Athletics vs. White Sox
Prediction, Odds & Props
Apr 16 | MLB AI Picks

Updated: 2025-04-14T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Oakland Athletics (7–10) aim to secure a series win against the Chicago White Sox (4–12) tonight at Guaranteed Rate Field, following a decisive 12–3 victory in the series opener. First pitch is scheduled for 7:40 p.m. ET, with Osvaldo Bido (1–1, 3.00 ERA) starting for the Athletics and Jonathan Cannon (0–2, 5.79 ERA) taking the mound for the White Sox.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Apr 16, 2025

Start Time: 7:40 PM EST​

Venue: Rate Field​

White Sox Record: (4-12)

Athletics Record: (7-10)

OPENING ODDS

ATH Moneyline: -154

CHW Moneyline: +129

ATH Spread: -1.5

CHW Spread: +1.5

Over/Under: 7.5

ATH
Betting Trends

  • The Athletics have covered the spread in 7 of their last 10 games, showcasing strong performance against the spread recently.

CHW
Betting Trends

  • The White Sox have struggled against the spread, covering in only 2 of their last 10 games, indicating challenges in meeting betting expectations.

MATCHUP TRENDS

  • The total has gone over in 6 of the Athletics’ last 10 games, suggesting a trend toward higher-scoring contests involving Oakland.

ATH vs. CHW
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: J. Wilson over 0.5 Total Bases.

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Athletics vs Chicago White Sox Prediction & Odds:
Free MLB Betting Insights for 4/16/25

The Oakland Athletics and Chicago White Sox continue their series tonight at Guaranteed Rate Field, where the A’s look to ride their offensive wave and secure another win against a struggling White Sox squad. Oakland enters the contest at 7–10 following an emphatic 12–3 victory in the opener, a performance that showcased their emerging offensive identity and the powerful presence of Tyler Soderstrom, whose MLB-leading 8 home runs and 17 RBIs have helped spark a team that was once thought destined for another rebuilding year. The A’s have averaged 5.4 runs over their last 10 games and have developed a surprising level of consistency at the plate, thanks in large part to the production of Soderstrom and rookie standout Jacob Wilson, who is hitting .333 with excellent situational awareness. Complementing them is Lawrence Butler, who has quietly been one of the more productive bats on the roster with a .295 average, four doubles, and a home run in his last 10 games. This newly energized lineup now faces a White Sox pitching staff that has struggled to find answers and will again test their depth with a chance to build momentum. On the mound for Oakland is Osvaldo Bido, who’s been quietly effective, going 1–1 with a 3.00 ERA and 14 strikeouts in 15 innings while limiting hard contact and working deep enough into games to keep the bullpen fresh. Meanwhile, the White Sox are entering tonight’s matchup with a 4–12 record and the weight of a brutal start pressing down hard. Losers in eight of their last ten, Chicago’s issues have been glaring—an anemic offense paired with ineffective starting pitching.

Over their last 10 games, they’ve managed just 3.0 runs per game and hold a team batting average of .191 during that span. Luis Robert Jr., one of the team’s few star-caliber players, is batting just .154 and has yet to get into rhythm, while Lenyn Sosa leads the club with a modest .240 average. The lack of offensive production has left the pitching staff with little margin for error, and tonight’s starter, Jonathan Cannon, hasn’t been able to deliver much stability. He enters the game 0–2 with a 5.79 ERA and a WHIP north of 1.60, having struggled to find his command and showing vulnerability in the early innings. The White Sox bullpen has been overworked and inconsistent, and the defense—while not disastrous—hasn’t been able to pick up the slack when the pressure mounts. Chicago is a team stuck in a cycle of early deficits, ineffective rallies, and bullpen exposure, and unless their offense finds life quickly, they may be destined for yet another lopsided loss. Statistically and in terms of momentum, this is a matchup that favors Oakland. The Athletics have covered the spread in 7 of their last 10 games and have seen the total go over in 6 of those, thanks in part to their newfound ability to pile up runs in bunches. Conversely, the White Sox have covered in just 2 of their last 10 and show few signs of turning things around without a major offensive breakout. The total has been trending toward the over in Oakland games, which could happen again if the A’s get to Cannon early. The most likely path for the White Sox to be competitive hinges on their starter surviving the first three innings and the offense finally stringing together hits against Bido, who has largely avoided damage this year. If Oakland’s top half continues to produce, and if Bido maintains his rhythm, the Athletics are in an excellent position to pick up their eighth win and push the White Sox even further into early-season turmoil.

