Reds vs. Brewers
Prediction, Odds & Props
Apr 04 | MLB AI Picks
Updated: 2025-04-02T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Cincinnati Reds will face the Milwaukee Brewers on April 4, 2025, at American Family Field in Milwaukee, Wisconsin. This matchup features two National League Central teams looking to establish early-season momentum.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.
GAME INFO
Date: Apr 04, 2025
Start Time: 8:10 PM EST
Venue: American Family Field
Brewers Record: (3-4)
Reds Record: (2-5)
OPENING ODDS
CIN Moneyline: -103
MIL Moneyline: -116
CIN Spread: -1.5
MIL Spread: +1.5
Over/Under: 8
CIN
Betting Trends
- In the 2024 season, the Reds finished with a 78-84 record. Their performance against the spread (ATS) was mixed, with some stretches where they struggled to cover, particularly in away games.
MIL
Betting Trends
- The Brewers concluded the 2024 season with an 89-73 record. They were generally strong ATS at home, often exceeding expectations with timely hitting and solid pitching.
MATCHUP TRENDS
- The Brewers have covered the spread in 60% of their last 50 games as home favorites. The Reds have failed to cover the spread in 55% of their last 50 games as away underdogs. The total has gone over in 65% of games between these two teams in Milwaukee over the past three seasons.
CIN vs. MIL
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: E. De La Cruz over 0.5 Total Bases.
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Cincinnati vs Milwaukee Prediction & Odds:
Free MLB Betting Insights for 4/4/25
On the mound, the Brewers are in a good position, as they feature one of the most well-rounded rotations in the National League. Freddy Peralta, who has been one of the team’s most consistent starters over the past few seasons, will anchor the rotation. Peralta, with his electric fastball and strikeout stuff, has the potential to be a game-changer, and he will look to set the tone for the Brewers’ pitching staff in this season opener. Alongside him, the Brewers can rely on Brandon Woodruff, who is known for his excellent command and ability to pitch deep into games. The Brewers’ pitching staff is bolstered further by a bullpen that has historically been one of the best in baseball, with arms like Devin Williams and Josh Hader providing reliable closers for high-leverage situations. For the Reds, the pitching staff will be one of the key components to their success in 2025. Hunter Greene, who has the potential to be one of the top pitchers in the league, will be tasked with leading the Reds’ rotation. After a solid 2024 season, Greene will need to continue to improve his control and command to match up against the Brewers’ lineup. Alongside him, Nick Lodolo and Nick Martinez provide depth and promise to the Reds’ pitching staff, and their performances will be critical for the team’s chances of competing in the competitive NL Central. The Reds’ ability to limit big innings and keep the Brewers’ offense at bay will be key to their success in this series. Offensively, the Reds will rely on Jonathan India and Tyler Stephenson, both of whom have the ability to generate runs and create offensive opportunities. India, with his ability to get on base and drive in runs, will be a key figure for the Reds at the top of the order. Meanwhile, Stephenson, one of the top young catchers in the league, will continue to provide power and consistency in the middle of the lineup. Additionally, the Reds will need contributions from other emerging players, including rookie sensation Junior Caminero, who has the potential to be a breakout star in 2025. This game will be an exciting early-season test for both teams. The Brewers will look to use their depth and experience to assert their dominance, while the Reds aim to prove that their young talent is ready to compete with the league’s best. As both teams continue to solidify their identities for the season, the outcome of this game will have lasting implications for their early-season goals and positioning in the National League Central.
Final from Milwaukee: pic.twitter.com/nxy8B9XFHm
— Cincinnati Reds (@Reds) April 4, 2025
Cincinnati Reds MLB Preview
The Cincinnati Reds enter the 2025 season with a fresh sense of optimism, despite a challenging 2024 campaign where they finished with a 78-84 record. After a period of rebuilding, the Reds are now focused on developing their young talent and becoming more competitive in the National League Central. The team’s goal is to break out of the mid-tier of the division and make a push for the playoffs, building on the strengths they developed last year and improving on areas of need. With a combination of promising young players and veteran leadership, the Reds are poised to challenge the established teams in the division like the Brewers and Cardinals. At the core of the Reds’ 2025 hopes is their pitching staff, which has the potential to become a strength if the young arms continue to develop. Hunter Greene, who is one of the top young pitchers in the game, will anchor the rotation. Greene, known for his high-velocity fastball and strikeout ability, showed promise last season and is expected to take another step forward in 2025. His performance will be key to the Reds’ success, as they’ll need a frontline starter to compete against the top pitchers in the division. Joining Greene in the rotation is Nick Lodolo, another promising young arm who has shown flashes of brilliance. The Reds will also rely on the veteran presence of Nick Martinez to stabilize the back end of the rotation. If the Reds’ pitching staff can perform at a high level and take advantage of its depth, they could become one of the league’s surprise teams in 2025. Offensively, the Reds will rely on a mixture of young talent and veteran hitters to generate runs. Jonathan India, a key player for the Reds, will be looked upon to lead the offense from the leadoff spot. India, with his ability to get on base and provide both speed and power, is one of the team’s most dynamic players. He’ll be complemented by catcher Tyler Stephenson, who has proven to be a reliable hitter in the middle of the order.
