Away Team
Record 5-1
Last 5 4-1 last five
ATS 4-2-0 ATS
Road 1-1 road
Standings
CFB Game Preview
Schedule
Kickoff Countdown
5d 07:08:09
Start Time 12:00 PM EST
Date October 17, 2026
Venue Merchants Bank Field at Memorial Stadium
Where To Watch FOX
Where To Stream FOX One
Season Series Season series tied 0-0.

Ohio State visits unbeaten Indiana in a Big Ten title-game rematch, but the Buckeyes are modest road favorites despite last December's defeat. A sharp passing attack meets a resilient home defense, with the spread hovering near one possession.

Home Team
Record 6-0
Last 5 5-0 last five
ATS 1-5-0 ATS
Home 4-0 home
Analysis Updated: 10:35 AM ET
Injuries Checked: 10:35 AM ET
Odds Updated: 4:49 AM ET

Betting Snapshot

Spread
IND +3.5
Open: IND 0
Market Widening

Spread Movement

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Odds Updated: 10/12 4:49 AM ET
Moneyline
IND +150
Open: IND -105
Dog Taking Support

Moneyline Movement

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Odds Updated: 10/12 4:49 AM ET
Total
50.5
Open: 48.5
Total Rising

Total Movement

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Odds Updated: 10/12 4:49 AM ET

Best Free Prop Pick

FREE PROP
Remi's Still Searching
Smith Over 85.5 receiving yards aligns with 916 yards through six games. Smith Over 85.5 receiving yards attacks an Indiana defense facing elite perimeter talent. Smith Over 85.5 receiving yards benefits from competitive game script and featured targets.

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Odds Comparison Center

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Best Home Spread
FanDuel | IND +3.5
Best Home Moneyline
DraftKings | IND +150
Best Over Line
FanDuel | 50.5
Best Away Spread
FanDuel | OHIOST -3.5
Best Away Moneyline
FanDuel | OHIOST -166
Best Under Line
BetRivers | 51.5
Updated 4:49 AM ET
Sportsbook Spread Moneyline Total
FanDuelOHIOST -3.5
IND +3.5
OHIOST -166
IND +138
O 50.5
U 50.5
DraftKingsOHIOST -3.5
IND +3.5
OHIOST -180
IND +150
O 50.5
U 50.5
BetMGMOHIOST -3.5
IND +3.5
OHIOST -175
IND +145
O 50.5
U 50.5
BetRiversOHIOST -3.5
IND +3.5
OHIOST -182
IND +145
O 51.5
U 51.5
FanaticsOHIOST -3.5
IND +3.5
OHIOST -180
IND +150
O 50.5
U 50.5
BovadaOHIOST -3.5
IND +3.5
OHIOST -175
IND +150
O 50.5
U 50.5
BetOnline.agOHIOST -3.5
IND +3.5
—O 50.5
U 50.5
LowVig.agOHIOST -3.5
IND +3.5
—O 50.5
U 50.5
MyBookie.agOHIOST -3.5
IND +3.5
OHIOST -186
IND +150
O 51.5
U 51.5
BetUSOHIOST -3.5
IND +3.5
—O 50.5
U 50.5
CaesarsOHIOST -3.5
IND +3.5
OHIOST -173
IND +147
O 50.5
U 50.5

Injury Report

Ohio State has several players listed as questionable in early-week reports, including running backs Legend Bey and Turbo Rogers, receiver Amari Valerio-Hudson and tight end Bennett Christian, with undisclosed issues reported. These are not confirmed game-day absences. One major matchup consideration is whether the Buckeyes retain their full rotational depth. Available matchup listings show no current Indiana injury entries, though official availability updates nearer kickoff remain important.

Key Players

Ohio State
Jeremiah Smith
Smith leads Ohio State with 916 receiving yards through six games.
Indiana
Josh Hoover
Hoover directs an unbeaten Indiana offense after a close road win at Nebraska.

Key Matchup Edge

Ohio State owns the cleaner betting profile at 4-2 ATS compared with Indiana's 1-5, and its vertical passing game forces defenses to account for Smith on nearly every snap. Indiana counters with home-field advantage and a defense that has allowed fewer than 12 points per game, creating genuine resistance to a road-favorite cover.

