Away Team
Record 0-0
Last 5 5-0 last five
ATS 0-0 ATS
Road 0-0 road
Standings
NFL Game Preview
Schedule
Kickoff Countdown
13d 08:10:29
Start Time 4:25 PM EST
Date September 20, 2026
Venue State Farm Stadium
Where To Watch FOX
Where To Stream FOX One
Season Series Series tied 0-0.

Seattle opens as a double-digit road favorite in a divisional rematch it dominated last season, while Arizona enters with James Conner unavailable and a 1-7 home ATS mark from 2025.

Home Team
Record 0-0
Last 5 0-5 last five
ATS 0-0 ATS
Home 0-0 home
Analysis Updated: 7:56 AM ET
Injuries Checked: 7:53 AM ET
Odds Updated: 8:04 AM ET

Betting Snapshot

Spread
ARI +10
Open: ARI +10
Market Steady

Spread Movement

Loading line history...
Odds Updated: 9/7 8:04 AM ET
Moneyline
ARI +400
Open: ARI +390
Dog Taking Support

Moneyline Movement

Loading line history...
Odds Updated: 9/7 8:04 AM ET
Total
44.5
Open: 44.5
Total Steady

Total Movement

Loading line history...
Odds Updated: 9/7 8:04 AM ET

Best Free Prop Pick

FREE PROP
Remi's Still Searching
Jaxon Smith-Njigba Over 79.5 receiving yards matches his 1,793-yard, 119-catch 2025 volume. Jaxon Smith-Njigba Over 79.5 receiving yards targets Arizona after 172 yards in two 2025 meetings. Jaxon Smith-Njigba Over 79.5 receiving yards benefits from Seattle's concentrated passing-game usage.

This page gives you one free prop. Upgrade for premium sides, totals, more props, and the full daily AI board.

Unlock Premium AI Picks

Odds Comparison Center

Shop for the best lines in one place.

Best Home Spread
DraftKings | ARI +10
Best Home Moneyline
DraftKings | ARI +400
Best Over Line
Caesars | 44
Best Away Spread
Caesars | SEA -9.5
Best Away Moneyline
Caesars | SEA -480
Best Under Line
DraftKings | 44.5
Updated 8:04 AM ET
Sportsbook Spread Moneyline Total
DraftKingsSEA -10
ARI +10
SEA -535
ARI +400
O 44.5
U 44.5
MyBookie.agSEA -10
ARI +10
SEA -575
ARI +380
O 44.5
U 44.5
BetUSSEA -10
ARI +10
O 44.5
U 44.5
CaesarsSEA -9.5
ARI +9.5
SEA -480
ARI +390
O 44
U 44

Injury Report

Seattle running back Zach Charbonnet is on reserve/PUP after offseason ACL surgery, ruling him out through at least Week 4 and removing a 12-touchdown 2025 finisher from the backfield. Arizona will also miss veteran James Conner, placed on injured reserve with a designation to return after Week 4. Rookie Jeremiyah Love has been recovering from an ankle issue but was trending toward Week 1 availability.

Key Players

Seattle
Jaxon Smith-Njigba
Led the NFL with 1,793 receiving yards and averaged 105.5 per game in 2025.
Arizona
Trey McBride
Set an NFL tight end record with 126 receptions in 2025.

Key Matchup Edge

Seattle owns the clearest edge through Jaxon Smith-Njigba against Arizona's secondary. He led the NFL in receiving yards and produced 172 yards across two Cardinals games last season. With Seattle laying 10, sustained chunk gains can create separation without requiring high play volume, while Arizona's offense faces the league's best 2025 scoring defense.

3 Things to Watch

  • Seattle pressure against Jacoby Brissett
  • Arizona's plan for Smith-Njigba
  • Early-down efficiency with depleted backfields

Betting Breakdown

Seattle enters this NFC West matchup as a 10-point road favorite with the total at 44.5, a number that reflects the gap between the defending champions and a Cardinals team coming off a 3-14 season. The Seahawks finished 2025 at 14-3, went 8-1 on the road and led the NFL in scoring defense at 17.2 points allowed per game. Arizona was 1-7 at home and 6-11 ATS, while Seattle posted a 12-5 regular-season ATS record. The matchup history also leans heavily toward Seattle, which has won four straight in the series and swept Arizona last year by scores of 23-20 and 44-22. Jaxon Smith-Njigba remains the primary matchup stressor after leading the league with 1,793 receiving yards, while Trey McBride gives Arizona a reliable counter after a record-setting 126-catch season. Backfield injuries matter on both sides, but James Conner's absence puts more pressure on Arizona to stay efficient against a championship-caliber defense.

