Mets vs Astros Prediction — AI Finds CAN'T MISS MLB Lines & Props (Mar 27)

Updated: 2025-03-25T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The New York Mets will commence their 2025 MLB season by visiting the Houston Astros at Daikin Park on March 27, 2025, with the first pitch scheduled for 4:10 p.m. ET. Both teams aim to start the season strong, featuring notable roster changes and strategic adjustments.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Mar 27, 2025

Start Time: 4:10 PM EST​

Venue: Daikin Park​

Astros Record: (0-0)

Mets Record: (0-0)

OPENING ODDS

NYM Moneyline: +114

HOU Moneyline: -134

NYM Spread: +1.5

HOU Spread: -1.5

Over/Under: 8

NYM
Betting Trends

  • In the 2024 season, the Mets were underdogs in 75 games, winning 34 of those, resulting in a 45.3% success rate. When listed as underdogs with a moneyline of +110 or more, they had a 48.8% win rate (21-22).

HOU
Betting Trends

  • During the 2024 season, the Astros were favored in 119 games, securing victories in 67, which equates to a 56.3% success rate. When playing as moneyline favorites with odds of -131 or shorter, Houston had a 60.4% win rate (55-36).

MATCHUP TRENDS

  • The Astros have consistently performed well on Opening Day, winning their season opener in each of the past three years.

NYM vs. HOU
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: F. Lindor over 6 Fantasy Score.

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New York Mets vs Houston Prediction & Odds:
Free MLB Betting Insights for 3/27/25

The 2025 MLB season opener features an intriguing matchup between the New York Mets and the Houston Astros at Daikin Park. Both teams have undergone significant roster changes during the offseason, setting the stage for a compelling game. The Mets will send right-hander Clay Holmes to the mound for his first career Opening Day start. Holmes, transitioning from a bullpen role with the Yankees to a starting position with the Mets, has shown promise during Spring Training. His performance will be pivotal for the Mets, especially given the recent injuries to key pitchers Sean Manaea and Frankie Montas. Offensively, the Mets have bolstered their lineup with the acquisition of star outfielder Juan Soto, who signed a record-breaking $765 million contract. Soto joins a formidable batting order that includes Francisco Lindor and Pete Alonso, providing the Mets with a potent offensive threat. However, the team’s pitching depth remains a concern, with uncertainties surrounding the rotation due to injuries. The Astros will counter with left-hander Framber Valdez, making his fourth consecutive Opening Day start. Valdez has been a reliable ace for Houston, leading major league starters in wins over the past three seasons. His consistent performance and ability to handle high-pressure situations make him a formidable opponent for the Mets’ lineup.

Houston’s lineup features a mix of seasoned veterans and emerging talent. Notably, 22-year-old prospect Cam Smith will make his MLB debut in right field. Smith, acquired in the trade that sent Kyle Tucker to the Chicago Cubs, impressed during Spring Training with a .342 batting average and four home runs. His addition brings youthful energy and potential to the Astros’ offense. Betting odds favor the Astros, with a moneyline of -131, while the Mets are listed at +110. The over/under is set at 8 runs, suggesting expectations of a moderately low-scoring game. As the teams take the field, fans can anticipate a competitive game that may set the tone for their respective seasons. The Mets will look to leverage their revamped lineup and Holmes’ performance on the mound, while the Astros aim to capitalize on their home-field advantage and Valdez’s experience to secure a victory.

New York Mets Mets MLB Preview

The New York Mets begin the 2025 MLB season as one of the most compelling teams in baseball, combining a mix of star power, big-market pressure, and the fresh energy of a new-look roster under first-year manager Carlos Beltrán. After a disappointing 2024 campaign in which the Mets underperformed relative to their massive payroll and preseason expectations, team owner Steve Cohen and the front office aggressively retooled the roster. The centerpiece of the Mets’ offseason was the acquisition of superstar outfielder Juan Soto, who signed a jaw-dropping $765 million contract, the largest in MLB history. Soto brings an elite combination of power, patience, and postseason experience to the middle of the Mets’ lineup and is expected to transform the team’s offensive identity. Alongside franchise cornerstone Francisco Lindor and slugging first baseman Pete Alonso, the Mets now boast a formidable heart of the order capable of producing runs in bunches. The Mets open the season against the Houston Astros at Daikin Park, a team known for postseason excellence and one of the most balanced rosters in the league. New York’s Opening Day starter is Clay Holmes, who will make his first start in that role after transitioning from a late-inning relief role with the Yankees. Holmes was one of the most effective relievers in baseball over the past few seasons, and while his shift to the rotation comes with risk, early signs in spring training were encouraging. His pitch arsenal—featuring a heavy sinker and sharp slider—will be tested against Houston’s disciplined and powerful lineup. Injuries have impacted the Mets’ projected rotation, with both Sean Manaea and Frankie Montas beginning the year on the IL, so Holmes’ performance in this new role could be pivotal in determining the rotation’s stability in the opening months.