3 Things to Watch

  • Smith against Indiana coverage rotations
  • Hoover facing Ohio State pressure packages
  • Fourth-quarter scoring and field position

Betting Breakdown

Ohio State travels to Bloomington on October 17 for a noon Eastern showdown with Indiana, a rematch of the Hoosiers' 13-10 victory in the 2025 Big Ten Championship Game. The Buckeyes enter 5-1 with a 4-2 ATS mark after beating Maryland 45-16, while Indiana is 6-0 but just 1-5 against the number following a tense 20-17 escape at Nebraska. That difference matters when assessing an Ohio State line near four points: the visitors have shown better consistency relative to expectations, even if they failed to cover a large number against Maryland. Julian Sayin and Jeremiah Smith give Ohio State a potent aerial combination, with Smith reaching 916 receiving yards in six games. Indiana has not needed margin every week, relying instead on defensive resistance and timely execution. Its perfect home record raises the stakes for a Buckeyes team that split its first two road trips. The total near 49 points reflects two capable offenses meeting defenses that have usually prevented sustained scoring. Field position, turnovers and explosive plays could decide whether the favorite creates separation.

Ohio State Betting Outlook

Ohio State brings a 5-1 record to its third road contest, with its only defeat a one-point loss at Texas. The Buckeyes covered in Austin and at Iowa, where they defeated a ranked opponent 31-14, but failed to cover big home numbers against Illinois and Maryland. Sayin's downfield passing and Smith's production remain their clearest paths to beating a modest spread. Smith accumulated 916 receiving yards through six games, demanding extra defensive attention and opening secondary options. The key vulnerability is game control against quality opposition: an extended Indiana possession or stalled red-zone trip could keep this contest inside one score.

Indiana Betting Outlook

Indiana enters undefeated at 6-0 and 4-0 at home, having followed a convincing win at Rutgers with a three-point survival test at Nebraska. The Hoosiers have won every game, yet their 1-5 ATS record shows how often market expectations have run ahead of actual margins. Josh Hoover gives Indiana a stable passing presence, and its defense has surrendered fewer than 12 points per contest through six games. Still, Ohio State's perimeter speed presents a tougher assignment than most early opponents. For an Indiana ticket, the strongest case is a disciplined defensive game that limits explosives, extends drives and keeps pressure on the road favorite late.

Latest Team Buzz

Ohio State Buckeyes vs Indiana Hoosiers FAQ

What is the current spread for Ohio State Buckeyes vs Indiana Hoosiers?

The current home spread is IND +3.5, while the away spread is OHIOST -3.5.

How far has the spread moved for Ohio State Buckeyes vs Indiana Hoosiers?

The spread opened at IND 0 and is now IND +3.5.

What is the current moneyline for Ohio State Buckeyes vs Indiana Hoosiers?

The current moneyline is OHIOST -180 / IND +150.

How far has the moneyline moved for Ohio State Buckeyes vs Indiana Hoosiers?

The moneyline opened at OHIOST -115 / IND -105 and is now OHIOST -180 / IND +150.

What is the current total for Ohio State Buckeyes vs Indiana Hoosiers?

The current total is 50.5.

How far has the total moved for Ohio State Buckeyes vs Indiana Hoosiers?

The total opened at 48.5 and is now 50.5.

Is the market taking the underdog in Ohio State Buckeyes vs Indiana Hoosiers?

Current market signal: Market Widening.

Is the market taking the favorite in Ohio State Buckeyes vs Indiana Hoosiers?

Current market signal: Dog Taking Support.

Is the total dropping for Ohio State Buckeyes vs Indiana Hoosiers?

Current totals signal: Total Rising.

Is the total rising for Ohio State Buckeyes vs Indiana Hoosiers?

Current totals signal: Total Rising.

Where to watch Ohio State Buckeyes vs Indiana Hoosiers?

You can watch this game on FOX. For the latest broadcast details, see Where to Watch.

Where to stream Ohio State Buckeyes vs Indiana Hoosiers?

You can stream this game on FOX One.

What is the best free prop bet for Ohio State Buckeyes vs Indiana Hoosiers?

Remi's Still Searching

What is the biggest matchup edge for Ohio State Buckeyes vs Indiana Hoosiers?

Ohio State owns the cleaner betting profile at 4-2 ATS compared with Indiana's 1-5, and its vertical passing game forces defenses to account for Smith on nearly every snap. Indiana counters with home-field advantage and a defense that has allowed fewer than 12 points per game, creating genuine resistance to a road-favorite cover.

