Blues vs Islanders Prediction — AI Finds CAN'T MISS NHL Lines & Props (Nov 22)

Updated: 2025-11-20T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props



Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Nov 22, 2025

Start Time: 3:30 PM EST​

Venue:

Islanders Record:

Blues Record:

OPENING ODDS

STL Moneyline:

NYI Moneyline:

STL Spread: 0

NYI Spread:

Over/Under:

STL
Betting Trends

NYI
Betting Trends

MATCHUP TRENDS

STL vs. NYI
Best Prop Bet

LIVE NHL ODDS

NHL ODDS COMPARISON

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St. Louis vs New York Prediction & Odds:
Free NHL Betting Insights for 11/22/25

St. Louis Blues NHL Preview

 St. Louis vs New York AI Prediction: Free NHL Betting Insights for Nov 22. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

New York Islanders NHL Preview

St. Louis vs. New York Prop Picks (AI)

Remi is pouring through tons of datapoints on each line. In fact, anytime the Blues and Islanders play there’s always several intriguing trends to key in on. Not to mention games played at in Nov can often follow normal, predictable patterns.

St. Louis vs. New York Prediction (AI)

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Remi, our AI sports genius, has been pouring over exorbitant amounts of data from every angle between the Blues and Islanders and using recursive machine learning and impressive AI to analyze the data to a single cover probability.

Interestingly enough, the data has been most keyed in on the trending factor human bettors regularly put on player performance factors between a Blues team going up against a possibly tired Islanders team. In reality, the true game analytics appear to reflect a moderate lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our NHL AI picks for FREE now.

Below is our current AI St. Louis vs New York picks, computer picks Blues vs Islanders, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
NHL 10/21 FLA@BOS GET FREE PICK NOW 7
NHL 10/21 CLB@DAL UNLOCK THIS PICK 1 INTEL Locked INTEL
NHL 10/21 SEA@WAS UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NHL schedule

Blues Betting Trends

Islanders Betting Trends

Blues vs. Islanders Matchup Trends

St. Louis vs. New York Game Info

St. Louis vs New York starts on November 22, 2025 at 3:30 PM EST.

Spread: New York
Moneyline: St. Louis , New York
Over/Under:

. Prices move—always shop for the best number.

See our latest NHL picks and odds pages for 2025 to compare prices before you bet.

St. Louis vs. New York Odds

AI algorithm Remi is pouring through loads of data points on each player. In fact, anytime the St. Louis vs New York trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme altitude almost always follow normal, predictable betting trends.

St. Louis vs New York Opening Odds

STL Moneyline:
NYI Moneyline:
STL Spread: 0
NYI Spread:
Over/Under:

St. Louis vs New York Live Odds

Games PTS ML SPR O/U
Oct 21, 2025 7:10PM EDT
San Jose Sharks
New York Islanders
10/21/25 7:10PM
Sharks
Islanders
+193
-222
+1.5 (-127)
-1.5 (+107)
O 6.5 (-111)
U 6.5 (-105)
Oct 21, 2025 7:10PM EDT
Vancouver Canucks
Pittsburgh Penguins
10/21/25 7:10PM
Canucks
Penguins
-109
-105
+1.5 (-270)
-1.5 (+222)
O 6 (-117)
U 6 (+101)
Oct 21, 2025 7:10PM EDT
Edmonton Oilers
Ottawa Senators
10/21/25 7:10PM
Oilers
Senators
-123
+109
-1.5 (+186)
+1.5 (-219)
O 6 (-105)
U 6 (-111)
Oct 21, 2025 7:10PM EDT
New Jersey Devils
Toronto Maple Leafs
10/21/25 7:10PM
Devils
Maple Leafs
+105
-119
+1.5 (-245)
-1.5 (+203)
O 5.5 (-116)
U 5.5 (+100)
Oct 21, 2025 7:10PM EDT
Seattle Kraken
Washington Capitals
10/21/25 7:10PM
Kraken
Capitals
+218
-252
+1.5 (-120)
-1.5 (+100)
O 6 (-110)
U 6 (-106)
Oct 21, 2025 7:40PM EDT
Florida Panthers
Boston Bruins
10/21/25 7:40PM
Panthers
Bruins
-155
+136
-1.5 (+170)
+1.5 (-195)
O 5.5 (-105)
U 5.5 (-111)
Oct 21, 2025 8:10PM EDT
Columbus Blue Jackets
Dallas Stars
10/21/25 8:10PM
Blue Jackets
Stars
+165
-189
+1.5 (-156)
-1.5 (+136)
O 6 (-125)
U 6 (+109)
Oct 21, 2025 8:10PM EDT
Los Angeles Kings
St Louis Blues
10/21/25 8:10PM
Kings
Blues
+114
-129
+1.5 (-225)
-1.5 (+189)
O 5.5 (-123)
U 5.5 (+107)
Oct 21, 2025 8:10PM EDT
Anaheim Ducks
Nashville Predators
10/21/25 8:10PM
Ducks
Predators
+117
-133
+1.5 (-217)
-1.5 (+185)
O 6 (-115)
U 6 (-101)
Oct 22, 2025 7:00PM EDT
Minnesota Wild
New Jersey Devils
10/22/25 7PM
Wild
Devils
+110
-130
+1.5 (-245)
-1.5 (+200)
O 5.5 (-125)
U 5.5 (+105)
Oct 22, 2025 7:30PM EDT
Detroit Red Wings
Buffalo Sabres
10/22/25 7:30PM
Red Wings
Sabres
+101
-115
+1.5 (-250)
-1.5 (+205)
O 6 (-104)
U 6 (-112)
Oct 22, 2025 8:30PM EDT
Montreal Canadiens
Calgary Flames
10/22/25 8:30PM
Canadiens
Flames
 
+113
 
+1.5 (-245)
O 5.5 (-128)
U 5.5 (+112)

NHL Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers St. Louis Blues vs. New York Islanders on November 22, 2025 at .
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our NHL odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
MIN@WAS WAS -120 56.2% 3 WIN
WPG@PHI WPG -132 56.7% 3 WIN
NYR@TOR TOR -133 58.6% 4 WIN
CGY@UTA OVER 6 53.8% 3 LOSS
OTT@BUF OTT -108 53.1% 3 LOSS
FLA@DET AARON EKBLAD OVER 0.5 POINTS 54.0% 4 LOSS
LA@MIN LA -110 56.0% 5 LOSS
STL@VAN VAN -121 54.6% 4 LOSS
BUF@BOS BOS -114 54.9% 3 WIN
ANA@SEA SEA -125 54.2% 3 WIN
ANA@SEA TROY TERRY OVER 0.5 POINTS 53.3% 3 LOSS
BOS@WAS ALEX OVECHKIN TO SCORE A GOAL 41.4% 2 LOSS
FLA@EDM MATTHEW TKACHUK OVER 0.5 ASSTS 53.70% 3 WIN
FLA@EDM RYAN NUGENT-HOPKINS OVER 1.5 SHOTS ON GOAL 54.50% 4 LOSS
EDM@FLA ALEKSANDER BARKOV UNDER 11.5 FACEOFFS WON 53.00% 3 LOSS
EDM@FLA ALEKSANDER BARKOV UNDER 20.5 MINUTES ON THE ICE 54.00% 4 LOSS
EDM@DAL DAL -110 53.80% 3 LOSS
EDM@DAL DAL -125 56.70% 3 WIN
TOR@FLA MAX PACIORETTY UNDER 1.5 SHOTS ON GOAL 55.60% 5 LOSS
TOR@FLA WILLIAM NYLANDER UNDER 2.5 SHOTS ON GOAL 54.90% 4 LOSS
CAR@WAS WAS +140 47.70% 3 WIN
WPG@STL STL -110 54.80% 4 WIN
WPG@STL UNDER 5.5 55.70% 4 LOSS
CGY@LA MACKENZIE WEEGAR OVER 2.5 BLOCKS 53.10% 3 WIN
TB@NYR TB +110 49.80% 3 LOSS
SJ@VAN ALEXANDER GEORGIEV UNDER 24.5 SAVES 54.50% 4 LOSS
BUF@TB OVER 6.5 53.90% 3 WIN
NYI@PHI PHI -110 54.00% 3 WIN
LV@EDM RYAN NUGENT-HOPKINS OVER 1.5 SHOTS ON GOAL 53.00% 3 WIN
EDM@ANA OVER 6 54.20% 3 LOSS
CAR@BOS OVER 5.5 54.00% 3 WIN
NYR@NJ NJ -125 57.30% 4 WIN
COL@CLB OVER 6.5 53.80% 3 WIN
LA@UTA LA -125 54.70% 3 WIN
WPG@LV LV -120 54.80% 3 LOSS
MIN@NJ UNDER 5.5 53.80% 3 WIN
NSH@PHI PHI -120 55.00% 3 WIN
OTT@BUF OVER 6 54.00% 3 LOSS
CHI@SJ CHI +105 51.60% 3 LOSS
WAS@LA WAS +105 51.20% 3 LOSS
TB@CAR CAR -130 56.40% 3 WIN
NSH@BOS BOS -125 55.20% 3 LOSS
MIN@SEA SEA -120 54.60% 3 LOSS
SJ@TOR OVER 6 54.80% 3 LOSS
BUF@MON MON -110 54.70% 4 WIN
BOS@PIT PIT -120 54.90% 3 LOSS
LA@STL STL -110 53.70% 3 WIN
LA@DAL DAL -125 56.40% 4 WIN
PIT@PHI PHI -116 54.20% 3 WIN
DET@MIN MIN -115 54.20% 3 LOSS
MIN@DET DET -130 58.00% 3 LOSS