Away Team
Record 1-0
Last 5 4-1 last five
ATS 0-1-0 ATS
Road 0-0 road
Standings
CFB Game Preview
Schedule
Kickoff Countdown
6d 01:31:15
Start Time 12:00 PM EST
Date September 12, 2026
Venue Ross-Ade Stadium
Where To Watch FS1
Where To Stream FOX One
Season Series Season series tied 0-0.

Wake Forest arrives as a 5.5-point road favorite after Gio Lopez lit up Akron, but Purdue countered with 523 yards in its opener. Carlos Hernandez's chest status and both teams' Week 1 penalty issues make this a volatile early-season number.

Home Team
Record 1-0
Last 5 1-4 last five
ATS 0-1-0 ATS
Home 1-0 home
Analysis Updated: 7:42 AM ET
Injuries Checked: 7:40 AM ET
Odds Updated: 10:19 AM ET

Betting Snapshot

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Best Free Prop Pick

FREE PROP
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Gio Lopez Over 249.5 passing yards: he opened with 350 yards on 32 attempts. Gio Lopez Over 249.5 passing yards: Purdue allowed 241.7 passing yards per game last season. Gio Lopez Over 249.5 passing yards: a competitive road script should sustain full-game passing volume.

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Best Home Spread
FanDuel | PURDUE +4.5
Best Home Moneyline
FanDuel | PURDUE +152
Best Over Line
FanDuel | 50.5
Best Away Spread
FanDuel | WAKE -4.5
Best Away Moneyline
FanDuel | WAKE -184
Best Under Line
FanDuel | 50.5
Updated 10:19 AM ET
Sportsbook Spread Moneyline Total
FanDuelWAKE -4.5
PURDUE +4.5
WAKE -184
PURDUE +152
O 50.5
U 50.5

Injury Report

Wake Forest wideout Carlos Hernandez is questionable with a chest injury after producing five catches for 165 yards and a touchdown before exiting against Akron. Receiver Nick Carr is also questionable with an undisclosed issue. Purdue tight end Kylan Fox remains out with a knee injury, reducing depth at a position already carrying added responsibility in the passing game.

Key Players

Wake Forest
Gio Lopez
Threw for 350 yards and three touchdowns, adding 39 rushing yards in opener.
Purdue
Ryan Browne
Completed 23 of 29 for 317 yards, three touchdowns and no interceptions.

Key Matchup Edge

Wake Forest owns the cleaner explosive-pass profile: Lopez produced 350 yards with three scores and no picks, while Purdue allowed 241.7 passing yards per game in 2025. If Hernandez is available, the Deacons have enough downfield stress to justify road-favorite status despite Ross-Ade home field.

3 Things to Watch

  • Carlos Hernandez chest status
  • Wake Forest explosive pass game
  • Purdue red-zone finishing under pressure

Betting Breakdown

Wake Forest and Purdue both opened 1-0 with comfortable wins, yet neither covered a large Week 1 spread. The Deacons beat Akron 38-16 while piling up 559 yards, including 356 through the air behind Gio Lopez, but 11 penalties for 115 yards and the Carlos Hernandez chest issue leave legitimate cleanup points. Purdue answered with 523 yards in a 44-19 win over Indiana State, led by Ryan Browne's 317 passing yards and three touchdowns, though nine penalties and early red-zone stalls kept the game less efficient than the final margin suggests. The market has Wake Forest favored by 5.5 with a 50.5 total, reflecting the Deacons' stronger 2025 foundation and immediate offensive ceiling. Purdue's home field and upgraded passing game keep the dog live, but Wake's balance, defensive baseline and explosive quarterback play create the more trustworthy side if the receiving corps is close to full strength.

Wake Forest Betting Outlook

Wake Forest brings a 1-0 record and a 4-1 mark across its five most recent games after closing 2025 with a 9-4 season and bowl victory. Lopez immediately upgraded the passing ceiling with 350 yards and three touchdowns against Akron, while the offense also produced 203 rushing yards. The concern is discipline after 11 penalties for 115 yards, plus Hernandez's questionable chest status after his 165-yard first half. As a 5.5-point road favorite, Wake needs cleaner execution and continued explosive passing to separate from a Purdue team that showed real offensive improvement in its opener.

Purdue Betting Outlook

Purdue snapped a 10-game losing streak by beating Indiana State 44-19 and generated 523 total yards in the process. Browne was sharp at 23-of-29 for 317 yards and three touchdowns, Asaad Waseem debuted with six catches for 107 yards, and Fame Ijeboi added 87 rushing yards with a score. The Boilermakers still committed nine penalties for 85 yards and settled for field goals early, issues that matter more against Wake Forest. Getting 5.5 points at Ross-Ade is attractive if Browne maintains efficiency, but Purdue must protect possessions and finish drives better than it did in the first half of Week 1.

Latest Team Buzz

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What is the biggest matchup edge for Wake Forest Demon Deacons vs Purdue Boilermakers?