The addition of Junior Caminero, a highly touted young player, is expected to make an immediate impact. Caminero’s raw talent and potential give the Reds an exciting prospect to develop into a key piece of their offense. With veterans like Joey Votto and Will Myers providing steady contributions, the Reds’ lineup has the potential to surprise teams that overlook them. The Reds’ defense will need to improve in 2025 to become more competitive in the division. While they have strong defensive players like India at second base and Stephenson behind the plate, consistency will be key across the board. The outfield, with players like Aristides Aquino and Jake Fraley, has the potential to be solid, but ensuring they don’t give up extra-base hits will be vital when facing teams with strong offenses like the Brewers. The Reds will need to avoid making errors and rely on their defense to help their pitchers stay out of trouble. As the away team, the Reds face a tough challenge in Milwaukee, but they will be looking to make an early statement in 2025. The Brewers, as the division champions, will be a formidable opponent, but the Reds will aim to use their young arms and offense to compete with the established team. If the Reds can get contributions from their key players, particularly on the mound, they’ll have a real chance to make this game competitive. This matchup against a postseason-caliber team like the Brewers is an important early test for the Reds, and a strong performance could set the tone for the rest of their season.
Credit: USA TODAY/IMAGN
Milwaukee Brewers MLB Preview
The Milwaukee Brewers come into the 2025 season with high expectations, looking to defend their NL Central title after a strong 2024 campaign where they finished with an 89-73 record. As one of the more consistent teams in the National League over the past few years, the Brewers have become accustomed to competing for a playoff spot and are determined to take the next step in 2025. With a well-rounded roster, a solid pitching staff, and an offense led by established stars, the Brewers are set to challenge for another postseason berth. This season, their goal is to continue to improve on their strengths while addressing the few weaknesses that kept them from advancing further in the postseason last year. Offensively, the Brewers are led by veteran Christian Yelich, whose performance over the past couple of seasons has been a bit inconsistent due to injuries, but still remains a key player in the middle of the lineup. Yelich is one of the most complete players in baseball when healthy, capable of providing both power and average, and is expected to be a driving force for the Brewers’ offense. Alongside him is shortstop Willy Adames, who has proven to be a major offensive contributor. Adames brings both power and stability to the lineup and is one of the most underrated shortstops in baseball. The Brewers also made a significant offseason acquisition in William Contreras, a catcher with a strong bat, further improving their offensive depth. With hitters like Rowdy Tellez, Jesse Winker, and the speedy Kolten Wong providing support, the Brewers’ lineup has a solid mix of power, contact, and speed, making them a tough team to pitch to.
On the mound, the Brewers boast one of the most formidable pitching staffs in the league. Freddy Peralta, who is coming off a solid season, will anchor the rotation. Peralta is known for his strikeout stuff and ability to overpower hitters with his fastball, but consistency and keeping his command will be key in matching up against the high-powered offenses in the NL. Alongside him, Brandon Woodruff and Corbin Burnes will provide the Brewers with a dynamic 1-2-3 punch at the top of the rotation. Both Woodruff and Burnes have shown elite stuff and the ability to handle the pressure of big games. The Brewers’ pitching staff is also supported by a deep bullpen that has historically been one of the best in the league. With Devin Williams leading the charge in the late innings and Josh Hader providing a dominant closer role, the Brewers’ bullpen is poised to handle high-leverage situations and secure wins in tight contests. Defensively, the Brewers continue to excel, with a solid infield featuring Adames, Wong, and Tellez at first base. Yelich’s glove and leadership in the outfield, paired with the reliable arm strength and range of other outfielders, complete the Brewers’ defensive unit. The Brewers’ defense has improved over the years, and their ability to avoid mistakes and make key plays in high-leverage situations will be essential as they look to contend again in 2025. As the home team, the Brewers will be hoping to take full advantage of Globe Life Field, a stadium where they have been successful in recent years. With their deep and balanced roster, the Brewers are favorites to win this opening game against the Cincinnati Reds, and they’ll be looking to set the tone for a strong 2025 season. They have the pitching, power, and defensive prowess to contend with the best, and as they take on the Reds, the Brewers will be aiming to establish themselves as one of the top teams in the National League from the very start of the season. This home opener is a chance to make a statement and further their pursuit of another division title.
