Red Sox vs. Orioles
Prediction, Odds & Props
Mar 31 | MLB AI Picks
Updated: 2025-03-29T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Baltimore Orioles will host the Boston Red Sox on March 31, 2025, at Oriole Park at Camden Yards in Baltimore, Maryland. Both teams aim to commence their seasons with a strong performance in this American League East division matchup.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Mar 31, 2025
Start Time: 2:35 PM EST​
Venue: Oriole Park at Camden Yards​
Orioles Record: (2-2)
Red Sox Record: (1-3)
OPENING ODDS
BOS Moneyline: +121
BAL Moneyline: -145
BOS Spread: +1.5
BAL Spread: -1.5
Over/Under: 9.5
BOS
Betting Trends
- As this is the season opener, there are no recent Against The Spread (ATS) statistics available for the Red Sox.
BAL
Betting Trends
- Similarly, with the season just beginning, no recent ATS data is available for the Orioles.
MATCHUP TRENDS
- Historically, matchups between the Red Sox and Orioles have been competitive, often resulting in closely contested games, which may influence betting considerations.
BOS vs. BAL
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: S. Newcomb under 3.5 Pitcher Strikeouts.
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Boston vs Baltimore Prediction & Odds:
Free MLB Betting Insights for 3/31/25
The familiarity between the division rivals adds an extra layer of intrigue to this Opening Day matchup. Key factors to watch in this game include the performance of the starting pitchers, the effectiveness of bullpen strategies, and the ability of hitters to capitalize on scoring opportunities. Defensive plays and base-running decisions will also play crucial roles in determining the game’s outcome. Fans can anticipate a competitive and engaging game as both teams strive to start the 2025 season on a high note. The outcome of this Opening Day matchup may provide early insights into the strengths and areas for improvement for both the Red Sox and the Orioles as they navigate the challenges of the new season.
Fitts holding it down. 👊 pic.twitter.com/kJU9lYO2LZ
— Red Sox (@RedSox) March 30, 2025
Boston Red Sox MLB Preview
The Boston Red Sox enter the 2025 MLB season opener against the Baltimore Orioles on March 31 at Oriole Park at Camden Yards with renewed optimism and heightened expectations. Following a strategic offseason focused on bolstering their roster, the Red Sox are eager to set a strong tone in the highly competitive American League East. Under the leadership of veteran manager Alex Cora, the team combines seasoned experience with youthful promise, aiming to reclaim their status as perennial contenders and erase memories of recent struggles. A key offseason acquisition for Boston was third baseman Alex Bregman, whose arrival significantly upgrades the team’s offensive capabilities and infield defense. Bregman, a proven talent with consistent power, elite plate discipline, and postseason experience, immediately strengthens the middle of the Red Sox lineup. His veteran presence, along with existing stars like Rafael Devers and Masataka Yoshida, creates a formidable trio capable of challenging even the league’s top pitchers. Devers, in particular, remains a cornerstone of Boston’s offense, coming off consecutive seasons where he displayed impressive consistency, power, and clutch hitting. Yoshida adds versatility and reliable contact hitting, providing balance to the lineup and creating challenging matchups for opposing pitchers. Boston’s outfield, anchored by dynamic talents such as Jarren Duran and Alex Verdugo, emphasizes speed, athleticism, and defensive range. Duran continues to evolve as a key catalyst, showcasing elite speed on the base paths and growing confidence at the plate. Verdugo, a fan favorite known for his hustle and consistency, contributes valuable hitting depth and a strong arm in right field. Their defensive prowess will be particularly important in spacious ballparks such as Camden Yards, helping the pitching staff limit extra-base hits and run production.
On the pitching front, Boston made significant moves to bolster their rotation, highlighted by the acquisition of hard-throwing left-hander Garrett Crochet. Crochet, whose combination of high velocity and effective breaking pitches makes him a challenging matchup for hitters, immediately slots into the upper tier of Boston’s rotation. His arrival, alongside veterans like Brayan Bello and Tanner Houck, provides the Red Sox with a balanced and diverse pitching staff capable of competing consistently within a challenging division. Bello, in particular, showed great promise last season with his improved command and consistency, and his continued growth will be vital to Boston’s postseason aspirations. The bullpen, often a decisive factor in tightly contested divisional games, has also seen upgrades. Veteran closer Kenley Jansen anchors the relief corps, bringing experience and reliability in high-pressure situations. Supporting him, setup relievers John Schreiber and Chris Martin provide depth and versatility, offering Cora strategic flexibility to handle late-inning situations effectively. Maintaining leads late in games, especially on the road against division rivals like Baltimore, will be crucial for Boston’s success throughout the season. Defensively, the Red Sox emphasize strong fundamentals, especially within the infield. With Bregman at third, Devers handling first base more frequently, and Trevor Story providing veteran leadership up the middle, Boston boasts a sturdy defensive unit capable of limiting errors and supporting pitchers effectively. Defensive consistency will be especially important in a competitive environment like Camden Yards, where minimizing defensive miscues can greatly impact game outcomes. Overall, the Red Sox approach their season opener with optimism, having addressed several critical needs through strategic moves and player development. Their offensive depth, improved pitching rotation, and defensive reliability position them well to challenge the Orioles and set a positive trajectory for the season. A victory on Opening Day would not only provide valuable early-season momentum but also reinforce the team’s confidence as they pursue their ultimate goal of contending deep into October.

Credit: USA TODAY/IMAGN
Baltimore Orioles MLB Preview
The Baltimore Orioles enter the 2025 MLB season with a focus on nurturing their young talent and building upon the foundations laid in previous years. Under the guidance of manager Brandon Hyde, the Orioles aim to leverage their home-field advantage at Oriole Park at Camden Yards to kickstart their campaign positively against the Boston Red Sox on March 31. Offensively, the Orioles are anchored by emerging stars who have shown promise in their development. The lineup features a blend of speed and power, with players capable of impacting the game through various facets. The team’s approach at the plate emphasizes patience and discipline, aiming to increase on-base percentages and create scoring opportunities. The pitching staff, while youthful, has the potential to surprise opponents. The starting rotation comprises pitchers who have gained valuable experience and are expected to take on more significant roles this season. The bullpen, a critical component in close games, has been a focus during the offseason, with efforts made to enhance depth and reliability. Defensively, the Orioles prioritize fundamentals and cohesion. The infield and outfield units have worked extensively during spring training to improve communication and execution, aiming to reduce errors and support the pitching staff effectively.
As the Orioles prepare to face the Red Sox, several factors will be pivotal to their success. The performance of the starting pitcher in navigating Boston’s lineup, the ability of the offense to capitalize on scoring opportunities, and the effectiveness of bullpen management will all play crucial roles. Additionally, maintaining defensive solidity and executing strategic base running will contribute to the team’s competitiveness. The coaching staff has emphasized the importance of starting the season with intensity and focus. Preparations have included in-depth analysis of the Red Sox’s tendencies, allowing for the development of tailored game plans. The team’s readiness to adapt and respond to in-game developments will be a testament to their preparation and resilience. Hosting the Red Sox at Oriole Park offers the Orioles an opportunity to leverage home-field advantage. The support of the home crowd provides an energizing atmosphere that can inspire elevated performance. Engaging fans early in the season and building momentum at home are integral components of the Orioles’ strategy for success in 2025. In summary, the Baltimore Orioles approach the 2025 season opener with a blend of optimism and determination. The matchup against the Boston Red Sox serves as an early test of their progress and an opportunity to demonstrate their potential in the competitive landscape of the American League East.
This time tomorrow. pic.twitter.com/LQlIjPGxt9
— Baltimore Orioles (@Orioles) March 30, 2025
Boston vs. Baltimore Prop Picks (AI)
Boston vs. Baltimore Prediction (AI)

Remi, our AI sports algorithm, has been pouring over millions of data from every facet between the Red Sox and Orioles and using recursive machine learning and industry leading AI to crunch the data to a single cover probability.
Interestingly enough, the data has been most watching on the unproportionally assigned weight knucklehead sportsbettors regularly put on Boston’s strength factors between a Red Sox team going up against a possibly unhealthy Orioles team. We’ve found the true game analytics appear to reflect a slight lean against one Vegas line specifically.
Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.
Below is our current AI Boston vs Baltimore picks, computer picks Red Sox vs Orioles, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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MLB | 9/26 | DET@BOS | UNLOCK THIS PICK | 5 |
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MLB | 9/26 | BAL@NYY | UNLOCK THIS PICK | 4 |
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MLB | 9/26 | ARI@SD | UNLOCK THIS PICK | 4 |
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MLB | 9/26 | NYM@MIA | UNLOCK THIS PICK | 1 |
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MLB | 9/26 | NYM@MIA | GET FREE PICK NOW | 1 | – | |
MLB | 9/26 | COL@SF | UNLOCK THIS PICK | 0 |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.
Red Sox Betting Trends
As this is the season opener, there are no recent Against The Spread (ATS) statistics available for the Red Sox.
Orioles Betting Trends
Similarly, with the season just beginning, no recent ATS data is available for the Orioles.
Red Sox vs. Orioles Matchup Trends
Historically, matchups between the Red Sox and Orioles have been competitive, often resulting in closely contested games, which may influence betting considerations.
Boston vs. Baltimore Game Info
What time does Boston vs Baltimore start on March 31, 2025?
Boston vs Baltimore starts on March 31, 2025 at 2:35 PM EST.
Where is Boston vs Baltimore being played?
Venue: Oriole Park at Camden Yards.
What are the opening odds for Boston vs Baltimore?
Spread: Baltimore -1.5
Moneyline: Boston +121, Baltimore -145
Over/Under: 9.5
What are the records for Boston vs Baltimore?
Boston: (1-3) Â |Â Baltimore: (2-2)
What is the AI best bet for Boston vs Baltimore?
Remi's searched hard and found the best prop for this matchup: S. Newcomb under 3.5 Pitcher Strikeouts.. Prices move—always shop for the best number.
What are Boston vs Baltimore trending bets?