Wake Forest owns the cleaner explosive-pass profile: Lopez produced 350 yards with three scores and no picks, while Purdue allowed 241.7 passing yards per game in 2025. If Hernandez is available, the Deacons have enough downfield stress to justify road-favorite status despite Ross-Ade home field.

REMI AI PERFORMANCE

CFB Past Picks

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Matchup Wake Forest Demon Deacons vs. Purdue Boilermakers
Game Date September 12, 2026
Venue Ross-Ade Stadium
RECENT COMPLETED PICKS

AI CFB PAST PICKS

30-21 58.8% WIN
GAME
LEAN
WIN %
UNITS
RESULT
ALBANY@BUFF
ALBANY +18.5
54.1%
4
WIN
ALBANY@BUFF
UNDER 47.5
57.1%
7
WIN
UAB@ILL
KATIN HOUSER OVER 18.5 PASS COMP
54.2%
4
LOSS
HAWAII@STNFRD
HAWAII +4.5
54.8%
4
LOSS
MEMP@UNLV
UNLV -4
53.2%
3
LOSS
SJST@USC
OVER 61.5
57.0%
6
WIN
JAXST@NDAKST
UNDER 46.5
56.8%
6
WIN
NCST@UVA
CJ BAILEY OVER 29.5 PASS ATT
54.2%
4
LOSS
MIAMI@IND
ROMAN HEMBY UNDER 15.5 RUSH ATT
55.2%
5
LOSS
OLEMISS@GEORGIA
KEWAN LACY ANYTIME TD
56.7%
6
WIN
BAMA@IND
FERNANDO MENDOZA UNDER 26.5 PASS ATT
55.2%
5
WIN
OREG@TXTECH
OREG -126
58.9%
6
WIN
NEB@UTAH
DEVON DAMPIER UNDER 185.5 PASS YDS
53.4%
3
LOSS
NOTEX@SDGST
NOTEX -7
54.2%
4
LOSS
BAMA@OKLA
ISAIAH SATEGNA III ANYTIME TD
54.2%
4
WIN
BYU@TTU
PARKER KINGSTON OVER 20.5 LONGEST RECEPTION
54.3%
4
WIN
UNLV@BOISE
BOISE -4.5
56.7%
6
WIN
ECU@FAU
FAU +7
57.8%
7
LOSS
OREG@WASH
WASH +7
54.9%
4
LOSS
WYO@HAWAII
WYO +7.5
55.1%
5
LOSS
COLO@KSTATE
COLO +17.5
54.0%
4
WIN
OHIOST@MICH
MICH +10.5
56.4%
6
LOSS
VATECH@UVA
VATECH +8
57.8%
7
LOSS
NWEST@ILL
LUKE ALTMYER UNDER 19.5 PASS COMP
54.3%
4
WIN
ORE@WAS
DEMOND WILLIAMS JR UNDER 43.5 RUSH YDS
55.2%
5
WIN
MIAMI@VATECH
VATECH +18.5
54.2%
4
WIN
GAST@TROY
TROY -9.5
55.7%
5
WIN
DEL@WAKE
DEL +18
56.7%
6
LOSS
NMEX@AF
NMEX -3.5
56.1%
5
WIN
WASHST@JMAD
WASHST +14.5
55.3%
5
WIN
ILL@WISC
WISC +9
55.1%
5
WIN
WKY@LSU
WKY +23.5
56.3%
6
WIN
WASH@UCLA
DEMOND WILLIAMS UNDER 27.5 PASS ATT
56.3%
6
WIN
TCU@HOU
AMARE THOMAS OVER 69.5 RECV YDS
55.2%
5
WIN
TEX@UGA
NATE FRAZIER UNDER 65.5 RUSH + REC YDS
55.5%
5
WIN
PUR@WASH
ANTONIO HARRIS UNDER 73.5 RUSH + REC YDS
54.1%
4
WIN
UVA@DUKE
DUKE -3.5
54.7%
3
LOSS
OKLA@BAMA
BAMA -6
54.5%
3
LOSS
OREGST@TULSA
OREGST -120
55.6%
5
LOSS
UTEP@MIZZST
MIZZST -5
54.3%
4
WIN
COLOST@NMEX
NMEX -14
57.1%
6
LOSS
PSU@MICHST
MICHST +7.5
56.5%
6
LOSS
MISSST@MIZZOU
MISSST +7.5
57.2%
7
LOSS
FAU@TULANE
FAU +17.5
56.0%
6
WIN
NCST@MIAMI
NCST +15.5
57.1%
7
LOSS
KENTST@AKRON
AKRON -6.5
55.4%
5
LOSS
JAXST@UTEP
JAXST -105
57.0%
7
WIN
FSU@CLEM
CLEM -118
57.1%
5
WIN
UNLV@COLOST
UNLV -4
55.2%
5
WIN
OREG@IOWA
IOWA +6.5
53.3%
2
WIN
NEB@UCLA
NEB +1.5
55.8%
5
WIN
Past performance is not a guarantee of future results. Picks are displayed for informational purposes only.