Athletics Athletics MLB Preview

The Oakland Athletics head into tonight’s matchup against the Chicago White Sox with quiet confidence and a growing sense that this team may be far more competitive than expected, particularly as their offense continues to surge. Following a dominant 12–3 victory in the series opener, the A’s improved to 7–10 on the season, and perhaps more importantly, demonstrated the kind of offensive firepower that hasn’t been associated with this franchise in recent years. Leading the charge is catcher Tyler Soderstrom, who enters the game atop the MLB leaderboard with 8 home runs and 17 RBIs—an impressive display of power and timing that has helped stabilize the middle of Oakland’s lineup. Alongside him is rookie shortstop Jacob Wilson, who has made an immediate impact at the plate, batting .333 with a mature approach well beyond his years. Lawrence Butler has quietly been a steady force as well, batting .295 with four doubles and providing left-handed balance to a lineup that has begun to produce consistent pressure on opposing pitching staffs. Over the last 10 games, the A’s are averaging 5.4 runs per contest, showing they are capable of producing not only in bursts but also through sustained rallies fueled by discipline and gap-to-gap hitting. On the mound tonight for Oakland is Osvaldo Bido, a right-hander who has emerged as one of the more reliable arms in the rotation. Through 15 innings, Bido carries a 1–1 record with a 3.00 ERA and 14 strikeouts, mixing a live fastball with improved secondary pitches that have helped him limit damage and work through lineups efficiently.

Bido’s ability to pitch deep into games has also allowed Oakland’s bullpen to stay fresh—an essential factor given the A’s don’t carry the deepest relief corps. Still, recent appearances have shown improvement from their middle relievers, and with a rising offensive cushion, Bido can afford to challenge hitters more aggressively in favorable counts. Defensively, Oakland has been crisp, turning routine plays consistently and avoiding costly mistakes that have hampered them in seasons past. Their improved fundamentals and energetic roster, filled with young talent, have begun to shift the tone in a clubhouse once thought to be bound for another year in the AL West basement. From a betting standpoint, the Athletics are trending positively. They’ve covered the spread in seven of their last 10 games, and with their offense rolling and Bido pitching effectively, they’ve become a value team to watch, especially as underdogs. The total has gone over in six of those 10 games, reflecting Oakland’s newfound ability to contribute to high-scoring affairs—a complete reversal from their historically anemic scoring totals. If Soderstrom stays hot and Wilson continues to provide timely hits, Oakland could once again jump on an inexperienced and struggling Chicago starter in Jonathan Cannon. A fast start from the offense combined with another composed outing from Bido would give the Athletics an excellent shot at securing the series and further cementing their reputation as one of the early surprises of the 2025 season.

The Oakland Athletics (7–10) aim to secure a series win against the Chicago White Sox (4–12) tonight at Guaranteed Rate Field, following a decisive 12–3 victory in the series opener. First pitch is scheduled for 7:40 p.m. ET, with Osvaldo Bido (1–1, 3.00 ERA) starting for the Athletics and Jonathan Cannon (0–2, 5.79 ERA) taking the mound for the White Sox. Athletics vs Chicago White Sox AI Prediction: Free MLB Betting Insights for Apr 16. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Chicago White Sox White Sox MLB Preview

