Titans vs. 49ers
FREE NFL AI Predictions
December 14, 2025
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Dec 14, 2025
Start Time: 4:25 PM EST​
Venue: ​
49ers Record:
Titans Record:
OPENING ODDS
TEN Moneyline:
SF Moneyline:
TEN Spread: 0
SF Spread:
Over/Under:
TEN
Betting Trends
SF
Betting Trends
MATCHUP TRENDS
TEN vs. SF
Best Prop Bet
LIVE NFL ODDS
NFL ODDS COMPARISON
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VS. SPREAD
295-209
NET UNITS
(INCL VIG)
+417.7
NET PROFIT
(INCL VIG)
$100/UNIT
$41,768
VS. SPREAD
1519-1315
NET UNITS
(INCL VIG)
+312.6
NET PROFIT
(INCL VIG)
$100/UNIT
$31,258
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Tennessee vs San Francisco AI Prediction:
Free NFL Betting Insights for 12/14/25
Titans AI Preview

Credit: USA TODAY/IMAGN
49ers AI Preview
Titans vs. 49ers FREE Prop Pick
Remi is pouring through loads of datapoints on each player. In fact, anytime the Titans and 49ers play there’s always several intriguing angles to key in on. Not to mention games played at in Dec seemingly never follow normal, predictable patterns.
Tennessee vs. San Francisco NFL AI Pick

Remi, our AI sports genius, has been pouring over mountains of data from every facet between the Titans and 49ers and using recursive machine learning and kick-ass AI to crunch the data to a single cover probability.
Interestingly enough, the data has been most focused on the unproportionally assigned emphasis knucklehead sportsbettors often put on Tennessee’s strength factors between a Titans team going up against a possibly strong 49ers team. In reality, the true game analytics appear to reflect a slight lean against one Vegas line in particular.
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