Away Team
Record 1-0
Last 5 1-0 in one completed game
ATS 0-0-0 ATS
Road 0-0 road
Standings
CBB Game Preview
Schedule
Tipoff Countdown
11:06:14
Start Time 8:00 PM EST
Date November 06, 2026
Venue Hilton Coliseum
Where To Watch ESPN+
Where To Stream ESPN+
Season Series Iowa State won the last meeting 73-45 in 2019

Iowa State failed to cover as a 14.5-point favorite in an 80-76 opening loss to Memphis, while Southern Miss rolled Tougaloo 82-35, setting up a home opener where the Cyclones need a sharper perimeter showing.

Home Team
Record 0-1
Last 5 0-1 in one completed game
ATS 0-1-0 ATS
Home 0-0 home
Analysis Updated: 3:51 AM ET
Injuries Checked: 3:50 AM ET
Odds Updated: 8:49 AM ET

Betting Snapshot

Spread
IOWAST -31.5
Open: IOWAST -30.5
Market Widening

Spread Movement

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Odds Updated: 11/6 8:49 AM ET
Moneyline
IOWAST -100000
Open: IOWAST -100000
Market Steady

Moneyline Movement

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Odds Updated: 11/6 8:49 AM ET
Total
149.5
Open: 148.5
Total Rising

Total Movement

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Odds Updated: 11/6 8:49 AM ET

Best Free Prop Pick

FREE PROP
Remi's Still Searching
Ryan Prather Jr. scored 19 points on 6-of-11 shooting with three threes versus Memphis. Tre Singleton posted 11 points and 11 rebounds in Iowa State's season opener. Isaac Taveras led Southern Miss with 12 points and 9 rebounds against Tougaloo.

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Odds Comparison Center

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Best Home Spread
FanDuel | IOWAST -30.5
Best Home Moneyline
BetMGM | IOWAST -10000
Best Over Line
DraftKings | 149.5
Best Away Spread
DraftKings | USM +31.5
Best Away Moneyline
Fanatics | USM +9000
Best Under Line
FanDuel | 150.5
Updated 8:49 AM ET
Sportsbook Spread Moneyline Total
FanDuelUSM +30.5
IOWAST -30.5
—O 150.5
U 150.5
DraftKingsUSM +31.5
IOWAST -31.5
USM +5000
IOWAST -100000
O 149.5
U 149.5
BetMGMUSM +31.5
IOWAST -31.5
USM +3300
IOWAST -10000
O 150.5
U 150.5
BetRiversUSM +30.5
IOWAST -30.5
—O 150.5
U 150.5
FanaticsUSM +31
IOWAST -31
USM +9000
IOWAST -50000
O 150
U 150
BovadaUSM +30.5
IOWAST -30.5
USM +4500
IOWAST -100000
O 150.5
U 150.5
BetOnline.agUSM +31
IOWAST -31
—O 149.5
U 149.5
LowVig.agUSM +31
IOWAST -31
—O 149.5
U 149.5
BetUSUSM +31
IOWAST -31
—O 149.5
U 149.5
CaesarsUSM +30.5
IOWAST -30.5
—O 150.5
U 150.5

Injury Report

Iowa State remains without guard Killyan Toure, a key rotation contributor, and Taj Manning was limited to 15 minutes against Memphis with a calf issue noted. Dominykas Pleta was held to three first-half minutes by early fouls yet still scored 15 points in 11 minutes. No significant injuries are listed for Southern Miss, which played all 15 rostered players in its opener, giving the Golden Eagles full depth for a pressing approach.

Key Players

USM
Isaac Taveras
Taveras led Southern Miss with 12 points and 9 rebounds against Tougaloo.
Iowa State
Ryan Prather Jr.
Prather scored 19 points off the bench on 6-of-11 shooting against Memphis.

Key Matchup Edge

Southern Miss forced 22 turnovers with 15 steals in its opener, but Iowa State committed only 11 turnovers against Memphis and holds a major talent edge inside, where Pleta and Tre Singleton combined for 26 points and Singleton grabbed 11 rebounds.

3 Things to Watch

  • Iowa State three-point shooting after 4-of-20 opener
  • Southern Miss ball pressure against Cyclones guards
  • Dominykas Pleta staying out of foul trouble

Betting Breakdown

No. 18 Iowa State returns to Ames for its home opener after an 80-76 loss to Memphis at the Sanford Pentagon, a game the Cyclones trailed 40-39 at halftime and never fully controlled. The defeat came as roughly a 14.5-point favorite, leaving Iowa State 0-1 straight up and against the spread. The biggest culprit was perimeter shooting, as the Cyclones made only 4-of-20 threes and 68.8 percent of their free throws while Memphis converted 25-of-33 at the line and won fast-break points 14-5. Ryan Prather Jr. provided 19 points off the bench, Dominykas Pleta added 15 in only 11 minutes and Tre Singleton posted 11 points and 11 rebounds. Southern Miss enters 1-0 after beating Tougaloo 82-35, using 13 scorers, 45 bench points, 15 steals and 22 forced turnovers. That came after exhibition losses to New Orleans by 10 and Houston Christian by 29, so Friday is a major step up in class. Expect Iowa State to lean on its size and defense while trying to steady its shooting from deep.

USM Betting Outlook

Southern Miss opened 1-0 with an 82-35 win over Tougaloo in which all 15 rostered players appeared and 13 scored. Isaac Taveras led the way with 12 points and 9 rebounds, Cameron Wallace added 11 points and 8 rebounds on 5-of-9 shooting, and Brandon Weston chipped in 9 points with two threes. Jalyke Gaines-Wyatt ran the offense with 5 assists and a plus-39 rating. The Golden Eagles were dominant defensively, generating 15 steals and 22 turnovers, but they lost exhibitions to New Orleans and Houston Christian by double digits, a warning sign against a ranked Big 12 opponent on the road in their first true test of the season.

Iowa State Betting Outlook

Iowa State dropped its opener 80-76 to Memphis in Sioux Falls despite outshooting the Tigers 43.1 percent to 41.8 percent from the field. The Cyclones were undone by 4-of-20 three-point shooting, including 1-of-7 from Tamin Lipsey and 0-of-4 from Jamarion Batemon, plus a 25-of-33 Memphis showing at the free-throw line. Robert Morris transfer Ryan Prather Jr. was the bright spot with 19 points and three made threes, Dominykas Pleta scored 15 in 11 minutes, and Tre Singleton recorded an 11-point, 11-rebound double-double. Iowa State still owns the size advantage on the glass and should be a heavy favorite at home in its first game at Hilton Coliseum this season.

Latest Team Buzz

USM Golden Eagles vs Iowa State Cyclones FAQ

What is the current spread for USM Golden Eagles vs Iowa State Cyclones?

The current home spread is IOWAST -31.5, while the away spread is USM +31.5.

How far has the spread moved for USM Golden Eagles vs Iowa State Cyclones?

The spread opened at IOWAST -30.5 and is now IOWAST -31.5.

What is the current moneyline for USM Golden Eagles vs Iowa State Cyclones?

The current moneyline is USM +5000 / IOWAST -100000.

How far has the moneyline moved for USM Golden Eagles vs Iowa State Cyclones?

The moneyline opened at USM +5000 / IOWAST -100000 and is now USM +5000 / IOWAST -100000.

What is the current total for USM Golden Eagles vs Iowa State Cyclones?

The current total is 149.5.

How far has the total moved for USM Golden Eagles vs Iowa State Cyclones?

The total opened at 148.5 and is now 149.5.

Is the market taking the underdog in USM Golden Eagles vs Iowa State Cyclones?

Current market signal: Market Widening.

Is the market taking the favorite in USM Golden Eagles vs Iowa State Cyclones?

Current market signal: Market Steady.

Is the total dropping for USM Golden Eagles vs Iowa State Cyclones?

Current totals signal: Total Rising.

Is the total rising for USM Golden Eagles vs Iowa State Cyclones?

Current totals signal: Total Rising.

Where to watch USM Golden Eagles vs Iowa State Cyclones?

You can watch this game on ESPN+. For the latest broadcast details, see Where to Watch.

Where to stream USM Golden Eagles vs Iowa State Cyclones?

You can stream this game on ESPN+.

What is the best free prop bet for USM Golden Eagles vs Iowa State Cyclones?

Remi's Still Searching

What is the biggest matchup edge for USM Golden Eagles vs Iowa State Cyclones?

Southern Miss forced 22 turnovers with 15 steals in its opener, but Iowa State committed only 11 turnovers against Memphis and holds a major talent edge inside, where Pleta and Tre Singleton combined for 26 points and Singleton grabbed 11 rebounds.

REMI AI PERFORMANCE

CBB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement. We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

Matchup USM Golden Eagles vs. Iowa State Cyclones
Game Date November 06, 2026
Venue Hilton Coliseum
RECENT COMPLETED PICKS

AI CBB PAST PICKS

28-23 54.9% WIN
GAME
LEAN
WIN %
UNITS
RESULT
STNFRD@WVU
WVU -114
53.1%
3
WIN
BAYLOR@MINN
BAYLOR -3.5
54.1%
4
WIN
UCONN@DUKE
UCONN +5.5
57.0%
6
WIN
IOWA@ILL
ILL -6.5
56.4%
6
WIN
BAMA@MICH
MICH -8.5
56.3%
6
WIN
IOWA@NEB
NEB -1.5
54.5%
4
LOSS
ARK@ARIZ
ARIZ -7.5
56.3%
6
WIN
NEVADA@AUBURN
AUBURN -9.5
54.9%
5
LOSS
WICHST@TULSA
WICHST +3.5
54.8%
4
LOSS
TXTECH@BAMA
TXTECH -115
57.8%
6
LOSS
UK@IOWAST
IOWAST -4.5
53.5%
3
WIN
UNLV@TULSA
TULSA -4
54.7%
4
WIN
UCLA@UCONN
UCONN -4.5
55.1%
5
WIN
MIAMI@PURDUE
PURDUE -7.5
56.4%
6
WIN
HIGHPT@ARK
ARK -11.5
55.1%
5
LOSS
TEXAS@GONZAG
GONZAG -6
54.9%
4
LOSS
VCU@ILL
ILL -10.5
56.7%
6
WIN
MIAOH@TENN
MIAOH +11.5
56.4%
6
LOSS
MIZZOU@MIAMI
MIAMI -1.5
54.0%
3
WIN
SNCLRA@UK
SNCLRA +2.5
53.6%
3
WIN
FURMAN@UCONN
FURMAN +20.5
54.7%
4
WIN
PENN@ILL
PENN +25.5
55.6%
5
LOSS
MCNSE@VANDY
VANDY -11.5
53.8%
3
LOSS
SFLA@LVILLE
SFLA +4
55.4%
5
PUSH
HOWARD@MICH
ELLIOT CADEAU UNDER 1.5 THREE POINTERS MADE
54.6%
4
WIN
MIAOH@SMU
MIAOH +7
56.2%
6
WIN
NCST@TEXAS
NCST -113
56.7%
6
LOSS
DAYTON@VCU
VCU -3.5
56.5%
6
WIN
UVA@DUKE
UVA +7.5
53.5%
3
WIN
PURDUE@UCLA
PURDUE -7
53.3%
3
PUSH
PENN@HARV
HARV -2.5
56.2%
6
LOSS
SCARST@HOWARD
HOWARD -14.5
54.7%
4
WIN
IOWAST@ARIZ
ARIZ -3.5
54.1%
3
LOSS
XAVIER@UCONN
UCONN -15.5
54.1%
4
WIN
BU@LEHIGH
BU -2
54.2%
4
LOSS
TEMPLE@FAU
TEMPLE +1.5
54.9%
4
LOSS
UCSB@UCDAV
UCSB -5.5
54.8%
4
LOSS
BYU@WVU
WVU +4.5
56.9%
6
LOSS
MONTANA@PORTST
PORTST -3.5
56.3%
6
LOSS
UMASSLO@UMBC
UMASSLO +6.5
53.5%
3
LOSS
MNMTH@HOFSTRA
MNMTH +4
55.8%
5
LOSS
NEWORL@TXAMCC
TXAMCC -2
53.5%
3
WIN
TOWSON@HOFSTRA
HOFSTRA -3.5
54.9%
4
LOSS
NKY@WISCGB
NKY -2.5
54.3%
4
WIN
NIOWA@UIC
NIOWA -3.5
54.5%
4
WIN
NDAK@STTOM-MN
NDAK +12.5
54.3%
4
WIN
GWASH@LOYCHI
LOYCHI +10.5
54.3%
4
WIN
ALBANY@UMASSLO
UMASSLO -2.5
55.3%
5
WIN
PORT@SANFRAN
PORT +7.5
53.6%
3
LOSS
UNC@DUKE
DUKE -17
57.3%
7
LOSS
NIOWA@BRAD
NIOWA -4.5
56.1%
6
LOSS
Past performance is not a guarantee of future results. Picks are displayed for informational purposes only.