Guardians vs. Pirates
Prediction, Odds & Props
Apr 18 | MLB AI Picks

Updated: 2025-04-16T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Cleveland Guardians (8–7) visit the Pittsburgh Pirates (5–9) at PNC Park on April 18, 2025, in an interleague matchup between two teams aiming to build momentum early in the season. First pitch is scheduled for 6:35 p.m. ET.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Apr 18, 2025

Start Time: 6:40 PM EST​

Venue: PNC Park​

Pirates Record: (8-12)

Guardians Record: (9-9)

OPENING ODDS

CLE Moneyline: -134

PIT Moneyline: +113

CLE Spread: -1.5

PIT Spread: +1.5

Over/Under: 9

CLE
Betting Trends

  • The Guardians have a 3–2 record against the spread (ATS) in their last five games.

PIT
Betting Trends

  • The Pirates are 2–3 ATS in their last five home games.

MATCHUP TRENDS

  • In their last 10 head-to-head matchups, the Guardians have a 6–4 record against the Pirates, with the over hitting in 6 of those games.

CLE vs. PIT
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: J. Bart over 0.5 Total Bases.

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Cleveland vs Pittsburgh Prediction & Odds:
Free MLB Betting Insights for 4/18/25

The Cleveland Guardians and Pittsburgh Pirates open an interleague weekend series at PNC Park on April 18, 2025, with both teams at different stages of their early-season journey but sharing a desire to build momentum. The Guardians, at 8–7, are hovering just above .500 and have played a well-balanced brand of baseball thus far, combining timely hitting with dependable pitching. They’ve shown signs of being a well-rounded team capable of grinding out wins in close games, with Steven Kwan continuing to thrive in the leadoff spot thanks to his .322 average and on-base savvy, while José Ramírez continues to be the offensive catalyst with 4 home runs and 7 RBIs. Cleveland’s success this season has hinged on their ability to manufacture runs without relying too heavily on power, and their contact-driven offense gives them the flexibility to apply pressure across innings. Their pitching staff, while not overpowering, has performed reliably, allowing them to stay competitive in most contests. The bullpen has been a particular strength, with multiple arms capable of closing out tight leads, a valuable asset in early-season games where scoring is often tight. On the other side, the Pirates enter at 5–9 and are still searching for consistency in nearly every phase of the game. Though their record reflects a team that has struggled, there are bright spots—most notably outfielder Matthew Gorski, who has emerged as a key offensive weapon, slashing .360 with 4 home runs and 13 RBIs to lead the team in all three categories. Pittsburgh’s issue hasn’t necessarily been a lack of talent but more so a lack of cohesion and execution, particularly with runners in scoring position and situational pitching.

Their bullpen has not consistently held leads, and their starting pitching has too often failed to get deep into games, putting pressure on the offense to keep up in slugfests or come back from early deficits. This matchup offers the Pirates an opportunity to reset at home, where they hope to find a groove and snap their early-season funk. Defensively, the Pirates have been inconsistent but show potential, especially when playing clean and minimizing errors. Manager Derek Shelton will likely look to get aggressive on the basepaths to create scoring chances, especially if they fall behind early. For Cleveland, the focus will be on continuing to play clean, efficient baseball and putting the ball in play to force Pittsburgh’s defense into action. Historically, the Guardians have held a 6–4 advantage in the last 10 head-to-head meetings, with the over hitting in six of those games—a trend that could continue if both offenses find rhythm early. The key battleground will likely be the middle innings: if Cleveland can get to Pittsburgh’s bullpen with a lead, their own relief corps has proven more than capable of slamming the door. Conversely, if Pittsburgh can grab an early advantage behind Gorski and force Cleveland to chase from behind, they could flip the script and inject life into their early-season campaign. In a matchup where both teams are still figuring themselves out, execution, energy, and situational hitting will determine which side walks away with a much-needed win.

Cleveland Guardians MLB Preview

The Cleveland Guardians enter their Friday matchup at PNC Park with an 8–7 record and a clear intent to continue building on a steady and disciplined start to the 2025 season. Under first-year manager Stephen Vogt, the Guardians have leaned into their strengths—pitching, contact hitting, and defensive execution—to stay competitive in every series despite lacking the firepower of some of their AL Central rivals. At the top of their offensive attack is Steven Kwan, who continues to be one of the league’s most effective table-setters, batting .322 with his trademark plate discipline, line-drive contact, and disruptive speed on the basepaths. Kwan sets the tone for a lineup that thrives on stringing hits together rather than relying solely on home runs, though José Ramírez remains the team’s central source of power. With four home runs and seven RBIs to start the season, Ramírez has been effective in capitalizing on opportunities created by hitters ahead of him, and his presence in the lineup remains a psychological anchor for opposing pitchers. The Guardians have also seen productive at-bats from the supporting cast—Will Brennan and Josh Naylor have delivered timely hits, and Andrés Giménez has continued to provide strong two-way play at second base. As a unit, this offense is patient, tough to strike out, and adept at creating chaos on the bases, a formula that has consistently translated to success even in low-scoring environments. Cleveland’s pitching staff, while not laden with flashy strikeout numbers, has proven more than capable of keeping opponents off balance and limiting big innings.

