Angels vs. White Sox
Prediction, Odds & Props
Mar 29 | MLB AI Picks

Updated: 2025-03-27T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Los Angeles Angels will face the Chicago White Sox on March 29, 2025, at Guaranteed Rate Field in Chicago. Both teams aim to rebound from challenging 2024 seasons and establish early momentum in this interleague matchup.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Mar 29, 2025

Start Time: 2:10 PM EST​

Venue: Rate Field​

White Sox Record: (1-0)

Angels Record: (0-1)

OPENING ODDS

LAA Moneyline: -163

CHW Moneyline: +138

LAA Spread: -1.5

CHW Spread: +1.5

Over/Under: 8

LAA
Betting Trends

  • The Angels struggled on the road in 2024, covering the spread in only 31% of their away games.

CHW
Betting Trends

  • The White Sox had a low home cover rate in 2024, covering the spread in just 24% of home games.

MATCHUP TRENDS

  • Despite their overall struggles, the White Sox managed a 4-2 record against the Angels in the 2024 season.

LAA vs. CHW
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: Y. Moncada over 0.5 Total Bases.

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Los Angeles Angels vs Chicago White Sox Prediction & Odds:
Free MLB Betting Insights for 3/29/25

The upcoming game between the Los Angeles Angels and the Chicago White Sox on March 29, 2025, at Guaranteed Rate Field, presents an opportunity for both teams to demonstrate improvements following disappointing 2024 campaigns. The Angels concluded the previous season with a 63-99 record, while the White Sox endured a historically poor 41-121 finish. This early-season contest is crucial for both clubs to establish momentum and assess the effectiveness of their offseason adjustments. The Angels have made strategic moves to bolster their roster, focusing on enhancing both their lineup and pitching staff. Offensively, they aim to improve run production, which was inconsistent last season. The addition of players like Jorge Soler is expected to provide the necessary power and depth to support the lineup. On the mound, the Angels have revamped their rotation, with Tyler Anderson and Kyle Hendricks expected to provide stability and experience. These changes reflect the organization’s commitment to addressing the shortcomings that plagued them in 2024. Conversely, the White Sox are in a rebuilding phase, focusing on developing young talent and restructuring their roster. The promotion of prospects like Edgar Quero and Colson Montgomery signals a shift towards a youth-oriented approach.

However, the team faces challenges, including injuries to key players such as Mike Tauchman and Josh Rojas, which may impact their early-season performance. The White Sox’s ability to integrate new talent and overcome these obstacles will be critical in determining their competitiveness this season. Historically, the White Sox held a 4-2 advantage over the Angels in their 2024 matchups, suggesting a competitive edge. However, with both teams undergoing significant changes, past performance may not be indicative of future results. The Angels’ revamped lineup and pitching staff could pose new challenges for the White Sox, while Chicago’s infusion of young talent may bring unpredictability to their gameplay. This game also serves as a platform for individual players to showcase their development. For the Angels, monitoring the performance of their new acquisitions and assessing the effectiveness of their pitching rotation will be key. The White Sox will be keen to evaluate the readiness of their prospects and the resilience of their lineup amidst injuries. In summary, the March 29 matchup between the Los Angeles Angels and the Chicago White Sox is more than just an early-season game; it is a litmus test for both organizations’ offseason strategies and a glimpse into their potential trajectories for the 2025 season. Fans can anticipate a game filled with strategic plays, emerging talents, and the unfolding narratives of two teams striving to redefine themselves in Major League Baseball.

Los Angeles Angels Angels MLB Preview

The Los Angeles Angels head into their March 29, 2025, matchup against the Chicago White Sox with optimism and a clear mission to turn the page on a disappointing 2024 season that saw them finish 63-99 and well out of playoff contention, despite having superstar talent on the roster. After another offseason of restructuring, the Angels are focused on redefining their identity and achieving consistency across both offense and pitching, two areas that plagued them throughout last year. The lineup, which struggled with injuries and run production in 2024, now features notable reinforcements such as slugger Jorge Soler, who brings proven power from the middle of the order and is expected to play a crucial role in revitalizing the offense. Soler’s presence will complement the efforts of Mike Trout—still one of baseball’s most feared hitters when healthy—as well as Brandon Drury and Logan O’Hoppe, both of whom offer reliable production and versatility. The Angels will also look for further growth from young players like Nolan Schanuel and Zach Neto, two highly regarded prospects who are being counted on to contribute consistently at the major league level. On the pitching side, the Angels made it a priority to solidify their starting rotation, which was one of the weakest in the league last year, adding veteran Kyle Hendricks to provide stability and leadership alongside returning lefty Tyler Anderson. Hendricks, known for his pinpoint control and cerebral approach to pitching, is expected to eat innings and keep games competitive while helping guide the club’s younger arms. Anderson, who had an up-and-down 2024, is looking for a bounce-back year and has reportedly improved his command and off-speed pitch effectiveness heading into this season.

The bullpen, anchored by closer Carlos Estévez and key setup man Matt Moore, has shown flashes of excellence and will be a focal point for manager Ron Washington, who was brought in during the offseason to bring experience, leadership, and accountability to a team that has long lacked cohesion. Washington’s managerial presence is already being felt in camp and the clubhouse, as he implements a more aggressive base-running philosophy and emphasizes fundamental defensive play—two areas where the Angels lagged behind in recent seasons. Entering this game against a rebuilding White Sox squad, the Angels have a valuable opportunity to stack early wins, test their revamped rotation, and let their offense find rhythm against a pitching staff still trying to find its footing. Though the Angels were just 31% ATS on the road last season, early matchups like this against struggling teams will be critical in setting the tone for a turnaround year. With Shohei Ohtani no longer in the organization, the Angels are determined to prove they can win with depth, experience, and contributions across the board rather than relying solely on generational talent. A strong showing against Chicago, particularly from their new-look lineup and starting pitching, would send a message that the Angels are serious about contending in 2025 and capable of exceeding expectations in a wide-open American League West.

The Los Angeles Angels will face the Chicago White Sox on March 29, 2025, at Guaranteed Rate Field in Chicago. Both teams aim to rebound from challenging 2024 seasons and establish early momentum in this interleague matchup. Los Angeles Angels vs Chicago White Sox AI Prediction: Free MLB Betting Insights for Mar 29. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Chicago White Sox White Sox MLB Preview

The Chicago White Sox enter the 2025 season with a focus on rebuilding and integrating new talent into their roster. Following a challenging 2024 season that saw them finish with a 41-121 record, the organization has made strategic moves to revitalize the team and set a foundation for future success. Offensively, the White Sox are looking to improve upon a lineup that struggled with consistency last year. The team has promoted top prospects such as Edgar Quero and Colson Montgomery, who are expected to bring fresh energy and potential to the batting order. These young players, alongside established figures like Luis Robert Jr., are anticipated to play pivotal roles in the team’s offensive strategy. However, injuries to key players, including Mike Tauchman and Josh Rojas, present early challenges that the team must navigate. Defensively, the White Sox are aiming for greater stability and cohesion. The integration of new coaching staff, including manager Sergio Santos and coaches Ángel Rosario and Jim Rickon, is part of the organization’s effort to instill a new culture and approach to the game.

The pitching rotation features a mix of promising talent and experienced players, with Jairo Iriarte and Nick Nastrini expected to contribute significantly. The bullpen includes prospects like Adisyn Coffey and Chase Plymell, who have shown potential in their development. Despite the challenges, there is a sense of optimism within the organization and among fans. The team’s focus on developing homegrown talent and making strategic acquisitions reflects a commitment to building a competitive team for the future. The upcoming game against the Los Angeles Angels provides an opportunity for the White Sox to showcase their progress and assess the effectiveness of their offseason strategies. In conclusion, the Chicago White Sox are in a transitional phase, emphasizing development and strategic planning. While immediate success may be tempered by the realities of rebuilding, the organization’s efforts are geared towards establishing a sustainable and competitive team in the coming seasons.

Los Angeles Angels vs. Chicago White Sox Prop Picks (AI)

Remi is pouring through tons of data on each line. In fact, anytime the Angels and White Sox play there’s always several intriguing observations to key in on. Not to mention games played at Rate Field in Mar rarely follow normal, predictable patterns.
Remi's searched hard and found the best prop for this matchup: Y. Moncada over 0.5 Total Bases.

Los Angeles Angels vs. Chicago White Sox Prediction (AI)

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Remi, our AI sports genius, has been pouring over exorbitant amounts of data from every facet between the Angels and White Sox and using recursive machine learning and impressive AI to examine the data to a single cover probability.

