White Sox vs. Tigers
Prediction, Odds & Props
Apr 05 | MLB AI Picks
Updated: 2025-04-03T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Chicago White Sox are set to face the Detroit Tigers on April 5, 2025, at Comerica Park in Detroit, Michigan. This American League Central matchup features two teams aiming to improve their standings early in the season.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Apr 05, 2025
Start Time: 1:10 PM EST​
Venue: Comerica Park​
Tigers Record: (3-4)
White Sox Record: (2-5)
OPENING ODDS
CHW Moneyline: +183
DET Moneyline: -222
CHW Spread: +1.5
DET Spread: -1.5
Over/Under: 7.5
CHW
Betting Trends
- As of April 5, 2025, the Chicago White Sox have an Against The Spread (ATS) record of 2-0-0, indicating they have covered the spread in both of their games this season.
DET
Betting Trends
- The Detroit Tigers currently hold an ATS record of 0-1, suggesting they failed to cover the spread in their only game this season.
MATCHUP TRENDS
- In their recent head-to-head matchups during the 2024 season, the Tigers and White Sox had varying results. For instance, on September 27, 2024, the Tigers were favored with a moneyline of -200, and they won the game 4-1, covering the spread. Conversely, on September 28, 2024, the Tigers were again favored with a moneyline of -225 but lost 4-0 to the White Sox, failing to cover.
CHW vs. DET
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: L. Robert over 0.5 Total Bases.
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Chicago White Sox vs Detroit Prediction & Odds:
Free MLB Betting Insights for 4/5/25
At 4–3 on the year, the Tigers have already picked up a series win over the Seattle Mariners and will look to build off that momentum against a division rival they’ve handled well in recent years. Jack Flaherty, making his second start of the season, delivered a solid first outing with 5.2 innings pitched, five strikeouts, and just two earned runs allowed on three hits. The Tigers are optimistic that Flaherty, now fully healthy, can reclaim the form that made him a breakout ace in St. Louis a few years ago. At the plate, Detroit is benefiting from standout performances by Riley Greene, who went 5-for-13 with two home runs and two doubles in his last series, and Spencer Torkelson, who’s showing signs of becoming the middle-of-the-order threat the club envisioned. Injuries to Gleyber Torres and Matt Vierling have thinned the lower half of the lineup, but the Tigers’ improved plate discipline and situational hitting have helped offset that. Defensively, they’ve been sharp, with strong fundamentals and few mental lapses. Manager A.J. Hinch has shown confidence in his bullpen, rotating relievers effectively in close games and managing pitch counts wisely. Against a sputtering White Sox team, Detroit has an opportunity not only to secure a series win but to continue building a competitive rhythm that could make them a dark horse in the AL Central. Overall, this matchup features two teams in contrasting phases of their development. The White Sox are searching for answers amid lineup underperformance and mounting pressure, while the Tigers appear to be coalescing around their young core and new acquisitions. The outcome of this game could hinge on whether the White Sox can finally string together offensive production to back another promising start from Cannon—or if the Tigers, behind a steady Flaherty and timely hitting, can continue to assert themselves as a rising threat in the division. With early-season momentum and morale on the line, Saturday’s clash offers far more than just a notch in the standings—it could serve as a turning point for both clubs.
just gonna scooch in right here if you don’t mind pic.twitter.com/WhGLjkLDdH
— Chicago White Sox (@whitesox) April 4, 2025
Chicago White Sox White Sox MLB Preview
The Chicago White Sox travel to Comerica Park to face the Detroit Tigers on April 5, 2025, with cautious optimism and a desire to continue shaking off the shadows of a disappointing 2024 season. After an offseason focused on refining fundamentals, developing young talent, and building around a leaner, more versatile roster, the White Sox have started the new campaign on the right foot with a 2-0 record both straight up and against the spread (ATS). While it’s still early, the signs point toward a group more disciplined at the plate, more focused on defense, and more consistent on the mound. With an American League Central that remains wide open in the early stages, Chicago knows every divisional matchup matters—especially against a Tigers team that has been trying to climb back into contention in similar fashion. For the White Sox, this road game is an opportunity not only to maintain their momentum but to make an early statement that they are not the same team that underperformed last year. Jonathan Cannon will take the hill for the White Sox, making his second appearance of the season after a very promising debut in which he tossed five scoreless innings. The right-hander displayed poise beyond his years in that outing, using a mix of fastballs, sliders, and changeups to induce weak contact while limiting free passes. Though Cannon is still developing into a full-time starter, early flashes suggest he has the mental makeup and control to hold down a mid-rotation role. He’ll be tasked with neutralizing a Tigers lineup that includes heavy hitters like Spencer Torkelson and Riley Greene, both of whom can punish mistakes over the plate. Cannon’s key to success will be working ahead in counts, keeping the ball down in the zone, and not letting Detroit’s more dangerous hitters beat him early in at-bats.