Our man bounced back in a big way 😤@Cortes_1210 pic.twitter.com/TI62Yxsy0S
— Milwaukee Brewers (@Brewers) April 4, 2025
Cincinnati vs. Milwaukee Prop Picks (AI)
Cincinnati vs. Milwaukee Prediction (AI)
Remi, our AI sports genius, has been pouring over mountains of data from every facet between the Reds and Brewers and using recursive machine learning and impressive AI to examine the data to a single cover probability.
Oddly enough, we’ve seen the AI has been most fixated on the trending emphasis knucklehead sportsbettors often put on player performance factors between a Reds team going up against a possibly deflated Brewers team. In reality, the true game analytics appear to reflect a slight lean against one Vegas line in particular.
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Below is our current AI Cincinnati vs Milwaukee picks, computer picks Reds vs Brewers, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
|---|---|---|---|---|---|---|
| ACTIVE PICKS LOCKED - SEE NOW | ||||||
These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.
Reds Betting Trends
In the 2024 season, the Reds finished with a 78-84 record. Their performance against the spread (ATS) was mixed, with some stretches where they struggled to cover, particularly in away games.
Brewers Betting Trends
The Brewers concluded the 2024 season with an 89-73 record. They were generally strong ATS at home, often exceeding expectations with timely hitting and solid pitching.
Reds vs. Brewers Matchup Trends
The Brewers have covered the spread in 60% of their last 50 games as home favorites. The Reds have failed to cover the spread in 55% of their last 50 games as away underdogs. The total has gone over in 65% of games between these two teams in Milwaukee over the past three seasons.
Cincinnati vs. Milwaukee Game Info
What time does Cincinnati vs Milwaukee start on April 04, 2025?
Cincinnati vs Milwaukee starts on April 04, 2025 at 8:10 PM EST.
Where is Cincinnati vs Milwaukee being played?
Venue: American Family Field.
What are the opening odds for Cincinnati vs Milwaukee?
Spread: Milwaukee +1.5
Moneyline: Cincinnati -103, Milwaukee -116
Over/Under: 8
What are the records for Cincinnati vs Milwaukee?
Cincinnati: (2-5) | Milwaukee: (3-4)
What is the AI best bet for Cincinnati vs Milwaukee?
Remi's searched hard and found the best prop for this matchup: E. De La Cruz over 0.5 Total Bases.. Prices move—always shop for the best number.
What are Cincinnati vs Milwaukee trending bets?
The Brewers have covered the spread in 60% of their last 50 games as home favorites. The Reds have failed to cover the spread in 55% of their last 50 games as away underdogs. The total has gone over in 65% of games between these two teams in Milwaukee over the past three seasons.
What are Cincinnati trending bets?
CIN trend: In the 2024 season, the Reds finished with a 78-84 record. Their performance against the spread (ATS) was mixed, with some stretches where they struggled to cover, particularly in away games.
What are Milwaukee trending bets?
MIL trend: The Brewers concluded the 2024 season with an 89-73 record. They were generally strong ATS at home, often exceeding expectations with timely hitting and solid pitching.
Where can I find AI Picks for Cincinnati vs Milwaukee?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
Cincinnati vs. Milwaukee Odds
AI algorithm Remi is pouring through loads of data on each team. In fact, anytime the Cincinnati vs Milwaukee trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme hostile environments almost always follow normal, predictable betting trends.