The rotation has delivered a solid workload with competitive outings, allowing Vogt to manage his bullpen effectively. The relief corps, led by Emmanuel Clase in the closer role, has been particularly sharp, converting save opportunities and protecting leads with late-inning composure. As they face a Pirates team that has stumbled out of the gate at 5–9 but features dangerous hitters like Matthew Gorski, the Guardians will rely on their defensive fundamentals and staff command to control the tempo of the game. Cleveland’s ability to execute small-ball tactics—sacrifice bunts, hit-and-runs, and situational grounders—gives them a tactical edge in tight contests, especially when their pitching holds up. Though their recent record against Pittsburgh is modestly favorable at 6–4 in their last ten head-to-head meetings, the Guardians won’t underestimate a Pirates team hungry to shift the narrative on their young season. Instead, they’ll look to strike early, capitalize on any defensive lapses, and let their reliable pitching staff carry them through the middle and late innings. Friday’s game is an opportunity for Cleveland to inch closer to the division lead while reinforcing their identity as a fundamentally sound, unselfish club that plays with purpose. If Kwan and Ramírez can ignite the offense and the bullpen continues its strong early-season form, the Guardians are well-positioned to start the series with a road victory and continue asserting themselves as a consistent force in the American League.

The Cleveland Guardians (8–7) visit the Pittsburgh Pirates (5–9) at PNC Park on April 18, 2025, in an interleague matchup between two teams aiming to build momentum early in the season. First pitch is scheduled for 6:35 p.m. ET. Cleveland vs Pittsburgh AI Prediction: Free MLB Betting Insights for Apr 18. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Pittsburgh Pirates MLB Preview

The Pittsburgh Pirates return home to PNC Park for Friday night’s interleague clash with the Cleveland Guardians carrying a 5–9 record and an urgent need to reverse course after a rocky start to their 2025 campaign. Despite the sub-.500 mark, there have been bright spots—most notably the electric play of outfielder Matthew Gorski, who has been one of the league’s hottest hitters to open the season. Gorski enters this game slashing .360 with 4 home runs and 13 RBIs, emerging as a much-needed source of power and consistency in a lineup that has otherwise struggled with timely hitting. His ability to deliver in high-leverage situations has kept Pittsburgh competitive in several tight games, and he’ll again be the focal point of an offense that’s seeking rhythm and production outside of its rising star. The Pirates have seen flashes from Jack Suwinski and Ke’Bryan Hayes, but a lack of depth and inconsistent approaches at the plate have resulted in a lineup that’s leaned heavily on solo efforts rather than cohesive rallies. Facing a Cleveland team that specializes in contact, execution, and bullpen efficiency, Pittsburgh knows the margin for error is slim—particularly when offensive opportunities are limited. On the mound, the Pirates are still working to find reliable answers, with their rotation unable to consistently deliver deep outings, putting pressure on a bullpen that has already been asked to do too much in the season’s first few weeks.

Manager Derek Shelton will be looking for a statement start from his Friday night arm, hoping to set the tone early and avoid a scenario where the Guardians can control the pace and leverage their fundamentally sharp small-ball strategy. Pittsburgh’s bullpen has been a mixed bag, with some dependable middle relief but vulnerability in late-inning situations, especially when entering from behind. Defensively, the Pirates have the athleticism and talent to support their pitchers, but lapses in execution—missed cutoff throws, double-play miscues, and occasional mental errors—have cost them in close games. Friday’s contest represents an opportunity to clean that up and begin building momentum at home, where they’ve yet to fully take advantage of their ballpark’s unique dimensions and crowd energy. In recent history, Pittsburgh has dropped six of their last ten matchups to the Guardians, but the Pirates have the tools to turn the tide if they can play crisp defense, get key outs from their starter, and ride Gorski’s hot bat with runners on base. Shelton’s messaging has remained consistent: simplify the game, stay aggressive, and execute fundamentals—particularly against well-drilled teams like Cleveland who rarely beat themselves. If Pittsburgh can follow that blueprint and jump out to an early lead, they may not only grab a valuable win but also begin building the confidence they’ll need to climb out of their early-season slump and stay relevant in a tough National League Central race. This is a pivotal stretch for the Pirates, and it begins with proving they can compete pitch-for-pitch against disciplined opponents like the Guardians on their own turf.