Oddly enough, we’ve seen the AI has been most keyed in on the linear correlation of emphasis emotional bettors often put on Chicago White Sox’s strength factors between a Angels team going up against a possibly healthy White Sox team. We’ve found the true game analytics appear to reflect a strong lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI Los Angeles Angels vs Chicago White Sox picks, computer picks Angels vs White Sox, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
MLB 9/26 DET@BOS UNLOCK THIS PICK 5 EXECUTIVE Locked EXECUTIVE
MLB 9/26 BAL@NYY UNLOCK THIS PICK 4 INTEL Locked INTEL
MLB 9/26 ARI@SD UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
MLB 9/26 NYM@MIA UNLOCK THIS PICK 1 INTEL Locked INTEL
MLB 9/26 NYM@MIA GET FREE PICK NOW 1
MLB 9/26 COL@SF UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Angels Betting Trends

The Angels struggled on the road in 2024, covering the spread in only 31% of their away games.

White Sox Betting Trends

The White Sox had a low home cover rate in 2024, covering the spread in just 24% of home games.

Angels vs. White Sox Matchup Trends

Despite their overall struggles, the White Sox managed a 4-2 record against the Angels in the 2024 season.

Los Angeles Angels vs. Chicago White Sox Game Info

Los Angeles Angels vs Chicago White Sox starts on March 29, 2025 at 2:10 PM EST.

Spread: Chicago White Sox +1.5
Moneyline: Los Angeles Angels -163, Chicago White Sox +138
Over/Under: 8

Los Angeles Angels: (0-1)  |  Chicago White Sox: (1-0)

Remi's searched hard and found the best prop for this matchup: Y. Moncada over 0.5 Total Bases.. Prices move—always shop for the best number.

Despite their overall struggles, the White Sox managed a 4-2 record against the Angels in the 2024 season.

LAA trend: The Angels struggled on the road in 2024, covering the spread in only 31% of their away games.

CHW trend: The White Sox had a low home cover rate in 2024, covering the spread in just 24% of home games.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Los Angeles Angels vs. Chicago White Sox Odds

Remi is pouring through tons of data on each player. In fact, anytime the Los Angeles Angels vs Chicago White Sox trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme temps can often follow normal, predictable patterns.

Los Angeles Angels vs Chicago White Sox Opening Odds

LAA Moneyline: -163
CHW Moneyline: +138
LAA Spread: -1.5
CHW Spread: +1.5
Over/Under: 8

Los Angeles Angels vs Chicago White Sox Live Odds

Games PTS ML SPR O/U
Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
Orioles
Yankees
+195
-218
+1.5 (-109)
-1.5 (-105)
O 8.5 (-124)
U 8.5 (+108)
Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
 
-168
 
-1.5 (+118)
O 9 (-119)
U 9 (+104)
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
+138
-152
+1.5 (-152)
-1.5 (+134)
O 8.5 (-113)
U 8.5 (-102)
Sep 27, 2025 4:06PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:06PM
White Sox
Nationals
+104
-115
+1.5 (-198)
-1.5 (+174)
O 8.5 (-107)
U 8.5 (-107)
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
+195
-218
+1.5 (-107)
-1.5 (-107)
O 8 (+101)
U 8 (-116)
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
-128
+116
-1.5 (+129)
+1.5 (-146)
O 8 (-112)
U 8 (-103)
Sep 27, 2025 4:11PM EDT
Detroit Tigers
Boston Red Sox
9/27/25 4:11PM
Tigers
Red Sox
+116
-128
+1.5 (-184)
-1.5 (+162)
O 9 (+107)
U 9 (-123)
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
+180
-200
+1.5 (-117)
-1.5 (+103)
O 8.5 (-107)
U 8.5 (-107)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+120
-132
+1.5 (-183)
-1.5 (+161)
O 7.5 (-120)
U 7.5 (+105)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+153
-169
+1.5 (-141)
-1.5 (+125)
O 8 (-102)
U 8 (-113)
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
+128
-141
+1.5 (-183)
-1.5 (+161)
O 7 (-118)
U 7 (+103)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+122
-135
+1.5 (-177)
-1.5 (+156)
O 7.5 (-113)
U 7.5 (-102)
Sep 27, 2025 9:39PM EDT
Houston Astros
Los Angeles Angels
9/27/25 9:39PM
Astros
Angels
-140
+127
-1.5 (+116)
+1.5 (-131)
O 9 (-107)
U 9 (-107)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+113
-125
+1.5 (-197)
-1.5 (+173)
O 7 (-116)
U 7 (+101)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
+104
-115
+1.5 (-190)
-1.5 (+166)
O 10 (-115)
U 10 (+100)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Los Angeles Angels Angels vs. Chicago White Sox White Sox on March 29, 2025 at Rate Field.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS
CIN@ARI KEBRYAN HAYES STRIKEOUTS UNDER 0.5 56.2% 6 WIN
LAD@SD SD +110 50.9% 6 WIN