Away Team
Record 4-2
Last 5 4-1 last five
ATS 4-2-0 ATS
Road 1-2 road
Standings
NFL Game Preview
Schedule
Kickoff Countdown
6d 09:24:06
Start Time 4:05 PM EST
Date October 25, 2026
Venue State Farm Stadium
Where To Watch CBS
Where To Stream Paramount+
Season Series First meeting of 2026 season.

Denver brings a 4-2 record and four spread covers into Glendale, but its sputtering passing attack makes laying points uncomfortable. Arizona just upset the Rams, and injuries in both secondaries and backfields complicate this matchup.

Home Team
Record 2-4
Last 5 1-4 last five
ATS 3-3-0 ATS
Home 0-2 home
Analysis Updated: 5:55 AM ET
Injuries Checked: 5:50 AM ET
Odds Updated: 6:34 AM ET

Betting Snapshot

Spread
ARI +4.5
Open: ARI +7.5
Market Tightening

Spread Movement

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Odds Updated: 10/19 6:34 AM ET
Moneyline
ARI +170
Open: ARI +285
Favorite Taking Support

Moneyline Movement

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Odds Updated: 10/19 6:34 AM ET
Total
42.5
Open: 43.5
Total Dropping

Total Movement

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Odds Updated: 10/19 6:34 AM ET

Best Free Prop Pick

FREE PROP
Remi's Still Searching
Bo Nix Under 199.5 passing yards aligns with consecutive outputs of 123 and 107. Bo Nix Under 199.5 passing yards benefits from a run-supported Denver approach to Arizona. Bo Nix Under 199.5 passing yards fits a script built around Denver defense and ball control.

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Odds Comparison Center

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Best Home Spread
FanDuel | ARI +4.5
Best Home Moneyline
FanDuel | ARI +184
Best Over Line
DraftKings | 42.5
Best Away Spread
BetMGM | DEN -4
Best Away Moneyline
DraftKings | DEN -205
Best Under Line
FanDuel | 43.5
Updated 6:34 AM ET
Sportsbook Spread Moneyline Total
FanDuelDEN -4.5
ARI +4.5
DEN -220
ARI +184
O 43.5
U 43.5
DraftKingsDEN -4.5
ARI +4.5
DEN -205
ARI +170
O 42.5
U 42.5
BetMGMDEN -4
ARI +4
DEN -210
ARI +175
O 43
U 43
BetRiversDEN -4
ARI +4
DEN -225
ARI +180
O 42.5
U 42.5
BovadaDEN -4
ARI +4
DEN -210
ARI +175
O 43
U 43
BetOnline.agDEN -4
ARI +4
DEN -205
ARI +177
O 43
U 43
LowVig.agDEN -4
ARI +4
DEN -205
ARI +177
O 43
U 43
MyBookie.ag—DEN -222
ARI +169
—
BetUSDEN -4
ARI +4
—O 43
U 43
CaesarsDEN -4
ARI +4
DEN -218
ARI +180
O 43
U 43

Injury Report

Denver was without cornerback Patrick Surtain II and safety Talanoa Hufanga against Seattle. Surtain has been targeting a return, while Hufanga has been expected to miss additional time; corner Riley Moss has dealt with a rib injury. Arizona rookie running back Jeremiyah Love missed the Rams game with an ankle injury, leaving the backfield workload to Tyler Allgeier and Bam Knight. Week 7 practice reports and final designations will determine the true matchup impact.

Key Players

Denver
Bo Nix
Nix threw for 107 yards against Seattle after 123 against the Chargers.
Arizona
Trey McBride
McBride remains a central Arizona receiving option against an injury-affected Denver secondary.

Key Matchup Edge

Denver has the more dependable defensive profile and a 4-2 ATS mark, but its offense has scored just 17 and 23 points in consecutive wins. Arizona has allowed explosive scoring in losses, yet Denver must generate sustained drives before its favorite status offers value. Watch the injury report before treating this as a routine road cover.

3 Things to Watch

  • Surtain availability against Arizona receiving targets
  • Denver passing efficiency and third downs
  • Arizona red-zone touchdowns instead of field goals

Betting Breakdown

Denver visits Arizona in Week 7 with the better record and a modest market advantage, but recent scoring shows why the handicap is not straightforward. The Broncos improved to 4-2 with a 17-14 overtime win against Seattle, following a 23-17 victory over the Chargers. Both games rewarded Denver backers against the spread, while quarterback Bo Nix combined for only 230 passing yards across the two contests. That leaves bettors weighing defensive reliability against limited offensive separation. Arizona snapped a four-game losing streak by beating the Rams 18-16 on six Chad Ryland field goals, a result that helped the Cardinals reach 2-4 and cover the number. Still, six field goals without a touchdown also illustrated their finishing problems. Denver's secondary injuries could create receiving opportunities, particularly if Patrick Surtain II remains limited, while Arizona's run game faces questions following Jeremiyah Love's ankle absence. One tracked spread shifted from Denver -7 to approximately -5.5, making price discipline important. The under also deserves consideration given Denver's five unders in six games, although Arizona's earlier defensive breakdowns make this far from automatic.

Denver Betting Outlook

Denver comes into Glendale having won four of its last five, with victories over Jacksonville, the Rams, the Chargers and Seattle. Its 4-2 ATS mark reflects a team that has frequently delivered against expectations even when the offense is uneven. Nix has thrown for 123 yards or fewer in each of his last two outings, so a multi-score cover cannot be assumed from quarterback production alone. J.K. Dobbins leads the rushing attack, and Denver's defense has repeatedly kept games manageable. A weakened secondary is the main counterargument, particularly if Arizona tests coverage depth. The road split is 1-2, another reason to distinguish Denver's straight-up prospects from spread value.

Arizona Betting Outlook

Arizona returns home after a dramatic 18-16 road win over the Rams, ending a four-game slide and improving to 2-4. The Cardinals are 3-3 ATS, with their recent cover built on defense, field position and Chad Ryland's six successful field goals. The concern is touchdown creation: moving the ball without finishing drives leaves little margin against a disciplined Denver defense. Jeremiyah Love missed the Rams game with an ankle problem, and his status will shape the workload for Tyler Allgeier and Bam Knight. Trey McBride offers a receiving focal point, especially if Denver is missing key defensive backs. Arizona is 0-2 at home, but the underdog price offers a different calculation from simply picking a winner.

Latest Team Buzz

Denver Broncos vs Arizona Cardinals FAQ

What is the current spread for Denver Broncos vs Arizona Cardinals?

The current home spread is ARI +4.5, while the away spread is DEN -4.5.

How far has the spread moved for Denver Broncos vs Arizona Cardinals?

The spread opened at ARI +7.5 and is now ARI +4.5.

What is the current moneyline for Denver Broncos vs Arizona Cardinals?

The current moneyline is DEN -205 / ARI +170.

How far has the moneyline moved for Denver Broncos vs Arizona Cardinals?

The moneyline opened at DEN -360 / ARI +285 and is now DEN -205 / ARI +170.

What is the current total for Denver Broncos vs Arizona Cardinals?

The current total is 42.5.

How far has the total moved for Denver Broncos vs Arizona Cardinals?

The total opened at 43.5 and is now 42.5.

Is the market taking the underdog in Denver Broncos vs Arizona Cardinals?

Current market signal: Market Tightening.

Is the market taking the favorite in Denver Broncos vs Arizona Cardinals?

Current market signal: Favorite Taking Support.

Is the total dropping for Denver Broncos vs Arizona Cardinals?

Current totals signal: Total Dropping.

Is the total rising for Denver Broncos vs Arizona Cardinals?

Current totals signal: Total Dropping.

Where to watch Denver Broncos vs Arizona Cardinals?

You can watch this game on CBS. For the latest broadcast details, see Where to Watch.

Where to stream Denver Broncos vs Arizona Cardinals?

You can stream this game on Paramount+.

What is the best free prop bet for Denver Broncos vs Arizona Cardinals?

Remi's Still Searching

What is the biggest matchup edge for Denver Broncos vs Arizona Cardinals?

Denver has the more dependable defensive profile and a 4-2 ATS mark, but its offense has scored just 17 and 23 points in consecutive wins. Arizona has allowed explosive scoring in losses, yet Denver must generate sustained drives before its favorite status offers value. Watch the injury report before treating this as a routine road cover.