Defensively, the Mets have made strides toward improvement, adding outfield depth and committing to better infield positioning through analytics. Jeff McNeil remains a reliable option at second base, known for his high-contact approach and defensive versatility. At third, Brett Baty is expected to get an extended run to prove he’s the long-term answer, while Francisco Álvarez anchors the pitching staff from behind the plate. Álvarez flashed elite power last season and is continuing to develop his game-calling and pitch-framing skills. New York’s bullpen, anchored by veteran closer Edwin Díaz—who is returning after missing 2024 due to injury—looks much stronger. Díaz has shown that he still possesses elite velocity and swing-and-miss stuff, and he will be backed by Adam Ottavino, Brooks Raley, and newcomer Yimi García in high-leverage situations. Betting trends suggest the Mets were competitive as underdogs in 2024, winning 45.3% of games when in that role and nearly splitting matchups when listed with moneylines of +110 or more. Their retooled offense, combined with renewed focus on fundamentals under Beltrán’s leadership, makes them a potential surprise team in the National League. Facing Framber Valdez and the Astros on Opening Day presents a serious test, but if Soto, Lindor, and Alonso produce and Holmes can manage five solid innings, the Mets could make a powerful opening statement in their pursuit of postseason redemption in 2025.

The New York Mets will commence their 2025 MLB season by visiting the Houston Astros at Daikin Park on March 27, 2025, with the first pitch scheduled for 4:10 p.m. ET. Both teams aim to start the season strong, featuring notable roster changes and strategic adjustments. New York Mets vs Houston AI Prediction: Free MLB Betting Insights for Mar 27. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Houston Astros MLB Preview

The Houston Astros enter the 2025 MLB season with a blend of seasoned leadership and promising young talent, aiming to build upon their recent successes and maintain their status as contenders in the American League. Following a 2024 season that saw them reach the postseason but fall short in the Wild Card round, the Astros have made strategic roster adjustments to address key areas and bolster their competitiveness. A significant development for the Astros is the emergence of 22-year-old prospect Cam Smith, who has earned a spot on the Opening Day roster and will start in right field. Smith, acquired from the Chicago Cubs in the trade involving All-Star Kyle Tucker, has made a rapid ascent to the majors, having played only 32 minor league games before his promotion. During his brief minor league stint, Smith posted a .313 batting average with seven home runs, showcasing his offensive potential. His versatility allows him to play both third base and outfield positions, providing manager Joe Espada with valuable flexibility in lineup construction. The Astros’ infield remains a cornerstone of their success, with stalwarts like José Altuve and Alex Bregman providing leadership and consistent performance. Altuve, transitioning to a role that includes time in left field, continues to be a catalyst at the top of the lineup, while Bregman’s defensive prowess and offensive contributions solidify the left side of the infield. First baseman Christian Walker, acquired during the offseason, adds power to the lineup and is expected to be a key run producer. The outfield configuration features Jake Meyers in center field, with Chas McCormick providing depth and versatility off the bench. The integration of Cam Smith into the outfield mix is anticipated to enhance both offensive output and defensive coverage.

The Astros’ commitment to blending experienced players with emerging talent reflects their strategic approach to sustained competitiveness. On the mound, Framber Valdez anchors the starting rotation, bringing reliability and a proven track record to the staff. Valdez’s ability to deliver quality starts and manage high-leverage situations is instrumental to the team’s success. The bullpen remains a strength for the Astros, anchored by closer Ryan Pressly, who has been among the league’s most reliable relievers over the past few seasons. Pressly posted a 2.89 ERA with 31 saves in 2024 and continues to dominate with his sharp slider and fastball command. The setup corps includes Bryan Abreu, who emerged as a premier strikeout artist with a 1.75 ERA in high-leverage situations, and Rafael Montero, providing stability from the right side. The team also signed veteran lefty Andrew Chafin in the offseason to add a southpaw presence to the pen, bolstering their ability to handle late-game matchups. This depth allows new manager Joe Espada to manage innings more flexibly while protecting young arms from being overexposed early in the season. The Astros’ coaching staff has emphasized defensive efficiency and baserunning this spring, aiming to minimize the small mistakes that cost them several close games last season. Veteran catcher Martín Maldonado remains an elite pitch framer and defensive strategist behind the plate, guiding a staff that also includes Hunter Brown and J.P. France, both of whom are expected to grow into full-time roles. Espada, in his first year managing after years as Dusty Baker’s bench coach, has been praised for his communication, attention to detail, and progressive use of analytics. His familiarity with the roster provides continuity and trust, crucial for a team balancing veteran expectations and the emergence of younger players. Offensively, the Astros still possess one of the more dynamic lineups in the American League. Yordan Alvarez, the club’s most dangerous bat, returns after another dominant season in which he hit .306 with 37 home runs and 114 RBIs. His presence in the middle of the order is a nightmare for opposing pitchers, especially when paired with the disciplined and contact-heavy approach of Altuve and Bregman ahead of him. Christian Walker, acquired in a trade with Arizona, will slot into the cleanup role, bringing a consistent 30-home-run threat to the right side of the lineup. With Cam Smith providing a lefty spark and contributions expected from McCormick, Jeremy Peña, and young DH options like Joey Loperfido, the Astros’ offense is expected to be more balanced and less reliant on the long ball. Despite being edged out early in the 2024 postseason, the Astros remain one of the AL’s most complete rosters and are well-positioned to return to October with deeper aspirations. Their dominance on Opening Day, where they’ve won three straight season openers, reflects the organization’s culture of preparedness and consistency. Hosting the Mets to open 2025 gives them a platform to reassert that dominance. With Valdez on the mound, a reloaded batting order, and a strong bullpen at their disposal, Houston enters Opening Day as a calculated and confident favorite, focused not only on starting the season with a win, but also proving they remain a premier franchise in baseball. A convincing performance in front of the home crowd at Daikin Park would serve notice to the rest of the American League that the Astros are not done contending just yet.

