Yankees vs. Pirates
Prediction, Odds & Props
Apr 06 | MLB AI Picks

Updated: 2025-04-04T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

On April 6, 2025, the New York Yankees will face the Pittsburgh Pirates at PNC Park in Pittsburgh. The Yankees aim to continue their strong start to the season, while the Pirates look to improve their performance after a challenging beginning.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Apr 06, 2025

Start Time: 1:35 PM EST​

Venue: PNC Park​

Pirates Record: (2-7)

Yankees Record: (6-2)

OPENING ODDS

NYY Moneyline: -166

PIT Moneyline: +140

NYY Spread: -1.5

PIT Spread: +1.5

Over/Under: 9

NYY
Betting Trends

  • The Yankees have been favored in 130 games this season, winning 74 (56.9%) of those contests, and in their last 10 games, they have covered the spread 6 times and failed to cover 4 times.

PIT
Betting Trends

  • The Pirates have been underdogs in 97 games this season, securing victories in 40 (41.2%) of them, and over their past 10 games, they have covered the spread 4 times and failed to cover 6 times.

MATCHUP TRENDS

  • The Yankees have covered the spread in 6 of their last 10 games against the Pirates, while the Pirates have covered in 4 of those matchups, indicating a relatively balanced performance between the two teams.

NYY vs. PIT
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: W. Warren over 1.5 Earned Runs.

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New York Yankees vs Pittsburgh Prediction & Odds:
Free MLB Betting Insights for 4/6/25

The New York Yankees (6-2) will face the Pittsburgh Pirates (2-7) on April 6, 2025, at PNC Park in Pittsburgh, and the matchup promises to be an exciting clash between two teams with contrasting early-season performances. The Yankees, fresh off a strong start to the season, are looking to continue their momentum as they visit the Pirates for a three-game series. The Yankees have been firing on all cylinders, especially on offense, with Aaron Judge leading the way with multiple home runs in the opening games, and Cody Bellinger providing additional power in the middle of the order. Their offense, as a whole, has been producing consistently, averaging over 5 runs per game, thanks to contributions from hitters like Anthony Volpe and Giancarlo Stanton. The depth of their lineup makes them a dangerous team for any opponent, as they have the ability to put up runs quickly and efficiently. On the mound, the Yankees have a solid rotation that has allowed them to stay competitive. Max Fried, the key acquisition for the Yankees this offseason, will look to rebound after a mixed debut performance, aiming to deliver a strong start to help the Yankees extend their early-season dominance. Marcus Stroman, known for his crafty pitching style, will also be crucial to the team’s success as he looks to provide a quality start and shut down opposing hitters. The bullpen has been strong as well, with reliable arms like Clay Holmes and Jonathan Loáisiga providing late-game relief, ensuring that the Yankees can close out games with confidence.

Meanwhile, the Pittsburgh Pirates come into this game struggling at 2-7, with their offense being a major concern early on. Despite the presence of standout players like Oneil Cruz, who has shown flashes of potential, the Pirates’ offense has been limited, scoring no more than four runs in any of their first seven games. The Pirates have struggled to generate consistent offense and have been unable to capitalize on scoring opportunities. Their pitchers have also faced challenges, with Mitch Keller being the bright spot in the rotation. Keller, who signed a five-year extension in the offseason, will look to build on his solid performance from his previous start, where he pitched six innings of one-run ball. Keller’s ability to manage the Yankees’ powerful offense will be key to keeping the game close. The Pirates’ bullpen, while showing some potential, will need to step up in support of Keller and the rest of the rotation. Defensively, the Pirates have shown flashes of solid play but will need to tighten up to avoid errors that could cost them in a game against a team like the Yankees. Manager Derek Shelton will be focused on addressing the team’s struggles at the plate and finding ways to exploit any weaknesses in the Yankees’ pitching. While the Pirates are facing a tough challenge, their home-field advantage at PNC Park could provide them with a spark. With both teams possessing high-caliber talent, this game will come down to whether the Pirates can overcome their offensive struggles and whether the Yankees can maintain their dominance on both sides of the ball. The Pirates need a strong performance from Keller and a breakout offensive showing to have a chance in this matchup, while the Yankees will aim to continue their dominant form and extend their strong start to the season.

New York Yankees Yankees MLB Preview

The New York Yankees (6-2) come into their April 6, 2025, matchup against the Pittsburgh Pirates at PNC Park looking to continue their strong early-season performance. The Yankees have been dominant both offensively and on the mound, and they’ll look to keep their momentum going in this road game. Offensively, they’ve been firing on all cylinders, with Aaron Judge leading the charge. Judge has been an offensive juggernaut to start the season, hitting multiple home runs and driving in key runs. Alongside him, Cody Bellinger has provided a steady bat in the middle of the lineup, offering a mix of power and contact hitting. The Yankees’ lineup is well-rounded, with contributors like Anthony Volpe, Giancarlo Stanton, and Gleyber Torres adding depth to the batting order. With a lineup this deep, the Yankees are capable of scoring quickly and in a variety of ways, putting pressure on opposing pitchers every time they step to the plate. Their offensive approach revolves around power, plate discipline, and capitalizing on mistakes, making them one of the most dangerous teams to face in the league. On the mound, the Yankees have a rotation that is poised to keep them competitive throughout the season. Max Fried, who was a key offseason acquisition for the Yankees, will be tasked with starting this game. Fried, who has been a consistent performer throughout his career, aims to bounce back from a mixed debut performance with the Yankees and prove why he’s a top-tier starter. His ability to control the strike zone, avoid walks, and keep hitters off balance will be crucial against the Pirates’ offense. Marcus Stroman, another seasoned veteran in the Yankees’ rotation, will also look to build on his solid start and deliver another quality outing.

Stroman’s crafty pitching and ability to induce weak contact will be important as he faces a Pirates team that has struggled offensively in the early part of the season. The Yankees’ bullpen, which has been effective so far in 2025, will play a key role in closing out games. With arms like Clay Holmes and Jonathan Loáisiga, the bullpen provides reliable late-game support and gives manager Aaron Boone the confidence to go to his relievers when needed. While the Yankees’ pitching staff has been a strength, their success has been aided by their potent offense, which has consistently provided run support. The Yankees will aim to continue their offensive dominance and solid pitching as they take on the Pirates. On the defensive side, the Yankees have been sharp, minimizing errors and playing disciplined baseball. This will be important in a game against a Pirates team that has shown flashes of talent but has struggled to generate consistent offense. The Yankees’ focus will be on keeping the pressure on the Pirates by maintaining offensive consistency and getting strong innings from Fried and Stroman. With their well-rounded team, the Yankees are positioned to take another win on the road as they continue their pursuit of a championship in 2025. The Pirates will present a challenge, but with their current form, the Yankees are likely to extend their early-season success and move one step closer to a strong postseason push.

On April 6, 2025, the New York Yankees will face the Pittsburgh Pirates at PNC Park in Pittsburgh. The Yankees aim to continue their strong start to the season, while the Pirates look to improve their performance after a challenging beginning. New York Yankees vs Pittsburgh AI Prediction: Free MLB Betting Insights for Apr 06. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Pittsburgh Pirates MLB Preview

The Pittsburgh Pirates (2-7) will look to get back on track when they face the New York Yankees on April 6, 2025, at PNC Park. After a tough start to the season, the Pirates are in need of a breakout performance to spark their campaign. Their offense has been the primary issue, with the team struggling to generate consistent run support. Averaging fewer than 4 runs per game, the Pirates’ batting order has been underperforming, and they have failed to produce at critical moments. Oneil Cruz, however, has been one of the few bright spots on offense, showcasing his potential with solid hitting and power. Cruz’s ability to generate exit velocities and get on base is key to the Pirates’ offense, but he can’t carry the load alone. The Pirates will need contributions from players like Bryan Reynolds, who has the potential to be a difference-maker, and Ke’Bryan Hayes, who can provide spark and timely hits. If the Pirates are to compete with the Yankees, their offense will need to step up and produce consistently. Starting pitcher Mitch Keller, who was recently given a five-year contract extension, will look to build on his solid performance from his last start, where he pitched six innings of one-run ball. Keller has the stuff to dominate on the mound, and his ability to control the game and limit damage will be key in keeping the Pirates in the game.

The pressure will be on Keller to keep the Yankees’ lineup at bay, especially with power hitters like Aaron Judge and Cody Bellinger threatening from the plate. While Keller’s performance will be crucial, the Pirates’ bullpen will also need to step up in support. The bullpen has been inconsistent thus far but has the potential to help shut down opposing offenses if they can limit walks and keep hitters off balance. Manager Derek Shelton will look for improvements in all aspects of the game, particularly the offense, to give the team a chance to secure a win against a formidable Yankees team. Defensively, the Pirates have been solid but have occasionally faltered with errors, and minimizing mistakes will be crucial, especially when facing an offense as potent as the Yankees. With the Yankees coming in strong, the Pirates need to use their home-field advantage at PNC Park to their benefit. They’ll need to capitalize on every scoring opportunity, play sharp defense, and get a strong outing from Keller to have a chance. The Yankees, with their explosive offense and deep pitching staff, will be tough opponents, but if the Pirates can limit mistakes and put together a complete performance, they will be in with a chance to spring the upset. This game is pivotal for the Pirates to start turning their season around, and a win against a team like the Yankees would provide much-needed confidence as they try to fight back from their early struggles.

New York Yankees vs. Pittsburgh Prop Picks (AI)

AI algorithm Remi is pouring through tons of stats on each player. In fact, anytime the Yankees and Pirates play there’s always several intriguing trends to key in on. Not to mention games played at PNC Park in Apr seemingly never follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: W. Warren over 1.5 Earned Runs.

New York Yankees vs. Pittsburgh Prediction (AI)

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Remi, our AI sports algorithm, has been pouring over mountains of data from every angle between the Yankees and Pirates and using recursive machine learning and impressive AI to crunch the data to a single cover probability.

The Algorithm has been most fixated on the trending weight knucklehead sportsbettors often put on New York Yankees’s strength factors between a Yankees team going up against a possibly improved Pirates team. It appears the true game analytics might reflect a moderate lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI New York Yankees vs Pittsburgh picks, computer picks Yankees vs Pirates, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
MLB 9/26 DET@BOS UNLOCK THIS PICK 5 EXECUTIVE Locked EXECUTIVE
MLB 9/26 BAL@NYY UNLOCK THIS PICK 4 INTEL Locked INTEL
MLB 9/26 ARI@SD UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
MLB 9/26 NYM@MIA UNLOCK THIS PICK 1 INTEL Locked INTEL
MLB 9/26 NYM@MIA GET FREE PICK NOW 1
MLB 9/26 COL@SF UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Yankees Betting Trends

The Yankees have been favored in 130 games this season, winning 74 (56.9%) of those contests, and in their last 10 games, they have covered the spread 6 times and failed to cover 4 times.

Pirates Betting Trends

The Pirates have been underdogs in 97 games this season, securing victories in 40 (41.2%) of them, and over their past 10 games, they have covered the spread 4 times and failed to cover 6 times.

Yankees vs. Pirates Matchup Trends

The Yankees have covered the spread in 6 of their last 10 games against the Pirates, while the Pirates have covered in 4 of those matchups, indicating a relatively balanced performance between the two teams.

New York Yankees vs. Pittsburgh Game Info

New York Yankees vs Pittsburgh starts on April 06, 2025 at 1:35 PM EST.

Spread: Pittsburgh +1.5
Moneyline: New York Yankees -166, Pittsburgh +140
Over/Under: 9

New York Yankees: (6-2)  |  Pittsburgh: (2-7)

Remi's searched hard and found the best prop for this matchup: W. Warren over 1.5 Earned Runs.. Prices move—always shop for the best number.

The Yankees have covered the spread in 6 of their last 10 games against the Pirates, while the Pirates have covered in 4 of those matchups, indicating a relatively balanced performance between the two teams.

NYY trend: The Yankees have been favored in 130 games this season, winning 74 (56.9%) of those contests, and in their last 10 games, they have covered the spread 6 times and failed to cover 4 times.

PIT trend: The Pirates have been underdogs in 97 games this season, securing victories in 40 (41.2%) of them, and over their past 10 games, they have covered the spread 4 times and failed to cover 6 times.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

New York Yankees vs. Pittsburgh Odds

AI algorithm Remi is pouring through mountains of data on each line. In fact, anytime the New York Yankees vs Pittsburgh trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme travel distance seemingly never follow normal, predictable betting trends.

New York Yankees vs Pittsburgh Opening Odds

NYY Moneyline: -166
PIT Moneyline: +140
NYY Spread: -1.5
PIT Spread: +1.5
Over/Under: 9

New York Yankees vs Pittsburgh Live Odds

Games PTS ML SPR O/U
Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
Orioles
Yankees
+190
-235
+1.5 (-110)
-1.5 (-110)
O 8.5 (-120)
U 8.5 (+100)
Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
 
-175
 
-1.5 (+115)
O 9.5 (-105)
U 9.5 (-115)
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
+130
-155
+1.5 (-155)
-1.5 (+130)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:06PM
White Sox
Nationals
+100
-120
-1.5 (+165)
+1.5 (-200)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
+185
-225
+1.5 (-110)
-1.5 (-110)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
-130
+110
-1.5 (+125)
+1.5 (-150)
O 8.5 (-105)
U 8.5 (-115)
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
+170
-205
+1.5 (-120)
-1.5 (+100)
O 8.5 (-115)
U 8.5 (-105)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+125
-150
+1.5 (-180)
-1.5 (+150)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+140
-170
+1.5 (-155)
-1.5 (+130)
O 8 (-110)
U 8 (-110)
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
+135
-165
+1.5 (-180)
-1.5 (+150)
O 7 (-120)
U 7 (+100)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+115
-140
+1.5 (-190)
-1.5 (+155)
O 7.5 (-120)
U 7.5 (+100)
Sep 27, 2025 9:39PM EDT
Houston Astros
Los Angeles Angels
9/27/25 9:39PM
Astros
Angels
-165
+135
-1.5 (+105)
+1.5 (-125)
O 9 (+100)
U 9 (-120)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+100
-120
-1.5 (+170)
+1.5 (-205)
O 7.5 (-110)
U 7.5 (-110)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
+100
-120
-1.5 (+150)
+1.5 (-180)
O 10 (-110)
U 10 (-110)

MLB Past Picks

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We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers New York Yankees Yankees vs. Pittsburgh Pirates on April 06, 2025 at PNC Park.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS
CIN@ARI KEBRYAN HAYES STRIKEOUTS UNDER 0.5 56.2% 6 WIN
LAD@SD SD +110 50.9% 6 WIN