If he can get through the lineup twice with minimal damage, the bullpen—featuring Gregory Santos, Aaron Bummer, and José Ruiz—should be able to close the door. Offensively, the White Sox are relying on the emergence of a few key bats to sustain early-season energy. Andrew Vaughn has stepped into a leadership role in the lineup, bringing a balanced approach and the ability to hit to all fields. Luis Robert Jr., the club’s most explosive player, remains a constant threat with his ability to turn any pitch into an extra-base hit. The team’s approach at the plate has looked more deliberate, with fewer strikeouts and better situational hitting—two areas that were glaring weaknesses in 2024. The bottom of the order, featuring players like Oscar Colás and Braden Shewmake, will need to contribute consistently if the White Sox are to extend rallies and wear down opposing starters like Jack Flaherty. Defensively, the White Sox have placed a renewed emphasis on fundamentals. With cleaner infield coordination and more aggressive outfield play, the early signs suggest a unit that’s committed to reducing unearned runs and converting outs more efficiently. Manager Pedro Grifol’s influence is becoming more visible, particularly in how the team manages tight games and executes small-ball strategies. While the season is still young, road games like this will define whether Chicago’s improvements are sustainable or simply a short-term surge. A win in Detroit would not only validate their approach but help solidify the identity of a team looking to re-establish itself as a playoff contender.

Credit: USA TODAY/IMAGN
Detroit Tigers MLB Preview
The Detroit Tigers enter their April 5, 2025 matchup against the Chicago White Sox at Comerica Park looking to recover from an early stumble and assert themselves as a contender in the American League Central. With a 1-1 start to the season and a 0-1 ATS record, the Tigers have shown flashes of promise but also areas of concern that need immediate attention. Playing at home provides a key opportunity to build momentum and set the tone for a long season ahead. After narrowly missing postseason contention in 2024, Detroit made offseason moves to bolster both their rotation and lineup. With young core pieces maturing and veteran leadership in place, the Tigers believe they’re positioned to take the next step. However, games against divisional opponents like the White Sox carry added weight, as early wins could be crucial when standings tighten later in the year. Starting pitcher Jack Flaherty will be tasked with setting the tone on the mound for the Tigers. Signed in the offseason to add veteran stability to the rotation, Flaherty made his Detroit debut earlier this week with a solid outing—tossing 5 2/3 innings, allowing two runs, and striking out five. His ability to mix speeds and change eye levels makes him a challenging opponent, particularly for aggressive lineups like Chicago’s. The key for Flaherty will be command; when he’s locating his fastball and staying ahead in counts, he limits damage and induces soft contact. However, inconsistency has crept into his game in recent seasons, and the Tigers need him to emerge as a dependable presence in the rotation. Against a White Sox team that can generate offense quickly through their top order, Flaherty’s early innings will be especially critical.
Offensively, Detroit will look to capitalize on Spencer Torkelson’s hot start. Torkelson, coming off a breakout 2024 season, continues to showcase power and improved plate discipline, already batting .340 with five home runs to his name. Alongside him, Riley Greene provides a dynamic spark with his left-handed bat and speed on the basepaths. The middle of the Tigers’ order has shown the ability to create scoring opportunities, but the bottom half has been inconsistent—a trend that dates back to last season. For Detroit to break games open and put pressure on opposing pitchers, they’ll need greater production from the likes of Matt Vierling and Andy Ibáñez. Manager A.J. Hinch has emphasized a more aggressive offensive philosophy this season, and executing that vision will require patience at the plate, timely base running, and capitalizing on mistakes. Defensively, the Tigers have looked sharper in the early going, particularly in the infield where improved chemistry between Javier Báez and Colt Keith has been noticeable. The outfield, anchored by Greene and Parker Meadows, boasts good range and arm strength, which could prove vital against a White Sox team that thrives on extra-base hits. Detroit’s bullpen, an area of concern in past seasons, has performed admirably so far, with relievers like Shelby Miller and Tyler Holton providing crucial outs in the later innings. If the Tigers can receive a strong start from Flaherty, limit defensive miscues, and get production throughout the lineup, they’ll have a solid chance to earn a statement win at home. This early-season contest presents an important litmus test for a team that believes it’s ready to compete—not just against the White Sox, but in the broader playoff picture.
