Away Team
Record 0-0
Last 5 4-1 last five
ATS 0-0-0 ATS
Road 0-0 road
Standings
NFL Game Preview
Schedule
Kickoff Countdown
20d 10:29:07
Start Time 1:00 PM EST
Date September 27, 2026
Venue Lucas Oil Stadium
Where To Watch CBS
Where To Stream Paramount+
Season Series Series tied 0-0.

Houston enters Week 3 as a slight road favorite after winning five straight against Indianapolis, but Lucas Oil and a rebuilt Colts secondary keep the spread tight. Tank Dell's guaranteed absence adds pressure to Houston's pass-game depth.

Home Team
Record 0-0
Last 5 0-5 last five
ATS 0-0-0 ATS
Home 0-0 home
Analysis Updated: 7:52 AM ET
Injuries Checked: 7:50 AM ET
Odds Updated: 2:19 AM ET

Betting Snapshot

Spread
IND +1.5
Open: IND +1.5
Market Steady

Spread Movement

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Odds Updated: 9/7 2:19 AM ET
Moneyline
IND +105
Open: IND +110
Favorite Taking Support

Moneyline Movement

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Odds Updated: 9/7 2:19 AM ET
Total
45.5
Open: 45.5
Total Steady

Total Movement

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Odds Updated: 9/7 2:19 AM ET

Best Free Prop Pick

FREE PROP
Remi's Still Searching
Jonathan Taylor Under 87.5 rushing yards: Houston held him to 55.5 per meeting last season. Jonathan Taylor Under 87.5 rushing yards: he averaged 3.2 per carry against Houston in 2025. Jonathan Taylor Under 87.5 rushing yards: Houston's slight-favorite status could force Indianapolis toward more passing.

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Odds Comparison Center

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Best Home Spread
DraftKings | IND +1.5
Best Home Moneyline
DraftKings | IND +105
Best Over Line
Caesars | 43.5
Best Away Spread
Caesars | HOU -1
Best Away Moneyline
Caesars | HOU -120
Best Under Line
DraftKings | 45.5
Updated 2:19 AM ET
Sportsbook Spread Moneyline Total
DraftKingsHOU -1.5
IND +1.5
HOU -125
IND +105
O 45.5
U 45.5
BetUSHOU -1.5
IND +1.5
O 45.5
U 45.5
CaesarsHOU -1
IND +1
HOU -120
IND -110
O 43.5
U 43.5

Injury Report

Houston wideout Tank Dell was placed on injured reserve with a designation to return and must miss at least the first four games, making him unavailable for Week 3. Indianapolis tight end Will Mallory is also on injured reserve designated to return and cannot play this matchup. No other Week 3 game-status designations are official this far out.

Key Players

Houston
C.J. Stroud
Threw for 3,041 yards with 19 touchdowns and eight interceptions in 14 games.
Indianapolis
Jonathan Taylor
Rushed for 1,585 yards and 18 touchdowns on 323 carries in 2025.

Key Matchup Edge

Houston's defensive front is the clearest betting edge. The Texans allowed 4.0 yards per carry and posted 47 sacks last season, while Taylor managed only 111 rushing yards on 35 carries across two 2025 meetings. If Houston wins early downs again, Indianapolis will be forced to lean more heavily on Daniel Jones against a deep secondary.

3 Things to Watch

  • Taylor efficiency against Houston's front
  • Stroud versus Gardner and Ward
  • Dell's absence reshaping Houston targets

Betting Breakdown

Houston's short road-favorite price is built on continuity where it matters most: a defense that powered a 12-5 season, generated 47 sacks and held opponents to 4.0 yards per rush in 2025. That profile has translated directly to this matchup, with the Texans winning five straight against Indianapolis and limiting Jonathan Taylor to 111 rushing yards on 35 carries across the two meetings last season. The Colts still bring real home-field resistance after going 6-3 at Lucas Oil Stadium in 2025, and their offense remains dangerous behind Taylor, Daniel Jones, Tyler Warren and newly added Keenan Allen. The betting tension is whether Indianapolis can stay ahead of the chains long enough to protect Jones from Houston's pass rush. Tank Dell's Week 3 absence narrows Houston's receiving rotation, but Nico Collins and Dalton Schultz still give C.J. Stroud reliable targets. With the total around 45.5, Houston's defensive edge and recent series control are the stronger early anchors.

Houston Betting Outlook

Houston enters 2026 with a 0-0 record after a 12-5 regular season and a 5-3 road mark in 2025. The Texans' identity remains defense-first after allowing just 4.0 yards per carry and recording 47 sacks, led by Will Anderson Jr. and Danielle Hunter. Offensively, C.J. Stroud threw for 3,041 yards and 19 touchdowns in 14 games, with Nico Collins posting another 1,000-yard season. The addition of David Montgomery should strengthen short-yardage and early-down consistency. Tank Dell's required four-game injured-reserve absence removes an explosive option, so Houston's ability to create efficient offense without overloading Stroud will matter against Indianapolis' upgraded secondary.

Indianapolis Betting Outlook

Indianapolis starts 2026 at 0-0 after finishing 8-9 last season, including a strong 6-3 home record. Jonathan Taylor remains the centerpiece after rushing for 1,585 yards and 18 touchdowns, while Daniel Jones produced 3,101 passing yards with 19 touchdowns and eight interceptions. The Colts added Keenan Allen to a receiving group featuring Alec Pierce, Josh Downs and Tyler Warren, giving Jones more route-winning options underneath. Defensively, a healthier Sauce Gardner and Charvarius Ward pairing raises the ceiling of the secondary. The concern is matchup history: Houston has won five straight in the series, and Taylor was held below 90 rushing yards in both 2025 meetings.

Latest Team Buzz

Houston Texans vs Indianapolis Colts FAQ

What is the current spread for Houston Texans vs Indianapolis Colts?

The current home spread is IND +1.5, while the away spread is HOU -1.5.

How far has the spread moved for Houston Texans vs Indianapolis Colts?

The spread opened at IND +1.5 and is now IND +1.5.

What is the current moneyline for Houston Texans vs Indianapolis Colts?

The current moneyline is HOU -125 / IND +105.

How far has the moneyline moved for Houston Texans vs Indianapolis Colts?

The moneyline opened at HOU -130 / IND +110 and is now HOU -125 / IND +105.

What is the current total for Houston Texans vs Indianapolis Colts?

The current total is 45.5.

How far has the total moved for Houston Texans vs Indianapolis Colts?

The total opened at 45.5 and is now 45.5.

Is the market taking the underdog in Houston Texans vs Indianapolis Colts?

Current market signal: Market Steady.

Is the market taking the favorite in Houston Texans vs Indianapolis Colts?

Current market signal: Favorite Taking Support.

Is the total dropping for Houston Texans vs Indianapolis Colts?

Current totals signal: Total Steady.

Is the total rising for Houston Texans vs Indianapolis Colts?

Current totals signal: Total Steady.

Where to watch Houston Texans vs Indianapolis Colts?

You can watch this game on CBS. For the latest broadcast details, see Where to Watch.

Where to stream Houston Texans vs Indianapolis Colts?

You can stream this game on Paramount+.

What is the best free prop bet for Houston Texans vs Indianapolis Colts?

Remi's Still Searching

What is the biggest matchup edge for Houston Texans vs Indianapolis Colts?

Houston's defensive front is the clearest betting edge. The Texans allowed 4.0 yards per carry and posted 47 sacks last season, while Taylor managed only 111 rushing yards on 35 carries across two 2025 meetings. If Houston wins early downs again, Indianapolis will be forced to lean more heavily on Daniel Jones against a deep secondary.

REMI AI PERFORMANCE

NFL Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement. We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

Matchup Houston Texans vs. Indianapolis Colts
Game Date September 27, 2026
Venue Lucas Oil Stadium
RECENT COMPLETED PICKS

AI NFL PAST PICKS

29-22 56.9% WIN
GAME
LEAN
WIN %
UNITS
RESULT
HOU@NE
DRAKE MAYE OVER 0.5 INT
55.1%
5
WIN
LAR@CHI
KYREN WILLIAMS OVER 59.5 RUSH YDS
55.5%
5
WIN
SF@SEA
JAUAN JENNINGS OVER 3.5 RECEPTIONS
56.8%
6
LOSS
BUF@DEN
BO NIX OVER 243.5 PASS + RUSH YDS
55.2%
5
WIN
SF@SEA
SF +7
56.8%
6
LOSS
HOU@PIT
UNDER 38.5
53.4%
2
WIN
HOU@PIT
AARON RODGERS UNDER 21.5 PASS COMP
54.5%
4
WIN
LAC@NE
DRAKE MAYE OVER 0.5 INT THROWN
56.1%
6
WIN
BUF@JAC
TRAVIS ETIENNE UNDER 81.5 RUSH + RECV YDS
54.2%
4
LOSS
SF@PHI
SF +6.5
54.7%
4
WIN
LAC@NE
LAC +3.5
57.1%
7
LOSS
LAR@CAR
MATTHEW STAFFORD UNDER 33.5 PASS ATT
53.5%
3
LOSS
GB@CHI
CALEB WILLIAMS UNDER 0.5 INT THROWN
55.1%
5
LOSS
BAL@PIT
DERRICK HENRY OVER 99.5 RUSH + REC YDS
55.9%
5
WIN
DET@CHI
JAHMYR GIBBS ANYTIME TD
56.8%
6
WIN
IND@HOU
CJ STROUD OVER 221.5 PASS + RUSH YDS
55.4%
5
LOSS
TEN@JAC
JAC -13.5
56.3%
6
WIN
CLE@CIN
CIN -7.5
53.8%
3
LOSS
DAL@NYG
OVER 49.5
54.6%
4
WIN
CAR@TB
BRYCE YOUNG UNDER 0.5 INT
55.2%
5
LOSS
SEA@SF
KENNETH WALKER III UNDER 11.5 RUSH ATT
55.3%
5
LOSS
CAR@TB
BAKER MAYFIELD OVER 0.5 INT
54.1%
4
WIN
SEA@SF
CHRISTIAN MCCAFFREY OVER 5.5 RECEPTIONS
56.7%
6
WIN
LAR@ATL
KYLE PITS OVER 54.5 RECV YDS
55.7%
5
LOSS
LAR@ATL
BIJAN ROBINSON UNDER 44.5 RECV YDS
54.3%
4
WIN
CHI@SF
CALEB WILLIAMS OVER 224.5 PASS YDS
54.1%
4
WIN
JAC@IND
MICHAEL PITTMAN OVER 49.5 RECV YDS
55.2%
5
LOSS
PIT@CLE
CLE +4.5
56.9%
6
WIN
ARI@CIN
CIN -7
58.8%
8
WIN
TB@MIA
TB -4.5
55.2%
5
LOSS
NYG@LV
NYG -2
54.3%
4
WIN
NE@NYJ
NE -13.5
53.9%
3
WIN
NO@TEN
NO -1
56.0%
5
WIN
NYG@LV
UNDER 41.5
53.7%
3
LOSS
HOU@LAC
CJ STROUD OVER 0.5 INT
55.5%
5
WIN
DAL@WAS
DAL -8.5
54.1%
4
LOSS
DEN@KC
RJ HARVEY ANYTIME TD
54.4%
4
WIN
DAL@WAS
TERRY MCLAURIN ANYTIME TD
53.9%
3
LOSS
SF@IND
BROCK PURDY OVER 0.5 INT
55.2%
5
WIN
SF@IND
MICHAEL PITTMAN JR OVER 3.5 RECEPTIONS
54.2%
4
WIN
SF@IND
SF -4.5
56.8%
6
WIN
LV@HOU
NICO COLLINS ANYTIME TD
56.3%
6
LOSS
LAC@DAL
JAVONTE WILLIAMS UNDER 82.5 RUSH + RECV YDS
55.2%
5
WIN
JAC@DEN
TREVOR LAWRENCE UNDER 251.5 PASS + RUSH YDS
57.4%
7
LOSS
LV@HOU
HOU -14
54.6%
4
LOSS
BUF@CLE
CLE +10.5
54.9%
4
WIN
MIN@NYG
MIN -2.5
56.3%
6
WIN
TB@CAR
TB -3
53.1%
3
LOSS
JAC@DEN
DEN -3.5
53.6%
3
LOSS
KC@TEN
KC -2.5
54.6%
4
LOSS
NE@BAL
NE +3.5
56.4%
6
WIN
Past performance is not a guarantee of future results. Picks are displayed for informational purposes only.