REMI AI PERFORMANCE

CFB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement. We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

Matchup Ohio State Buckeyes vs. Indiana Hoosiers
Game Date October 17, 2026
Venue Merchants Bank Field at Memorial Stadium
RECENT COMPLETED PICKS

AI CFB PAST PICKS

28-23 54.9% WIN
GAME
LEAN
WIN %
UNITS
RESULT
OREGST@COLOST
OREGST -6.5
56.8%
8
WIN
MICHST@WISC
WISC -8
58.2%
8
WIN
UNLV@AKRON
OVER 52.5
56.5%
6
LOSS
OREGST@UTEP
OVER 55.5
56.7%
6
LOSS
GATECH@STNFRD
OVER 47.5
56.9%
6
WIN
TEXAS@TENN
UNDER 55
57.1%
7
WIN
WAGNER@CAL
OVER 65
58.1%
8
LOSS
JMAD@SDGST
UNDER 46.5
57.1%
7
WIN
MISSST@SC
OVER 58.5
58.1%
8
WIN
FRESNO@SJST
OVER 47.5
58.1%
8
LOSS
UL@USC
OVER 59.5
56.9%
6
WIN
MEMP@BOISE
UNDER 56.5
56.9%
6
LOSS
CAL@CUSE
UNDER 57.5
56.9%
6
WIN
RICE@ND
OVER 54.5
57.0%
6
LOSS
RUT@BC
UNDER 54.5
56.9%
6
WIN
WASHST@WASH
OVER 51.5
56.9%
6
LOSS
TOWSON@NAVY
OVER 51
57.4%
7
WIN
FURMAN@TENN
OVER 67.5
57.1%
7
LOSS
MIAOH@PITT
UNDER 47.5
57.2%
7
LOSS
UTEP@OKLA
OVER 51.5
56.9%
6
LOSS
ALBANY@BUFF
ALBANY +18.5
54.1%
4
WIN
ALBANY@BUFF
UNDER 47.5
57.1%
7
WIN
UAB@ILL
KATIN HOUSER OVER 18.5 PASS COMP
54.2%
4
LOSS
HAWAII@STNFRD
HAWAII +4.5
54.8%
4
LOSS
MEMP@UNLV
UNLV -4
53.2%
3
LOSS
SJST@USC
OVER 61.5
57.0%
6
WIN
JAXST@NDAKST
UNDER 46.5
56.8%
6
WIN
NCST@UVA
CJ BAILEY OVER 29.5 PASS ATT
54.2%
4
LOSS
MIAMI@IND
ROMAN HEMBY UNDER 15.5 RUSH ATT
55.2%
5
LOSS
OLEMISS@GEORGIA
KEWAN LACY ANYTIME TD
56.7%
6
WIN
BAMA@IND
FERNANDO MENDOZA UNDER 26.5 PASS ATT
55.2%
5
WIN
OREG@TXTECH
OREG -126
58.9%
6
WIN
NEB@UTAH
DEVON DAMPIER UNDER 185.5 PASS YDS
53.4%
3
LOSS
NOTEX@SDGST
NOTEX -7
54.2%
4
LOSS
BAMA@OKLA
ISAIAH SATEGNA III ANYTIME TD
54.2%
4
WIN
BYU@TTU
PARKER KINGSTON OVER 20.5 LONGEST RECEPTION
54.3%
4
WIN
UNLV@BOISE
BOISE -4.5
56.7%
6
WIN
ECU@FAU
FAU +7
57.8%
7
LOSS
OREG@WASH
WASH +7
54.9%
4
LOSS
WYO@HAWAII
WYO +7.5
55.1%
5
LOSS
COLO@KSTATE
COLO +17.5
54.0%
4
WIN
OHIOST@MICH
MICH +10.5
56.4%
6
LOSS
VATECH@UVA
VATECH +8
57.8%
7
LOSS
NWEST@ILL
LUKE ALTMYER UNDER 19.5 PASS COMP
54.3%
4
WIN
ORE@WAS
DEMOND WILLIAMS JR UNDER 43.5 RUSH YDS
55.2%
5
WIN
MIAMI@VATECH
VATECH +18.5
54.2%
4
WIN
GAST@TROY
TROY -9.5
55.7%
5
WIN
DEL@WAKE
DEL +18
56.7%
6
LOSS
NMEX@AF
NMEX -3.5
56.1%
5
WIN
WASHST@JMAD
WASHST +14.5
55.3%
5
WIN
ILL@WISC
WISC +9
55.1%
5
WIN
Past performance is not a guarantee of future results. Picks are displayed for informational purposes only.