New York Mets vs. Houston Prop Picks (AI)

AI algorithm Remi is pouring through mountains of stats on each player. In fact, anytime the Mets and Astros play there’s always several intriguing trends to key in on. Not to mention games played at Daikin Park in Mar rarely follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: F. Lindor over 6 Fantasy Score.

New York Mets vs. Houston Prediction (AI)

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Remi, our AI sports algorithm, has been pouring over mountains of data from every facet between the Mets and Astros and using recursive machine learning and cutting-edge AI to crunch the data to a single cover probability.

Oddly enough, we’ve seen the AI has been most watching on the growing factor human bettors tend to put on Houston’s strength factors between a Mets team going up against a possibly improved Astros team. We’ve found the true game analytics might reflect a moderate lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI New York Mets vs Houston picks, computer picks Mets vs Astros, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Mets Betting Trends

In the 2024 season, the Mets were underdogs in 75 games, winning 34 of those, resulting in a 45.3% success rate. When listed as underdogs with a moneyline of +110 or more, they had a 48.8% win rate (21-22).

Astros Betting Trends

During the 2024 season, the Astros were favored in 119 games, securing victories in 67, which equates to a 56.3% success rate. When playing as moneyline favorites with odds of -131 or shorter, Houston had a 60.4% win rate (55-36).

Mets vs. Astros Matchup Trends

The Astros have consistently performed well on Opening Day, winning their season opener in each of the past three years.

New York Mets vs. Houston Game Info

New York Mets vs Houston starts on March 27, 2025 at 4:10 PM EST.

Spread: Houston -1.5
Moneyline: New York Mets +114, Houston -134
Over/Under: 8

New York Mets: (0-0)  |  Houston: (0-0)

Remi's searched hard and found the best prop for this matchup: F. Lindor over 6 Fantasy Score.. Prices move—always shop for the best number.

The Astros have consistently performed well on Opening Day, winning their season opener in each of the past three years.

NYM trend: In the 2024 season, the Mets were underdogs in 75 games, winning 34 of those, resulting in a 45.3% success rate. When listed as underdogs with a moneyline of +110 or more, they had a 48.8% win rate (21-22).

HOU trend: During the 2024 season, the Astros were favored in 119 games, securing victories in 67, which equates to a 56.3% success rate. When playing as moneyline favorites with odds of -131 or shorter, Houston had a 60.4% win rate (55-36).

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

New York Mets vs. Houston Odds

Remi is pouring through tons of data points on each team. In fact, anytime the New York Mets vs Houston trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme temps almost always follow normal, predictable patterns.

New York Mets vs Houston Opening Odds

NYM Moneyline: +114
HOU Moneyline: -134
NYM Spread: +1.5
HOU Spread: -1.5
Over/Under: 8

New York Mets vs Houston Live Odds

Games PTS ML SPR O/U
Oct 19, 2025 8:04PM EDT
Seattle Mariners
Toronto Blue Jays
10/19/25 8:04PM
Mariners
Blue Jays
+107
-128
+1.5 (-195)
-1.5 (+165)
O 7.5 (-115)
U 7.5 (-105)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers New York Mets Mets vs. Houston Astros on March 27, 2025 at Daikin Park.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
TOR@SEA OVER 7 54.9% 3 WIN
LAD@MIL UNDER 7.5 56.6% 6 WIN
TOR@NYY OVER 8 54.9% 4 WIN
TOR@NYY CARLOS RODON OVER 1.5 TOTAL WALKS ALLOWED 53.3% 3 WIN
NYY@TOR OVER 7.5 54.8% 2 WIN
LAD@PHI OVER 7 53.8% 3 WIN
SD@CHC CHC -109 53.8% 3 WIN
SD@CHC OVER 7.5 54.5% 4 LOSS
SD@CHC CHC -111 54.8% 4 LOSS
CIN@LAD SHOHEI OHTANI OVER 1.5 BASES 53.5% 3 WIN
BOS@NYY OVER 7 53.8% 3 LOSS
CIN@LAD ELLY DE LA CRUZ OVER 0.5 BASES 54.4% 4 LOSS
ARI@SD SD -131 57.3% 4 WIN
DET@BOS BOS -115 56.4% 5 WIN
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN