Padres vs Athletics Prediction — AI Finds CAN'T MISS MLB Lines & Props (Apr 08)
Updated: 2025-04-06T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The San Diego Padres will face the Oakland Athletics on April 8, 2025, at Sutter Health Park in West Sacramento, California, for the second game of their three-game series. Both teams have had contrasting starts to the season, with the Padres holding a 9-2 record, placing them atop the National League West, while the Athletics are at 4-7, struggling to find consistency.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Apr 08, 2025
Start Time: 10:05 PM EST
Venue: Sutter Health Park
Athletics Record: (4-7)
Padres Record: (9-2)
OPENING ODDS
SD Moneyline: -146
ATH Moneyline: +123
SD Spread: -1.5
ATH Spread: +1.5
Over/Under: 8.5
SD
Betting Trends
- The Padres have been favored in six games this season, winning all six outright. They have also covered the spread in five of those games, showcasing their dominance when playing as the favorite. Their moneyline performance stands at 9-2, reflecting their strong form early in the season.
ATH
Betting Trends
- The Athletics have faced challenges, holding a 4-7 record overall and an 0-4 mark at home. As underdogs, they have covered the spread in three of their last five games, indicating some resilience despite their struggles. Their moneyline performance reflects their challenges, but they have shown moments of competitiveness.
MATCHUP TRENDS
- The over/under for this game is set at 8.5 runs, suggesting expectations of a moderately high-scoring contest. Historical trends between these teams show that the over has hit in four of their last five matchups, indicating a propensity for high-scoring games. Additionally, the Athletics have been competitive against the spread in recent games, covering in four of their last six matchups, despite their overall struggles.
SD vs. ATH
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: L. Butler over 5.5 Fantasy Score.
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San Diego vs Athletics Prediction & Odds:
Free MLB Betting Insights for 4/8/25
Despite this power, Oakland’s offense has been inconsistent, often failing to generate the kind of run support needed to back up a pitching staff that has struggled with depth. Pitching will be a key issue for the Athletics as they look to compete against a Padres team that has been strong in all phases of the game. Veteran Jeffrey Springs, with a 4.00 ERA and 1-1 record, will be tasked with taking the mound for Oakland. Springs’ ability to limit the Padres’ explosive hitters will be crucial in keeping the game close. The Athletics will need their pitching staff to step up and avoid any big innings, as San Diego’s offense is capable of capitalizing on any mistakes. Defensively, the Athletics have been solid but will need to execute perfectly against a team that can generate offense in various ways. They will also need to avoid the home-field struggles that have plagued them so far, as they’ve lost four straight games at Sutter Health Park. If the Athletics can continue their power surge while getting a quality start from Springs, they could challenge the Padres, but they’ll need a much more consistent performance overall to secure a win. Sutter Health Park is known for its hitter-friendly conditions, which will add an interesting layer to this matchup. With the Padres’ deep lineup and the Athletics’ power-hitting capability, fans can expect a potentially high-scoring game. San Diego’s pitching staff, led by Cease, will need to make precise pitches and avoid leaving the ball over the plate in a park that can turn routine fly balls into home runs. The Athletics will need to maximize their power potential and capitalize on any mistakes from the Padres’ pitchers. Defensively, both teams will need to execute, as extra-base hits are always a possibility in such a stadium. The Padres, with their strong pitching and deep lineup, will likely be the favorites, but the Athletics have the potential to keep the game close if their pitchers can step up and their power hitters continue their hot start. This game represents a chance for the Padres to continue their strong start to the season and demonstrate their superiority over a team still looking to find its footing. For the Athletics, it’s a pivotal opportunity to bounce back from their struggles and get a much-needed win at home to boost their confidence and standings in the AL West. A victory here would provide valuable momentum for both teams, with the Padres looking to extend their lead in the standings and the Athletics trying to turn their season around.
Starting the series with a W! pic.twitter.com/vMj4HZHSwd
— San Diego Padres (@Padres) April 8, 2025
San Diego Padres MLB Preview
The San Diego Padres enter their April 8, 2025, matchup against the Oakland Athletics with a strong 9-2 record, showcasing their offensive depth and pitching prowess. Their lineup has been dynamic, with stars like Fernando Tatis Jr. and Jackson Merrill leading the charge at the plate. Tatis, who has a .381 batting average and has shown his power with two home runs, continues to be a key player for the Padres. Merrill, with three home runs and 10 RBIs, has been another bright spot, providing crucial support in the middle of the order. On the mound, Dylan Cease has been effective, posting a 3.37 ERA with 14 strikeouts in his first few starts of the season. The Padres’ pitching staff as a whole has been a major strength, with Cease anchoring the rotation. Their bullpen has also been effective, maintaining leads in close games. The Padres have been impressive in games where they have been favored, winning all six of those contests, and their strong start suggests they are one of the top teams in the National League West. However, they will need to continue building on their momentum and ensure that their offense continues to fire on all cylinders as they face off against a tough Athletics team on the road. Defensively, the Padres have been solid, particularly in the infield, where players like Ha-Seong Kim and Manny Machado provide stability and gold-glove-caliber defense. In the outfield, Tatis’ range and ability to cover ground make him a key asset, and with a solid pitching staff behind them, the Padres have the tools to keep the Athletics’ offense in check.
The key for the Padres in this game will be staying aggressive offensively while ensuring their pitchers execute their game plan effectively. In a hitter-friendly park like Sutter Health Park, where the ball can fly out of the yard, the Padres’ pitchers will need to avoid leaving balls over the plate, particularly against a powerful Athletics lineup. If the Padres can maintain their offensive production, get a solid start from Cease, and avoid mistakes in the field, they should have the advantage in this game. Their ability to capitalize on scoring opportunities, particularly with runners in scoring position, will be critical to securing the win and further solidifying their position in the standings. For the Padres to win this game, they need to continue their strong road play and build on their success as favorites. Their offense has the potential to score in a variety of ways, whether it’s through power hitting, timely contact, or aggressive baserunning. If the Padres’ pitchers can keep the Athletics from getting comfortable at the plate, they’ll be able to control the game. A win for the Padres would help extend their lead in the division, while sending a message that they are one of the top teams in the league. With a solid lineup, a reliable pitching staff, and a strong bullpen, the Padres have the tools to maintain their success throughout the season. This game against the Athletics provides a good opportunity for the Padres to continue their strong form and demonstrate their ability to perform consistently on the road. A victory here would be crucial for the Padres to stay on top of the standings and set the tone for the rest of their season.

Credit: USA TODAY/IMAGN
Athletics Athletics MLB Preview
The Oakland Athletics return home to Sutter Health Park on April 8, 2025, with a 4-7 record, looking to improve after a tough start to the season. Despite their struggles, the Athletics have shown flashes of offensive power, ranking at the top of the league with 18 home runs, averaging 1.6 per game. Tyler Soderstrom has been a standout for the team, leading the offense with six home runs and 10 RBIs, while hitting .381. The Athletics will look to continue their power surge, with Soderstrom, along with other key contributors like Jacob Wilson and Brent Rooker, aiming to generate enough offense to support their pitching staff. However, Oakland’s offense has been inconsistent, often struggling to capitalize on scoring opportunities. They will need to find better consistency across the lineup to compete with a formidable team like the Padres, who have been dominant early in the season. On the mound, Jeffrey Springs will take the ball for the Athletics in this crucial game. Springs has posted a 4.00 ERA and a 1-1 record, but his ability to limit the Padres’ powerful offense will be key in keeping the Athletics competitive. The Padres, led by hitters like Fernando Tatis Jr. and Jackson Merrill, have been scoring at will, and Springs will need to pitch with precision to keep them from putting up big numbers. The Athletics’ bullpen has been one of the weaker areas of their game this season, and Springs will need to provide a quality start to avoid overexposing their relief pitchers, particularly in the later innings. The Athletics have struggled at home, having lost their last four games at Sutter Health Park, so Springs will need to provide a solid outing to help break that losing streak and give the team a chance to get back on track.
Defensively, the Athletics will need to be sharp in a hitter-friendly ballpark like Sutter Health Park. The spacious outfield will require players like Esteury Ruiz and Brent Rooker to cover a lot of ground, especially against a Padres lineup that has the power to turn any pitch into a scoring opportunity. The infield, with solid players like Tony Kemp and Aledmys Díaz, will need to execute well on turning double plays and preventing the Padres from getting easy extra bases. The Athletics have the tools to be competitive, but they will need to avoid defensive lapses that could give the Padres additional opportunities. Additionally, Oakland’s base-running could play a significant role, with players like Ruiz and Soderstrom capable of putting pressure on the Padres’ defense and creating scoring chances. For the Athletics to have a shot at victory, they must play a complete game, combining timely hitting, strong defense, and a solid start from Springs to keep the Padres’ offense in check. This game is crucial for the Athletics to regain some momentum and get back on track after a difficult start to the season. While the Padres are the favorites, given their strong record and all-around performance, the Athletics have the potential to pull off an upset if they can execute effectively. A win in this game would help the Athletics break their home losing streak, boost their confidence, and allow them to build momentum moving forward. The Athletics will need to improve their consistency across both sides of the ball—capitalizing on their power hitters, tightening up their defense, and getting a quality performance from their starting pitchers to give themselves a chance to compete with one of the top teams in the league.
— Athletics (@Athletics) April 8, 2025
San Diego vs. Athletics Prop Picks (AI)
San Diego vs. Athletics Prediction (AI)

Remi, our AI sports wizard, has been pouring over exorbitant amounts of data from every angle between the Padres and Athletics and using recursive machine learning and cutting-edge AI to boil down the data to a single cover probability.
Remi has been most fixated on the linear correlation of factor emotional bettors tend to put on San Diego’s strength factors between a Padres team going up against a possibly strong Athletics team. We’ve found the true game analytics appear to reflect a slight lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.
Below is our current AI San Diego vs Athletics picks, computer picks Padres vs Athletics, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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Padres Betting Trends
The Padres have been favored in six games this season, winning all six outright. They have also covered the spread in five of those games, showcasing their dominance when playing as the favorite. Their moneyline performance stands at 9-2, reflecting their strong form early in the season.
Athletics Betting Trends
The Athletics have faced challenges, holding a 4-7 record overall and an 0-4 mark at home. As underdogs, they have covered the spread in three of their last five games, indicating some resilience despite their struggles. Their moneyline performance reflects their challenges, but they have shown moments of competitiveness.
Padres vs. Athletics Matchup Trends
The over/under for this game is set at 8.5 runs, suggesting expectations of a moderately high-scoring contest. Historical trends between these teams show that the over has hit in four of their last five matchups, indicating a propensity for high-scoring games. Additionally, the Athletics have been competitive against the spread in recent games, covering in four of their last six matchups, despite their overall struggles.
San Diego vs. Athletics Game Info
What time does San Diego vs Athletics start on April 08, 2025?
San Diego vs Athletics starts on April 08, 2025 at 10:05 PM EST.
Where is San Diego vs Athletics being played?
Venue: Sutter Health Park.
What are the opening odds for San Diego vs Athletics?
Spread: Athletics +1.5
Moneyline: San Diego -146, Athletics +123
Over/Under: 8.5
What are the records for San Diego vs Athletics?
San Diego: (9-2) | Athletics: (4-7)
What is the AI best bet for San Diego vs Athletics?
Remi's searched hard and found the best prop for this matchup: L. Butler over 5.5 Fantasy Score.. Prices move—always shop for the best number.
What are San Diego vs Athletics trending bets?
The over/under for this game is set at 8.5 runs, suggesting expectations of a moderately high-scoring contest. Historical trends between these teams show that the over has hit in four of their last five matchups, indicating a propensity for high-scoring games. Additionally, the Athletics have been competitive against the spread in recent games, covering in four of their last six matchups, despite their overall struggles.
What are San Diego trending bets?
SD trend: The Padres have been favored in six games this season, winning all six outright. They have also covered the spread in five of those games, showcasing their dominance when playing as the favorite. Their moneyline performance stands at 9-2, reflecting their strong form early in the season.
What are Athletics trending bets?
ATH trend: The Athletics have faced challenges, holding a 4-7 record overall and an 0-4 mark at home. As underdogs, they have covered the spread in three of their last five games, indicating some resilience despite their struggles. Their moneyline performance reflects their challenges, but they have shown moments of competitiveness.
Where can I find AI Picks for San Diego vs Athletics?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
San Diego vs. Athletics Odds
Remi is pouring through tons of data points on each player. In fact, anytime the San Diego vs Athletics trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme altitude can often follow normal, predictable patterns.
San Diego vs Athletics Opening Odds
SD Moneyline:
-146 ATH Moneyline: +123
SD Spread: -1.5
ATH Spread: +1.5
Over/Under: 8.5
San Diego vs Athletics Live Odds
Games | PTS | ML | SPR | O/U | |
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Oct 19, 2025 8:04PM EDT
Seattle Mariners
Toronto Blue Jays
10/19/25 8:04PM
Mariners
Blue Jays
|
–
–
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+104
-127
|
+1.5 (-206)
-1.5 (+166)
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O 7.5 (-116)
U 7.5 (-104)
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MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers San Diego Padres vs. Athletics Athletics on April 08, 2025 at Sutter Health Park.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
TOR@SEA | OVER 7 | 54.9% | 3 | WIN |
LAD@MIL | UNDER 7.5 | 56.6% | 6 | WIN |
TOR@NYY | OVER 8 | 54.9% | 4 | WIN |
TOR@NYY | CARLOS RODON OVER 1.5 TOTAL WALKS ALLOWED | 53.3% | 3 | WIN |
NYY@TOR | OVER 7.5 | 54.8% | 2 | WIN |
LAD@PHI | OVER 7 | 53.8% | 3 | WIN |
SD@CHC | CHC -109 | 53.8% | 3 | WIN |
SD@CHC | OVER 7.5 | 54.5% | 4 | LOSS |
SD@CHC | CHC -111 | 54.8% | 4 | LOSS |
CIN@LAD | SHOHEI OHTANI OVER 1.5 BASES | 53.5% | 3 | WIN |
BOS@NYY | OVER 7 | 53.8% | 3 | LOSS |
CIN@LAD | ELLY DE LA CRUZ OVER 0.5 BASES | 54.4% | 4 | LOSS |
ARI@SD | SD -131 | 57.3% | 4 | WIN |
DET@BOS | BOS -115 | 56.4% | 5 | WIN |
NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
LAA@COL | COL +108 | 50.5% | 3 | WIN |
TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
KC@PHI | PHI -130 | 58.3% | 4 | WIN |
LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
KC@CLE | KC -104 | 52.0% | 3 | WIN |
CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |