Colts vs Jaguars Prediction — AI Finds CAN'T MISS NFL Lines & Props (Dec 07)
Updated: 2025-11-30T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.
GAME INFO
Date: Dec 07, 2025
Start Time: 1:00 PM EST
Venue:
Jaguars Record:
Colts Record:
OPENING ODDS
IND Moneyline:
JAX Moneyline:
IND Spread: 0
JAX Spread:
Over/Under:
IND
Betting Trends
JAX
Betting Trends
MATCHUP TRENDS
IND vs. JAX
Best Prop Bet
LIVE NFL ODDS
NFL ODDS COMPARISON
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Indianapolis vs Jacksonville Prediction & Odds:
Free NFL Betting Insights for 12/7/25
Indianapolis Colts NFL Preview
Credit: USA TODAY/IMAGN
Jacksonville Jaguars NFL Preview
Indianapolis vs. Jacksonville Prop Picks (AI)
Indianapolis vs. Jacksonville Prediction (AI)
Remi, our AI sports algorithm, has been pouring over millions of data from every simulation between the Colts and Jaguars and using recursive machine learning and industry leading AI to boil down the data to a single cover probability.
The Algorithm has been most keyed in on the unproportionally assigned weight knucklehead sportsbettors often put on Jacksonville’s strength factors between a Colts team going up against a possibly healthy Jaguars team. Trends look to say the true game analytics might reflect a strong lean against one Vegas line in particular.
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Below is our current AI Indianapolis vs Jacksonville picks, computer picks Colts vs Jaguars, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
|---|---|---|---|---|---|---|
| ACTIVE PICKS LOCKED - SEE NOW | ||||||
These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NFL Schedule.
Colts Betting Trends
Jaguars Betting Trends
Colts vs. Jaguars Matchup Trends
Indianapolis vs. Jacksonville Game Info
What time does Indianapolis vs Jacksonville start on December 07, 2025?
Indianapolis vs Jacksonville starts on December 07, 2025 at 1:00 PM EST.
What are the opening odds for Indianapolis vs Jacksonville?
Spread: Jacksonville
Moneyline: Indianapolis , Jacksonville
Over/Under:
What are the records for Indianapolis vs Jacksonville?
Indianapolis: | Jacksonville:
What is the AI best bet for Indianapolis vs Jacksonville?
. Prices move—always shop for the best number.
What are Indianapolis trending bets?
IND trend:
What are Jacksonville trending bets?
JAX trend:
Where can I find AI Picks for Indianapolis vs Jacksonville?
See our latest NFL picks and odds pages for 2025 to compare prices before you bet.
Indianapolis vs. Jacksonville Odds
Remi is pouring through loads of data points on each team. In fact, anytime the Indianapolis vs Jacksonville trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme travel distance seemingly never follow normal, predictable patterns.
Indianapolis vs Jacksonville Opening Odds
IND Moneyline:
JAX Moneyline:
IND Spread: 0
JAX Spread:
Over/Under:
Indianapolis vs Jacksonville Live Odds
| Games | PTS | ML | SPR | O/U | |
|---|---|---|---|---|---|
|
Oct 23, 2025 8:15PM EDT
Minnesota Vikings
Los Angeles Chargers
10/23/25 8:15PM
Vikings
Chargers
|
–
–
|
+159
-185
|
+3.5 (-115)
-3.5 (-105)
|
O 45 (-110)
U 45 (-110)
|
|
|
Oct 26, 2025 1:00PM EDT
Cleveland Browns
New England Patriots
10/26/25 1PM
Browns
Patriots
|
–
–
|
+290
-360
|
+7 (-110)
-7 (-110)
|
O 40.5 (-110)
U 40.5 (-110)
|
|
|
Oct 26, 2025 1:00PM EDT
Buffalo Bills
Carolina Panthers
10/26/25 1PM
Bills
Panthers
|
–
–
|
-400
+320
|
-7.5 (-105)
+7.5 (-115)
|
O 45.5 (-110)
U 45.5 (-110)
|
|
|
Oct 26, 2025 1:00PM EDT
New York Jets
Cincinnati Bengals
10/26/25 1PM
Jets
Bengals
|
–
–
|
+235
-280
|
+6.5 (-110)
-6.5 (-110)
|
O 44.5 (-105)
U 44.5 (-115)
|
|
|
Oct 26, 2025 1:00PM EDT
Chicago Bears
Baltimore Ravens
10/26/25 1PM
Bears
Ravens
|
–
–
|
+253
-305
|
+7 (-120)
-7 (+100)
|
O 50.5 (-110)
U 50.5 (-110)
|
|
|
Oct 26, 2025 1:00PM EDT
New York Giants
Philadelphia Eagles
10/26/25 1PM
Giants
Eagles
|
–
–
|
+317
-395
|
+7 (-105)
-7 (-115)
|
O 44 (-110)
U 44 (-110)
|
|
|
Oct 26, 2025 1:00PM EDT
San Francisco 49ers
Houston Texans
10/26/25 1PM
49ers
Texans
|
–
–
|
+105
-125
|
+1 (-105)
-1 (-115)
|
O 41.5 (-110)
U 41.5 (-110)
|
|
|
Oct 26, 2025 1:00PM EDT
Miami Dolphins
Atlanta Falcons
10/26/25 1PM
Dolphins
Falcons
|
–
–
|
+280
-350
|
+7 (-110)
-7 (-110)
|
O 44.5 (-110)
U 44.5 (-110)
|
|
|
Oct 26, 2025 4:05PM EDT
Tampa Bay Buccaneers
New Orleans Saints
10/26/25 4:05PM
Buccaneers
Saints
|
–
–
|
-215
+183
|
-4 (-110)
+4 (-110)
|
O 46.5 (-110)
U 46.5 (-110)
|
|
|
Oct 26, 2025 4:25PM EDT
Dallas Cowboys
Denver Broncos
10/26/25 4:25PM
Cowboys
Broncos
|
–
–
|
+146
-170
|
+3.5 (-120)
-3.5 (+100)
|
O 50.5 (-110)
U 50.5 (-110)
|
|
|
Oct 26, 2025 4:25PM EDT
Tennessee Titans
Indianapolis Colts
10/26/25 4:25PM
Titans
Colts
|
–
–
|
+750
-1200
|
+14 (-115)
-14 (-105)
|
O 47 (-110)
U 47 (-110)
|
|
|
Oct 26, 2025 8:20PM EDT
Green Bay Packers
Pittsburgh Steelers
10/26/25 8:20PM
Packers
Steelers
|
–
–
|
-175
+150
|
-3 (-120)
+3 (+100)
|
O 45 (-110)
U 45 (-110)
|
|
|
Oct 27, 2025 8:15PM EDT
Washington Commanders
Kansas City Chiefs
10/27/25 8:15PM
Commanders
Chiefs
|
–
–
|
+465
-630
|
+10.5 (-115)
-10.5 (-105)
|
O 48 (-105)
U 48 (-115)
|
|
|
Oct 30, 2025 8:15PM EDT
Baltimore Ravens
Miami Dolphins
10/30/25 8:15PM
Ravens
Dolphins
|
–
–
|
-430
+340
|
-8 (-110)
+8 (-110)
|
O 50.5 (-110)
U 50.5 (-110)
|
|
|
Nov 2, 2025 1:00PM EST
Chicago Bears
Cincinnati Bengals
11/2/25 1PM
Bears
Bengals
|
–
–
|
-120
+102
|
pk
pk
|
O 49.5 (-110)
U 49.5 (-110)
|
|
|
Nov 2, 2025 1:00PM EST
Indianapolis Colts
Pittsburgh Steelers
11/2/25 1PM
Colts
Steelers
|
–
–
|
-136
+116
|
-2.5 (-110)
+2.5 (-110)
|
O 48.5 (-110)
U 48.5 (-110)
|
NFL Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Indianapolis Colts vs. Jacksonville Jaguars on December 07, 2025 at .
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our NFL odds pages, and compare prices before you place a bet.
| NFL |
LEAN | %WIN | UNITS | RESULT |
|---|---|---|---|---|
| TB@DET | RACHAAD WHITE UNDER 14.5 RUSH ATT | 54.4% | 4 | WIN |
| NE@TEN | NE -6.5 | 55.2% | 5 | WIN |
| CAR@NYJ | CAR -110 | 57.4 | 4 | WIN |
| PHI@MIN | PHI -130 | 58.0% | 6 | WIN |
| GB@ARI | ARI +7 | 54.8% | 5 | WIN |
| NO@CHI | NO +4.5 | 57.4% | 7 | LOSS |
| WAS@DAL | JAYDEN DANIELS 1H RUSH YDS OVER 22.5 | 56.1% | 5 | WIN |
| GB@ARI | JORDAN LOVE 1Q PASS YDS OVER 54.5 | 56.6% | 6 | WIN |
| PIT@CIN | JONNU SMITH RECEPTIONS OVER 3.5 | 55.3% | 5 | LOSS |
| BUF@ATL | BUF -3.5 | 54.7% | 4 | LOSS |
| CHI@WAS | JAYDEN DANIELS OVER 1.5 PASS TDS | 56.6% | 6 | WIN |
| TEN@LV | UNDER 42 | 54.8% | 3 | WIN |
| DET@KC | DET +2.5 | 55.7% | 7 | LOSS |
| SEA@JAC | SEA -112 | 55.7% | 5 | WIN |
| LAC@MIA | LAC -3.5 | 54.0% | 3 | LOSS |
| ARI@IND | IND -8.5 | 55.6% | 5 | LOSS |
| TEN@LV | TEN +4.5 | 56.7% | 6 | LOSS |
| LAR@BAL | LAR -7 | 56.2% | 6 | WIN |
| SF@TB | SF +3.5 | 57.2% | 7 | LOSS |
| CLE@PIT | JAYLEN WARREN UNDER 46.5 RUSH YDS | 54.4% | 4 | LOSS |
| DEN@NYJ | BREECE HALL OVER 26.5 RECV YDS | 55.0% | 4 | LOSS |
| KC@JAC | UNDER 45.5 | 54.9% | 3 | LOSS |
| KC@JAC | PATRICK MAHOMES UNDER 23.5 PASS COMP | 56.6% | 6 | LOSS |
| HOU@BAL | HOU -125 | 58.5% | 7 | WIN |
| DET@CIN | DET -10 | 55.6% | 5 | WIN |
| DAL@NYJ | NYJ +1.5 | 53.7% | 3 | LOSS |
| TB@SEA | TB +3.5 | 54.9% | 4 | WIN |
| TEN@ARI | ARI -7 (BUY 0.5) | 54.9% | 4 | LOSS |
| DEN@PHI | DEN +4.5 | 57.5% | 7 | WIN |
| MIA@CAR | TETAIROA MCMILLAN OVER 58.5 RECV YDS | 54.5% | 4 | WIN |
| LV@IND | ASHTON JEANTY UNDER 67.5 RUSH YDS | 54.4% | 4 | WIN |
| SF@LAR | DEMARCUS ROBINSON OVER 29.5 RECV YDS | 55.7% | 5 | WIN |
| NYJ@MIA | NYJ +3 | 53.8 | 3 | LOSS |
| CIN@DEN | DEN -7.5 | 54.8 | 4 | WIN |
| NYJ@MIA | OVER 44 | 52.9% | 2 | WIN |
| CIN@DEN | UNDER 44.5 | 53.7% | 3 | WIN |
| NYJ@MIA | GARRETT WILSON UNDER 9 TARGETS | 53.7% | 3 | WIN |
| CIN@DEN | TEE HIGGINS OVER 6.5 RECV TARGETS | 55.5% | 5 | LOSS |
| WAS@ATL | ATL -2.5 | 54.3 | 4 | WIN |
| BAL@KC | BAL -2.5 | 56.3% | 6 | LOSS |
| TEN@HOU | TEN +7.5 | 57.9% | 7 | LOSS |
| LAC@NYG | LAC -6 | 57.3% | 7 | LOSS |
| NO@BUF | UNDER 48.5 | 55.1% | 3 | LOSS |
| GB@DAL | JAVONTE WILLIAMS UNDER 72.5 RUSH + REC YDS | 55.5% | 5 | LOSS |
| CAR@NE | DRAKE MAYE TO THROW AN INT | 56.6% | 6 | LOSS |
| SEA@ARI | SEA -125 | 57.7% | 6 | WIN |
| SEA@ARI | KYLER MURRAY TO THROW AN INT | 56.6% | 6 | WIN |
| DET@BAL | JAHMYR GIBBS OVER 0.5 RUSH TDS | 55.8% | 5 | WIN |
| DAL@CHI | DAL -120 | 58.7% | 6 | LOSS |
| PIT@NE | PIT -116 | 60.1% | 6 | WIN |
| ATL@CAR | ATL -4.5 | 55.4% | 5 | LOSS |