.5 (-105)
U 9.5 (-115)
|
|
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
|
–
–
|
+130
-155
|
+1.5 (-155)
-1.5 (+130)
|
O 8.5 (-110)
U 8.5 (-110)
|
|
Sep 27, 2025 4:06PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:06PM
White Sox
Nationals
|
–
–
|
+100
-120
|
-1.5 (+165)
+1.5 (-200)
|
O 8.5 (-110)
U 8.5 (-110)
|
|
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
|
–
–
|
+185
-225
|
+1.5 (-110)
-1.5 (-110)
|
O 8 (-105)
U 8 (-115)
|
|
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
|
–
–
|
-130
+110
|
-1.5 (+125)
+1.5 (-150)
|
O 8 (-115)
U 8 (-105)
|
|
Sep 27, 2025 4:11PM EDT
Detroit Tigers
Boston Red Sox
9/27/25 4:11PM
Tigers
Red Sox
|
–
–
|
+125
-150
|
+1.5 (-180)
-1.5 (+150)
|
O 9 (+100)
U 9 (-120)
|
|
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
|
–
–
|
+170
-205
|
+1.5 (-120)
-1.5 (+100)
|
O 8.5 (-115)
U 8.5 (-105)
|
|
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
|
–
–
|
+125
-150
|
+1.5 (-180)
-1.5 (+150)
|
O 8 (-105)
U 8 (-115)
|
|
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
|
–
–
|
+145
-175
|
+1.5 (-155)
-1.5 (+130)
|
O 8 (-110)
U 8 (-110)
|
|
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
|
–
–
|
+135
-165
|
+1.5 (-180)
-1.5 (+150)
|
O 7 (-120)
U 7 (+100)
|
|
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
|
–
–
|
+115
-140
|
+1.5 (-195)
-1.5 (+160)
|
O 7.5 (-120)
U 7.5 (+100)
|
|
Sep 27, 2025 9:39PM EDT
Houston Astros
Los Angeles Angels
9/27/25 9:39PM
Astros
Angels
|
–
–
|
-165
+135
|
-1.5 (+105)
+1.5 (-125)
|
O 9 (+100)
U 9 (-120)
|
|
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
|
–
–
|
+105
-125
|
+1.5 (-205)
-1.5 (+170)
|
O 7.5 (+105)
U 7.5 (-125)
|
|
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
|
–
–
|
+100
-120
|
-1.5 (+150)
+1.5 (-180)
|
O 10 (-110)
U 10 (-110)
|
MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Baltimore Orioles vs. Washington Nationals on April 23, 2025 at Nationals Park.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
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   LEAN |    %WIN |    UNITS | RESULT |
---|---|---|---|---|
NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
LAA@COL | COL +108 | 50.5% | 3 | WIN |
TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
KC@PHI | PHI -130 | 58.3% | 4 | WIN |
LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
KC@CLE | KC -104 | 52.0% | 3 | WIN |
CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |
PHI@NYM | OVER 8.5 | 55.6% | 4 | LOSS |
LAA@TEX | LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS | 54.1% | 4 | LOSS |
KC@CHW | KC -109 | 54.2% | 4 | WIN |
SD@SEA | DYLAN CEASE OVER 16.5 OUTS | 53.9% | 3 | LOSS |
SD@SEA | UNDER 8.5 | 54.4% | 4 | LOSS |
MIN@TOR | JOE RYAN UNDER 2.5 EARNED RUNS | 54.1% | 4 | LOSS |
SF@MIL | MIL +100 | 54.0% | 6 | LOSS |
TOR@MIA | MIA +1.5 | 62.0% | 6 | WIN |
CHC@LAA | OVER 9.5 | 54.9% | 4 | LOSS |
BOS@NYY | CARLOS RODON UNDER 4.5 HITS ALLOWED | 54.2% | 4 | WIN |
KC@DET | DET -115 | 56.1% | 5 | WIN |
CHC@LAA | LAA +1.5 | 57.6% | 5 | LOSS |
CIN@ARI | KEBRYAN HAYES STRIKEOUTS UNDER 0.5 | 56.2% | 6 | WIN |
LAD@SD | SD +110 | 50.9% | 6 | WIN |