The Chicago White Sox enter tonight’s game at Guaranteed Rate Field with a 4–12 record and an increasingly urgent need to reverse what has been a grim start to their 2025 campaign. After being thumped 12–3 in the series opener by the Oakland Athletics, the White Sox are now riding a wave of early-season turbulence, marked by lackluster offense, ineffective starting pitching, and a general lack of momentum across the board. Offensively, the team has been ice cold, averaging just 3.0 runs per game over their last 10 contests and struggling to get anything going in the clutch. Luis Robert Jr., their most potent offensive weapon, has yet to find his stride this season, entering tonight’s game with a batting average of .154 and only one home run. Lenyn Sosa has been one of the few modest bright spots, batting .240 and showing some flashes of control at the plate, but the lineup as a whole has lacked discipline, with too many quick innings and not enough quality plate appearances. With the offense sputtering and offering minimal run support, the pressure has mounted on a pitching staff ill-equipped to carry the team. On the mound tonight will be right-hander Jonathan Cannon, who is still searching for his footing at the Major League level. Cannon enters with an 0–2 record and a 5.79 ERA, along with a 1.64 WHIP that reflects his ongoing struggles with command and limiting baserunners. He’s been tagged early in both of his previous starts, unable to escape damage the second time through opposing lineups, and that has forced the bullpen into longer-than-ideal stints. The relief corps has been overworked and inconsistent, with middle relievers failing to hold close games and late-inning arms often appearing with the team already trailing by multiple runs.

Overall, the team ERA has hovered around 4.92 over the past 10 games, and the lack of pitching depth—both in the rotation and the bullpen—has made it difficult for the White Sox to stay competitive even when the offense does manage to spark. Cannon will need to find his best form quickly tonight against a surging Oakland lineup that has recently torched opposing starters and hit multiple home runs in six of its last 10 games. From a betting standpoint, the White Sox have been one of the least trustworthy teams in baseball to this point. They’ve covered the spread in just two of their last 10 games and continue to underperform relative to expectations at home. The only encouraging angle might be the underdog factor—teams in a deep slump often find an unexpected spark, especially with young pitchers on the mound trying to prove they belong. Still, the White Sox are going to need more than just a one-night turnaround. They must play sharper defense, string together competitive at-bats, and get at least five efficient innings from Cannon to have a real shot at halting Oakland’s momentum. If the top of the lineup—Robert, Sosa, and Yoán Moncada—can finally put something together and avoid the early deficits that have become all too familiar, the White Sox might be able to fight their way back into this series. But if the trends hold, this game could signal yet another step backward in a season that already feels dangerously close to slipping away.

Athletics vs. Chicago White Sox Prop Picks (AI)

Remi is pouring through tons of datapoints on each player. In fact, anytime the Athletics and White Sox play there’s always several intriguing observations to key in on. Not to mention games played at Rate Field in Apr seemingly never follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: J. Wilson over 0.5 Total Bases.

Athletics vs. Chicago White Sox Prediction (AI)

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Remi, our AI sports genius, has been pouring over mountains of data from every past game between the Athletics and White Sox and using recursive machine learning and cutting-edge AI to crunch the data to a single cover probability.

Interestingly enough, the data has been most focused on the linear correlation of factor knucklehead sportsbettors tend to put on coaching factors between a Athletics team going up against a possibly improved White Sox team. It appears the true game analytics appear to reflect a strong lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI Athletics vs Chicago White Sox picks, computer picks Athletics vs White Sox, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
MLB 9/26 DET@BOS UNLOCK THIS PICK 5 EXECUTIVE Locked EXECUTIVE
MLB 9/26 BAL@NYY UNLOCK THIS PICK 4 INTEL Locked INTEL
MLB 9/26 ARI@SD UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
MLB 9/26 NYM@MIA UNLOCK THIS PICK 1 INTEL Locked INTEL
MLB 9/26 NYM@MIA GET FREE PICK NOW 1
MLB 9/26 COL@SF UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Athletics Betting Trends

The Athletics have covered the spread in 7 of their last 10 games, showcasing strong performance against the spread recently.