Cincinnati vs Milwaukee Opening Odds
CIN Moneyline:
-103 MIL Moneyline: -116
CIN Spread: -1.5
MIL Spread: +1.5
Over/Under: 8
Cincinnati vs Milwaukee Live Odds
| Games | PTS | ML | SPR | O/U | |
|---|---|---|---|---|---|
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Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
Orioles
Yankees
|
–
–
|
+196
-240
|
+1.5 (-105)
-1.5 (-115)
|
O 9 (-105)
U 9 (-115)
|
|
|
Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
|
–
–
|
-178
|
-1.5 (+115)
|
O 9.5 (+100)
U 9.5 (-120)
|
|
|
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
|
–
–
|
+135
-160
|
+1.5 (-155)
-1.5 (+130)
|
O 8.5 (-105)
U 8.5 (-115)
|
|
|
Sep 27, 2025 4:05PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:05PM
White Sox
Nationals
|
–
–
|
+100
-120
|
+1.5 (-205)
-1.5 (+170)
|
O 8.5 (-115)
U 8.5 (-105)
|
|
|
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
|
–
–
|
+196
-240
|
+1.5 (-110)
-1.5 (-110)
|
O 8 (-105)
U 8 (-115)
|
|
|
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
|
–
–
|
-130
+110
|
-1.5 (+130)
+1.5 (-155)
|
O 8 (-115)
U 8 (-105)
|
|
|
Sep 27, 2025 4:11PM EDT
Detroit Tigers
Boston Red Sox
9/27/25 4:11PM
Tigers
Red Sox
|
–
–
|
+110
-130
|
+1.5 (-190)
-1.5 (+158)
|
O 9 (+100)
U 9 (-120)
|
|
|
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
|
–
–
|
+175
-210
|
+1.5 (-120)
-1.5 (+100)
|
O 8.5 (-115)
U 8.5 (-105)
|
|
|
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
|
–
–
|
+115
-135
|
+1.5 (-190)
-1.5 (+158)
|
O 7.5 (-120)
U 7.5 (+100)
|
|
|
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
|
–
–
|
+150
-178
|
+1.5 (-145)
-1.5 (+122)
|
O 8 (-110)
U 8 (-110)
|
|
|
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
|
–
–
|
+122
-145
|
+1.5 (-190)
-1.5 (+158)
|
O 7 (-120)
U 7 (+100)
|
|
|
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
|
–
–
|
+118
-140
|
+1.5 (-190)
-1.5 (+158)
|
O 7.5 (-115)
U 7.5 (-105)
|
|
|
Sep 27, 2025 9:39PM EDT
Houston Astros
Los Angeles Angels
9/27/25 9:39PM
Astros
Angels
|
–
–
|
-140
+118
|
-1.5 (+115)
+1.5 (-135)
|
O 9 (-110)
U 9 (-110)
|
|
|
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
|
–
–
|
+100
-120
|
+1.5 (-220)
-1.5 (+180)
|
O 7 (-120)
U 7 (+100)
|
|
|
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
|
–
–
|
+100
-120
|
+1.5 (-195)
-1.5 (+162)
|
O 10 (-115)
U 10 (-105)
|
MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Cincinnati Reds vs. Milwaukee Brewers on April 04, 2025 at American Family Field.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
| MLB |
LEAN | %WIN | UNITS | RESULT |
|---|---|---|---|---|
| ARI@SD | SD -131 | 57.3% | 4 | WIN |
| DET@BOS | BOS -115 | 56.4% | 5 | WIN |
| NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
| HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
| NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
| STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
| KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
| MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
| MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
| WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
| LAA@COL | COL +108 | 50.5% | 3 | WIN |
| TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
| SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
| NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
| MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
| MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
| SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
| PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
| NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
| KC@PHI | PHI -130 | 58.3% | 4 | WIN |
| LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
| NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
| KC@CLE | KC -104 | 52.0% | 3 | WIN |
| CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
| WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
| LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
| TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
| SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
| SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
| MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
| NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
| TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
| TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
| ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
| PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
| ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
| SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
| CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
| NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |
| PHI@NYM | OVER 8.5 | 55.6% | 4 | LOSS |
| LAA@TEX | LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS | 54.1% | 4 | LOSS |
| KC@CHW | KC -109 | 54.2% | 4 | WIN |
| SD@SEA | DYLAN CEASE OVER 16.5 OUTS | 53.9% | 3 | LOSS |
| SD@SEA | UNDER 8.5 | 54.4% | 4 | LOSS |
| MIN@TOR | JOE RYAN UNDER 2.5 EARNED RUNS | 54.1% | 4 | LOSS |
| SF@MIL | MIL +100 | 54.0% | 6 | LOSS |
| TOR@MIA | MIA +1.5 | 62.0% | 6 | WIN |
| CHC@LAA | OVER 9.5 | 54.9% | 4 | LOSS |
| BOS@NYY | CARLOS RODON UNDER 4.5 HITS ALLOWED | 54.2% | 4 | WIN |
| KC@DET | DET -115 | 56.1% | 5 | WIN |
| CHC@LAA | LAA +1.5 | 57.6% | 5 | LOSS |