Seattle Betting Outlook

Seattle brings the stronger recent profile after finishing 14-3 in 2025 and closing the season with a championship. The Seahawks went 8-1 on the road, scored 28.4 points per game and allowed an NFL-low 17.2. Jaxon Smith-Njigba is the centerpiece after a 1,793-yard season and 172 receiving yards across two meetings with Arizona. The main personnel concern is Zach Charbonnet's reserve/PUP status, which removes last season's 12-touchdown rushing leader from the rotation. For bettors, the question is not whether Seattle owns the matchup edge, but whether its passing game and defense can create enough margin to justify laying 10 points on the road.

Arizona Betting Outlook

Arizona starts 2026 trying to reset after a 3-14 season that included a 1-7 home record and a 6-11 ATS finish. Jacoby Brissett returns after throwing for 3,366 yards with 23 touchdowns and eight interceptions, while Trey McBride remains the offense's most bankable target after an NFL-record 126 receptions for a tight end. James Conner is unavailable on injured reserve, increasing the importance of Tyler Allgeier and Jeremiyah Love in the backfield. Arizona must protect Brissett, sustain drives and prevent Seattle's explosive passing game from creating early separation. Getting 10 points at home is meaningful, but the Cardinals need cleaner efficiency than they showed throughout 2025.

Latest Team Buzz

Seattle Seahawks vs Arizona Cardinals FAQ

What is the current spread for Seattle Seahawks vs Arizona Cardinals?

The current home spread is ARI +10, while the away spread is SEA -10.

How far has the spread moved for Seattle Seahawks vs Arizona Cardinals?

The spread opened at ARI +10 and is now ARI +10.

What is the current moneyline for Seattle Seahawks vs Arizona Cardinals?

The current moneyline is SEA -535 / ARI +400.

How far has the moneyline moved for Seattle Seahawks vs Arizona Cardinals?

The moneyline opened at SEA -520 / ARI +390 and is now SEA -535 / ARI +400.

What is the current total for Seattle Seahawks vs Arizona Cardinals?

The current total is 44.5.

How far has the total moved for Seattle Seahawks vs Arizona Cardinals?

The total opened at 44.5 and is now 44.5.

Is the market taking the underdog in Seattle Seahawks vs Arizona Cardinals?

Current market signal: Market Steady.

Is the market taking the favorite in Seattle Seahawks vs Arizona Cardinals?

Current market signal: Dog Taking Support.

Is the total dropping for Seattle Seahawks vs Arizona Cardinals?

Current totals signal: Total Steady.

Is the total rising for Seattle Seahawks vs Arizona Cardinals?

Current totals signal: Total Steady.

Where to watch Seattle Seahawks vs Arizona Cardinals?

You can watch this game on FOX. For the latest broadcast details, see Where to Watch.

Where to stream Seattle Seahawks vs Arizona Cardinals?

You can stream this game on FOX One.

What is the best free prop bet for Seattle Seahawks vs Arizona Cardinals?

Remi's Still Searching

What is the biggest matchup edge for Seattle Seahawks vs Arizona Cardinals?

Seattle owns the clearest edge through Jaxon Smith-Njigba against Arizona's secondary. He led the NFL in receiving yards and produced 172 yards across two Cardinals games last season. With Seattle laying 10, sustained chunk gains can create separation without requiring high play volume, while Arizona's offense faces the league's best 2025 scoring defense.

REMI AI PERFORMANCE

NFL Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement. We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

Matchup Seattle Seahawks vs. Arizona Cardinals
Game Date September 20, 2026
Venue State Farm Stadium
RECENT COMPLETED PICKS

AI NFL PAST PICKS

29-22 56.9% WIN
GAME
LEAN
WIN %
UNITS
RESULT
HOU@NE
DRAKE MAYE OVER 0.5 INT
55.1%
5
WIN
LAR@CHI
KYREN WILLIAMS OVER 59.5 RUSH YDS
55.5%
5
WIN
SF@SEA
JAUAN JENNINGS OVER 3.5 RECEPTIONS
56.8%
6
LOSS
BUF@DEN
BO NIX OVER 243.5 PASS + RUSH YDS
55.2%
5
WIN
SF@SEA
SF +7
56.8%
6
LOSS
HOU@PIT
UNDER 38.5
53.4%
2
WIN
HOU@PIT
AARON RODGERS UNDER 21.5 PASS COMP
54.5%
4
WIN
LAC@NE
DRAKE MAYE OVER 0.5 INT THROWN
56.1%
6
WIN
BUF@JAC
TRAVIS ETIENNE UNDER 81.5 RUSH + RECV YDS
54.2%
4
LOSS
SF@PHI
SF +6.5
54.7%
4
WIN
LAC@NE
LAC +3.5
57.1%
7
LOSS
LAR@CAR
MATTHEW STAFFORD UNDER 33.5 PASS ATT
53.5%
3
LOSS
GB@CHI
CALEB WILLIAMS UNDER 0.5 INT THROWN
55.1%
5
LOSS
BAL@PIT
DERRICK HENRY OVER 99.5 RUSH + REC YDS
55.9%
5
WIN
DET@CHI
JAHMYR GIBBS ANYTIME TD
56.8%
6
WIN
IND@HOU
CJ STROUD OVER 221.5 PASS + RUSH YDS
55.4%
5
LOSS
TEN@JAC
JAC -13.5
56.3%
6
WIN
CLE@CIN
CIN -7.5
53.8%
3
LOSS
DAL@NYG
OVER 49.5
54.6%
4
WIN
CAR@TB
BRYCE YOUNG UNDER 0.5 INT
55.2%
5
LOSS
SEA@SF
KENNETH WALKER III UNDER 11.5 RUSH ATT
55.3%
5
LOSS
CAR@TB
BAKER MAYFIELD OVER 0.5 INT
54.1%
4
WIN
SEA@SF
CHRISTIAN MCCAFFREY OVER 5.5 RECEPTIONS
56.7%
6
WIN
LAR@ATL
KYLE PITS OVER 54.5 RECV YDS
55.7%
5
LOSS
LAR@ATL
BIJAN ROBINSON UNDER 44.5 RECV YDS
54.3%
4
WIN
CHI@SF
CALEB WILLIAMS OVER 224.5 PASS YDS
54.1%
4
WIN
JAC@IND
MICHAEL PITTMAN OVER 49.5 RECV YDS
55.2%
5
LOSS
PIT@CLE
CLE +4.5
56.9%
6
WIN
ARI@CIN
CIN -7
58.8%
8
WIN
TB@MIA
TB -4.5
55.2%
5
LOSS
NYG@LV
NYG -2
54.3%
4
WIN
NE@NYJ
NE -13.5
53.9%
3
WIN
NO@TEN
NO -1
56.0%
5
WIN
NYG@LV
UNDER 41.5
53.7%
3
LOSS
HOU@LAC
CJ STROUD OVER 0.5 INT
55.5%
5
WIN
DAL@WAS
DAL -8.5
54.1%
4
LOSS
DEN@KC
RJ HARVEY ANYTIME TD
54.4%
4
WIN
DAL@WAS
TERRY MCLAURIN ANYTIME TD
53.9%
3
LOSS
SF@IND
BROCK PURDY OVER 0.5 INT
55.2%
5
WIN
SF@IND
MICHAEL PITTMAN JR OVER 3.5 RECEPTIONS
54.2%
4
WIN
SF@IND
SF -4.5
56.8%
6
WIN
LV@HOU
NICO COLLINS ANYTIME TD
56.3%
6
LOSS
LAC@DAL
JAVONTE WILLIAMS UNDER 82.5 RUSH + RECV YDS
55.2%
5
WIN
JAC@DEN
TREVOR LAWRENCE UNDER 251.5 PASS + RUSH YDS
57.4%
7
LOSS
LV@HOU
HOU -14
54.6%
4
LOSS
BUF@CLE
CLE +10.5
54.9%
4
WIN
MIN@NYG
MIN -2.5
56.3%
6
WIN
TB@CAR
TB -3
53.1%
3
LOSS
JAC@DEN
DEN -3.5
53.6%
3
LOSS
KC@TEN
KC -2.5
54.6%
4
LOSS
NE@BAL
NE +3.5
56.4%
6
WIN
Past performance is not a guarantee of future results. Picks are displayed for informational purposes only.