Boilermakers vs. Spartans
Prediction, Odds & Props
Nov 22 | CFB AI Picks
Updated: 2024-11-15T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
On November 22, 2024, the Purdue Boilermakers will face the Michigan State Spartans at Spartan Stadium in East Lansing, Michigan. Both teams are looking to close their seasons on a positive note, with Purdue trying to snap a long losing streak and Michigan State aiming to solidify their bowl eligibility hopes.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Nov 22, 2024
Start Time: 9:00 PM EST​
Venue: Spartan Stadium​
Spartans Record: (4-6)
Boilermakers Record: (1-9)
OPENING ODDS
PURDUE Moneyline: +400
MICHST Moneyline: -549
PURDUE Spread: +14.5
MICHST Spread: -14.5
Over/Under: 48.5
PURDUE
Betting Trends
- Purdue has struggled against the spread (ATS) this season, with a disappointing 2-7-0 record, covering only 22.2% of their games.
MICHST
Betting Trends
- Michigan State has fared slightly better ATS, holding a 3-5-1 record, covering 37.5% of their games.
MATCHUP TRENDS
- Michigan State has dominated this matchup at home, winning the last five meetings against Purdue at Spartan Stadium, highlighting their historical edge in East Lansing.
PURDUE vs. MICHST
Best Prop Bet
- Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.
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Purdue vs Michigan State Prediction & Odds:
Free CFB Betting Insights for 11/22/24
Michigan State’s balanced approach, with an average of 245 passing yards and 140 rushing yards per game, has kept opposing defenses guessing. The Spartans’ ability to sustain drives and control the clock has been a critical factor in their four wins this season. Defensively, Purdue has struggled to stop opponents, allowing 31.2 points per game. Their run defense has been a major weakness, conceding 210.5 rushing yards per game, while the secondary has given up 220.8 passing yards per game. Linebacker Kydran Jenkins has been a standout, leading the team with 75 tackles and 4 sacks, but the defense has lacked depth and consistency. Conversely, Michigan State’s defense has been more effective, allowing 26.5 points per game. The Spartans’ run defense has been solid, holding opponents to 130.7 rushing yards per game, but their pass defense has shown vulnerabilities, surrendering 245.3 passing yards per game. Defensive end Simeon Barrow and linebacker Cal Haladay have anchored the unit, with Barrow contributing 6 sacks and Haladay leading the team with 82 tackles. With Michigan State playing at home and boasting a more balanced offense and a slightly better defense, they are the clear favorites. Purdue’s best chance lies in limiting turnovers and finding ways to exploit Michigan State’s secondary, but their struggles on both sides of the ball make an upset unlikely.
Game week.#BoilerUp | @purdueglobal pic.twitter.com/B5R8OecKZY
— Purdue Football (@BoilerFootball) November 18, 2024
Purdue Boilermakers CFB Preview
The Michigan State Spartans enter their matchup against Purdue with a 4-5 record under head coach Mel Tucker. The Spartans have shown flashes of potential on both sides of the ball this season, and a win against Purdue would bring them closer to bowl eligibility. Offensively, Michigan State has been effective, averaging 24.8 points per game. Quarterback Katin Houser has been a steady presence, throwing for 2,145 yards with 18 touchdowns and 8 interceptions. Houser’s ability to distribute the ball has been key to the Spartans’ success, with wide receivers Montorie Foster Jr. and Tre Mosley combining for over 1,200 receiving yards and 10 touchdowns. The running game has also been productive, led by Jalen Berger, who has rushed for 678 yards and 6 touchdowns. Michigan State’s offensive line has provided solid protection for Houser, allowing the offense to maintain a balance between the pass and the run. This balance has been critical in sustaining drives and keeping opposing defenses on their heels. Defensively, the Spartans have been solid, allowing 26.5 points per game. The run defense has been a strength, conceding just 130.7 yards per game, thanks to the efforts of defensive linemen Simeon Barrow and linebackers Cal Haladay and Jacoby Windmon. Barrow leads the team with 6 sacks, consistently pressuring opposing quarterbacks, while Haladay has been the team’s top tackler with 82 stops on the season. However, the pass defense has shown vulnerabilities, giving up 245.3 passing yards per game. Despite this, Michigan State’s ability to generate pressure and disrupt offensive rhythm has kept their defense competitive. To secure a win against Purdue, Michigan State will need to exploit the Boilermakers’ defensive weaknesses, particularly their inability to stop the run. Establishing the ground game early with Berger will open up opportunities for Houser to take advantage of Purdue’s vulnerable secondary. Defensively, the Spartans must focus on containing Purdue quarterback Brady Allen and limiting big plays in the passing game. Given their balanced offense, home-field advantage, and more reliable defense, Michigan State is well-positioned to come out on top in this matchup.

Credit: USA TODAY/IMAGN
Michigan State Spartans CFB Preview
The Purdue Boilermakers have endured a difficult 2024 season, entering the matchup against Michigan State with a 1-8 record under head coach Ryan Walters. The team has faced challenges across the board, particularly on offense, where they have struggled to consistently produce points and sustain drives. Offensively, Purdue has averaged just 17.5 points per game, one of the lowest marks in the Big Ten. Quarterback Brady Allen has shown moments of potential but has struggled with turnovers, throwing for 1,892 yards with 12 touchdowns and 10 interceptions. Allen’s inconsistency has hindered the team’s ability to capitalize on scoring opportunities. The rushing attack has been equally disappointing, averaging only 95.7 yards per game. Running back Devin Mockobee leads the team with 432 rushing yards but has faced difficulties finding running lanes due to inconsistent blocking from the offensive line. Purdue’s receiving corps has been a rare bright spot, with TJ Sheffield and Deion Burks combining for over 1,200 receiving yards and 8 touchdowns. However, the lack of balance between the passing and rushing attacks has made the Boilermakers’ offense predictable and easier for opposing defenses to stop. Defensively, Purdue has struggled to contain opponents, allowing 31.2 points per game. The run defense has been a significant weakness, giving up 210.5 rushing yards per game, ranking among the worst in the Big Ten. The pass defense has been marginally better, allowing 220.8 passing yards per game, but the lack of a consistent pass rush has left the secondary exposed. Linebacker Kydran Jenkins has been a bright spot, leading the team with 75 tackles and 4 sacks, but the defense as a whole has lacked playmakers capable of changing the game. Missed tackles, poor coverage, and an inability to generate turnovers have compounded Purdue’s defensive struggles. For Purdue to compete against Michigan State, they will need a near-flawless performance from their offense, particularly quarterback Brady Allen, who must limit turnovers and capitalize on scoring opportunities. Defensively, the Boilermakers will need to find a way to slow down Michigan State’s balanced attack, especially running back Jalen Berger, who has been effective on the ground. While an upset is not impossible, Purdue’s struggles on both sides of the ball make their path to victory narrow.
Game Week in EL pic.twitter.com/mbPSs4sxnF
— Michigan State Football (@MSU_Football) November 19, 2024
Purdue vs. Michigan State Prop Picks (AI)
Purdue vs. Michigan State Prediction (AI)

Remi, our AI sports genius, has been pouring over mountains of data from every angle between the Boilermakers and Spartans and using recursive machine learning and impressive AI to examine the data to a single cover probability.
Oddly enough, we’ve seen the AI has been most keyed in on the linear correlation of factor human bettors regularly put on Purdue’s strength factors between a Boilermakers team going up against a possibly tired Spartans team. It appears the true game analytics might reflect a strong lean against one Vegas line specifically.
Unlock this in-depth AI prediction and all of our CFB AI picks for FREE now.
Below is our current AI Purdue vs Michigan State picks, computer picks Boilermakers vs Spartans, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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CFB | 9/26 | TCU@ARIZST | UNLOCK THIS PICK | 3 |
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CFB | 9/26 | FSU@UVA | UNLOCK THIS PICK | 0 |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CFB schedule.Â
Boilermakers Betting Trends
Purdue has struggled against the spread (ATS) this season, with a disappointing 2-7-0 record, covering only 22.2% of their games.
Spartans Betting Trends
Michigan State has fared slightly better ATS, holding a 3-5-1 record, covering 37.5% of their games.
Boilermakers vs. Spartans Matchup Trends
Michigan State has dominated this matchup at home, winning the last five meetings against Purdue at Spartan Stadium, highlighting their historical edge in East Lansing.
Purdue vs. Michigan State Game Info
What time does Purdue vs Michigan State start on November 22, 2024?