White Sox Betting Trends

The White Sox have struggled against the spread, covering in only 2 of their last 10 games, indicating challenges in meeting betting expectations.

Athletics vs. White Sox Matchup Trends

The total has gone over in 6 of the Athletics’ last 10 games, suggesting a trend toward higher-scoring contests involving Oakland.

Athletics vs. Chicago White Sox Game Info

Athletics vs Chicago White Sox starts on April 16, 2025 at 7:40 PM EST.

Spread: Chicago White Sox +1.5
Moneyline: Athletics -154, Chicago White Sox +129
Over/Under: 7.5

Athletics: (7-10)  |  Chicago White Sox: (4-12)

Remi's searched hard and found the best prop for this matchup: J. Wilson over 0.5 Total Bases.. Prices move—always shop for the best number.

The total has gone over in 6 of the Athletics’ last 10 games, suggesting a trend toward higher-scoring contests involving Oakland.

ATH trend: The Athletics have covered the spread in 7 of their last 10 games, showcasing strong performance against the spread recently.

CHW trend: The White Sox have struggled against the spread, covering in only 2 of their last 10 games, indicating challenges in meeting betting expectations.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Athletics vs. Chicago White Sox Odds

Remi is pouring through tons of data points on each player. In fact, anytime the Athletics vs Chicago White Sox trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme altitude rarely follow normal, predictable patterns.

Athletics vs Chicago White Sox Opening Odds

ATH Moneyline: -154
CHW Moneyline: +129
ATH Spread: -1.5
CHW Spread: +1.5
Over/Under: 7.5

Athletics vs Chicago White Sox Live Odds

Games PTS ML SPR O/U
Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
Orioles
Yankees
+190
-235
+1.5 (-110)
-1.5 (-110)
O 8.5 (-120)
U 8.5 (+100)
Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
 
-180
 
-1.5 (+115)
O 9.5 (-105)
U 9.5 (-115)
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
+130
-155
+1.5 (-155)
-1.5 (+130)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:06PM
White Sox
Nationals
+100
-120
-1.5 (+165)
+1.5 (-200)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
+185
-225
+1.5 (-110)
-1.5 (-110)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
-130
+110
-1.5 (+125)
+1.5 (-150)
O 8 (-115)
U 8 (-105)
Sep 27, 2025 4:11PM EDT
Detroit Tigers
Boston Red Sox
9/27/25 4:11PM
Tigers
Red Sox
+125
-150
+1.5 (-180)
-1.5 (+150)
O 9 (+100)
U 9 (-120)
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
+170
-205
+1.5 (-120)
-1.5 (+100)
O 8.5 (-115)
U 8.5 (-105)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+125
-150
+1.5 (-180)
-1.5 (+150)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+145
-175
+1.5 (-155)
-1.5 (+130)
O 8 (-110)
U 8 (-110)
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
+135
-165
+1.5 (-180)
-1.5 (+150)
O 7 (-120)
U 7 (+100)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+115
-140
+1.5 (-195)
-1.5 (+160)
O 7.5 (-120)
U 7.5 (+100)
Sep 27, 2025 9:39PM EDT
Houston Astros
Los Angeles Angels
9/27/25 9:39PM
Astros
Angels
-165
+135
-1.5 (+105)
+1.5 (-125)
O 9 (+100)
U 9 (-120)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+105
-125
+1.5 (-205)
-1.5 (+170)
O 7.5 (+105)
U 7.5 (-125)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
+100
-120
-1.5 (+150)
+1.5 (-180)
O 10 (-110)
U 10 (-110)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Athletics Athletics vs. Chicago White Sox White Sox on April 16, 2025 at Rate Field.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS
CIN@ARI KEBRYAN HAYES STRIKEOUTS UNDER 0.5 56.2% 6 WIN
LAD@SD SD +110 50.9% 6 WIN