REMI AI PERFORMANCE

NFL Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement. We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

Matchup Denver Broncos vs. Arizona Cardinals
Game Date October 25, 2026
Venue State Farm Stadium
RECENT COMPLETED PICKS

AI NFL PAST PICKS

24-27 47.1% WIN
GAME
LEAN
WIN %
UNITS
RESULT
DEN@LAC
DEN -3
58.0%
8
WIN
DEN@LAC
UNDER 42.5
60.0%
9
WIN
TB@DAL
TB +9.5
57.7%
6
WIN
KC@LV
KC -4.5
56.5%
6
LOSS
DEN@SF
OVER 47.5
56.2%
6
LOSS
ARI@SF
UNDER 48.5
57.0%
6
LOSS
NYJ@DET
DET -6.5
57.2%
7
WIN
CAR@ATL
CAR -2
57.1%
7
WIN
CLE@TB
UNDER 41.5
56.0%
6
LOSS
CLE@JAC
UNDER 40.5
56.7%
6
LOSS
DAL@NYG
DAK PRESCOTT UNDER 0.5 INTERCEPTIONS
56.4%
6
LOSS
SF@LAR
BLAKE CORUM OVER 0.5 RECEPTIONS
56.2%
6
LOSS
SEA@NE
AJ BARNER UNDER 2.5 RECEPTIONS
53.8%
3
LOSS
SEA@NE
STEFON DIGGS OVER 4.5 RECEPTIONS
57.5%
7
LOSS
SEA@NE
SAM DARNOLD OVER 2.5 CARRIES
54.2%
4
LOSS
SEA@NE
DRAKE MAYE TO THROW AN INT
55.5%
5
WIN
LAR@SEA
SAM DARNOLD TO THROW AN INT
55.9%
5
LOSS
NE@DEN
DRAKE MAYE OVER 29.5 PASS ATT
54.3%
4
LOSS
NE@DEN
DRAKE MAYE TO THROW AN INT
55.4%
5
LOSS
NE@DEN
DEN +4
55.0%
4
WIN
HOU@NE
HOU +3.5
56.0%
6
LOSS
HOU@NE
DRAKE MAYE OVER 0.5 INT
55.1%
5
WIN
LAR@CHI
KYREN WILLIAMS OVER 59.5 RUSH YDS
55.5%
5
WIN
SF@SEA
JAUAN JENNINGS OVER 3.5 RECEPTIONS
56.8%
6
LOSS
BUF@DEN
BO NIX OVER 243.5 PASS + RUSH YDS
55.2%
5
WIN
SF@SEA
SF +7
56.8%
6
LOSS
HOU@PIT
UNDER 38.5
53.4%
2
WIN
HOU@PIT
AARON RODGERS UNDER 21.5 PASS COMP
54.5%
4
WIN
LAC@NE
DRAKE MAYE OVER 0.5 INT THROWN
56.1%
6
WIN
BUF@JAC
TRAVIS ETIENNE UNDER 81.5 RUSH + RECV YDS
54.2%
4
LOSS
SF@PHI
SF +6.5
54.7%
4
WIN
LAC@NE
LAC +3.5
57.1%
7
LOSS
LAR@CAR
MATTHEW STAFFORD UNDER 33.5 PASS ATT
53.5%
3
LOSS
GB@CHI
CALEB WILLIAMS UNDER 0.5 INT THROWN
55.1%
5
LOSS
BAL@PIT
DERRICK HENRY OVER 99.5 RUSH + REC YDS
55.9%
5
WIN
DET@CHI
JAHMYR GIBBS ANYTIME TD
56.8%
6
WIN
IND@HOU
CJ STROUD OVER 221.5 PASS + RUSH YDS
55.4%
5
LOSS
TEN@JAC
JAC -13.5
56.3%
6
WIN
CLE@CIN
CIN -7.5
53.8%
3
LOSS
DAL@NYG
OVER 49.5
54.6%
4
WIN
CAR@TB
BRYCE YOUNG UNDER 0.5 INT
55.2%
5
LOSS
SEA@SF
KENNETH WALKER III UNDER 11.5 RUSH ATT
55.3%
5
LOSS
CAR@TB
BAKER MAYFIELD OVER 0.5 INT
54.1%
4
WIN
SEA@SF
CHRISTIAN MCCAFFREY OVER 5.5 RECEPTIONS
56.7%
6
WIN
LAR@ATL
KYLE PITS OVER 54.5 RECV YDS
55.7%
5
LOSS
LAR@ATL
BIJAN ROBINSON UNDER 44.5 RECV YDS
54.3%
4
WIN
CHI@SF
CALEB WILLIAMS OVER 224.5 PASS YDS
54.1%
4
WIN
JAC@IND
MICHAEL PITTMAN OVER 49.5 RECV YDS
55.2%
5
LOSS
PIT@CLE
CLE +4.5
56.9%
6
WIN
ARI@CIN
CIN -7
58.8%
8
WIN
TB@MIA
TB -4.5
55.2%
5
LOSS
Past performance is not a guarantee of future results. Picks are displayed for informational purposes only.