W for the home crowd. 🧡 pic.twitter.com/0k6vTXCJgu
— Detroit Tigers (@tigers) April 4, 2025
Chicago White Sox vs. Detroit Prop Picks (AI)
Chicago White Sox vs. Detroit Prediction (AI)

Remi, our AI sports algorithm, has been pouring over mountains of data from every facet between the White Sox and Tigers and using recursive machine learning and impressive AI to boil down the data to a single cover probability.
Interestingly enough, the data has been most watching on the unproportionally assigned emphasis emotional bettors often put on coaching factors between a White Sox team going up against a possibly strong Tigers team. It appears the true game analytics might reflect a strong lean against one Vegas line specifically.
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Below is our current AI Chicago White Sox vs Detroit picks, computer picks White Sox vs Tigers, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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White Sox Betting Trends
As of April 5, 2025, the Chicago White Sox have an Against The Spread (ATS) record of 2-0-0, indicating they have covered the spread in both of their games this season.
Tigers Betting Trends
The Detroit Tigers currently hold an ATS record of 0-1, suggesting they failed to cover the spread in their only game this season.
White Sox vs. Tigers Matchup Trends
In their recent head-to-head matchups during the 2024 season, the Tigers and White Sox had varying results. For instance, on September 27, 2024, the Tigers were favored with a moneyline of -200, and they won the game 4-1, covering the spread. Conversely, on September 28, 2024, the Tigers were again favored with a moneyline of -225 but lost 4-0 to the White Sox, failing to cover.
Chicago White Sox vs. Detroit Game Info
What time does Chicago White Sox vs Detroit start on April 05, 2025?
Chicago White Sox vs Detroit starts on April 05, 2025 at 1:10 PM EST.
Where is Chicago White Sox vs Detroit being played?
Venue: Comerica Park.
What are the opening odds for Chicago White Sox vs Detroit?
Spread: Detroit -1.5
Moneyline: Chicago White Sox +183, Detroit -222
Over/Under: 7.5
What are the records for Chicago White Sox vs Detroit?
Chicago White Sox: (2-5) Â |Â Detroit: (3-4)
What is the AI best bet for Chicago White Sox vs Detroit?
Remi's searched hard and found the best prop for this matchup: L. Robert over 0.5 Total Bases.. Prices move—always shop for the best number.
What are Chicago White Sox vs Detroit trending bets?
In their recent head-to-head matchups during the 2024 season, the Tigers and White Sox had varying results. For instance, on September 27, 2024, the Tigers were favored with a moneyline of -200, and they won the game 4-1, covering the spread. Conversely, on September 28, 2024, the Tigers were again favored with a moneyline of -225 but lost 4-0 to the White Sox, failing to cover.
What are Chicago White Sox trending bets?
CHW trend: As of April 5, 2025, the Chicago White Sox have an Against The Spread (ATS) record of 2-0-0, indicating they have covered the spread in both of their games this season.
What are Detroit trending bets?
DET trend: The Detroit Tigers currently hold an ATS record of 0-1, suggesting they failed to cover the spread in their only game this season.
Where can I find AI Picks for Chicago White Sox vs Detroit?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
Chicago White Sox vs. Detroit Odds
Remi is pouring through tons of data points on each team. In fact, anytime the Chicago White Sox vs Detroit trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme temps can often follow normal, predictable patterns.