Purdue vs Michigan State starts on November 22, 2024 at 9:00 PM EST.
Where is Purdue vs Michigan State being played?
Venue: Spartan Stadium.
What are the opening odds for Purdue vs Michigan State?
Spread: Michigan State -14.5
Moneyline: Purdue +400, Michigan State -549
Over/Under: 48.5
What are the records for Purdue vs Michigan State?
Purdue: (1-9) Â |Â Michigan State: (4-6)
What is the AI best bet for Purdue vs Michigan State?
Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.. Prices move—always shop for the best number.
What are Purdue vs Michigan State trending bets?
Michigan State has dominated this matchup at home, winning the last five meetings against Purdue at Spartan Stadium, highlighting their historical edge in East Lansing.
What are Purdue trending bets?
PURDUE trend: Purdue has struggled against the spread (ATS) this season, with a disappointing 2-7-0 record, covering only 22.2% of their games.
What are Michigan State trending bets?
MICHST trend: Michigan State has fared slightly better ATS, holding a 3-5-1 record, covering 37.5% of their games.
Where can I find AI Picks for Purdue vs Michigan State?
See our latest CFB picks and odds pages for 2024 to compare prices before you bet.
Purdue vs. Michigan State Odds
AI algorithm Remi is pouring through loads of data points on each player. In fact, anytime the Purdue vs Michigan State trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme hostile environments seemingly never follow normal, predictable patterns.
Purdue vs Michigan State Opening Odds
PURDUE Moneyline:
+400 MICHST Moneyline: -549
PURDUE Spread: +14.5
MICHST Spread: -14.5
Over/Under: 48.5
Purdue vs Michigan State Live Odds
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+240
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Western Kentucky Hilltoppers
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-175
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U 60 (-115)
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O 55.5 (-115)
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Oregon Ducks
Penn State Nittany Lions
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OREG
PSU
|
–
–
|
+150
-175
|
+3.5 (-110)
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|
O 53 (-105)
U 53 (-115)
|
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Sep 27, 2025 7:30PM EDT
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Boise State Broncos
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APPST
BOISE
|
–
–
|
-850
|
-16.5 (-110)
|
O 59.5 (-105)
U 59.5 (-115)
|
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Alabama Crimson Tide
Georgia Bulldogs
9/27/25 7:30PM
BAMA
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|
–
–
|
+115
-135
|
+2 (-110)
-2 (-110)
|
O 53.5 (-115)
U 53.5 (-105)
|
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Sep 27, 2025 7:30PM EDT
Umass Minutemen
Missouri Tigers
9/27/25 7:30PM
UMASS
MIZZOU
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–
–
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-44.5 (-105)
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O 57 (-110)
U 57 (-110)
|
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Sep 27, 2025 7:30PM EDT
San Jose State Spartans
Stanford Cardinal
9/27/25 7:30PM
SJST
STNFRD
|
–
–
|
+130
-150
|
+3 (-110)
-3 (-110)
|
O 50 (-105)
U 50 (-115)
|
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Sep 27, 2025 7:30PM EDT
Washington State Cougars
Colorado State Rams
9/27/25 7:30PM
WASHST
COLOST
|
–
–
|
+180
-220
|
+6 (-115)
-6 (-105)
|
O 49 (-105)
U 49 (-115)
|
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Sep 27, 2025 7:45PM EDT
Kentucky Wildcats
South Carolina Gamecocks
9/27/25 7:45PM
UK
SC
|
–
–
|
+180
-220
|
+6 (-115)
-6 (-105)
|
O 47 (-115)
U 47 (-105)
|
|
Sep 27, 2025 8:00PM EDT
Marshall Thundering Herd
Louisiana Ragin Cajuns
9/27/25 8PM
MARSH
UL
|
–
–
|
-130
+110
|
-2 (-110)
+2 (-110)
|
O 48 (-110)
U 48 (-110)
|
|
Sep 27, 2025 9:00PM EDT
Louisiana Tech Bulldogs
UTEP Miners
9/27/25 9PM
LATECH
UTEP
|
–
–
|
-170
+145
|
-3.5 (+100)
+3.5 (-120)
|
O 48 (-110)
U 48 (-110)
|
|
Sep 27, 2025 10:15PM EDT
BYU Cougars
Colorado Buffaloes
9/27/25 10:15PM
BYU
COLO
|
–
–
|
-230
+190
|
-6 (-115)
+6 (-105)
|
O 49.5 (-120)
U 49.5 (+100)
|
|
Oct 4, 2025 12:00PM EDT
Minnesota Golden Gophers
Ohio State Buckeyes
10/4/25 12PM
MINN
OHIOST
|
–
–
|
|
+21 (-110)
-21 (-110)
|
|
|
Oct 4, 2025 12:00PM EDT
Kentucky Wildcats
Georgia Bulldogs
10/4/25 12PM
UK
UGA
|
–
–
|
|
+20.5 (-110)
-20.5 (-110)
|
|
|
Oct 4, 2025 12:00PM EDT
Clemson Tigers
North Carolina Tar Heels
10/4/25 12PM
CLEM
UNC
|
–
–
|
-550
+400
|
-13.5 (-110)
+13.5 (-110)
|
O 48.5 (-110)
U 48.5 (-110)
|
|
Oct 4, 2025 12:00PM EDT
Wisconsin Badgers
Michigan Wolverines
10/4/25 12PM
WISC
MICH
|
–
–
|
+580
-880
|
+16.5 (-110)
-16.5 (-110)
|
O 41.5 (-105)
U 41.5 (-115)
|
|
Oct 4, 2025 1:00PM EDT
UTSA Roadrunners
Temple Owls
10/4/25 1PM
UTSA
TEMPLE
|
–
–
|
-210
+172
|
-5.5 (-115)
+5.5 (-105)
|
O 56.5 (-110)
U 56.5 (-110)
|
|
Oct 4, 2025 3:30PM EDT
Vanderbilt Commodores
Alabama Crimson Tide
10/4/25 3:30PM
VANDY
BAMA
|
–
–
|
+360
-480
|
+11.5 (-102)
-11.5 (-120)
|
O 51.5 (-110)
U 51.5 (-110)
|
|
Oct 4, 2025 3:30PM EDT
Washington Huskies
Maryland Terrapins
10/4/25 3:30PM
WASH
MD
|
–
–
|
|
-7 (-110)
+7 (-110)
|
|
|
Oct 4, 2025 3:30PM EDT
Boise State Broncos
Notre Dame Fighting Irish
10/4/25 3:30PM
BOISE
ND
|
–
–
|
+365
-490
|
+15.5 (-110)
-15.5 (-110)
|
O 61.5 (-110)
U 61.5 (-110)
|
|
Oct 4, 2025 3:30PM EDT
Texas Longhorns
Florida Gators
10/4/25 3:30PM
TEXAS
FLA
|
–
–
|
-300
+240
|
-7.5 (-110)
+7.5 (-110)
|
O 46.5 (-110)
U 46.5 (-110)
|
|
Oct 4, 2025 4:00PM EDT
Kent State Golden Flashes
Oklahoma Sooners
10/4/25 4PM
KENT
OKLA
|
–
–
|
|
+45.5 (-110)
-45.5 (-110)
|
O 52.5 (-115)
U 52.5 (-105)
|
|
Oct 4, 2025 4:00PM EDT
Michigan State Spartans
Nebraska Cornhuskers
10/4/25 4PM
MICHST
NEB
|
–
–
|
+360
-480
|
+12.5 (-105)
-12.5 (-115)
|
O 53.5 (-110)
U 53.5 (-110)
|
CFB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Purdue Boilermakers vs. Michigan State Spartans on November 22, 2024 at Spartan Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.
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   LEAN |    %WIN |    UNITS | RESULT |
---|---|---|---|---|
TULANE@OLEMISS | MISS -11.5 | 54.3% | 4 | WIN |
UNC@UCF | UCF -6.5 | 54.4% | 4 | WIN |
ARKST@KENSAW | KENSAW +4.5 | 54.5% | 4 | WIN |
ILL@IND | IND -6 | 53.2% | 3 | WIN |
SELOU@LSU | LSU -47.5 | 55.3% | 5 | LOSS |
TNMART@MIZZST | MIZZST -14.5 | 56.2% | 6 | WIN |
FRESNO@HAWAII | HAWAII +3 | 56.6% | 6 | WIN |
MRSHL@MTSU | MTSU +2.5 | 56.8% | 6 | LOSS |
MICH@NEB | NEB +1.5 | 57.3% | 7 | LOSS |
WASH@WASHST | DENZEL BOSTON UNDER 69.5 RECV YDS | 56.2% | 6 | LOSS |
IOWA@RUT | ANTWAN RAYMOND OVER 0.5 TOUCHDOWNS | 54.4% | 4 | WIN |
GEORGIA@TENN | UNDER 50.5 | 55.5% | 6 | LOSS |
ARK@OLEMISS | MISS -225 | 72.0% | 9 | WIN |
DUKE@TULANE | TULANE -120 | 56.5% | 4 | WIN |
ARK@OLEMISS | MISS -6.5 | 53.9% | 3 | LOSS |
AKRON@UAB | UAB -11 | 54.7% | 4 | LOSS |
UCONN@DEL | DEL +9.5 | 55.0% | 5 | WIN |
APLST@USM | USM +4 | 55.3% | 6 | WIN |
MERIMK@KENSAW | KENSAW -13.5 | 56.2% | 7 | WIN |
UMASS@IOWA | IOWA -34.5 | 56.4% | 7 | WIN |
UMASS@IOWA | JAZIUN PATTERSON UNDER 0.5 RUSH TDS | 54.8% | 4 | WIN |
NMEX@UCLA | NICO IAMALEAVA UNDER 31.5 PASS ATT | 53.4% | 3 | LOSS |
KSTATE@ARIZ | ARIZ +1.5 | 56.1% | 6 | WIN |
BC@MICHST | NICK MARSH OVER 47.5 RCV YDS | 53.6% | 3 | WIN |
ARIZST@MISSST | MISSST +7 | 54.2% | 4 | WIN |
TULSA@NMEXST | NMEXST +3.5 | 56.9% | 6 | WIN |
UCLA@UNLV | OVER 54.5 | 56.2% | 6 | LOSS |
FRESNO@OREGST | FRESNO +1.5 | 54.7% | 4 | WIN |
VANDY@VATECH | VANDY +2.5 | 55.8% | 5 | WIN |
JMAD@LVILLE | LVILLE -14.5 | 54.0% | 3 | LOSS |
TCU@UNC | JOSEPH MANJACK OVER 37.5 RECV YDS | 53.8% | 3 | LOSS |
ND@MIAMI | MIAMI +3 | 55.2% | 6 | WIN |
MISSST@USM | USM +14.5 | 56.0% | 6 | LOSS |
UTAH@UCLA | UCLA +5.5 | 56.2% | 6 | LOSS |
CAL@OREGST | OREGST +1.5 | 55.1% | 5 | LOSS |
FAU@MD | MD -13.5 | 55.2% | 5 | WIN |
GAS@FRESNO | FRESNO +2 | 55.2% | 5 | WIN |
TOLEDO@UK | UK -9.5 | 56.2% | 6 | LOSS |
AUSTPEAY@MTSU | PEAY +12.5 | 56.2% | 6 | WIN |
LSU@CLEM | GARRETT NUSSMEIER OVER 23.5 PASS COMP | 54.1% | 3 | WIN |
WMICH@MICHST | WMICH +21.5 | 56.2% | 6 | WIN |
ND@OHIOST | WILL HOWARD INTERCEPTIONS OVER 0.5 | 54.80% | 4 | LOSS |
OHIOST@TEXAS | WILL HOWARD PASS + RUSH YDS UNDER 262.5 | 54.70% | 4 | LOSS |
GEORGIA@TEXAS | TEXAS -144 | 54.40% | 4 | LOSS |
AUBURN@BAMA | PAYTON THORNE PASS TDS - UNDER 1.5 | 53.20% | 3 | WIN |
PURDUE@IND | IND -28.5 | 53.90% | 3 | WIN |
FRESNO@UCLA | T.J. HARDEN LONGEST RUSH OVER 17.5 YDS | 54.50% | 4 | LOSS |
TENN@VANDY | VANDY +10.5 | 54.90% | 4 | LOSS |
WVU@TXTECH | TXTECH -2.5 | 54.60% | 4 | WIN |
SC@CLEM | CLEM -130 | 58.70% | 4 | LOSS |
TCU@CINCY | TCU -3 | 54.20% | 4 | WIN |