Historically, matchups between the Red Sox and Orioles have been competitive, often resulting in closely contested games, which may influence betting considerations.
What are Boston trending bets?
BOS trend: As this is the season opener, there are no recent Against The Spread (ATS) statistics available for the Red Sox.
What are Baltimore trending bets?
BAL trend: Similarly, with the season just beginning, no recent ATS data is available for the Orioles.
Where can I find AI Picks for Boston vs Baltimore?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
Boston vs. Baltimore Odds
AI algorithm Remi is pouring through tons of data on each player. In fact, anytime the Boston vs Baltimore trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme hostile environments seemingly never follow normal, predictable patterns.
Boston vs Baltimore Opening Odds
BOS Moneyline:
+121 BAL Moneyline: -145
BOS Spread: +1.5
BAL Spread: -1.5
Over/Under: 9.5
Boston vs Baltimore Live Odds
Games | PTS | ML | SPR | O/U | |
---|---|---|---|---|---|
Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
Orioles
Yankees
|
–
–
|
+190
-235
|
+1.5 (-110)
-1.5 (-110)
|
O 8.5 (-120)
U 8.5 (+100)
|
|
Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
|
–
–
|
-175
|
-1.5 (+115)
|
O 9.5 (-105)
U 9.5 (-115)
|
|
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
|
–
–
|
+130
-155
|
+1.5 (-155)
-1.5 (+130)
|
O 8.5 (-110)
U 8.5 (-110)
|
|
Sep 27, 2025 4:06PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:06PM
White Sox
Nationals
|
–
–
|
+100
-120
|
-1.5 (+165)
+1.5 (-200)
|
O 8.5 (-110)
U 8.5 (-110)
|
|
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
|
–
–
|
+185
-225
|
+1.5 (-110)
-1.5 (-110)
|
O 8 (-105)
U 8 (-115)
|
|
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
|
–
–
|
-130
+110
|
-1.5 (+125)
+1.5 (-150)
|
O 8.5 (-105)
U 8.5 (-115)
|
|
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
|
–
–
|
+170
-205
|
+1.5 (-120)
-1.5 (+100)
|
O 8.5 (-115)
U 8.5 (-105)
|
|
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
|
–
–
|
+125
-150
|
+1.5 (-180)
-1.5 (+150)
|
O 8 (-105)
U 8 (-115)
|
|
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
|
–
–
|
+140
-170
|
+1.5 (-155)
-1.5 (+130)
|
O 8 (-110)
U 8 (-110)
|
|
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
|
–
–
|
+135
-165
|
+1.5 (-180)
-1.5 (+150)
|
O 7 (-120)
U 7 (+100)
|
|
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
|
–
–
|
+115
-140
|
+1.5 (-190)
-1.5 (+155)
|
O 7.5 (-120)
U 7.5 (+100)
|
|
Sep 27, 2025 9:39PM EDT
Houston Astros
Los Angeles Angels
9/27/25 9:39PM
Astros
Angels
|
–
–
|
-165
+135
|
-1.5 (+105)
+1.5 (-125)
|
O 9 (+100)
U 9 (-120)
|
|
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
|
–
–
|
+100
-120
|
-1.5 (+170)
+1.5 (-205)
|
O 7.5 (-110)
U 7.5 (-110)
|
|
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
|
–
–
|
+100
-120
|
-1.5 (+150)
+1.5 (-180)
|
O 10 (-110)
U 10 (-110)
|
MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Boston Red Sox vs. Baltimore Orioles on March 31, 2025 at Oriole Park at Camden Yards.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
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   LEAN |    %WIN |    UNITS | RESULT |
---|---|---|---|---|
NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
LAA@COL | COL +108 | 50.5% | 3 | WIN |
TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
KC@PHI | PHI -130 | 58.3% | 4 | WIN |
LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
KC@CLE | KC -104 | 52.0% | 3 | WIN |
CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |
PHI@NYM | OVER 8.5 | 55.6% | 4 | LOSS |
LAA@TEX | LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS | 54.1% | 4 | LOSS |
KC@CHW | KC -109 | 54.2% | 4 | WIN |
SD@SEA | DYLAN CEASE OVER 16.5 OUTS | 53.9% | 3 | LOSS |
SD@SEA | UNDER 8.5 | 54.4% | 4 | LOSS |
MIN@TOR | JOE RYAN UNDER 2.5 EARNED RUNS | 54.1% | 4 | LOSS |
SF@MIL | MIL +100 | 54.0% | 6 | LOSS |
TOR@MIA | MIA +1.5 | 62.0% | 6 | WIN |
CHC@LAA | OVER 9.5 | 54.9% | 4 | LOSS |
BOS@NYY | CARLOS RODON UNDER 4.5 HITS ALLOWED | 54.2% | 4 | WIN |
KC@DET | DET -115 | 56.1% | 5 | WIN |
CHC@LAA | LAA +1.5 | 57.6% | 5 | LOSS |
CIN@ARI | KEBRYAN HAYES STRIKEOUTS UNDER 0.5 | 56.2% | 6 | WIN |
LAD@SD | SD +110 | 50.9% | 6 | WIN |