Chicago White Sox vs Detroit Opening Odds
CHW Moneyline:
+183 DET Moneyline: -222
CHW Spread: +1.5
DET Spread: -1.5
Over/Under: 7.5
Chicago White Sox vs Detroit Live Odds
Games | PTS | ML | SPR | O/U | |
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In Progress
Colorado Rockies
San Francisco Giants
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Rockies
Giants
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3
4
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+680
-1400
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-1.5 (+1000)
+1.5 (-3700)
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O 7.5 (+234)
U 7.5 (-326)
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In Progress
New York Mets
Miami Marlins
In Progress
Mets
Marlins
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3
0
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-5000
+1300
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-2.5 (-300)
+2.5 (+210)
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O 3.5 (-138)
U 3.5 (+104)
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In Progress
Detroit Tigers
Boston Red Sox
In Progress
Tigers
Red Sox
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2
1
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-700
+440
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-1.5 (+270)
+1.5 (-400)
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O 3.5 (-102)
U 3.5 (-130)
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In Progress
Chicago White Sox
Washington Nationals
In Progress
White Sox
Nationals
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4
2
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-390
+280
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-1.5 (-158)
+1.5 (+118)
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O 9.5 (+128)
U 9.5 (-172)
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In Progress
Minnesota Twins
Philadelphia Phillies
In Progress
Twins
Phillies
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1
0
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+136
-174
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+1.5 (-166)
-1.5 (+124)
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O 9.5 (+108)
U 9.5 (-144)
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Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
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–
–
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+116
-134
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+1.5 (-184)
-1.5 (+152)
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O 8 (-110)
U 8 (-110)
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Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
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–
–
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+144
-172
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+1.5 (-142)
-1.5 (+118)
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O 8 (-118)
U 8 (-104)
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Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
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–
–
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+128
-152
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+1.5 (-182)
-1.5 (+150)
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O 7.5 (+104)
U 7.5 (-128)
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Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
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–
–
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+130
-154
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+1.5 (-166)
-1.5 (+138)
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O 7.5 (-105)
U 7.5 (-115)
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Sep 27, 2025 9:39PM EDT
Houston Astros
Los Angeles Angels
9/27/25 9:39PM
Astros
Angels
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–
–
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-146
+124
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-1.5 (+112)
+1.5 (-134)
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O 9 (-108)
U 9 (-112)
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Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
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–
–
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+100
-118
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+1.5 (-215)
-1.5 (+176)
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O 7 (-118)
U 7 (-104)
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Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
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–
–
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+100
-118
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-1.5 (+150)
+1.5 (-182)
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O 10 (-114)
U 10 (-106)
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Sep 28, 2025 3:06PM EDT
Baltimore Orioles
New York Yankees
9/28/25 3:06PM
Orioles
Yankees
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–
–
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+144
-172
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+1.5 (-146)
-1.5 (+122)
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O 9 (-122)
U 9 (+100)
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Sep 28, 2025 3:06PM EDT
Colorado Rockies
San Francisco Giants
9/28/25 3:06PM
Rockies
Giants
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–
–
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+270
-335
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+1.5 (+112)
-1.5 (-134)
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O 7.5 (-110)
U 7.5 (-110)
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Sep 28, 2025 3:06PM EDT
Minnesota Twins
Philadelphia Phillies
9/28/25 3:06PM
Twins
Phillies
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–
–
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+180
-215
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+1.5 (-130)
-1.5 (+108)
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O 8 (-122)
U 8 (+100)
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MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Chicago White Sox White Sox vs. Detroit Tigers on April 05, 2025 at Comerica Park.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
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   LEAN |    %WIN |    UNITS | RESULT |
---|---|---|---|---|
ARI@SD | SD -131 | 57.3% | 4 | WIN |
DET@BOS | BOS -115 | 56.4% | 5 | WIN |
NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
LAA@COL | COL +108 | 50.5% | 3 | WIN |
TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
KC@PHI | PHI -130 | 58.3% | 4 | WIN |
LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
KC@CLE | KC -104 | 52.0% | 3 | WIN |
CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |
PHI@NYM | OVER 8.5 | 55.6% | 4 | LOSS |
LAA@TEX | LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS | 54.1% | 4 | LOSS |
KC@CHW | KC -109 | 54.2% | 4 | WIN |
SD@SEA | DYLAN CEASE OVER 16.5 OUTS | 53.9% | 3 | LOSS |
SD@SEA | UNDER 8.5 | 54.4% | 4 | LOSS |
MIN@TOR | JOE RYAN UNDER 2.5 EARNED RUNS | 54.1% | 4 | LOSS |
SF@MIL | MIL +100 | 54.0% | 6 | LOSS |
TOR@MIA | MIA +1.5 | 62.0% | 6 | WIN |
CHC@LAA | OVER 9.5 | 54.9% | 4 | LOSS |
BOS@NYY | CARLOS RODON UNDER 4.5 HITS ALLOWED | 54.2% | 4 | WIN |
KC@DET | DET -115 | 56.1% | 5 | WIN |
CHC@LAA | LAA +1.5 | 57.6% | 5 | LOSS |