Cleveland vs. Pittsburgh Prop Picks (AI)

AI algorithm Remi is pouring through mountains of data on each player. In fact, anytime the Guardians and Pirates play there’s always several intriguing observations to key in on. Not to mention games played at PNC Park in Apr seemingly never follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: J. Bart over 0.5 Total Bases.

Cleveland vs. Pittsburgh Prediction (AI)

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Remi, our AI sports genius, has been pouring over exorbitant amounts of data from every angle between the Guardians and Pirates and using recursive machine learning and impressive AI to crunch the data to a single cover probability.

The Algorithm has been most focused on the linear correlation of factor emotional bettors tend to put on Cleveland’s strength factors between a Guardians team going up against a possibly unhealthy Pirates team. It appears the true game analytics might reflect a moderate lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI Cleveland vs Pittsburgh picks, computer picks Guardians vs Pirates, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Guardians Betting Trends

The Guardians have a 3–2 record against the spread (ATS) in their last five games.

Pirates Betting Trends

The Pirates are 2–3 ATS in their last five home games.

Guardians vs. Pirates Matchup Trends

In their last 10 head-to-head matchups, the Guardians have a 6–4 record against the Pirates, with the over hitting in 6 of those games.

Cleveland vs. Pittsburgh Game Info

Cleveland vs Pittsburgh starts on April 18, 2025 at 6:40 PM EST.

Spread: Pittsburgh +1.5
Moneyline: Cleveland -134, Pittsburgh +113
Over/Under: 9

Cleveland: (9-9)  |  Pittsburgh: (8-12)

Remi's searched hard and found the best prop for this matchup: J. Bart over 0.5 Total Bases.. Prices move—always shop for the best number.

In their last 10 head-to-head matchups, the Guardians have a 6–4 record against the Pirates, with the over hitting in 6 of those games.

CLE trend: The Guardians have a 3–2 record against the spread (ATS) in their last five games.

PIT trend: The Pirates are 2–3 ATS in their last five home games.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Cleveland vs. Pittsburgh Odds

AI algorithm Remi is pouring through tons of data on each player. In fact, anytime the Cleveland vs Pittsburgh trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme hostile environments seemingly never follow normal, predictable patterns.

Cleveland vs Pittsburgh Opening Odds

CLE Moneyline: -134
PIT Moneyline: +113
CLE Spread: -1.5
PIT Spread: +1.5
Over/Under: 9

Cleveland vs Pittsburgh Live Odds

Games PTS ML SPR O/U
Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
Orioles
Yankees
+196
-240
+1.5 (-105)
-1.5 (-115)
O 9 (-105)
U 9 (-115)
Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
 
-178
 
-1.5 (+115)
O 9.5 (+100)
U 9.5 (-120)
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
+135
-160
+1.5 (-155)
-1.5 (+130)
O 8.5 (-105)
U 8.5 (-115)
Sep 27, 2025 4:05PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:05PM
White Sox
Nationals
+100
-120
+1.5 (-205)
-1.5 (+170)
O 8.5 (-115)
U 8.5 (-105)
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
+196
-240
+1.5 (-110)
-1.5 (-110)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
-130
+110
-1.5 (+130)
+1.5 (-155)
O 8 (-115)
U 8 (-105)
Sep 27, 2025 4:11PM EDT
Detroit Tigers
Boston Red Sox
9/27/25 4:11PM
Tigers
Red Sox
+110
-130
+1.5 (-190)
-1.5 (+158)
O 9 (+100)
U 9 (-120)
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
+175
-210
+1.5 (-120)
-1.5 (+100)
O 8.5 (-115)
U 8.5 (-105)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+115
-135
+1.5 (-190)
-1.5 (+158)
O 7.5 (-120)
U 7.5 (+100)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+150
-178
+1.5 (-145)
-1.5 (+122)
O 8 (-110)
U 8 (-110)
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
+122
-145
+1.5 (-190)
-1.5 (+158)
O 7 (-120)
U 7 (+100)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+118
-140
+1.5 (-190)
-1.5 (+158)
O 7.5 (-115)
U 7.5 (-105)
Sep 27, 2025 9:39PM EDT
Houston Astros
Los Angeles Angels
9/27/25 9:39PM
Astros
Angels
-140
+118
-1.5 (+115)
+1.5 (-135)
O 9 (-110)
U 9 (-110)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+100
-120
+1.5 (-220)
-1.5 (+180)
O 7 (-120)
U 7 (+100)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
+100
-120
+1.5 (-195)
-1.5 (+162)
O 10 (-115)
U 10 (-105)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Cleveland Guardians vs. Pittsburgh Pirates on April 18, 2025 at PNC Park.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
ARI@SD SD -131 57.3% 4 WIN
DET@BOS BOS -115 56.4% 5 WIN
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS