Reds vs. Brewers
Prediction, Odds & Props
Apr 05 | MLB AI Picks

Updated: 2025-04-03T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Cincinnati Reds are set to face the Milwaukee Brewers on April 5, 2025, at American Family Field in Milwaukee, Wisconsin, with the first pitch scheduled for 7:10 PM ET. This matchup marks the third game in a four-game series between these National League Central division rivals.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Apr 05, 2025

Start Time: 7:10 PM EST​

Venue: American Family Field​

Brewers Record: (4-4)

Reds Record: (2-6)

OPENING ODDS

CIN Moneyline: -116

MIL Moneyline: -104

CIN Spread: -1.5

MIL Spread: +1.5

Over/Under: 8

CIN
Betting Trends

  • The Reds have struggled against the spread (ATS) recently, failing to cover in their last four games. Their offense has been notably underperforming, averaging just 1.5 runs per game during this stretch.

MIL
Betting Trends

  • Conversely, the Brewers have been successful ATS, covering in their last four games. They’ve managed to win close contests, with three of these victories decided by two runs or fewer.

MATCHUP TRENDS

  • The Brewers’ recent ATS success is highlighted by their ability to win tight games, showcasing resilience in high-pressure situations. Meanwhile, the Reds’ offensive struggles have contributed to their ATS shortcomings, emphasizing the importance of generating runs to stay competitive.

CIN vs. MIL
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: E. De La Cruz over 0.5 Total Bases.

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Cincinnati vs Milwaukee Prediction & Odds:
Free MLB Betting Insights for 4/5/25

Saturday night’s game between the Cincinnati Reds and the Milwaukee Brewers at American Family Field sets the stage for a pivotal early-season matchup between two National League Central rivals navigating different trajectories. The Brewers enter with a 3–4 record, riding the momentum of a few strong offensive showings and a recent 5–0 victory, while the Reds arrive at 2–5 and desperate to break free from a string of low-scoring performances. Each team has been plagued with inconsistency—Milwaukee struggling to string together quality starts from the mound and Cincinnati unable to provide reliable offensive production. But this game represents an opportunity for one club to find its footing and build some much-needed rhythm as April rolls on. With Brady Singer taking the hill for the Reds and Elvin Rodríguez expected to start for Milwaukee, the matchup is primed to showcase one of the Reds’ biggest early bright spots against a Brewers pitcher still trying to settle in. Singer’s start to the 2025 season has been a beacon of hope for the Reds. He enters this game with a 1–0 record and a sparkling 0.00 ERA, having displayed dominant command and poise in his season debut. His mix of a heavy sinker and developing slider has proven effective against both right- and left-handed hitters, allowing him to pitch deep into games and minimize bullpen exposure. That could be critical for Cincinnati, as their bullpen has already shown signs of wear, struggling to hold narrow leads or keep games within reach when the offense falters. Milwaukee, meanwhile, counters with Rodríguez, who is looking to bounce back after a rough first start in which he surrendered runs early and struggled to find rhythm.

With an ERA hovering around 9.00, Rodríguez will be facing pressure to keep the Brewers in the game long enough for their lineup to go to work. If he can’t give them at least five solid innings, the bullpen will need to shoulder the load, which hasn’t been consistent to start the season either. On the offensive side, the Brewers have enjoyed flashes of productivity from key contributors like Sal Frelick and Brice Turang. Frelick has hit .321 through the first week of play and sets the tone from the top of the lineup with a disciplined approach and sneaky speed. Turang has provided power and clutch hitting, already notching two home runs and six RBIs. Milwaukee’s offensive game plan revolves around manufacturing runs, putting pressure on defenses, and taking advantage of runners in scoring position—a strategy that has worked when they’ve avoided long scoring droughts. The Reds, by contrast, have leaned heavily on Elly De La Cruz and Matt McLain to jumpstart the offense. De La Cruz leads the team with eight RBIs, while McLain has already homered three times, but the lack of support around them has left the lineup vulnerable. Cincinnati’s inability to cash in when runners reach base has stalled several promising innings, and unless their supporting cast steps up, the pressure will continue to mount on their top hitters. Saturday’s game is a critical checkpoint for both teams. For the Brewers, a win means securing a key series and building momentum at home; for the Reds, it’s a chance to steal a road victory, support their ace, and finally put together a complete performance that could shift the tone of their slow start.

Cincinnati Reds MLB Preview

The Cincinnati Reds head into their April 5, 2025 showdown with the Milwaukee Brewers desperate for a course correction after a frustrating stretch that has seen them drop four consecutive games. The club’s early-season struggles have been amplified by offensive stagnation—scoring just six total runs during that four-game skid—and repeated failure to cash in with runners in scoring position. For a team brimming with exciting young talent and managed by seasoned skipper Terry Francona, expectations were high heading into the season. But inconsistency at the plate, mental lapses in the field, and mounting bullpen issues have hampered their ability to finish games or play from behind effectively. With their record slipping and the surging Brewers pulling away early in the division standings, Saturday’s contest becomes pivotal for Cincinnati to stop the bleeding and get back into competitive form. Brady Singer provides a glimmer of optimism for the Reds on the mound. The right-hander, acquired in the offseason, has looked sharp in his 2025 debut, entering this contest with a perfect 1–0 record and an unblemished 0.00 ERA. Singer’s strength lies in his ability to generate ground balls with a heavy sinker and frustrate hitters with late-breaking off-speed pitches when working ahead in counts. His success in Kansas City carried over well into Cincinnati, and with the Brewers being a contact-oriented team rather than a slugging powerhouse, he’s well-positioned to attack the zone and pitch to weak contact. The challenge, however, is that Singer will need to go deep into the game, as Cincinnati’s bullpen has lacked reliability in recent outings. Long relievers have failed to hold narrow leads or prevent blow-ups, often forcing Francona to burn through arms early in the series. Singer’s efficiency and command will thus be critical if the Reds want to stabilize the game from the first pitch.

Offensively, the Reds have yet to find a consistent rhythm. While young phenom Elly De La Cruz continues to show flashes of brilliance—leading the team in RBIs with eight and displaying elite baserunning—he’s often been left stranded due to the lineup’s inability to extend innings. Matt McLain, who has three home runs, has done his part in terms of power, but outside of these two, the rest of the batting order has underwhelmed. Veteran bats like Jake Fraley and Spencer Steer have yet to heat up, and their inability to consistently get on base has left the team pressing for big hits rather than trusting in sequential offense. The upcoming matchup with Elvin Rodriguez, who holds a 9.00 ERA, presents a rare opportunity to break out of their funk—assuming they approach at-bats with patience and discipline, especially early in counts. If they can get to Rodriguez and force the Brewers into their bullpen by the fifth inning, the Reds have a real chance to flip the momentum. Defensively, Cincinnati’s lapses have come at the worst possible times—poor relay throws, dropped double-play balls, and hesitation on routine plays. These small mistakes have added up to big innings for their opponents. While the athleticism is there, especially with De La Cruz and McLain up the middle, the execution has to improve. Against a disciplined Milwaukee club that feasts on extra opportunities, Cincinnati must play cleaner, more aggressive defense. This game could very well be the swing point in their early season. If they can get six-plus quality innings from Singer, jump on a struggling Rodriguez, and finally tighten up the fundamentals, the Reds might finally put an end to their losing skid and reignite their 2025 campaign.

The Cincinnati Reds are set to face the Milwaukee Brewers on April 5, 2025, at American Family Field in Milwaukee, Wisconsin, with the first pitch scheduled for 7:10 PM ET. This matchup marks the third game in a four-game series between these National League Central division rivals. Cincinnati vs Milwaukee AI Prediction: Free MLB Betting Insights for Apr 05. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Milwaukee Brewers MLB Preview

The Milwaukee Brewers enter their April 5, 2025 home matchup against the Cincinnati Reds with confidence and momentum, having won four straight games and covered the spread in each of them. This strong early performance has positioned them favorably within the NL Central, and their ability to win close, low-scoring games has become a defining characteristic of the team’s resilience and focus. Under new manager Pat Murphy, the Brewers have leaned into a fundamentally sound, contact-driven brand of baseball, capitalizing on situational hitting and steady pitching. With Cincinnati arriving in a slump, Milwaukee has a prime opportunity to keep rolling, especially as their lineup continues to find rhythm and their pitching staff tightens its grip on opponents. Saturday’s matchup presents an important chance to build consistency and strengthen their home dominance at American Family Field. Elvin Rodriguez will take the mound for the Brewers, looking to bounce back from a rough season debut in which he posted a 9.00 ERA across a short outing. Rodriguez, acquired for his upside and swing-and-miss potential, has yet to deliver on his full promise but remains a projectable arm with the ability to turn a corner. His fastball-changeup combo is most effective when he’s ahead in counts, and he’ll need to establish the inside part of the plate early to disrupt Cincinnati’s timing. The Reds have been in an offensive funk, which could work to Rodriguez’s advantage—if he can limit early walks and work through the lineup cleanly once or twice, he may finally settle into a groove.

The Brewers’ bullpen has been reliable in recent games, anchored by the likes of Joel Payamps and Elvis Peguero, with closer Trevor Megill handling ninth-inning duties confidently. That safety net allows the Brewers to be aggressive with Rodriguez while minimizing long-term risk if he falters early. Milwaukee’s offense has been a pleasant surprise. While not overpowering, the Brewers have excelled at producing timely hits and sustaining pressure on opposing pitchers. Sal Frelick has emerged as the team’s most consistent performer, hitting .321 and delivering in clutch situations with a mature, all-fields approach. Brice Turang has provided the power, already slugging two home runs and leading the team in RBIs. Add in Christian Yelich’s veteran presence and improved at-bats, and the Brewers’ lineup has taken on a well-rounded identity. Though they lack the raw slugging of some NL rivals, Milwaukee’s offense works counts, advances runners, and thrives in high-contact scenarios—traits that match up well against a Reds team struggling both on the mound and in the field. With Rodriguez on the bump, early run support will be critical, and the Brewers’ patient approach may wear down Brady Singer if he doesn’t maintain his command. Defensively, Milwaukee has been crisp and efficient. Their infield, led by Turang and Willy Adames, is athletic and instinctive, turning double plays and cutting off balls in the gaps with precision. The outfield, headlined by Frelick and Garrett Mitchell, brings both range and arm strength, discouraging aggressive baserunning. The team’s defensive consistency has allowed them to stay competitive even when run production has been limited. Against a Reds team desperate for a win, the Brewers must maintain their composure, trust their process, and continue executing the fundamentals. A win would extend their streak, solidify their position in the division standings, and further establish that Milwaukee’s 2025 roster, while unassuming on paper, is built to win gritty, intelligent baseball games.

Cincinnati vs. Milwaukee Prop Picks (AI)

AI algorithm Remi is pouring through loads of stats on each player. In fact, anytime the Reds and Brewers play there’s always several intriguing trends to key in on. Not to mention games played at American Family Field in Apr rarely follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: E. De La Cruz over 0.5 Total Bases.

Cincinnati vs. Milwaukee Prediction (AI)

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Remi, our AI sports algorithm, has been pouring over mountains of data from every simulation between the Reds and Brewers and using recursive machine learning and impressive AI to boil down the data to a single cover probability.

Interestingly enough, the data has been most focused on the unproportionally assigned emphasis human bettors tend to put on player performance factors between a Reds team going up against a possibly healthy Brewers team. We’ve found the true game analytics might reflect a moderate lean against one Vegas line specifically.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI Cincinnati vs Milwaukee picks, computer picks Reds vs Brewers, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
MLB 9/26 DET@BOS UNLOCK THIS PICK 5 EXECUTIVE Locked EXECUTIVE
MLB 9/26 BAL@NYY UNLOCK THIS PICK 4 INTEL Locked INTEL
MLB 9/26 ARI@SD UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
MLB 9/26 NYM@MIA UNLOCK THIS PICK 1 INTEL Locked INTEL
MLB 9/26 NYM@MIA GET FREE PICK NOW 1
MLB 9/26 COL@SF UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Reds Betting Trends

The Reds have struggled against the spread (ATS) recently, failing to cover in their last four games. Their offense has been notably underperforming, averaging just 1.5 runs per game during this stretch.

Brewers Betting Trends

Conversely, the Brewers have been successful ATS, covering in their last four games. They’ve managed to win close contests, with three of these victories decided by two runs or fewer.

Reds vs. Brewers Matchup Trends

The Brewers’ recent ATS success is highlighted by their ability to win tight games, showcasing resilience in high-pressure situations. Meanwhile, the Reds’ offensive struggles have contributed to their ATS shortcomings, emphasizing the importance of generating runs to stay competitive.

Cincinnati vs. Milwaukee Game Info

Cincinnati vs Milwaukee starts on April 05, 2025 at 7:10 PM EST.

Venue: American Family Field.

Spread: Milwaukee +1.5
Moneyline: Cincinnati -116, Milwaukee -104
Over/Under: 8

Cincinnati: (2-6)  |  Milwaukee: (4-4)

Remi's searched hard and found the best prop for this matchup: E. De La Cruz over 0.5 Total Bases.. Prices move—always shop for the best number.

The Brewers’ recent ATS success is highlighted by their ability to win tight games, showcasing resilience in high-pressure situations. Meanwhile, the Reds’ offensive struggles have contributed to their ATS shortcomings, emphasizing the importance of generating runs to stay competitive.

CIN trend: The Reds have struggled against the spread (ATS) recently, failing to cover in their last four games. Their offense has been notably underperforming, averaging just 1.5 runs per game during this stretch.

MIL trend: Conversely, the Brewers have been successful ATS, covering in their last four games. They’ve managed to win close contests, with three of these victories decided by two runs or fewer.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Cincinnati vs. Milwaukee Odds

Remi is pouring through loads of data points on each team. In fact, anytime the Cincinnati vs Milwaukee trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme travel distance can often follow normal, predictable patterns.

Cincinnati vs Milwaukee Opening Odds

CIN Moneyline: -116
MIL Moneyline: -104
CIN Spread: -1.5
MIL Spread: +1.5
Over/Under: 8

Cincinnati vs Milwaukee Live Odds

Games PTS ML SPR O/U
Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
Orioles
Yankees
+192
-235
+1.5 (-110)
-1.5 (-110)
O 9 (+100)
U 9 (-120)
Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
 
-178
 
-1.5 (+115)
O 9.5 (+100)
U 9.5 (-120)
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
+135
-160
+1.5 (-160)
-1.5 (+135)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:06PM
White Sox
Nationals
+100
-120
+1.5 (-205)
-1.5 (+170)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
+192
-235
+1.5 (-110)
-1.5 (-110)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
-130
+110
-1.5 (+130)
+1.5 (-155)
O 8 (-120)
U 8 (+100)
Sep 27, 2025 4:11PM EDT
Detroit Tigers
Boston Red Sox
9/27/25 4:11PM
Tigers
Red Sox
+110
-130
+1.5 (-190)
-1.5 (+158)
O 9 (+100)
U 9 (-120)
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
+175
-210
+1.5 (-120)
-1.5 (+100)
O 8.5 (-115)
U 8.5 (-105)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+115
-135
+1.5 (-190)
-1.5 (+158)
O 7.5 (-120)
U 7.5 (+100)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+150
-178
+1.5 (-145)
-1.5 (+122)
O 8 (-110)
U 8 (-110)
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
+122
-145
+1.5 (-190)
-1.5 (+158)
O 7 (-120)
U 7 (+100)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+118
-140
+1.5 (-190)
-1.5 (+158)
O 7.5 (-115)
U 7.5 (-105)
Sep 27, 2025 9:39PM EDT
Houston Astros
Los Angeles Angels
9/27/25 9:39PM
Astros
Angels
-145
+122
-1.5 (+115)
+1.5 (-135)
O 9 (-110)
U 9 (-110)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+110
-130
+1.5 (-205)
-1.5 (+170)
O 7 (-120)
U 7 (+100)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
+100
-120
+1.5 (-195)
-1.5 (+162)
O 10 (-110)
U 10 (-110)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Cincinnati Reds vs. Milwaukee Brewers on April 05, 2025 at American Family Field.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS
CIN@ARI KEBRYAN HAYES STRIKEOUTS UNDER 0.5 56.2% 6 WIN
LAD@SD SD +110 50.9% 6 WIN